A convenient method for the relative and absolute quantification of lipid components in liposomes by < sup > 1 < /sup > H- and < sup > 31 < /sup > P-NMR-spectroscopy
CONCLUSION: Liposome preparations containing POPC, POPE, DOPC, DPPC, TACH, and PEG-ceramide can be reliably characterized and quantified by 1H-NMR and 31P-NMR spectroscopy at 600MHz in the μmol range.PMID:38615786 | DOI:10.1016/j.chemphyslip.2024.105395 (Source: Chemistry and Physics of Lipids)
Source: Chemistry and Physics of Lipids - April 14, 2024 Category: Lipidology Authors: Andreas H Franz Nataliya M Samoshina Vyacheslav V Samoshin Source Type: research
Impact of LDLR polymorphisms on lipid levels and atorvastatin ’s efficacy in a northern Chinese adult Han cohort with dyslipidemia
Dyslipidemia, a significant risk factor for atherosclerotic cardiovascular disease (ASCVD), is influenced by genetic variations, particularly those in the low-density lipoprotein receptor (LDLR) gene. This stu... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 14, 2024 Category: Lipidology Authors: Hong-Liang Zhao, Yang You, Yan Tian, Luyan Wang, Yongqiang An, Guoqiang Zhang, Chang Shu, Mingxin Yu, Yihua Zhu, Qian Li, Yanwei Zhang, Ningling Sun, Songnian Hu and Gang Liu Tags: Research Source Type: research
Effects of portable pedal machines at work on lipoprotein subfraction profile in sedentary workers – the REMOVE study
Sedentary behaviour at work is a major cause of atherosclerosis, particularly in tertiary workers. However, no studies have ever assessed the effect of active workstation on lipoprotein subfraction profile. Th... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 14, 2024 Category: Lipidology Authors: Hijrah Nasir, Frederic Dutheil, Ines Ramos, Terry Guirado, Sarah de Saint-Vincent, David Thivel, Lore Metz and Martine Duclos Tags: Research Source Type: research
Increased visceral fat area to skeletal muscle mass ratio is positively associated with the risk of metabolic dysfunction-associated steatotic liver disease in a Chinese population
The diagnosis and comprehension of nonalcoholic fatty liver disease (NAFLD), recently redefined as metabolic dysfunction-associated steatotic liver disease (MASLD) are gaining a better understanding. In this s... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 14, 2024 Category: Lipidology Authors: Chenbing Liu, Nan Li, Di Sheng, Yahong Shao, Lihong Qiu, Chao Shen and Zhong Liu Tags: Research Source Type: research
Study of association of leptin with leukocyte telomere length in a Chinese rural population
Previous studies have demonstrated the relationship between adipocyte factors, insulin resistance, and other indicators with telomere length. However, these studies did not consider the influence of changes in... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 13, 2024 Category: Lipidology Authors: Juan Li, Chan Yang, Yadi Zhang, Qingqing Li, Xiaowei Liu, Yuhong Zhang and Yi Zhao Tags: Research Source Type: research
The association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and kidney stones: a cross-sectional study
The relationship between the NHHR and kidney stone risk remains unknown. The purpose of this study was to evaluate the association between adult NHHR and kidney stone occurrence in USA. (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 13, 2024 Category: Lipidology Authors: Hujian Hong, Yijiang He, Zhiqiang Gong, Jilong Feng and Yanli Qu Tags: Research Source Type: research
Remnant cholesterol is associated with the progression and regression of metabolic dysfunction-associated steatotic liver disease in Chinese adults
The prevalence of nonalcoholic fatty liver disease (NAFLD) has progressively increased over recent decades with increased rates of obesity and the rapid growth of the ageing population, affecting approximately 29% of the Chinese population (1). In addition to intrahepatic diseases such as liver cirrhosis and hepatocellular carcinoma, NAFLD has been demonstrated to increase the risks of multiple extrahepatic complications, including type 2 diabetes (T2DM), chronic kidney disease, cardiovascular disease (CVD), and even extrahepatic tumours (2,3). (Source: Journal of Clinical Lipidology)
Source: Journal of Clinical Lipidology - April 10, 2024 Category: Lipidology Authors: Wen Guo, Jing Lu, Xiaona Li, Xin Zhao, Nianzhen Xu, Qingqing Diao, Jue Jia, Qun Zhang Tags: Original Research Source Type: research
Evaluation of the therapeutic efficacy of different doses of LT4 in pregnant women with high-normal TSH levels and TPOAb positivity in the first half of pregnancy
The objective was to investigate the efficacy of different doses of levothyroxine therapy among pregnant women exhibiting high-normal thyroid stimulating hormone levels and positive thyroid peroxidase antibodi... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 10, 2024 Category: Lipidology Authors: Xin Tian, Yajuan Xu, Yanjie Ban, Jingjing Li, Lin Hu, Dong Liu, Lulu Hu, Zongzong Sun, Miao Zhang, Chenchen Zhang, Yixin Wang and Pengkun Lin Tags: Research Source Type: research
Association between obstructive sleep apnea and visceral adiposity index and lipid accumulation product: NHANES 2015 –2018
Obesity refers to a significant contributor to the development of obstructive sleep apnea (OSA). Early prediction of OSA usually leads to better treatment outcomes, and this study aims to employ novel metaboli... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 10, 2024 Category: Lipidology Authors: Tingfeng Zhou, Shihao Chen, Jiesheng Mao, Pei Zhu, Xinru Yu and Renyu Lin Tags: Research Source Type: research
Alirocumab and cardiovascular outcomes according to sex and lipoprotein(a) after acute coronary syndrome: ODYSSEY OUTCOMES
Women are often underrepresented in clinical trials, leading to uncertainty in subgroup analyses by sex and lower quality data to guide evidence-based therapy.1,2 While many individual trials are inconclusive, patient-level meta-analyses show that women with established cardiovascular disease benefit from statin therapy to the same degree as men.3 However, sex-specific data for non-statin lipid-lowering therapies are sparse.2 A recent statement by the European Society of Atherosclerosis highlighted differences in lipoprotein concentrations through the life course in women versus men, as well as sex differences in the relat...
