EMA Panel Backs Anesthetic Spray for Premature Ejaculation EMA Panel Backs Anesthetic Spray for Premature Ejaculation
Senstend, a spray containing lidocaine/prilocaine, can improve ejaculatory control and sexual satisfaction and reduce distress related to ejaculation, the EMA said.International Approvals
CONCLUSIONS: The pharmaceutical therapy that is currently being used in clinical practice for the management of PE is still the main choice globally due to its good efficacy. Surgery may be a choice for patients who are resistant to medication. However, it should be performed cautiously. PMID: 31567373 [PubMed - as supplied by publisher]
ConclusionsWe recommend the initial use of dapoxetine 30 mg OD for PE because it has been tested in largest and better designed clinical trials rather than it is more effective than the other drugs studied. TAs and tramadol 50 mg OD can be used as a viable alternative to oral treatment with SSRIs. PDE5is combined with SSRIs are more effective than SSRI s monotherapy but are also associated with more side effects. PDE5is OD can be recommended to PE patients with ED.
CONCLUSIONSThese data point to a legacy syndrome or syndromes comprising a range of disturbances to sexual function. More detailed studies will require developments in coding systems that recognise the condition(s). Further exploration of these tardive sexual syndromes may yield greater understanding of tardive syndromes in general. PMID: 29733030 [PubMed - as supplied by publisher]
Abstract Penile hypersensitivity plays an important role in premature ejaculation (PE), but differences in penile sensitivity among subtypes of PE are unknown. Therefore, we compared penile sensory thresholds in PE subtypes of lifelong and acquired PE, PE with and without erectile dysfunction (ED), PE with an intravaginal ejaculation latency time ≤1 min and>1 min, and PE with and without orgasmic pleasure perceptual dysfunction. During August 2014 to January 2016, 136 patients with PE were included. Penile warm, cold, and vibratory thresholds were measured. Data of clinical characteristics, sexual life, Prem...
Handy anesthetic'wipes'may help some - - but not all - - guys with premature ejaculation, small study finds
Anesthetic wipes contain 4 percent benzocaine
Researchers from Cornell University found benzocaine-laced wipes desensitize the penis and delay ejaculation, allowing for a significantly longer erection over placebo wipes.
Handy anesthetic 'wipes' may help some -- but not all -- guys with premature ejaculation, small study finds
MONDAY, May 15, 2017 -- Men troubled by the embarrassment of premature ejaculation might soon have an easy way to avoid it, new research suggests. Special " wipes " embedded with a mild anesthetic -- benzocaine -- appear to help reduce premature...
Authors: Dell'Atti L, Galosi AB, Ippolito C Abstract OBJECTIVE: The use of topical local anesthetics in the form of creams, gel or spray is the oldest method of retarding ejaculation. However, several studies have suggested that phosphodiesterase type 5 inhibitors (5-PDEiS) show a potential therapeutic use in the treatment of premature ejaculation (PE). The aim of this study was to compare the efficacy and tolerability of tadalafil-only, tadalafil plus local anesthetic spray (lidocaine), and topical lidocaine spray-only before intercourse on the intravaginal ejaculatory latency time (IELT) of patients with lifelong...