The American Journal of Chinese Medicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Red Yeast Rice and Statin Therapy in Patients with Hypercholesterolemia and the Comorbidities: A Retrospective Cohort Study on Lipid-Lowering Effects and Cardiovascular Outcomes
In conclusion, both RYR and statins effectively lower blood lipid levels and mitigate related complications. Combining these therapies may lead to fewer ER visits, reduced stroke frequency, and fewer MI hospitalizations in hypertensive and kidney disease patients, and they decreased all-cause mortality in the kidney disease population. Further research on combined therapy is warranted.PMID:38480501 | DOI:10.1142/S0192415X24500174 (Source: The American Journal of Chinese Medicine)
Source: The American Journal of Chinese Medicine - March 14, 2024 Category: Complementary Medicine Authors: Tun-Pin Hsueh Wan-Ling Lin Wen-Long Hu Yu-Chiang Hung Source Type: research

Curcumin Analog L48H37 Induces Apoptosis in Human Oral Cancer Cells by Activating Caspase Cascades and Downregulating the Inhibitor of Apoptosis Proteins through JNK/p38 Signaling
Am J Chin Med. 2024 Mar 14:1-17. doi: 10.1142/S0192415X24500241. Online ahead of print.ABSTRACTL48H37 is a synthetic curcumin analog that has anticancer potentials. Here, we further explored the anticancer effect of L48H37 on oral cancer cells and its mechanistic acts. Cell cycle distribution was assessed using flow cytometric analysis. Apoptosis was elucidated by staining with PI/Annexin V and activation of the caspase cascade. Cellular signaling was explored using apoptotic protein profiling, Western blotting, and specific inhibitors. Our findings showed that L48H37 significantly reduced the cell viability of SCC-9 and H...
Source: The American Journal of Chinese Medicine - March 14, 2024 Category: Complementary Medicine Authors: Chun-Wen Su Shao-Hsuan Kao Yi-Tzu Chen Yi-Hsien Hsieh Wei-En Yang Meng-Ying Tsai Chiao-Wen Lin Shun-Fa Yang Source Type: research

Mechanism of Acupuncture in Treating Obesity: Advances and Prospects
Am J Chin Med. 2024;52(1):1-33. doi: 10.1142/S0192415X24500010. Epub 2024 Feb 8.ABSTRACTObesity is a common metabolic syndrome that causes a significant burden on individuals and society. Conventional therapies include lifestyle interventions, bariatric surgery, and pharmacological therapies, which are not effective and have a high risk of adverse events. Acupuncture is an effective alternative for obesity, it modulates the hypothalamus, sympathetic activity and parasympathetic activity, obesity-related hormones (leptin, ghrelin, insulin, and CCK), the brain-gut axis, inflammatory status, adipose tissue browning, muscle bl...
Source: The American Journal of Chinese Medicine - February 14, 2024 Category: Complementary Medicine Authors: Mi-Na Wang Miao-Xin Zhai Yi-Tong Wang Qiu-Fu Dai Lu Liu Luo-Peng Zhao Qiu-Yu Xia Shen Li Bin Li Source Type: research

Berberine Metabolites Stimulate GLP-1 Secretion by Alleviating Oxidative Stress and Mitochondrial Dysfunction
Am J Chin Med. 2024;52(1):253-274. doi: 10.1142/S0192415X24500113. Epub 2024 Feb 8.ABSTRACTBerberine (BBR) is a principal component of Rhizoma coptidis known for its therapeutic potential in treating diseases such as type 2 diabetes mellitus (T2DM) and obesity. Despite the trace levels of BBR in plasma, it's believed that its metabolites play a pivotal role in its biological activities. While BBR is recognized to promote GLP-1 production in intestinal L cells, the cytoprotective effects of its metabolites on these cells are yet to be explored. The present study investigates the effects of BBR metabolites on GLP-1 secretion...
Source: The American Journal of Chinese Medicine - February 14, 2024 Category: Complementary Medicine Authors: Wei-Li Yang Chen-Yang Zhang Wen-Yi Ji Li-Li Zhao Fang-Yuan Yang Lin Zhang Xi Cao Source Type: research

< em > Taraxacum < /em > : A Review of Ethnopharmacology, Phytochemistry and Pharmacological Activity
Am J Chin Med. 2024;52(1):183-215. doi: 10.1142/S0192415X24500083. Epub 2024 Feb 8.ABSTRACTTaraxacum refers to the genus Taraxacum, which has a long history of use as a medicinal plant and is widely distributed around the world. There are over 2500 species in the genus Taraxacum recorded as medicinal plants in China, Central Asia, Europe, and the Americas. It has traditionally been used for detoxification, diuresis, liver protection, the treatment of various inflammations, antimicrobial properties, and so on. We used the most typically reported Taraxacum officinale as an example and assembled its chemical makeup, including...
Source: The American Journal of Chinese Medicine - February 14, 2024 Category: Complementary Medicine Authors: Fusheng Hao Xinxin Deng Xin Yu Wen Wang Wei Yan Xi Zhao Xiaofei Wang Changcai Bai Zhizhong Wang Lu Han Source Type: research

The Landscape of Gut Microbiota and Its Metabolites: A Key to Understanding the Pathophysiology of Pattern in Chinese Medicine
This study aims to provide an overview of existing research findings and gaps for the pathophysiological study of LSSD from the gut microbiota perspective in order to understand the relationship between the CM pattern and disease progression and to optimize CM-based diagnosis, prevention, and therapy.PMID:38351704 | DOI:10.1142/S0192415X24500046 (Source: The American Journal of Chinese Medicine)
Source: The American Journal of Chinese Medicine - February 14, 2024 Category: Complementary Medicine Authors: Zhaozhou Zhang Liqing Du Qiuchen Ji Hao Liu Zhenxing Ren Guang Ji Zhao-Xiang Bian Ling Zhao Source Type: research

Efficacy and Mechanisms of Natural Products as Therapeutic Interventions for Chronic Respiratory Diseases
Am J Chin Med. 2024;52(1):57-88. doi: 10.1142/S0192415X24500034. Epub 2024 Feb 14.ABSTRACTChronic respiratory diseases are long-term conditions affecting the airways and other lung components that are characterized by a high prevalence, disability rate, and mortality rate. Further optimization of their treatment is required. Natural products, primarily extracted from organisms, possess specific molecular and structural formulas as well as distinct chemical and physical properties. These characteristics grant them the advantages of safety, gentleness, accessibility, and minimal side effects. The numerous advances in the use...
Source: The American Journal of Chinese Medicine - February 14, 2024 Category: Complementary Medicine Authors: Fanli Jin Pengbei Fan Yuanyuan Wu Qingzhen Yang Jiansheng Li Han Liu Source Type: research

Phytochemistry of Red Ginseng, a Steam-Processed < em > Panax ginseng < /em >
In conclusion, to ensure the safe and effective use of red ginseng, phytochemical and analytical studies of its constituents are necessary and even crucial.PMID:38353635 | DOI:10.1142/S0192415X24500022 (Source: The American Journal of Chinese Medicine)
Source: The American Journal of Chinese Medicine - February 14, 2024 Category: Complementary Medicine Authors: Chong-Zhi Wang Chun-Feng Zhang Qi-Hui Zhang Chun-Su Yuan Source Type: research