β-Escin: An Updated Review of Its Analysis, Pharmacology, Pharmacokinetics, and Toxicity
Am J Chin Med. 2023 Oct 20:1-26. doi: 10.1142/S0192415X23500908. Online ahead of print.ABSTRACT[Formula: see text]-Escin is an oleanane-type pentacyclic triterpenoid saponin extracted from the seeds of Aesculus hippocastanum (AH), which is more widely distributed. [Formula: see text]-Escin sodium has been approved by the American FDA for clinical usage. This paper is intended to summarize an updated and comprehensive review of the pharmacological activities, pharmacokinetic properties, toxicity, and analytical methods of [Formula: see text]-escin. Studies have shown that [Formula: see text]-escin has significant antitumor,...
Source: The American Journal of Chinese Medicine - October 22, 2023 Category: Complementary Medicine Authors: Yunyu Wang Xiuwei Han Xinhuan Wan Fengjv Niu Changzheng Zhou Source Type: research

Pachymic Acid Prevents Hemorrhagic Shock-Induced Cardiac Injury by Suppressing M1 Macrophage Polarization and NF-[Formula: see text]B Signaling Pathway
In conclusion, PA-pretreatment ameliorates HS-induced cardiac injury, potentially through its inhibition of the NF-[Formula: see text]B pathway. Therefore, PA treatment holds promise as a strategy for mitigating cardiac damage in HS.PMID:37865871 | DOI:10.1142/S0192415X23500921 (Source: The American Journal of Chinese Medicine)
Source: The American Journal of Chinese Medicine - October 22, 2023 Category: Complementary Medicine Authors: Zhenfeng Liu Wuming Zhou Qingyang Liu Zhirong Huan Qiubo Wang Xin Ge Source Type: research

β-Escin: An Updated Review of Its Analysis, Pharmacology, Pharmacokinetics, and Toxicity
Am J Chin Med. 2023 Oct 20:1-26. doi: 10.1142/S0192415X23500908. Online ahead of print.ABSTRACT[Formula: see text]-Escin is an oleanane-type pentacyclic triterpenoid saponin extracted from the seeds of Aesculus hippocastanum (AH), which is more widely distributed. [Formula: see text]-Escin sodium has been approved by the American FDA for clinical usage. This paper is intended to summarize an updated and comprehensive review of the pharmacological activities, pharmacokinetic properties, toxicity, and analytical methods of [Formula: see text]-escin. Studies have shown that [Formula: see text]-escin has significant antitumor,...
Source: The American Journal of Chinese Medicine - October 22, 2023 Category: Complementary Medicine Authors: Yunyu Wang Xiuwei Han Xinhuan Wan Fengjv Niu Changzheng Zhou Source Type: research

Pachymic Acid Prevents Hemorrhagic Shock-Induced Cardiac Injury by Suppressing M1 Macrophage Polarization and NF-[Formula: see text]B Signaling Pathway
In conclusion, PA-pretreatment ameliorates HS-induced cardiac injury, potentially through its inhibition of the NF-[Formula: see text]B pathway. Therefore, PA treatment holds promise as a strategy for mitigating cardiac damage in HS.PMID:37865871 | DOI:10.1142/S0192415X23500921 (Source: The American Journal of Chinese Medicine)
Source: The American Journal of Chinese Medicine - October 22, 2023 Category: Complementary Medicine Authors: Zhenfeng Liu Wuming Zhou Qingyang Liu Zhirong Huan Qiubo Wang Xin Ge Source Type: research

Regulatory Effects of Quercetin on Bone Homeostasis: Research Updates and Future Perspectives
Am J Chin Med. 2023 Oct 9:1-18. doi: 10.1142/S0192415X23500891. Online ahead of print.ABSTRACTThe imbalance of bone homeostasis has become a major public medical problem amid the background of an aging population, which is closely related to the occurrence of osteoporosis, osteoarthritis, and fractures. Presently, most drugs used in the clinical treatment of bone homeostasis imbalance are bisphosphonates, calcitonin, estrogen receptor modulators, and biological agents that inhibit bone resorption or parathyroid hormone analogs that promote bone formation. However, there are many adverse reactions. Therefore, it is necessar...
Source: The American Journal of Chinese Medicine - October 10, 2023 Category: Complementary Medicine Authors: Yujiang Xi Jiayan Shen Xiahuang Li Yi Bao Ting Zhao Bo Li Xiaoyu Zhang Jian Wang Yanyuan Bao Jiamei Gao Zhaohu Xie Qi Wang Qiu Luo Hongling Shi Zhaofu Li Dongdong Qin Source Type: research

