Amplitude of low-frequency fluctuation after a single-trigger pain in patients with classical trigeminal neuralgia
ConclusionsThe sALFF and dALFF values changed differently in multiple brain regions in triggering-5 s and triggering-30 min of CTN patients after a single trigger of pain, and dALFF is complementary to sALFF. The results might help explore the therapeutic targets for relieving pain and improving the quality of life of patients with CTN. (Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - September 8, 2022 Category: Neurology Source Type: research
Correction: Applying a biopsychosocial model to migraine: rationale and clinical implications
(Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - September 7, 2022 Category: Neurology Source Type: research
Quantity changes in acute headache medication use among patients with chronic migraine treated with eptinezumab: subanalysis of the PROMISE-2 study
ConclusionsIn this post hoc analysis, eptinezumab use in patients with CM was associated with greater decreases in days with headache with AHM overall and with triptans in particular. The magnitude of effect was greater in the subgroup of CM patients with MOH and ≥ 50% response.Trial registrationClinicalTrials.gov Identifier:NCT02974153.Graphical abstractEptinezumab reduces headache frequency and acute medication use in patients with chronic migraine. (Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - September 6, 2022 Category: Neurology Source Type: research
Long term evaluation of a multidisciplinary trigeminal neuralgia service
ConclusionAn MDT clinic offers an opportunity for shared decision making with patients deciding on their personal care pathway which is valued by patients. Not all patients opt for surgery, and some continue to attend a multidisciplinary follow up program. Providing a full range of services including psychological support, improves outcomes. (Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - September 3, 2022 Category: Neurology Source Type: research
Disease- and headache-specific microRNA signatures and their predicted mRNA targets in peripheral blood mononuclear cells in migraineurs: role of inflammatory signalling and oxidative stress
ConclusionsWe provide here the first evidence for disease- and headache-specific miRNA signatures in the PBMC of migraineurs, which might help to identify novel targets for both prophylaxis and attack therapy. (Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - September 2, 2022 Category: Neurology Source Type: research
