Complementary and Alternative Therapies for Onychomycosis: A Systematic Review of the Clinical Evidence
Conclusion: Given the rise of antifungal resistance, complementary and alternative therapies should continue to be studied as adjunctive or alternative therapy for onychomycosis. While preliminary evidence exists for several complementary and alternative therapies in the treatment of onychomycosis, large-scale, randomized, placebo-controlled trials are needed prior to endorsing their use to patients.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - February 9, 2022 Category: Dermatology Source Type: research
Bazex Syndrome Associated with Squamous Cell Carcinoma of the Lip: A Rare Paraneoplastic Acrokeratosis with Nail Dystrophy
Conclusions: In 70% cases of APB, nail changes precede the diagnosis of the underlying neoplasm by up to 10 months, offering a good lead-time for early suspicion of malignancy. Our case highlights the importance of recognizing these changes early. An atypical location of malignancy (lower lip) and rare presentations, including painful acrokeratosis, melanonychia striata, and chloronychia, as seen in our case, should also be kept in mind.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - January 31, 2022 Category: Dermatology Source Type: research
Multiple Clinical Manifestations of Lichenoid Spectrum: A Patient with Frontal Fibrosing Alopecia, Lichen Planus Pigmentosus, and Nail Lichen Planus
Conclusion: In recent years, it has been established that FFA can be associated with LPP and it is thought to be a variant of lichen planopilaris. Nail involvement is rarely reported in FFA or LPP. To our knowledge, the presence of the three conditions in the same patient has not been previously reported. Although rare we would like to emphasize the importance of a careful examination of the nails in patients with FFA and/or LPP to prevent irreversible nail changes.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - January 28, 2022 Category: Dermatology Source Type: research
Postpartum Telogen Effluvium Unmasking Traction Alopecia
Conclusion: TE can unmask underlying TA. Awareness of this phenomenon is critical to appropriate diagnosis and treatment.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - January 28, 2022 Category: Dermatology Source Type: research
Intermammary Hidradenitis Suppurativa
Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - January 26, 2022 Category: Dermatology Source Type: research
A Case of Pemphigus Vulgaris and Hidradenitis Suppurativa: May Systemic Steroids Be Considered in the Standard Management of Hidradenitis Suppurativa?
Conclusion: There are few data in the literature on the use of systemic corticosteroids for the two diseases, and our article wants to be a food for thought on the management and treatment of these diseases.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - January 26, 2022 Category: Dermatology Source Type: research
Chronic Retronychia: Nonsurgical Treatment
Conclusion: By combining a healthy nail growth and the simultaneous protection of the nail, we were able to achieve a normal nail in all cases. In order to maintain the achieved results, we recommended our patients to continue wearing protective tubes whenever they would wear closed shoes because recurrence of retronychia may occur even after minimal trauma.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - January 21, 2022 Category: Dermatology Source Type: research
Dermatitis Cruris Pustulosa et Atrophicans: Scarring Alopecia Beyond Scalp Hair
Dermatitis Cruris Pustulosa et Atrophicans (DCPA) was first described in 1952 in Nigeria and is nowadays regarded as a type of chronic folliculitis of tropical areas. It is often limited to the lower limbs of young adults, mostly in the second to third decades, with a unique clinical picture characterized by chronicity, relentless progression, therapy refractoriness, and permanent cicatricial changes. Trauma, occlusion, and microorganism selection contribute for its etiopathogenesis, which is deemed multifactorial but still incompletely understood. Despite its conspicuous clinical features, awareness of DCPA is apparently ...
Source: Skin Appendage Disorders - January 19, 2022 Category: Dermatology Source Type: research
Racial, Ethnic, and Sex Disparities in Nail Psoriasis Clinical Trials: A Systematic Review
Conclusion: Reporting of racial/ethnic demographics is lacking in NP RCTs. Women and racial/ethnic minorities remain underrepresented in NP research. There is a need for increased reporting and diversification of NP clinical trial participants.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - January 14, 2022 Category: Dermatology Source Type: research
An Unusual Case of Pemphigus Vulgaris
Conclusion: Our case may be useful in the literature to identify cases of PF with atypical manifestations that may mimic other diseases.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - January 11, 2022 Category: Dermatology Source Type: research
How to Deal with the Issues of Fertility, Malignancies, and the Postfinasteride Syndrome while Prescribing Finasteride for Male Pattern Hair Loss
Oral finasteride represented a breakthrough for treatment of male pattern hair loss (MPHL), with clinical studies having demonstrated high efficacy of treatment and a favorable safety profile. And yet, fertility issues, malignancy, and postfinasteride syndrome have been concerns of users and prescribers of the drug. Pre-existing mental health disorder may put patients at an increased risk of nocebo, while the prevalence of personality disorders in subjects with MPHL is known to be higher than in the general population, specifically histrionic personality disorder. We devised a system for patient selection and risk assessme...
Source: Skin Appendage Disorders - January 10, 2022 Category: Dermatology Source Type: research
Guidance on COVID-19 Vaccination in Hidradenitis Suppurativa Patients: A Modified Delphi Consensus of Experts
Conclusion: For now, this consensus can serve as a resource for clinicians discussing COVID-19 vaccination with their HS patients. These recommendations will need to be updated as new evidence on COVID-19 emerges.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - January 10, 2022 Category: Dermatology Source Type: research
Efficacy and Tolerability of Methotrexate in the Treatment of Severe Paediatric Alopecia Areata
Conclusion: MTX was shown to have variable efficacy for the treatment of paediatric AA with overall good tolerability. MTX can be considered in the treatment of severe refractory AA for children.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - January 10, 2022 Category: Dermatology Source Type: research
Holiday Reindeer Trivia for Physicians Who Like Hair and Nails
Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - January 10, 2022 Category: Dermatology Source Type: research
Epidemiological, Clinical, Trichoscopic, and Histopathological Features of Lupus Erythematous Mimicking Alopecia Areata: A Multicenter Retrospective Study
Conclusion: Trichoscopy was found as an essential first step for the patchy alopecia diagnosis, enabling to differentiate LE from AA. Putting it mildly, trichoscopy raises the suspicion that leads to a biopsy, increasing the diagnostic accuracy with better outcome for patients.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - January 3, 2022 Category: Dermatology Source Type: research