Regulatory Effects of Quercetin on Bone Homeostasis: Research Updates and Future Perspectives
Am J Chin Med. 2023 Oct 9:1-18. doi: 10.1142/S0192415X23500891. Online ahead of print.ABSTRACTThe imbalance of bone homeostasis has become a major public medical problem amid the background of an aging population, which is closely related to the occurrence of osteoporosis, osteoarthritis, and fractures. Presently, most drugs used in the clinical treatment of bone homeostasis imbalance are bisphosphonates, calcitonin, estrogen receptor modulators, and biological agents that inhibit bone resorption or parathyroid hormone analogs that promote bone formation. However, there are many adverse reactions. Therefore, it is necessar...
Source: The American Journal of Chinese Medicine - October 10, 2023 Category: Complementary Medicine Authors: Yujiang Xi Jiayan Shen Xiahuang Li Yi Bao Ting Zhao Bo Li Xiaoyu Zhang Jian Wang Yanyuan Bao Jiamei Gao Zhaohu Xie Qi Wang Qiu Luo Hongling Shi Zhaofu Li Dongdong Qin Source Type: research

Regulatory Effects of Quercetin on Bone Homeostasis: Research Updates and Future Perspectives
Am J Chin Med. 2023 Oct 9:1-18. doi: 10.1142/S0192415X23500891. Online ahead of print.ABSTRACTThe imbalance of bone homeostasis has become a major public medical problem amid the background of an aging population, which is closely related to the occurrence of osteoporosis, osteoarthritis, and fractures. Presently, most drugs used in the clinical treatment of bone homeostasis imbalance are bisphosphonates, calcitonin, estrogen receptor modulators, and biological agents that inhibit bone resorption or parathyroid hormone analogs that promote bone formation. However, there are many adverse reactions. Therefore, it is necessar...
Source: The American Journal of Chinese Medicine - October 10, 2023 Category: Complementary Medicine Authors: Yujiang Xi Jiayan Shen Xiahuang Li Yi Bao Ting Zhao Bo Li Xiaoyu Zhang Jian Wang Yanyuan Bao Jiamei Gao Zhaohu Xie Qi Wang Qiu Luo Hongling Shi Zhaofu Li Dongdong Qin Source Type: research

Regulatory Effects of Quercetin on Bone Homeostasis: Research Updates and Future Perspectives
Am J Chin Med. 2023 Oct 9:1-18. doi: 10.1142/S0192415X23500891. Online ahead of print.ABSTRACTThe imbalance of bone homeostasis has become a major public medical problem amid the background of an aging population, which is closely related to the occurrence of osteoporosis, osteoarthritis, and fractures. Presently, most drugs used in the clinical treatment of bone homeostasis imbalance are bisphosphonates, calcitonin, estrogen receptor modulators, and biological agents that inhibit bone resorption or parathyroid hormone analogs that promote bone formation. However, there are many adverse reactions. Therefore, it is necessar...
Source: The American Journal of Chinese Medicine - October 10, 2023 Category: Complementary Medicine Authors: Yujiang Xi Jiayan Shen Xiahuang Li Yi Bao Ting Zhao Bo Li Xiaoyu Zhang Jian Wang Yanyuan Bao Jiamei Gao Zhaohu Xie Qi Wang Qiu Luo Hongling Shi Zhaofu Li Dongdong Qin Source Type: research

Regulatory Effects of Quercetin on Bone Homeostasis: Research Updates and Future Perspectives
Am J Chin Med. 2023 Oct 9:1-18. doi: 10.1142/S0192415X23500891. Online ahead of print.ABSTRACTThe imbalance of bone homeostasis has become a major public medical problem amid the background of an aging population, which is closely related to the occurrence of osteoporosis, osteoarthritis, and fractures. Presently, most drugs used in the clinical treatment of bone homeostasis imbalance are bisphosphonates, calcitonin, estrogen receptor modulators, and biological agents that inhibit bone resorption or parathyroid hormone analogs that promote bone formation. However, there are many adverse reactions. Therefore, it is necessar...
Source: The American Journal of Chinese Medicine - October 10, 2023 Category: Complementary Medicine Authors: Yujiang Xi Jiayan Shen Xiahuang Li Yi Bao Ting Zhao Bo Li Xiaoyu Zhang Jian Wang Yanyuan Bao Jiamei Gao Zhaohu Xie Qi Wang Qiu Luo Hongling Shi Zhaofu Li Dongdong Qin Source Type: research

Regulatory Effects of Quercetin on Bone Homeostasis: Research Updates and Future Perspectives
Am J Chin Med. 2023 Oct 9:1-18. doi: 10.1142/S0192415X23500891. Online ahead of print.ABSTRACTThe imbalance of bone homeostasis has become a major public medical problem amid the background of an aging population, which is closely related to the occurrence of osteoporosis, osteoarthritis, and fractures. Presently, most drugs used in the clinical treatment of bone homeostasis imbalance are bisphosphonates, calcitonin, estrogen receptor modulators, and biological agents that inhibit bone resorption or parathyroid hormone analogs that promote bone formation. However, there are many adverse reactions. Therefore, it is necessar...
Source: The American Journal of Chinese Medicine - October 10, 2023 Category: Complementary Medicine Authors: Yujiang Xi Jiayan Shen Xiahuang Li Yi Bao Ting Zhao Bo Li Xiaoyu Zhang Jian Wang Yanyuan Bao Jiamei Gao Zhaohu Xie Qi Wang Qiu Luo Hongling Shi Zhaofu Li Dongdong Qin Source Type: research

