Issue Information
(Source: Thoracic Cancer)
Source: Thoracic Cancer - October 26, 2023 Category: Cancer & Oncology Tags: ISSUE INFORMATION Source Type: research
Computed tomography imaging and clinical characteristics of pulmonary ground ‐glass nodules ≤2 cm with micropapillary pattern
ConclusionmGGNs ≤2 cm with a micropapillary pattern have a higher risk of lymph node metastasis compared with SNs, and computed tomography (CT) imaging features can assist in their diagnosis. (Source: Thoracic Cancer)
Source: Thoracic Cancer - October 25, 2023 Category: Cancer & Oncology Authors: Chen ‐ran Guo,
Lin Xu,
Xiao Li,
Yi‐lin Fu,
Hui Wang,
Rui Han,
Geng‐sheng Li,
Zhen Feng,
Meng Li,
Wan‐gang Ren,
Zhong‐min Peng Tags: ORIGINAL ARTICLE Source Type: research
Safety and efficacy of amrubicin with primary prophylactic pegfilgrastim as second ‐line chemotherapy in patients with small cell lung cancer
ConclusionsAMR with P-PEG as second-line chemotherapy for SCLC reduced the incidence of FN at a maintained AMR dose intensity and was associated with favorable tumor responses and survival outcomes. P-PEG should be considered for patients treated with AMR for SCLC including refractory relapsed SCLC. (Source: Thoracic Cancer)
Source: Thoracic Cancer - October 24, 2023 Category: Cancer & Oncology Authors: Motoki Sekikawa,
Haruyasu Murakami,
Meiko Morita,
Kosei Doshita,
Keita Miura,
Hiroaki Kodama,
Noboru Morikawa,
Yuko Iida,
Nobuaki Mamesaya,
Haruki Kobayashi,
Ryo Ko,
Kazushige Wakuda,
Akira Ono,
Hirotsugu Kenmotsu,
Tateaki Naito,
Hirofumi C Tags: ORIGINAL ARTICLE Source Type: research
Circ_0102231 inactivates the PI3K/AKT signaling pathway by regulating the miR ‐635/NOVA2 pathway to promote the progression of non‐small cell lung cancer
ConclusionCirc_0102231 increased the expression of NOVA2 by interacting with miR-635 to promote the malignant progression of NSCLC. (Source: Thoracic Cancer)
Source: Thoracic Cancer - October 21, 2023 Category: Cancer & Oncology Authors: Jianhong Liu,
Qiong Yu,
Xu Yang Tags: ORIGINAL ARTICLE Source Type: research
Clinical characteristics and treatment outcomes of HER2 mutation and HER2 fusion in 22 patients with advanced breast cancer
ConclusionOur data demonstrated the clinical benefit of anti-HER2 treatment in Chinese breast cancer patients harboring HER2 mutation and/or HER2 fusion. The value of immunotherapy and treatment selection among individual HER2 variants needs further study. (Source: Thoracic Cancer)
Source: Thoracic Cancer - October 21, 2023 Category: Cancer & Oncology Authors: Yuxin Mu,
Yanchun Meng,
Yiqun Du,
Xiaojun Liu,
Jian Zhang Tags: ORIGINAL ARTICLE Source Type: research
Three ‐dimensional lung reconstructions for the localization of lung nodules to be resected during surgery
ConclusionsOur 3D lung reconstruction model for use in the operating room may be an additional tool for thoracic surgeons to guide the detection of small and deep nodules during thoracoscopy. It is a noninvasive and cost saving procedure and may be widely used. (Source: Thoracic Cancer)
Source: Thoracic Cancer - October 20, 2023 Category: Cancer & Oncology Authors: Giovanni Natale,
Beatrice Leonardi,
Gaetana Messina,
Grazia Bergameo,
Vincenzo Di Filippo,
Giulia Chisari,
Gabriele Raciti,
Sofia Paola Lombardo,
Rosa Mirra,
Francesca Capasso,
Francesco Leone,
Davide Gerardo Pica,
Alfonso Fiorelli Tags: ORIGINAL ARTICLE Source Type: research
Effect of ultrasound ‐guided thoracic paravertebral block on perioperative analgesia in elderly patients undergoing video‐assisted thoracic lobectomy in China: An interventional clinical randomized controlled trial
ConclusionUG-TPVB is an effective and safe perioperative analgesia method for elderly VATL patients. Its application improves the quality of life and prognosis of elderly VATL patients. (Source: Thoracic Cancer)
Source: Thoracic Cancer - October 19, 2023 Category: Cancer & Oncology Authors: Chanjuan Gong,
Rong Ma,
Bing Li,
Li Wen,
Zhengnian Ding Tags: ORIGINAL ARTICLE Source Type: research
Dosimetric comparison of five different radiotherapy treatment planning approaches for locally advanced non ‐small cell lung cancer with sequential plan changes
ConclusionThe IMRT/VMAT hybrid technique for LA-NSCLC patients improved target CI and reduced lung doses. Furthermore, if IMRT was not available initially, starting with 3DCRT might be beneficial as demonstrated in the bVMAT procedure of this study. (Source: Thoracic Cancer)
Source: Thoracic Cancer - October 17, 2023 Category: Cancer & Oncology Authors: Masahide Saito,
