The role of Lesotho community pharmacists in preventing and controlling cardiovascular diseases: The perceived facilitators and barriers
ConclusionsLesotho community pharmacists can potentially improve cardiovascular diseases ’ health outcomes at primary healthcare level through early detection of CVD risk factors, and health promotion. (Source: PLoS One)
Source: PLoS One - April 4, 2024 Category: Biomedical Science Authors: Nthabiseng Florina Motlohi Source Type: research

A preliminary, quantitative study on the use of traditional and complementary medicine by cancer patients seen at the Senkatana oncology clinic, Maseru, Lesotho
CONCLUSIONS: It is concluded that all interviewed cancer patients use TCM. Patients indicated that one of the reasons for using TCM was that they wanted to try everything that could help in their cancer care. Patients further reported that they did not inform their oncologist of their concurrent use of TCM because they had been advised not to use other medicines besides what they are given at the clinic.PMID:38561693 | DOI:10.1186/s12906-024-04388-3 (Source: Cancer Control)
Source: Cancer Control - April 2, 2024 Category: Cancer & Oncology Authors: Mopa A Sooro Thabo S Thoahlane Maseabata V Ramathebane Kabelo A Mputsoe Source Type: research

A preliminary, quantitative study on the use of traditional and complementary medicine by cancer patients seen at the Senkatana oncology clinic, Maseru, Lesotho
The use of traditional and complementary medicine (TCM) by cancer patients remains common in several countries especially in the Sub-Saharan Africa. However, the reasons for use are complex and change with tim... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - April 1, 2024 Category: Complementary Medicine Authors: Mopa A. Sooro, Thabo S. Thoahlane, Maseabata V. Ramathebane and Kabelo A. Mputsoe Tags: Research Source Type: research

Adverse childhood experiences, mental distress, self-harm and suicidality, and cumulative HIV risk by sex in Lesotho
CONCLUSIONS: Differential patterns of associations between ACEs and mental health problems and HIV risk emerged by sex. Scalable, integrated individual and community efforts to prevent ACEs, provide mental health supports, and encourage safer sexual behaviors among those exposed are needed and could benefit youth in Lesotho.PMID:38402043 | DOI:10.1016/j.chiabu.2024.106701 (Source: Child Abuse and Neglect)
Source: Child Abuse and Neglect - February 24, 2024 Category: Child Development Authors: Elizabeth W Perry Mohling Manderley Recinos Japheth Nkiriyehe Kwiringira Erick Phung Connie Olwit Monica H Swahn Greta Massetti Shannon Self-Brown Source Type: research

Adverse childhood experiences, mental distress, self-harm and suicidality, and cumulative HIV risk by sex in Lesotho
CONCLUSIONS: Differential patterns of associations between ACEs and mental health problems and HIV risk emerged by sex. Scalable, integrated individual and community efforts to prevent ACEs, provide mental health supports, and encourage safer sexual behaviors among those exposed are needed and could benefit youth in Lesotho.PMID:38402043 | DOI:10.1016/j.chiabu.2024.106701 (Source: Child Abuse and Neglect)
Source: Child Abuse and Neglect - February 24, 2024 Category: Child Development Authors: Elizabeth W Perry Mohling Manderley Recinos Japheth Nkiriyehe Kwiringira Erick Phung Connie Olwit Monica H Swahn Greta Massetti Shannon Self-Brown Source Type: research

Investigating the Associations between Drought, Poverty, High-Risk Sexual Behaviours, and HIV Incidence in Sub-Saharan Africa: A Cross-Sectional Study
AbstractClimate change is increasing the likelihood of drought in sub-Saharan Africa, where HIV prevalence is high. Drought could increase HIV transmission through various mediating mechanisms; we investigated these associations. We used data on people aged 15 –59 from Population-Based HIV Impact Assessment surveys from 2016 in Eswatini, Lesotho, Tanzania, Uganda, and Zambia. Survey data were geospatially linked to precipitation data for 2014–2016, with local droughts defined as cumulative rainfall between 2014 and 2016 being in<  15th percentile of all 2-year periods over 1981–2016. Using multivariable logistic...
Source: AIDS and Behavior - February 20, 2024 Category: Infectious Diseases Source Type: research

Low body mass index as a predictor of sputum culture conversion and treatment outcomes among patients receiving treatment for multidrug-resistant tuberculosis in Lesotho
CONCLUSIONS: Low BMI was common and associated with the frequency of six-month culture conversion and end-of-treatment outcomes. The association with culture conversion was more pronounced among those not living with HIV. Addressing the myriad factors that drive low BMI in this setting could hasten culture conversion and improve end-of-treatment outcomes. This will require a multipronged approach focused on alleviating food insecurity and enabling prompt diagnosis and treatment of HIV and TB.PMID:38305025 | PMC:PMC10840591 | DOI:10.1080/16549716.2024.2305930 (Source: Global Health Action)
Source: Global Health Action - February 2, 2024 Category: International Medicine & Public Health Authors: Lawrence Oyewusi Chengbo Zeng K J Seung Stephanie Mpinda Mikanda Kunda Carole D Mitnick Makelele Kanu Meseret Tamirat Joalane Makaka Mabatloung Mofolo Refiloe Maime Llang Maama Ninza Senyo Bamidele Oguntoyinbo Lwayi Mayombo Molly F Franke Source Type: research

