A case of CD74 ‐ROS1‐positive lung adenocarcinoma diagnosed by next‐generation sequencing achieved long‐term survival with pemetrexed regimens
Patients with advanced NSCLC who achieve long-term survival should be assessed for the presence of a driver mutation via NGS testing. In patients showing good clinical response to PEM regimens, physicians should consider testing for ROS1/ALK rearrangement. AbstractPreviously, cytotoxic drugs were the only option for patients with non-small cell lung cancer (NSCLC) and the prognosis was poor. However, molecularly targeted therapies and immune checkpoint inhibitors represent a breakthrough in the treatment of advanced NSCLC and have improved survival rates. In addition, advances in next-generation sequencing (NGS) have revea...
Source: Thoracic Cancer - July 25, 2023 Category: Cancer & Oncology Authors: Satoshi Tanaka,
Nobuaki Yoshimura,
Ryo Asakawa,
Satoshi Tobita,
Moto Yaga,
Kiyonobu Ueno Tags: CASE REPORT Source Type: research
An extremely rare case of pulmonary epithelioid hemangioendothelioma
Histological features of EHE: Hematoxylin and eosin (H&E) indicated that the tumor tissue morphology is diverse, showing nodular growth, showing well-defined eosinophilic nodules, and transparent degeneration or coagulative necrosis similar to amyloidosis or chondroma can be seen in the center. There are many cells around the nodule, and the cell mass located in the mucilaginous chondroid matrix extends into the alveolar cavity, bronchioles, blood vessels, and lymphatic vessel. Part of the alveoli are filled with patches of tumor cells, presenting as papillary or glomerular like hyperplasia, with obvious hyaline degenerati...
Source: Thoracic Cancer - July 25, 2023 Category: Cancer & Oncology Authors: Xi Chen,
Yun Wang,
Guowei Che,
Cheng Shen Tags: CASE REPORT Source Type: research
Correction to “Clinical benefit of platinum doublet combination therapy in older adults with advanced non‐small cell lung cancer: A prospective multicenter study by the National Hospital Organization in Japan”
(Source: Thoracic Cancer)
Source: Thoracic Cancer - July 24, 2023 Category: Cancer & Oncology Tags: CORRECTION Source Type: research
Issue Information
(Source: Thoracic Cancer)
Source: Thoracic Cancer - July 24, 2023 Category: Cancer & Oncology Tags: ISSUE INFORMATION Source Type: research
Personalized cancer avatars for patients with thymic malignancies: A pilot study with circulating tumor cell ‐derived organoids
ConclusionThis study supports the potential of circulating tumor cell-derived organoids to inform personalized treatment for advanced thymic malignancies. Further validation of this proof of concept finding is ongoing. (Source: Thoracic Cancer)
Source: Thoracic Cancer - July 21, 2023 Category: Cancer & Oncology Authors: Yuan ‐Hung Wu,
Heng‐sheng Chao,
Chi‐Lu Chiang,
Yung‐Hung Luo,
Chao‐Hua Chiu,
Sang‐Hue Yen,
Chun‐Yu Liu,
Jeng‐Fong Chiou,
Thierry Burnouf,
Yin‐Ju Chen,
Peng‐Yuan Wang,
Tsu‐Yi Chao,
Shih‐Ming Hsu,
Long‐Sheng Lu Tags: ORIGINAL ARTICLE Source Type: research