Takafumi Komiyama,
Kan Marino,
Shinichi Aoki,
Tomoko Akita,
Masaki Matsuda,
Naoki Sano,
Hidekazu Suzuki,
Ueda Koji,
Hikaru Nemoto,
Hiroshi Onishi Tags: ORIGINAL ARTICLE Source Type: research
First case report of erlotinib plus ramucirumab treatment for lung carcinosarcoma with EGFR L858R mutation
In this study, we report the case of a 73-year-old female patient diagnosed with postoperative recurrence of lung carcinosarcoma. The resected tumor was diagnosed as lung carcinosarcoma, and genetic testing revealed the presence of the epidermal growth factor receptor (EGFR) exon21 L858R. Approximately 2 years postoperatively, the tumor recurred and the patient was treated with erlotinib plus ramucirumab, which were effective in controlling metastatic disease. Erlotinib plus ramucirumab is therefore a treatment option forEGFR mutation-positive lung carcinosarcoma. (Source: Thoracic Cancer)
Source: Thoracic Cancer - October 15, 2023 Category: Cancer & Oncology Authors: Naoya Ishibashi,
Toshiharu Tabata,
Ryo Nonomura,
Yutaka Oshima,
Takanobu Sasaki,
Hideki Mitomo,
Takafumi Sugawara,
Motoyasu Sagawa Tags: CASE REPORT Source Type: research
Regulation of ferroptosis ‐related genes in CD8+ NKT cells and classical monocytes may affect the immunotherapy response after combined treatment in triple negative breast cancer
ConclusionOverall, the composition of the tumor microenvironment affects the immunotherapy response of patients, and DUSP1 may be a potential target for overcoming drug resistance. (Source: Thoracic Cancer)
Source: Thoracic Cancer - October 14, 2023 Category: Cancer & Oncology Authors: Zheming Liu,
Songjiang He,
Zhou Huang,
Jiahui Liu,
Yiping Gong,
Yi Yao,
Xue Zhang Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
(Source: Thoracic Cancer)
Source: Thoracic Cancer - October 12, 2023 Category: Cancer & Oncology Tags: ISSUE INFORMATION Source Type: research
Circ_MACF1 targets miR ‐421 to upregulate FMO2 to suppress paclitaxel resistance and malignant cellular behaviors in lung adenocarcinoma
ConclusionThese findings elucidated that circ_MACF1 inhibited PTX resistance by absorbing miR-421 to upregulate FMO2 in LADC. (Source: Thoracic Cancer)
Source: Thoracic Cancer - October 11, 2023 Category: Cancer & Oncology Authors: Xiaoting Qian,
Chunhua Chen,
Sanxiang Tong,
Jun Zhang Tags: ORIGINAL ARTICLE Source Type: research
Evaluation of pain levels treated by the distal end of the hook ‐wire positioning needle: A randomized controlled study
ConclusionsWe found both approaches for handling the hook-wire extending outside the chest to be safe and effective. However, cutting off the hook-wire extending outside the chest is associated with lesser pain. Moreover, pain severity does not worsen with time after localization. (Source: Thoracic Cancer)
Source: Thoracic Cancer - October 10, 2023 Category: Cancer & Oncology Authors: Yong Ge,
Jiajian Pan,
Teng Sun,
Shoujie Feng,
Cheng Zhang,
Hao Zhang Tags: ORIGINAL ARTICLE Source Type: research
Epidemiological characteristics and therapeutic advances of EGFR exon 20 insertion mutations in non ‐small cell lung cancer
Epidermal growth factor receptor (EGFR) exon 20 insertions (EGFRex20ins), the third most prevalentEGFR mutation in non-small cell lung (NSCLC) cancer, pose a significant clinical challenge due to resistance to conventional treatments. Recent approvals of mobocertinib and amivantamab offer promising therapeutic options. This review summarizes key epidemiological and therapeutic insights, paving the way for improved clinical management of NSCLC patients with EGFRex20ins. AbstractThe third most prevalent type of epidermal growth factor receptor (EGFR) mutation, EGFR exon 20 insertions (EGFRex20ins), involves 2% –12% of all ...
Source: Thoracic Cancer - October 6, 2023 Category: Cancer & Oncology Authors: Binyang Pan,
Jiaqi Liang,
Haochun Shi,
Kungeng Rao,
Weigang Guo,
Cheng Zhan Tags: REVIEW Source Type: research
Identification of a coagulation ‐related signature correlated with immune infiltration and their prognostic implications in lung adenocarcinoma
ConclusionsOur study revealed a significant correlation between CRRS and immune infiltration. CRRS could serve as a promising tool to improve the clinical outcomes for individual LUAD patients. (Source: Thoracic Cancer)
Source: Thoracic Cancer - October 5, 2023 Category: Cancer & Oncology Authors: Siqian Yang,
Shiqi Chen,
Yue Zhao,
Tao Wu,
Yuquan Wang,
Tingting Li,
Liwan Fu,
Ting Ye,
Yue ‐Qing Hu,
Haiquan Chen Tags: ORIGINAL ARTICLE Source Type: research
