Gamma Knife Radiosurgery for Metastatic Brain Tumors from Malignant Melanomas: A Japanese Multi-Institutional Cooperative and Retrospective Cohort Study (JLGK1501)
Conclusions: The results of the present multicenter study suggest that GKRS is a relatively effective and safe modality for control of tumor progression in Japanese patients with brain metastases from malignant melanomas.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - July 3, 2018 Category: Neurosurgery Source Type: research

WSSFN Society News
Stereotact Funct Neurosurg ;96:131 –131 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - June 21, 2018 Category: Neurosurgery Source Type: research

ASSFN Society News
Stereotact Funct Neurosurg ;96:132 –132 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - June 21, 2018 Category: Neurosurgery Source Type: research

ESSFN The Mission
Stereotact Funct Neurosurg ;96:133 –134 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - June 21, 2018 Category: Neurosurgery Source Type: research

Battery Longevity Comparison of Two Commonly Available Dual Channel Implantable Pulse Generators Used for Subthalamic Nucleus Stimulation in Parkinson ’s Disease
Conclusion: The Activa PC IPG demonstrates a significantly reduced battery life of 2.1 years, with a median battery life of 4.5 years in comparison to 6.6 years in the Kinetra IPG. Future technology developments should therefore be focused on improving the battery life of the newer IPG systems.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - June 19, 2018 Category: Neurosurgery Source Type: research

Development of a Standardized Cranial Phantom for Training and Optimization of Functional Stereotactic Operations
Conclusions: This cranial phantom is a simple and effective model to simulate functional and stereotactic neurosurgical operations. This might be useful for teaching and training of neurosurgeons, establishing operations in a new center and for optimization of radiological examinations.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - June 13, 2018 Category: Neurosurgery Source Type: research

Intrathecal Baclofen Therapy for Painful Muscle Spasms in a Patient with Friedreich ’s Ataxia
This report describes the successful management of painful spasms in a 65-year-old woman with FA via intrathecal baclofen (ITB) therapy followin g unsuccessful medical treatments. To our knowledge, this is the third reported case in the literature. Unfortunately, the pathophysiological characteristics of muscle spasms in FA are not well explored and understood while the therapeutic mechanisms of the different treatments are rather vague. Tak ing into consideration the suggested spinal atrophy in FA, the clinical resemblance of FA and chronic spinal injury muscle spasms, together with the rapid ITB therapy effectiveness in ...
Source: Stereotactic and Functional Neurosurgery - June 8, 2018 Category: Neurosurgery Source Type: research

Estimating Accurate Target Coordinates with Magnetic Resonance Images by Using Multiple Phase-Encoding Directions during Acquisition
Conclusion: Acquiring MR in multiple phase-encoding directions and selecting axes according to the phase-encoding direction allows identification of more accurate coordinates for stereotactic procedures.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - June 1, 2018 Category: Neurosurgery Source Type: research

Subthalamic Nucleus Visualization on Routine Clinical Preoperative MRI Scans: A Retrospective Study of Clinical and Image Characteristics Predicting Its Visualization
Conclusion: STN visualization is only fair to good on routine MRI with good concordance of interindividual rating. Advancing age and decreased white matter are associated with poor visualization of the STN. Knowledge about factors contributing to poor visualization of the STN could alert a surgeon to modify the imaging strategy to optimize surgical targeting.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - May 30, 2018 Category: Neurosurgery Source Type: research

Asleep Deep Brain Stimulation Reduces Incidence of Intracranial Air during Electrode Implantation
Conclusions: We show that aDBS reduces the incidence of intracranial air, larger air volumes, and cortical brain shift. Large volumes of intracranial air have been correlated to shifting of brain structures during DBS procedures, a variable that could impact accuracy of electrode placement.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - May 30, 2018 Category: Neurosurgery Source Type: research

Atlas-Independent, Electrophysiological Mapping of the Optimal Locus of Subthalamic Deep Brain Stimulation for the Motor Symptoms of Parkinson Disease
Conclusion: Our novel, atlas-independent method reveals a single, ovoid optimal locus of stimulation in STN DBS for PD. The methodology, here applied to UPDRS and PD, is generalizable to atlas-independent mapping of other motor and non-motor effects of DBS.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - May 29, 2018 Category: Neurosurgery Source Type: research

