Establishing non-fasting reference values for plasma lipids levels based on age, sex, and puberty stage in a French-Canadian pediatric population
Dyslipidemias, including familial hypercholesterolemia (FH), are a significant risk factor for cardiovascular diseases. FH is a genetic disorder resulting in elevated levels of low-density lipoprotein choleste... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - February 22, 2024 Category: Lipidology Authors: Sophie Bouhour, Rosalie Plantef ève, Virginie Gillet, Armita Abolghasemi, Fatima Zahra Bouchouirab, Andrea A. Baccarelli, Larissa Takser and Artuela Çaku Tags: Research Source Type: research
Association of triglyceride glucose-body mass index and hemoglobin glycation index with heart failure prevalence in hypertensive populations: a study across different glucose metabolism status
The Triglyceride glucose-body mass index (TyG-BMI) and hemoglobin glycation index (HGI) are well-established surrogate markers for insulin resistance. Nevertheless, the extent to which these markers offer addi... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - February 22, 2024 Category: Lipidology Authors: Rupeng Wang, Ce Chen, Guiyu Xu and Zening Jin Tags: Research Source Type: research
Statins Use for Primary Prevention of Cardiovascular Disease: A Population-based Digitally Enabled Real-world Evidence Cross-Sectional Study in Primary Care in Brazil
Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality worldwide and especially in low and middle-income countries (LMICs).1 Statins represent a key strategy to prevent dyslipidemia-associated CVD morbidity and mortality, because of their reduction on LDL-cholesterol (LDL-C) concentrations, as well as anti-inflammatory and other plaque-stabilization effects.2-4 Although individuals without previous CVD are at lower absolute risk, at least half of all vascular events occur among them. (Source: Journal of Clinical Lipidology)
Source: Journal of Clinical Lipidology - February 20, 2024 Category: Lipidology Authors: Karla Santo, Raul D. Santos, Alysson Nathan Girotto, Josue Nieri, Frederico Monfardini, Priscila Raupp, Pedro Marton Pereira, Otavio Berwanger, M. Julia Machline-Carrion Tags: Original Research Source Type: research
Topical rhubarb charcoal-crosslinked chitosan/silk fibroin sponge scaffold for the repair of diabetic ulcers improves hepatic lipid deposition in db/db mice via the AMPK signalling pathway
Type 2 diabetes mellitus (T2DM) is closely linked to metabolic syndrome, characterised by insulin resistance, hyperglycaemia, abnormal lipid metabolism, and chronic inflammation. Diabetic ulcers (DUs) comprise... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - February 20, 2024 Category: Lipidology Authors: Qi Tan, Qifeng He, Ze Peng, Xin Zeng, Yuzhe Liu, Dong Li, Shang Wang and Jianwei Wang Tags: Research Source Type: research
Adiponectin protects against myocardial ischemia –reperfusion injury: a systematic review and meta-analysis of preclinical animal studies
Myocardial ischemia –reperfusion injury (MIRI) is widespread in the treatment of ischemic heart disease, and its treatment options are currently limited. Adiponectin (APN) is an adipocytokine with cardioprotect... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - February 17, 2024 Category: Lipidology Authors: Hongyi Yue, Qunhui Zhang, Senhao Chang, Xinjie Zhao, Mengjie Wang and Wenhua Li Tags: Review Source Type: research
Phosphorylation: new star of pathogenesis and treatment in steatotic liver disease
Steatotic liver disease poses a serious threat to human health and has emerged as one of the most significant burdens of chronic liver disease worldwide. Currently, the research mechanism is not clear, and the... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - February 17, 2024 Category: Lipidology Authors: Tiansu Lv, Yan Lou, Qianhua Yan, Lijuan Nie, Zhe Cheng and Xiqiao Zhou Tags: Research Source Type: research
TRP channels associated with macrophages as targets for the treatment of obese asthma
Globally, obesity and asthma pose significant health challenges, with obesity being a key factor influencing asthma. Despite this, effective treatments for obese asthma, a distinct phenotype, remain elusive. S... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - February 17, 2024 Category: Lipidology Authors: Wenzhao Zhu, Dinxi Bai, Wenting Ji and Jing Gao Tags: Review Source Type: research
A regulatory element associated to NAFLD in the promoter of DIO1 controls LDL-C, HDL-C and triglycerides in hepatic cells
Genome-wide association studies (GWAS) have identified genetic variants linked to fat metabolism and related traits, but rarely pinpoint causative variants. This limitation arises from GWAS not considering fun... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - February 16, 2024 Category: Lipidology Authors: Casimiro Castillejo-L ópez, José Ramón Bárcenas-Walls, Marco Cavalli, Anders Larsson and Claes Wadelius Tags: Research Source Type: research
Lipoprotein(a) testing in Lipid Clinics across the UK: Results of a national survey
Lipoprotein(a) (Lp(a)) is an independent risk factor for atherosclerotic cardiovascular disease (ASCVD) and calcific aortic valve stenosis(1). (Source: Journal of Clinical Lipidology)
Source: Journal of Clinical Lipidology - February 14, 2024 Category: Lipidology Authors: Saleem Ansari BSc, R Dermot G Neely, Jules Payne, Jaimini Cegla Tags: Brief Communication Source Type: research
Association of Lipoprotein (a) with Peri-coronary Inflammation in Persons with and without HIV Infection
Persons with human immunodeficiency virus (HIV) (PWH) have an approximately 2-fold increased risk of developing cardiovascular disease (CVD) than those without HIV (PWoH)1-2. This increased CVD risk may be due to chronic systemic inflammation and immune activation in PWH3. Lipoprotein (a) (Lp(a)), a subclass of low-density lipoprotein (LDL), is an independent atherosclerotic risk factor in PWoH4-5. While elevated Lp(a) levels may occur in PWH6, few studies have investigated the association of Lp(a) and subclinical atherosclerosis7-8, and no studies have evaluated its association with peri-coronary inflammation. (Source: Jo...
