Stereotactic and Functional Neurosurgery This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

A Phase 2 Randomized Trial of Asleep versus Awake Subthalamic Nucleus Deep Brain Stimulation for Parkinson ’s Disease
Conclusions: Owing to its randomized design, our study supports the hypothesis that motor outcomes after asleep STN-DBS in PD may be noninferior to the standard awake procedure.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - November 30, 2020 Category: Neurosurgery Source Type: research

Trends in Clinical Trials for Spinal Cord Stimulation
Conclusions: A large number of clinical trials of SCS are underway. Improvements in the treatment of pain and novel indications for SCS constitute the majority of studies. This overview of SCS-related clinical trials provides a window into future new indications, novel stimulation techniques, and a heightened understanding of the mechanisms of action.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - November 27, 2020 Category: Neurosurgery Source Type: research

Successful Unilateral Surgical Approach to Internal Globus Pallidus and Ventral Intermediate Nucleus of the Thalamus in 3 Cases of Myoclonus-Dystonia Syndrome
Surgical approaches of internal globus pallidus (GPi) and ventral intermediate thalamic nucleus (Vim) have been used to treat different movement disorders. Three subjects with myoclonus-dystonia syndrome were surgically treated, one of them with GPi and Vim stimulation, while radiofrequency ablation of these structures was performed in the other 2 subjects. Surgical approach of both targets was performed simultaneously on each subject. Mean follow-up was of 33.3 months (22 –48 months), the Unified Myoclonus Rating Scale action myoclonus (AM), functional tests (FT), patient questionnaire (PQ) sub-scores, and the Unified D...
Source: Stereotactic and Functional Neurosurgery - November 26, 2020 Category: Neurosurgery Source Type: research

Development of a Stereotactic Radiosurgery Frame Adapter for a Multichannel MRI Coil
Conclusion: Compared with single-channel coils, the use of multichannel MRI coils with a newly developed frame adapter is expected to ensure successful SRS treatments with improved geometrical accuracy and SNR.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - November 26, 2020 Category: Neurosurgery Source Type: research

Is Glutamine Responsible for the Radiosensitivity of Subthalamic Nucleus?
Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - November 23, 2020 Category: Neurosurgery Source Type: research

Endurance of Short Pulse Width Thalamic Stimulation Efficacy in Intention Tremor
The benefit of short pulse width stimulation in patients suffering from essential tremor (ET) refractory to thalamic deep brain stimulation remains controversial. Here, we add to the minimal body of evidence available by reporting the effect of this type of stimulation in 3 patients with a persistent and severe intention tremor component despite iterative DBS setting adjustments. While a reduction in pulse width to 30 μs initially showed promise in these patients by improving tremor control and mitigating cerebellar side effects arguably by widening the therapeutic window, these benefits seemed to dissipate during early f...
Source: Stereotactic and Functional Neurosurgery - November 23, 2020 Category: Neurosurgery Source Type: research

Accuracy and Safety of Customized Stereotactic Fixtures for Stereoelectroencephalography in Pediatric Patients
In conclusion, patient-customized stereotactic fixtures are a safe and accurate option for SEEG exploration in young children.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - November 23, 2020 Category: Neurosurgery Source Type: research

Constant Current versus Constant Voltage: Clinical Evidence Supporting a Fundamental Difference in the Modalities
Conclusions: In this case series, we provide clinical support for the principal differences between CV and CC stimulation.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - November 23, 2020 Category: Neurosurgery Source Type: research

Prospective Evaluation of the Time Course of White Matter Edema Associated with Implanted Deep Brain Stimulation Electrodes
Conclusion: In this study, we obtained a regimented series of postoperative MRIs in an effort to determine the time course and incidence of edema. Our results show that edema following DBS implant is not rare, is often asymptomatic, and may resolve over many weeks.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - November 20, 2020 Category: Neurosurgery Source Type: research

Bilateral Pallidal Stimulation with Directional Leads for Primary Focal Lingual Dystonia
There have been limited studies regarding stereotactic and functional neurosurgery for lingual dystonia. Here, we report a patient with primary lingual dystonia who showed significant improvement after bilateral deep brain stimulation (DBS). A 42-year-old woman presented with a 5- to 6-year history of tongue protrusion; however, she lacked a significant medical or medication history before onset. She presented with gradually worsening symptoms and was diagnosed with idiopathic lingual dystonia. Her tongue was injected with botulinum toxin on 6 occasions; however, it had a limited effect. Oral medications were ineffective. ...
Source: Stereotactic and Functional Neurosurgery - November 18, 2020 Category: Neurosurgery Source Type: research

Sustained Relief after Pallidal Stimulation Interruption in Tourette ’s Syndrome Treated with Simultaneous Capsulotomy
Conclusion: Bilateral GPi-DBS combined with anterior capsulotomy appears to result in marked and sustained improvements in TS symptoms and psychiatric comorbidities, which are fully maintained over time, even without pallidal stimulation.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - November 18, 2020 Category: Neurosurgery Source Type: research

The Medial Subthalamic Nucleus Border as a New Anatomical Reference in Stereotactic Neurosurgery for Parkinson ’s Disease
Conclusion: The medial STN border is applicable across centers as a reference point for STN DBS surgery for PD and seems suitable in order to account for interindividual and intraindividual anatomical variability if one is aware of the discrepancies between T2-weighted imaging and SWI.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - November 18, 2020 Category: Neurosurgery Source Type: research

The Effects of Deep Brain Stimulation of the Subthalamic Nucleus on Vascular Endothelial Growth Factor, Brain-Derived Neurotrophic Factor, and Glial Cell Line-Derived Neurotrophic Factor in a Rat Model of Parkinson ’s Disease
Conclusions: The upregulation of trophic factors induced by STN-DBS may participate in its long-term therapeutic efficacy and potentially neuroprotective effects.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - November 5, 2020 Category: Neurosurgery Source Type: research

Electrical Stimulation of Subiculum for the Treatment of Refractory Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis: A 2-Year Follow-Up Study
Conclusions: Subiculum stimulation is effective for FBTCS reduction in patients with MTLE and HS, suggesting that the subiculum mediates the generalization rather than the genesis of mesial temporal lobe seizures. Better results are observed at longer follow-up times.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - October 28, 2020 Category: Neurosurgery Source Type: research

Pallidal Deep Brain Stimulation in Patients with Prior Bilateral Pallidotomy and Selective Peripheral Denervation for Treatment of Dystonia
Conclusions: Pallidal DBS can yield marked and long-lasting improvement in patients who underwent both pallidotomy and selective peripheral denervation earlier. Therefore, such patients, in general, should not be excluded from DBS.Stereotact Funct Neurosurg (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - October 20, 2020 Category: Neurosurgery Source Type: research