Subcaudate Tractotomy White Matter Anatomy and Variability: A Diffusion Tensor Imaging Study
Conclusion: We have demonstrated a detailed analysis of the white matter tracts and their anatomical variability underlying subcaudate tractotomy. This has significant implications for neurosurgical targeting.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - May 16, 2018 Category: Neurosurgery Source Type: research

Gamma Knife Stereotactic Radiosurgery for the Treatment of Brain Metastases from Primary Tumors of the Urinary Bladder
Conclusions: The prognosis in this patient population remains guarded. Factors associated with improved survival include intracranial resection. Future, prospective work is needed to further define optimal management.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - April 26, 2018 Category: Neurosurgery Source Type: research

WSSFN Society News
Stereotact Funct Neurosurg 2018;96:67 –67 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - April 12, 2018 Category: Neurosurgery Source Type: research

ASSFN Society News
Stereotact Funct Neurosurg 2018;96:68 –68 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - April 12, 2018 Category: Neurosurgery Source Type: research

ESSFN Mission
Stereotact Funct Neurosurg 2018;96:69 –69 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - April 12, 2018 Category: Neurosurgery Source Type: research

Hyperbaric Oxygen Therapy as Adjuvant Treatment for Hardware-Related Infections in Neuromodulation
Conclusions: This study indicates a potential benefit of adjuvant HBOT in the treatment of hardware-related infections in neuromodulation, diminishing the need for hardware removal and treatment interruption. Prospective studies are warranted to establish the role of adjuvant HBOT in the treatment of hardware-related infections in neuromodulation.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - April 3, 2018 Category: Neurosurgery Source Type: research

A Retrospective Analysis of the Outcomes of Dural Arteriovenous Fistulas Treated with Gamma Knife Radiosurgery: A Single-Institution Experience
Conclusions: GKRS is a safe and effective treatment modality for DAVF in combination with a traditional treatment option such as endovascular embolization or microsurgery.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - March 14, 2018 Category: Neurosurgery Source Type: research

Prelimbic Cortex Deep Brain Stimulation Reduces Binge Size in a Chronic Binge Eating Rat Model
Conclusions: This study suggests that low-frequency prelimbic cortex stimulation in BE would be useful for correcting prefrontal hypofunction which is strongly associated with BE and addiction pathogenesis.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - March 14, 2018 Category: Neurosurgery Source Type: research

Venous Thromboembolism during Interventional MRI-Guided Stereotactic Surgery
Conclusions: The incidence of postoperative VTE is low following iMRI procedures, even without the use of PCD during surgery.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - March 1, 2018 Category: Neurosurgery Source Type: research

A Novel Animal Model of Parkinson ’s Disease Using Optogenetics: Representation of Various Disease Stages by Modulating the Illumination Parameter
Conclusions: An optogenetic PD model has the advantage of more appropriately representing various PD stages by controlling illumination parameters.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - February 14, 2018 Category: Neurosurgery Source Type: research

ESSFN The Mission
Stereotact Funct Neurosurg 2017;95:431 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - February 13, 2018 Category: Neurosurgery Source Type: research

ASSFN Society News
Stereotact Funct Neurosurg 2017;95:430 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - February 13, 2018 Category: Neurosurgery Source Type: research

WSSFN Society News
Stereotact Funct Neurosurg 2017;95:429 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - February 13, 2018 Category: Neurosurgery Source Type: research

Contents Vol. 95, 2017
Stereotact Funct Neurosurg 2017;95:I-IV (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - February 12, 2018 Category: Neurosurgery Source Type: research

Thalamic Deep Brain Stimulation Salvages Failed Focused Ultrasound Thalamotomy for Essential Tremor: A Case Report
Conclusion: This case demonstrates that thalamic DBS can salvage a failed FUS thalamotomy and also the feasibility of stimulating a previously lesioned target.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - February 12, 2018 Category: Neurosurgery Source Type: research

DBStar: An Open-Source Tool Kit for Imaging Analysis with Patient-Customized Deep Brain Stimulation Platforms
Conclusions: DBStar is a robust tool kit for understanding the anatomical location and context of electrode locations, and can easily be used for imaging, behavioral, or electrophysiological analyses.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - February 7, 2018 Category: Neurosurgery Source Type: research

Battery Life Matters in Deep Brain Stimulation
Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - February 7, 2018 Category: Neurosurgery Source Type: research

Prelemniscal Lesion for Selective Improvement of Parkinson Disease Tremor
Conclusion: Selective improvement of symptoms is feasible in patients with a predominantly monosymptomatic PD clinical presentation.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - February 6, 2018 Category: Neurosurgery Source Type: research