Regulatory Effects of Quercetin on Bone Homeostasis: Research Updates and Future Perspectives
Am J Chin Med. 2023 Oct 9:1-18. doi: 10.1142/S0192415X23500891. Online ahead of print.ABSTRACTThe imbalance of bone homeostasis has become a major public medical problem amid the background of an aging population, which is closely related to the occurrence of osteoporosis, osteoarthritis, and fractures. Presently, most drugs used in the clinical treatment of bone homeostasis imbalance are bisphosphonates, calcitonin, estrogen receptor modulators, and biological agents that inhibit bone resorption or parathyroid hormone analogs that promote bone formation. However, there are many adverse reactions. Therefore, it is necessar...
Source: The American Journal of Chinese Medicine - October 10, 2023 Category: Complementary Medicine Authors: Yujiang Xi Jiayan Shen Xiahuang Li Yi Bao Ting Zhao Bo Li Xiaoyu Zhang Jian Wang Yanyuan Bao Jiamei Gao Zhaohu Xie Qi Wang Qiu Luo Hongling Shi Zhaofu Li Dongdong Qin Source Type: research

Regulatory Effects of Quercetin on Bone Homeostasis: Research Updates and Future Perspectives
Am J Chin Med. 2023 Oct 9:1-18. doi: 10.1142/S0192415X23500891. Online ahead of print.ABSTRACTThe imbalance of bone homeostasis has become a major public medical problem amid the background of an aging population, which is closely related to the occurrence of osteoporosis, osteoarthritis, and fractures. Presently, most drugs used in the clinical treatment of bone homeostasis imbalance are bisphosphonates, calcitonin, estrogen receptor modulators, and biological agents that inhibit bone resorption or parathyroid hormone analogs that promote bone formation. However, there are many adverse reactions. Therefore, it is necessar...
Source: The American Journal of Chinese Medicine - October 10, 2023 Category: Complementary Medicine Authors: Yujiang Xi Jiayan Shen Xiahuang Li Yi Bao Ting Zhao Bo Li Xiaoyu Zhang Jian Wang Yanyuan Bao Jiamei Gao Zhaohu Xie Qi Wang Qiu Luo Hongling Shi Zhaofu Li Dongdong Qin Source Type: research

Regulatory Effects of Quercetin on Bone Homeostasis: Research Updates and Future Perspectives
Am J Chin Med. 2023 Oct 9:1-18. doi: 10.1142/S0192415X23500891. Online ahead of print.ABSTRACTThe imbalance of bone homeostasis has become a major public medical problem amid the background of an aging population, which is closely related to the occurrence of osteoporosis, osteoarthritis, and fractures. Presently, most drugs used in the clinical treatment of bone homeostasis imbalance are bisphosphonates, calcitonin, estrogen receptor modulators, and biological agents that inhibit bone resorption or parathyroid hormone analogs that promote bone formation. However, there are many adverse reactions. Therefore, it is necessar...
Source: The American Journal of Chinese Medicine - October 10, 2023 Category: Complementary Medicine Authors: Yujiang Xi Jiayan Shen Xiahuang Li Yi Bao Ting Zhao Bo Li Xiaoyu Zhang Jian Wang Yanyuan Bao Jiamei Gao Zhaohu Xie Qi Wang Qiu Luo Hongling Shi Zhaofu Li Dongdong Qin Source Type: research

Research Progress and New Perspectives of Anticancer Effects of Emodin
In conclusion, emodin represents a promising natural compound with potent anticancer properties, and its potential as a therapeutic agent for cancer treatment warrants further investigation. This review provides a comprehensive overview of the current research progress and new perspectives on emodin's anticancer effects, which may facilitate the development of novel therapeutic strategies for cancer treatment.PMID:37732372 | DOI:10.1142/S0192415X23500787 (Source: The American Journal of Chinese Medicine)
Source: The American Journal of Chinese Medicine - September 21, 2023 Category: Complementary Medicine Authors: Wu Liu Eskandar Qaed Yuelin Zhu Wenzhang Tian Yizhen Wang Le Kang Xiaodong Ma Zeyao Tang Source Type: research

Research Progress and New Perspectives of Anticancer Effects of Emodin
In conclusion, emodin represents a promising natural compound with potent anticancer properties, and its potential as a therapeutic agent for cancer treatment warrants further investigation. This review provides a comprehensive overview of the current research progress and new perspectives on emodin's anticancer effects, which may facilitate the development of novel therapeutic strategies for cancer treatment.PMID:37732372 | DOI:10.1142/S0192415X23500787 (Source: The American Journal of Chinese Medicine)
Source: The American Journal of Chinese Medicine - September 21, 2023 Category: Complementary Medicine Authors: Wu Liu Eskandar Qaed Yuelin Zhu Wenzhang Tian Yizhen Wang Le Kang Xiaodong Ma Zeyao Tang Source Type: research