Source: Journal of Clinical Lipidology - April 9, 2024 Category: Lipidology Authors: Vera A. Bittner, Gregory G. Schwartz, Deepak L. Bhatt, Terrance Chua, H. Asita De Silva, Rafael Diaz, Shaun G. Goodman, Robert A. Harrington, J. Wouter Jukema, Jennifer McGinniss, Robert Pordy, Genevieve Garon, Michel Scemama, Harvey D. White, Ph. Gabriel Tags: Original Research Source Type: research
Sex, Racial, Ethnic, and Geographical Disparities in Major Adverse Cardiovascular Outcome of Glucagon-like peptide-1 receptor agonists among patients with and without diabetes mellitus: A Meta-analysis of Placebo-Controlled Randomized Controlled Trials
Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have emerged as a first-line drug in treating type 2 diabetes mellitus (T2DM).1 GLP-1RAs have also been found to significantly reduce the risk of major adverse cardiovascular events (MACE) in patients with T2DM, as demonstrated by multiple large cardiovascular outcome trials (CVOTs).2, 3 The LEADER (Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results) trial (2016), which aimed to determine the cardiovascular (CV) effects of liraglutide marked a turning point and was the first to show a reduction in major adverse cardiovascular events (...
Source: Journal of Clinical Lipidology - April 4, 2024 Category: Lipidology Authors: Frederick Berro Rivera, Nathan Ross B. Bantayan, John Paul Aparece, Linnaeus Louisse A. Cruz, John Vincent Magallong, Polyn Luz Pine, Anne Mira Nicca Idian-Javier, Grace Nooriza O. Lumbang, Edgar V. Lerma, Kyla M. Lara-Breitinger, Martha Gulati, Krishnasw Tags: Original Research Source Type: research
Association of the habitual dietary intake with the fatty liver index and effect modification by metabotypes in the population-based KORA-Fit study
Non-alcoholic fatty liver disease (NAFLD) is an emerging threat for public health with diet being a major risk factor in disease development and progression. However, the effects of habitual food consumption o... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 4, 2024 Category: Lipidology Authors: M. Schepp, D. Freuer, N. Wawro, A. Peters, M. Heier, D. Teupser, C. Meisinger and J. Linseisen Tags: Research Source Type: research
Long-term Cardiovascular Outcomes in a Population-Based Multicentric Cohort of Northern Portugal: Validation of the ESC/EAS Prognostic Risk Classification
The rising prevalence of cardiovascular (CV) risk factors in Portugal translates into more than 35 000 annual deaths due to CV diseases, representing 30% of the total mortality in 2019 1,2. Moreover, CV risk factors such as dyslipidemia, obesity, hypertension, type 2 diabetes, smoking, coronary artery disease, history of stroke, myocardial infarction, among others can significantly increase the risk of subsequent CV events 3. (Source: Journal of Clinical Lipidology)
Source: Journal of Clinical Lipidology - April 4, 2024 Category: Lipidology Authors: Cristina Gavina, Daniel Seabra Carvalho, Marta Afonso-Silva, Daniela Brand ão Abreu, Mariana Canelas-Pais, Tiago Taveira-Gomes, Francisco Araújo Tags: Original Research Source Type: research
The novel molecular mechanism of pulmonary fibrosis: insight into lipid metabolism from reanalysis of single-cell RNA-seq databases
Pulmonary fibrosis (PF) is a severe pulmonary disease with limited available therapeutic choices. Recent evidence increasingly points to abnormal lipid metabolism as a critical factor in PF pathogenesis. Our l... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 3, 2024 Category: Lipidology Authors: Xiangguang Shi, Yahui Chen, Mengkun Shi, Fei Gao, Lihao Huang, Wei Wang, Dong Wei, Chenyi Shi, Yuexin Yu, Xueyi Xia, Nana Song, Xiaofeng Chen, J örg H. W. Distler, Chenqi Lu, Jingyu Chen and Jiucun Wang Tags: Review Source Type: research
Association of birth weight with type 2 diabetes mellitus and the mediating role of fatty acids traits: a two-step mendelian randomization study
Observational studies have suggested an association between birth weight and type 2 diabetes mellitus, but the causality between them has not been established. We aimed to obtain the causal relationship betwee... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 2, 2024 Category: Lipidology Authors: Limin Cao, Yahui Wen, Keyi Fan, Qiwei Wang, Yaochen Zhang, Zhenglong Li, Nan Wang and Xinhua Zhang Tags: Research Source Type: research