Theoretical Effect of DBS on Axonal Fibers of Passage: Firing Rates, Entropy, and Information Content
Conclusions: (1) The results imply that DBS effects are due to entropy reduction within fibers, i.e.,a reduction in their information. (2) Where fibers of passage do not terminate in target regions, DBS may have side effects on nontargeted circuitry.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - January 26, 2018 Category: Neurosurgery Source Type: research

MRI-Guided Interstitial Laser Ablation for Intracranial Lesions: A Large Single-Institution Experience of 133 Cases
Conclusion: Our series suggests that ILA is a safe and efficacious treatment for a variety of intracranial pathologies, can be tailored to treat difficult-to-access lesions, and may offer a novel alternative to open craniotomy in properly selected patients.Stereotact Funct Neurosurg 2017;95:417-428 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - January 16, 2018 Category: Neurosurgery Source Type: research

Double Anterior Stereotactic Cingulotomy for Intractable Oncological Pain
Conclusions: Our initial experience indicates that double stereotactic cingulotomy is safe and effective in alleviating refractory oncological pain.Stereotact Funct Neurosurg 2017;95:400-408 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - January 9, 2018 Category: Neurosurgery Source Type: research

O-Arm-Guided Percutaneous Radiofrequency Cordotomy
Conclusion: Percutaneous cordotomy using the O-Arm is safe and effective in the treatment of intractable oncological pain.Stereotact Funct Neurosurg 2017;95:409-416 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - January 9, 2018 Category: Neurosurgery Source Type: research

Optical Measurements during Deep Brain Stimulation Lead Implantation: Safety Aspects
Conclusion: Real-time LDF measurement of the microcirculation using a forward-looking probe during DBS surgery can detect blood flow peaks and further minimize the risk of developing ICH. No separate guide tube is necessary as the probe also creates the trajectory for the DBS lead.Stereotact Funct Neurosurg 2017;95:392-399 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - January 4, 2018 Category: Neurosurgery Source Type: research

Surgical Management of Deep Brain Stimulator Scalp Erosion without Hardware Removal
Conclusions: DBS scalp erosion can be managed by rotational scalp flap without hardware removal, even in cases where infection is identified.Stereotact Funct Neurosurg 2017;95:385-391 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - December 12, 2017 Category: Neurosurgery Source Type: research

Ruptured de novo Aneurysm following Gamma Knife Surgery for Arteriovenous Malformation: Case Report
We present a rare case of a radiation-induced ruptured de novo aneurysm following Gamma Knife surgery (GKS) for an AVM. A 17-year-old, right-handed male underwent GKS for AVM at the left parietal lobe. After 3 years, a follow-up angiogram showed a residual AVM at the angular gyrus. Then, a 2nd GKS was performed for the residual lesion. Six years after the 1st GKS, the AVM disappeared on the angiogram. Seven years later, he suffered a sudden onset of headache. A left carotid angiogram revealed a ruptured aneurysm at the M2-M3 junction of the middle cerebral artery parietal branch. Coil embolization was performed, and the an...
Source: Stereotactic and Functional Neurosurgery - November 30, 2017 Category: Neurosurgery Source Type: research

ESSFN Mission
Stereotact Funct Neurosurg 2017;95:361 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - November 3, 2017 Category: Neurosurgery Source Type: research

ASSFN Society News
Stereotact Funct Neurosurg 2017;95:360 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - November 3, 2017 Category: Neurosurgery Source Type: research

WSSFN Society News
Stereotact Funct Neurosurg 2017;95:359 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - November 3, 2017 Category: Neurosurgery Source Type: research

Significant Hemorrhage Rate Reduction after Gamma Knife Radiosurgery in Symptomatic Cavernous Malformations: Long-Term Outcome in 95 Case Series and Literature Review
Conclusions: The best dosage range for preventing bleeding was identified as between 11 and 12 Gy in our series. Although the efficacy of radiosurgery in CMs remains impossible to quantify, a very significant reduction in the bleeding rate occurs after a 3-year latency interval. No permanent neurological morbidity is reported in our series. These results defend the safety of GKRS in surgical high-risk CM from the first bleeding event.Stereotact Funct Neurosurg 2017;95:369-378 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - November 3, 2017 Category: Neurosurgery Source Type: research