Source: Journal of Clinical Lipidology - February 14, 2024 Category: Lipidology Authors: Erin Zisman, Mian Hossain, Nicholas T. Funderburg, Robert Christenson, Jean Jeudy, Shana Burrowes, Allison G. Hays, Nivya George, Michael L. Freeman, Heather Rebuck, Sarah E. Mitchell, Michael Miller, Shashwatee Bagchi Tags: Original Research Source Type: research
Assessment of whole-body and regional body fat using abdominal quantitative computed tomography in Chinese women and men
Being overweight or obese has become a serious public health concern, and accurate assessment of body composition is particularly important. More precise indicators of body fat composition include visceral adi... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - February 14, 2024 Category: Lipidology Authors: Jinci Mai, Qiulian Wu, Huanhua Wu, Chunyuan Zeng, Yingxin Li, Jingjie Shang, Biao Wu, Qijun Cai, Junbi Du and Jian Gong Tags: Research Source Type: research
Joint association of physical activity and diet quality with dyslipidemia: a cross-sectional study in Western China
This study aims to investigate the prevalence of dyslipidemia and assess the joint association of physical activity (PA) and diet quality on dyslipidemia risk in urban areas of Xinjiang. (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - February 10, 2024 Category: Lipidology Authors: Munire Mutalifu, Qian Zhao, Ying Wang, Xieyire Hamulati, Yu-Shan Wang, Lei Deng, Niyaziaili Adili, Fen Liu, Yi-Ning Yang and Xiao-Mei Li Tags: Research Source Type: research
Associations of the triglyceride-glucose index and remnant cholesterol with coronary artery disease: a retrospective study
Remnant cholesterol (RC) represents a low-cost and readily measured lipid index that contributes significantly to residual cardiovascular disease risk. The triglyceride-glucose (TyG) index exhibits a significa... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - February 10, 2024 Category: Lipidology Authors: Xiaosheng Wu, Weiping Qiu, Houlin He, Guojun Zhao and Jianling Liu Tags: Research Source Type: research
Use of Lipid Ratios to Predict Vascular Target Organ Damage in Youth
Elevated triglycerides (TG) and non-high-density lipoprotein cholesterol with reduced high-density lipoprotein cholesterol (HDL-C), known as combined dyslipidemia (CD)1-4, is increasing with the concomitant increase in rates of childhood obesity. The most recent NHANES data have shown that the prevalence of childhood obesity is up to 19% with an estimated 30-60% of obese youth having CD.2,5 This characteristic pattern of obesity and dyslipidemia has been associated with insulin resistance, metabolic syndrome, and type 2 diabetes (T2D) . (Source: Journal of Clinical Lipidology)
Source: Journal of Clinical Lipidology - February 9, 2024 Category: Lipidology Authors: Sarah E. Henson, Elaine M. Urbina Tags: Original Research Source Type: research
The pathogenic mutations of APOA5 in Chinese patients with hyperlipidemic acute pancreatitis
To study the role of gene mutations in the development of severe hypertriglyceridemia (HTG) in patients with hyperlipidemic acute pancreatitis (HLAP), especially different apolipoprotein A5 (APOA5) mutations. (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - February 8, 2024 Category: Lipidology Authors: Yuxin Liu, Si Dai, Shuqi Qin, Jing Zhou, Zhendan Wang and Guojian Yin Tags: Research Source Type: research