A community-based child health and parenting intervention to improve child HIV testing, health, and development in rural Lesotho (Early Morning Star): a cluster-randomised, controlled trial
Lancet HIV. 2024 Jan;11(1):e42-e51. doi: 10.1016/S2352-3018(23)00265-5.ABSTRACTBACKGROUND: When caregivers live in remote settings characterised by extreme poverty, poor access to health services, and high rates of HIV/AIDS, their caregiving ability and children's development might be compromised. We aimed to test the effectiveness of a community-based child health and parenting intervention to improve child HIV testing, health, and development in rural Lesotho.METHODS: We implemented a matched cluster-randomised, controlled trial in the Mokhotlong district in northeastern Lesotho with 34 community clusters randomly assign...
Source: Rural Remote Health - December 23, 2023 Category: Rural Health Authors: Mark Tomlinson Marguerite Marlow Jackie Stewart Moroesi Makhetha Tholoana Sekotlo Sebuoeng Mohale Carl Lombard Lynne Murray Peter J Cooper Nathene Morley Stephan Rabie Sarah Gordon Amelia van der Merwe Gretchen Bachman Xanthe Hunt Lorraine Sherr Lucie Clu Source Type: research

A community-based child health and parenting intervention to improve child HIV testing, health, and development in rural Lesotho (Early Morning Star): a cluster-randomised, controlled trial
Lancet HIV. 2024 Jan;11(1):e42-e51. doi: 10.1016/S2352-3018(23)00265-5.ABSTRACTBACKGROUND: When caregivers live in remote settings characterised by extreme poverty, poor access to health services, and high rates of HIV/AIDS, their caregiving ability and children's development might be compromised. We aimed to test the effectiveness of a community-based child health and parenting intervention to improve child HIV testing, health, and development in rural Lesotho.METHODS: We implemented a matched cluster-randomised, controlled trial in the Mokhotlong district in northeastern Lesotho with 34 community clusters randomly assign...
Source: Rural Remote Health - December 23, 2023 Category: Rural Health Authors: Mark Tomlinson Marguerite Marlow Jackie Stewart Moroesi Makhetha Tholoana Sekotlo Sebuoeng Mohale Carl Lombard Lynne Murray Peter J Cooper Nathene Morley Stephan Rabie Sarah Gordon Amelia van der Merwe Gretchen Bachman Xanthe Hunt Lorraine Sherr Lucie Clu Source Type: research

Magnitude and Determinants of Virological Failure Among Patients > 15 Years on Anti-Retroviral Therapy in Rural Lesotho Between 2015 and 2019 – A Retrospective Cohort Study [Retraction]
(Source: Therapeutics and Clinical Risk Management)
Source: Therapeutics and Clinical Risk Management - December 22, 2023 Category: Drugs & Pharmacology Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Resilient Self-Talk in University Students Raised by Alcohol-Misusing Caregivers in Lesotho
Volume 42, Issue 1, January 2024, Page 45-61 . (Source: Alcoholism Treatment Quarterly)
Source: Alcoholism Treatment Quarterly - December 3, 2023 Category: Addiction Authors: Simbai MushongaGrey MagaizaCentre for Gender and African Studies (CGAS), University of the Free State, Bloemfontein, South Africa Source Type: research

Approaches for measuring cumulative childhood adversity: A study of youth from 5 sub-Saharan African countries
CONCLUSIONS: The challenges operationalizing CCA warrant continued research to ensure adversity type, severity, and context lead to validly assessing ACEs impact on child wellbeing.PMID:37996356 | DOI:10.1016/j.chiabu.2023.106542 (Source: Child Abuse and Neglect)
Source: Child Abuse and Neglect - November 23, 2023 Category: Child Development Authors: Leah K Gilbert Sarah Matthews Shanta R Dube Francis B Annor Source Type: research

Approaches for measuring cumulative childhood adversity: A study of youth from 5 sub-Saharan African countries
CONCLUSIONS: The challenges operationalizing CCA warrant continued research to ensure adversity type, severity, and context lead to validly assessing ACEs impact on child wellbeing.PMID:37996356 | DOI:10.1016/j.chiabu.2023.106542 (Source: Child Abuse and Neglect)
Source: Child Abuse and Neglect - November 23, 2023 Category: Child Development Authors: Leah K Gilbert Sarah Matthews Shanta R Dube Francis B Annor Source Type: research

Parental absence as an adverse childhood experience among young adults in sub-Saharan Africa
CONCLUSION: The observed association between parental absence and poor mental health suggests that this experience has significant adverse consequences and merits consideration as an ACE.PMID:37993366 | DOI:10.1016/j.chiabu.2023.106556 (Source: Child Abuse and Neglect)
Source: Child Abuse and Neglect - November 22, 2023 Category: Child Development Authors: Francis B Annor Ermias W Amene Liping Zhu Caroline Stamatakis Viani Picchetti Sarah Matthews Stephanie S Miedema Colvette Brown Viva C Thorsen Pedro Manuel Leah K Gilbert Caroline Kambona Rachel Coomer Joseph Trika Rashimisa Kamuingona Shanta R Dube Greta Source Type: research