Gamma Knife Stereotactic Radiosurgery for the Treatment of Primary and Metastatic Ocular Malignancies
Conclusion: GKR is an effective option, with acceptable levels of toxicity, in the treatment of primary and metastatic ocular lesions.Stereotact Funct Neurosurg 2017;95:363-368 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - November 3, 2017 Category: Neurosurgery Source Type: research

Factors Affecting Stereotactic Accuracy in Image-Guided Deep Brain Stimulator Electrode Placement
Background/Aims: Intraoperative imaging allows near-real-time assessment of stereotactic accuracy during implantation of deep brain stimulation (DBS) electrodes. Such technology can be used to examine factors impacting stereotactic error.Methods: Intraoperative CT imaging was reviewed in patients undergoing DBS placement at Oregon Health and Sciences University. Coordinates of the target electrode were compared to the operative plan to characterize the magnitude and direction of stereotactic error with respect to side of implantation, target, and electrode approach angles.Results: One hundred sixty-nine leads in 94 patient...
Source: Stereotactic and Functional Neurosurgery - October 25, 2017 Category: Neurosurgery Source Type: research

Hemorrhage Detection and Incidence during Magnetic Resonance-Guided Deep Brain Stimulator Implantations
Conclusions: Hemorrhage was readily apparent on intraoperative imaging, and hemorrhage rates for iMRI-guided DBS implantations were comparable to those for conventional implantation approaches.Stereotact Funct Neurosurg 2017;95:307-314 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - October 25, 2017 Category: Neurosurgery Source Type: research

ESSFN Mission
Stereotact Funct Neurosurg 2017;95:289 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - October 25, 2017 Category: Neurosurgery Source Type: research

ASSFN Society News
Stereotact Funct Neurosurg 2017;95:288 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - October 25, 2017 Category: Neurosurgery Source Type: research

WSSFN Society News
Stereotact Funct Neurosurg 2017;95:287 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - October 25, 2017 Category: Neurosurgery Source Type: research

Infection and Erosion Rates in Trials of a Cranially Implanted Neurostimulator Do Not Increase with Subsequent Neurostimulator Placements
Conclusion: These data indicate that the risk for infection compares favorably to other neurostimulation devices and suggest that rates of infection and erosion do not increase with subsequent neurostimulator replacements.Stereotact Funct Neurosurg 2017;95:325-329 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - October 25, 2017 Category: Neurosurgery Source Type: research

The Relationship of Electrophysiologic Subthalamic Nucleus Length as a Predictor of Outcomes in Deep Brain Stimulation for Parkinson Disease
Background: Intraoperative measurement of subthalamic nucleus (STN) width through microelectrode recording (MER) is a common proxy for optimal electrode location during deep brain stimulation (DBS) surgery for Parkinson disease. We assessed whether the MER-determined STN width is a predictor of postoperative Unified Parkinson Disease Rating Scale (UPDRS) improvement.Methods: Records were reviewed for patients who underwent single-sided STN DBS placement for Parkinson disease between 2005 and 2010 at the UAB Medical Center. Reviews of preoperative and 3-month postoperative UPDRS part III, intraoperative MER records, and pos...
Source: Stereotactic and Functional Neurosurgery - October 25, 2017 Category: Neurosurgery Source Type: research

Intraoperative Neurophysiological Monitoring (Motor and Somatosensory Evoked Potentials) in Dorsal Root Entry Zone Lesioning for Brachial Plexus Avulsion Pain
Conclusion: Significant events on IONM were common during DREZ lesioning for brachial plexus avulsion pain and were closely related to the occurrence of postoperative neurological deficits.Stereotact Funct Neurosurg 2017;95:330-340 (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - October 25, 2017 Category: Neurosurgery Source Type: research

Impact of the Number of Metastatic Tumors Treated by Stereotactic Radiosurgery on the Dose to Normal Brain: Implications for Brain Protection
Purpose/Objectives: The purpose of this study was to evaluate the effect of the number of brain lesions for which stereotactic radiosurgery (SRS) was performed on the dose volume relationships in normal brain.Materials and Methods: Brain tissue was segmented using the patient's pre-SRS MRI. For each plan, the following data points were recorded: total brain volume, number of lesions treated, volume of brain receiving 8 Gy (V8), V10, V12, and V15.Results: A total of 225 Gamma Knife ® treatments were included in this retrospective analysis. The number of lesions treated ranged from 1 to 29. The isodose for prescription r...
Source: Stereotactic and Functional Neurosurgery - October 25, 2017 Category: Neurosurgery Source Type: research