The impact of cigarette smoking on the efficiency of local anesthesia during simple tooth extraction
Conclusion:The amount of local anesthesia used in smoker patients was higher than that in nonsmoker patients, especially if there were symptoms like pain. The duration of smoking and daily cigarette consumption had no effect on the amount and the onset of local anesthesia. (Source: Dental Technology Blog)
Source: Dental Technology Blog - May 12, 2020 Category: Dentistry Source Type: news

Infant with status epilepticus secondary to systemic lidocaine toxicity from topical application - Walters E, Wurster Ovalle V, Yin S, Dribin T.
A previously healthy 11-month-old infant presented to the emergency department in status epilepticus. There was no clear trigger of her seizure activity which resolved with benzodiazepines and fosphenytoin. On further review, her parents disclosed that she... (Source: SafetyLit)
Source: SafetyLit - January 16, 2020 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

What to D.O.: Compounding Pharmacies Can Continue ED Meds (Like Intranasal Lidocaine and Oral Ketamine)
No abstract available (Source: Emergency Medicine News)
Source: Emergency Medicine News - December 1, 2019 Category: Emergency Medicine Tags: What to D.O. Source Type: news

Glydo (Lidocaine HCI Jelly USP, 2%) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 8, 2019 Category: Drugs & Pharmacology Source Type: news

Efficacy and Safety of Pulpal Anesthesia Strategies during Endodontic Treatment of Permanent Mandibular Molars with Symptomatic Irreversible Pulpitis: A Systematic Review and Network Meta-analysis
ConclusionsVery low- to moderate-quality evidence suggests intraosseous injection using 2% lidocaine with 1:100,000 epinephrine or 4% articaine with 1:100,000 epinephrine or buccal and lingual infiltrations of 4% articaine with 1:100,000 epinephrine are superior strategies to achieve pulpal anesthesia during endodontic treatment of mandibular molars with symptomatic irreversible pulpitis. Preoperative NSAIDs or opioids with or without acetaminophen may increase the efficacy of these injections. (Source: Dental Technology Blog)
Source: Dental Technology Blog - October 16, 2019 Category: Dentistry Source Type: news

EMA Panel Backs Anesthetic Spray for Premature Ejaculation EMA Panel Backs Anesthetic Spray for Premature Ejaculation
Senstend, a spray containing lidocaine/prilocaine, can improve ejaculatory control and sexual satisfaction and reduce distress related to ejaculation, the EMA said.International Approvals (Source: Medscape FamilyMedicine Headlines)
Source: Medscape FamilyMedicine Headlines - September 20, 2019 Category: Primary Care Tags: Urology News Alert Source Type: news

Ridge Properties LLC DBA Pain Relief Naturally Issues Voluntary Nationwide Recall of PRE-TAT , Superior Pain and Itch Relief, and Soothing Sore Relief Cream and Gel Products Due to Microbiological Contamination and Superpotency
Ridge Properties LLC DBA Pain Relief Naturally is voluntarily recalling 4 lots of 4% lidocaine topical cream& liquid gel products sold at the consumer level. FDA analysis has found these products to have microbiological contamination and the potency is higher than the labeled amount for lidocaine. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 9, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Ridge Properties LLC DBA Pain Relief Naturally Issues Voluntary Nationwide Recall of PRE-TAT, Superior Pain and Itch Relief, and Soothing Sore Relief Cream and Gel Products Due to Microbiological Contamination and Superpotency
Ridge Properties LLC DBA Pain Relief Naturally is voluntarily recalling 4 lots of 4% lidocaine topical cream& liquid gel products sold at the consumer level. FDA analysis has found these products to have microbiological contamination and the potency is higher than the labeled amount for lidocaine. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 9, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Comparative study of articaine and lidocaine without palatal injection for maxillary teeth extraction
ConclusionThe extraction of permanent maxillary teeth is possible without palatal injections and there is no difference between articaine and lidocaine.Clinical relevanceLocal anesthetic agents are the most frequently administered drugs in dentistry and represent the primary method of pain control for patients undergoing intraoral procedures. (Source: Dental Technology Blog)
Source: Dental Technology Blog - July 10, 2019 Category: Dentistry Source Type: news

Hair in one vail, Aurobindo recalls 88k Lidocaine injections from US
According to a notification put up by the US Drug regulator in its website, these vials were manufactured in India for AuroMedics Pharna LLC. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - April 17, 2019 Category: Pharmaceuticals Source Type: news

Mouthwash Cuts Mucositis Pain, Enough to Make a Difference? Mouthwash Cuts Mucositis Pain, Enough to Make a Difference?
Oral rinse containing doxepin or the combination of diphenhydramine, lidocaine, and antacid may help reduce oral mucositis-related pain in head and neck cancer patients.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - April 17, 2019 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Lidocaine Hydrochloride (Xylocaine) Injection (Updated - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - April 16, 2019 Category: Drugs & Pharmacology Source Type: news

Magic mouthwash effective treatment for mouth sore pain caused by radiation therapy
(Mayo Clinic) 'Magic mouthwash,' an oral rinse containing diphenhydramine, lidocaine and antacids, significantly reduced pain from oral mucositis, mouth sores, in patients receiving radiation therapy for cancers of the head and neck when compared to plaecbo. These were the findings of a multi-institution, randomized, double-blind, placebo-controlled, phase III clinical trial, led by Robert Miller, M.D., an emeritus Mayo Clinic radiation oncologist. Dr. Miller and his colleagues published their findings on Tuesday, April 16, in JAMA. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 16, 2019 Category: Cancer & Oncology Source Type: news

New Anesthetic Proven to Reduce Pain in Pediatric Dentistry
This article is vital research in the arena of pediatric dentistry as it eliminates the need of very painful palatal injections, thus reducing the number of pricks to one. Elimination of painful palatal injections reduces children’s anxiety, thus instilling a positive dental attitude in th em. This research also will lay a cornerstone for further research to explore newer drugs and techniques for better patient compliance.”By reducing the number of injections to one, articaine is setting the groundwork for a more positive pediatric dental experience. As the researchers notes, this study opens the door for additional wo...
Source: Dental Technology Blog - April 15, 2019 Category: Dentistry Source Type: news

Magic Mouthwash effective treatment for mouth sore pain caused by radiation therapy
JACKSONVILLE, Fla. -- "Magic mouthwash," an oral rinse containing diphenhydramine, lidocaine and antacids, significantly reduced pain from oral mucositis, mouth sores, in patients receiving?radiation therapy for cancers of the head and neck when compared to placebo. These were the findings of a multi-institution, randomized, double-blind, placebo-controlled, phase III clinical trial, led by Robert Miller, M.D., [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - April 15, 2019 Category: Databases & Libraries Source Type: news