The variability of diagnosed migraine epidemiology amongst different municipalities in southern Israel
ConclusionsHigh variability in the prevalence of diagnosed migraine suggests underdiagnosis. Resources for awareness and educational programs should be directed to low diagnosed prevalence communities.Graphical Abstract (Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - March 13, 2023 Category: Neurology Source Type: research
Cross-sectional, hospital-based analysis of headache types using ICHD-3 criteria in the Middle East, Asia, and Africa: the Head-MENAA study
ConclusionsThe study showed that migraine is still the most common motive for admissions to NC in different regions. Furthermore, MOH, an avoidable disorder, is the most common secondary headache type and appears to be a significant problem in all regions. Remarkably, pain perception differs between regions, and pain intensity is lower in Africa than in other regions. (Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - March 13, 2023 Category: Neurology Source Type: research
Predicting response to CGRP-monoclonal antibodies in patients with migraine in Japan: a single-centre retrospective observational study
ConclusionsPatients with migraine who are older, with fewer prior treatment failures and no past history of immuno-rheumatologic disease, may respond well to CGRPmAbs. (Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - March 9, 2023 Category: Neurology Source Type: research
The HARDSHIP databases: a forthcoming free good from the Global Campaign against Headache
AbstractIn order to pursue its purpose of reducing the global burden of headache, the Global Campaign against Headache has gathered data on headache-attributed burden from countries worldwide. These data, from the individual participants in adult population-based studies and child and adolescent schools-based studies, are being collated in two databases, which will be powerful resources for research and teaching and rich information sources for health policy.Here we briefly describe the structure and content of these databases, and announce the intention to make them available in due course as a free good. (Source: The Jou...
Source: The Journal of Headache and Pain - March 6, 2023 Category: Neurology Source Type: research
Correction: Investigation of cortical thickness and volume during spontaneous attacks of migraine without aura: a 3-Tesla MRI study
(Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - March 6, 2023 Category: Neurology Source Type: research
Should migraine without aura be further divided? A study of 1444 female patients with migraine without aura
This study provided a basis for further dividing MWA. Genetic research should be conducted and treatment should be prescribed accordingly because the underlying pathogenesis may be different. (Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - March 1, 2023 Category: Neurology Source Type: research
The applicability research of the diagnostic criteria for 10.2 Heamodialysis-related headache in the international classification of headache disorders-3rd edition
ConclusionsThe diagnostic criteria for 10.2 HDH in ICHD-3 may miss several HAH. Therefore, ICHD-3 should be revised according to the literature and further studies. (Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - February 28, 2023 Category: Neurology Source Type: research
Clinical evaluation of super-responders vs. non-responders to CGRP(-receptor) monoclonal antibodies: a real-world experience
ConclusionSeveral clinical parameters differ between SR and NR to prophylactic CGRP(-R) mAbs. A thorough clinical evaluation prior to treatment initiation might help to achieve a more personalized management in patients with migraine. (Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - February 27, 2023 Category: Neurology Source Type: research
Characterizing healthcare utilization patterns in a Danish population with headache: results from the nationwide headache in Denmark (HINDER) panel
ConclusionsOur findings are indicative of inadequate delivery of headache care in a country that provides free and universal coverage for all its residents. The implications are twofold. First, it is not sufficient merely to make services available: public education and increased awareness are necessary to encourage uptake by those who would benefit. Second, educational interventions in both pre- and postgraduate settings are necessary, but a prerequisite for these is a resetting of policy priorities, properly to reflect the very high population ill-health burden of headache. (Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - February 24, 2023 Category: Neurology Source Type: research
White matter hyperintensities and cerebral microbleeds in persistent post-traumatic headache attributed to mild traumatic brain injury: a magnetic resonance imaging study
ConclusionsWMHs and CMBs were not more prevalent in people with persistent post-traumatic headache than observed in healthy controls. Future studies should focus on other MRI techniques to identify radiologic biomarkers of post-traumatic headache. (Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - February 24, 2023 Category: Neurology Source Type: research
Alterations in regional homogeneity and multiple frequency amplitudes of low-frequency fluctuation in patients with new daily persistent headache: a resting-state functional magnetic resonance imaging study
ConclusionsPatients with NDPH may have abnormal activation of the visual system. Abnormal visual activation may occur mainly in higher frequency band of the classical band. No sex differences in brain activity were found in patients with NDPH. (Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - February 23, 2023 Category: Neurology Source Type: research
Alteration of the cortical morphology in classical trigeminal neuralgia: voxel-, deformation-, and surface-based analysis
ConclusionsThe gray matter volume and cortical morphology of pain-related brain regions were correlated with clinical and trigeminal nerve parameters. voxel-based morphometry, deformation-based morphometry, and surface-based morphometry complemented each other in analyzing the brain structures of patients with classical trigeminal neuralgia and provided a basis for studying the pathophysiology of classical trigeminal neuralgia.Graphical Abstract (Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - February 21, 2023 Category: Neurology Source Type: research
Genetics of migraine: where are we now?
AbstractMigraine is a complex brain disorder explained by the interaction of genetic and environmental factors. In monogenic migraines, including familial hemiplegic migraine and migraine with aura associated with hereditary small-vessel disorders, the identified genes code for proteins expressed in neurons, glial cells, or vessels, all of which increase susceptibility to cortical spreading depression. The study of monogenic migraines has shown that the neurovascular unit plays a prominent role in migraine. Genome-wide association studies have identified numerous susceptibility variants that each result in only a small inc...
Source: The Journal of Headache and Pain - February 20, 2023 Category: Neurology Source Type: research
Spatio-temporal dynamics of resting-state brain networks are associated with migraine disability
ConclusionsOur study confirmed the notion that altered spatio-temporal dynamics exist in migraine patients during resting-state. And the temporal dynamics, the spatial changes and the clinical traits such as migraine disability interact with each other. The spatio-temporal dynamics obtained from EEG microstate and fMRI FC analyses may be potential biomarkers for migraine and with a huge potential to change future clinical practice in migraine. (Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - February 20, 2023 Category: Neurology Source Type: research
A study of differential microRNA expression profile in migraine: the microMIG exploratory study
ConclusionsA 3-miRNA (miR-342-3p, miR-532-3p and miR-758-5p) novel signature has been found differentially expressed between controls and patients with migraine. Enrichment analysis showed that these pathways are closely associated with known migraine pathophysiology, which could lead to the first reliable epigenetic biomarker set. Further studies should be performed to validate these findings in a larger and more heterogeneous sample. (Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - February 17, 2023 Category: Neurology Source Type: research
