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WSSFN Society News
Stereotact Funct Neurosurg 2022;100:198 –198 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - May 2, 2022 Category: Neurosurgery Source Type: research

Leksell ’s Posteroventral Pallidotomy 1992–2022: Quo Vadis?
Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - April 12, 2022 Category: Neurosurgery Source Type: research

Brain Structures and Networks Underlying Treatment Response to Deep Brain Stimulation Targeting the Inferior Thalamic Peduncle in Obsessive-Compulsive Disorder
Conclusions: These results identify a tripartite brain network – composed of the bilateral amygdala and prefrontal regions 24 and 46 – whose engagement is associated with greater symptom improvement. They also provide information for optimizing targeting and identifying network components critically involved in ITP-DBS treatment response. Amygdala engagemen t in particular seems to be a key component for clinical benefits and could constitute a biomarker for treatment optimization.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - April 1, 2022 Category: Neurosurgery Source Type: research

Ventral Intermediate Nucleus of the Thalamus versus Posterior Subthalamic Area: Network Meta-Analysis of DBS Target Site Efficacy for Essential Tremor
Conclusion: Our systematic review highlighted both heterogeneity in scoring systems used and lack of transparency in reporting total scores, limiting direct comparison across studies. We found a modestly superior efficacy with PSA stimulation in the short term, but no difference in tremor reduction long-term.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - March 29, 2022 Category: Neurosurgery Source Type: research

A Reply to “Stereotactic Ablative Surgery in Autism: A Cocktail of Lesioned Brain Targets?”
Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - March 29, 2022 Category: Neurosurgery Source Type: research

Stereotactic Ablative Surgery in Autism: A Cocktail of Lesioned Brain Targets?
Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - March 28, 2022 Category: Neurosurgery Source Type: research

Erratum
Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - March 21, 2022 Category: Neurosurgery Source Type: research

ESSFN The Mission
Stereotact Funct Neurosurg 2022;100:142 –142 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - March 10, 2022 Category: Neurosurgery Source Type: research

ASSFN Society News
Stereotact Funct Neurosurg 2022;100:141 –141 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - March 10, 2022 Category: Neurosurgery Source Type: research

WSSFN Society News
Stereotact Funct Neurosurg 2022;100:140 –140 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - March 10, 2022 Category: Neurosurgery Source Type: research

Artifact Characterization and a Multipurpose Template-Based Offline Removal Solution for a Sensing-Enabled Deep Brain Stimulation Device
Conclusions: Artifacts present when stimulation is enabled notably affected the spectral properties of sensed signals using the Percept. Multiple discrete artifacts could be successfully removed offline using an automated template subtraction method. The presence of unrejected artifact likely influences online power estimates, with the potential to affect aDBS algorithm performance.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - February 7, 2022 Category: Neurosurgery Source Type: research

Toward Generalizable Trajectory Planning for Human Intracerebral Trials and Therapy
Conclusions: We describe an easy-to-use and generalizable protocol for intracerebral trajectory planning for stereotactic delivery of biologics. Although we highlight intracerebral stem cell delivery to the putamen using a frame-based stereotactic delivery system, similar strategies may be employed for different brain nuclei using different platforms. We anticipate this will inform future advanced and fully automated neurosurgical procedures to help unify the field and decrease inherent variability seen with manual trajectory planning.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - February 7, 2022 Category: Neurosurgery Source Type: research

Where Are We with Deep Brain Stimulation? A Review of Scientific Publications and Ongoing Research
Conclusions: This overview of past and present DBS-related studies provides insight into the status of DBS research and what we can anticipate in the future concerning new indications, improved/novel target selection and stimulation paradigms, closed-loop technology, and a better understanding of the mechanisms of action of DBS.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - February 1, 2022 Category: Neurosurgery Source Type: research

Commentary on the Continued Investigational Status of DBS for Psychiatric Indications
Behavioral disorders exact a tragic toll on patients, families, and society. Consequently, the search for better treatments is a public health priority. Recent research promises to lead to advances in psychiatric treatment that may include implantation of deep brain stimulation (DBS) devices. In this commentary, the authors discuss how promising results from initial pilot studies of DBS in treatment-resistant depression (TRD) were not validated in 2 randomized, controlled, multicenter trials. Reliance on pilot data may have contributed to the selection of primary efficacy endpoints that were not achieved, and to the undere...
Source: Stereotactic and Functional Neurosurgery - February 1, 2022 Category: Neurosurgery Source Type: research

Deep Brain Stimulation for Severe and Intractable Aggressive Behavior
Aggressive behavior in patients with intellectual disability can be resistant to pharmacological treatment and have detrimental consequences to themselves, family members, and caregivers. Hypothalamic deep brain stimulation (DBS) has been used to improve this type of behavior in severe and refractory cases. Here, we present the description and analysis of DBS of the posteromedial hypothalamus (PMH) and its long-term impact as treatment to improve severe and refractory aggressive behaviors, even with previous bilateral hypothalamotomy without improvement in patients with intellectual disability. Eleven patients underwent bi...
Source: Stereotactic and Functional Neurosurgery - January 31, 2022 Category: Neurosurgery Source Type: research