Acute Paronychia and Onychomadesis after a “Russian” Manicure: A New, Aggressive, and Destructive Form of Manicure for Dermatologists to Recognize
Conclusion: As this style of manicure is being inaccurately publicized as safe, it is important that dermatologists are aware of this technique and educate our patients about its potential for harm.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - May 31, 2022 Category: Dermatology Source Type: research
Successful Response to a Combination of Intralesional Methotrexate and Fractional CO < sub > 2 < /sub > Laser in Refractory Alopecia Areata: Case Report
Conclusion: Previous research encompasses a total of 23 patients. Most patients presented with patchy AA. The doses administered ranged from 2.5 to 50 mg with an average frequency of 3 weeks. On average, most patients required a minimum of 3 sessions. One case employed 1% topical methotrexate ointment. Adverse local events were mild and transient. In conclusion, the concomitant application of these treatments has not been reported previously. Specific recommendations relating to the appropriate dosing of the drug, frequency of administration, and requirements for analytical control studies should be determined in further s...
Source: Skin Appendage Disorders - May 24, 2022 Category: Dermatology Source Type: research
Thiamethoxam-Induced Subclinical Onychomadesis
Conclusion: Thiamethoxam is an over-the-counter broad-spectrum insecticide used for houseplants, but its safety data does not mention acute adverse effects on nails, which was a novel finding in our patient. The safety data does mention the use of gloves for preparing and administering the product. Secondary bacterial and fungal infections, which can occur after the initial insult, further worsen the prognosis.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - May 24, 2022 Category: Dermatology Source Type: research
Giant Koenen Tumors as the Presenting and Only Clinical Sign of Tuberous Sclerosis Complex in a 56-Year-Old Man and Its Surgical Management
Discussion: The association between KTs and intellectual disability with TSC supported the clinical diagnosis. To date, there is no standard first-line treatment for KTs. Complete surgical excision up to the proximal base of the tumor offers satisfactory results in terms of functionally and esthetic appearance and could be considered the preferred therapeutic modality for patients with severe functional and cosmetic impairment. Prompt recognition of the many signs and symptoms associated with TSC is important to achieve early diagnosis, preventing further complications.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - May 23, 2022 Category: Dermatology Source Type: research
Trichoscopy-Derived Hairline Recession Equivalent in Monitoring Frontal Fibrosing Alopecia
Conclusion: The hair density profile may be a useful tool to characterize different disease progression patterns. The HRE is potentially a very accurate and sensitive parameter to quantify local hair loss progression in FFA.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - May 19, 2022 Category: Dermatology Source Type: research
Efficacy of Subantimicrobial, Modified-Release Doxycycline Compared to Regular-Release Doxycycline for the Treatment of Hidradenitis Suppurativa
Conclusion: MR-DC demonstrated comparable efficacy to RR-DC in the treatment of HS. MR-DC may serve as a valuable alternative to other antibiotic regimes, considering its anti-inflammatory properties and its lower potential to induce antibiotic resistance.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - May 13, 2022 Category: Dermatology Source Type: research
Efficiency of Hair Detection in Hair-to-Hair Matched Trichoscopy
Conclusion: Combination of manually corrected image processing, follicular mapping, and hair-to-hair matching appears to be the most precise way of evaluating the change in hair count over time. These novel techniques should be considered valuable, especially in research and clinical trials.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - May 12, 2022 Category: Dermatology Source Type: research
Branching Dilated Vessels: A Possible Trichoscopic Clue for Diagnosis of Erosive Pustular Dermatosis of the Scalp in Children
We describe the usefulness of trichoscopy as a supportive diagnostic tool in 2 cases of pediatric EPDS.Discussion: Clinical distinction between EPDS and different types of alopecia in children is difficult, with a significant likelihood of diagnostic errors and delay in therapy. Trichoscopy may provide a noninvasive option that can help avoid invasive diagnostic procedures in children.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - May 12, 2022 Category: Dermatology Source Type: research
Myofibroblasts, B Cells, and Mast Cells in Different Types of Long-Standing Acne Scars
In conclusion, myofibroblasts are abundant only in hypertrophic acne scars, and mast cells, but not B cells, might play an important role in the pathogenesis of long-standing acne scars.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - May 12, 2022 Category: Dermatology Source Type: research
New Normal Mask-Wearing and Its Impact on Underneath Skin Microbiome: A Cross-Sectional Study in Mild Acne Vulgaris Patients
Conclusion: Our results showed no significant impact of mask-wearing on the skin microbiota in mild acne vulgaris participants.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - May 6, 2022 Category: Dermatology Source Type: research
Nail Clipping with PAS Stain and Correlation with Fungi Isolated in Culture: A Valuable Exchange in the Diagnosis of Onychomycosis
Conclusions: Although not a substitute for culture, microscopic analysis of fungal structures offers good accuracy for differentiating agents of onychomycosis.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - May 5, 2022 Category: Dermatology Source Type: research
Vaccine Toes Are the New COVID Toes
Conclusion: The rising number of reports of pernio-like lesions associated with COVID-19 vaccination underlines the importance of the pathophysiological state of the vaccinated patient and how it relates to dermatological manifestations. Pernio-like lesions are thought to represent a robust host immune antiviral response related to production of interferon-1 in the setting of primary infection; incidences occurring after vaccination further support this theory. Unfortunately, media-generated reports of such reactions have the potential to inflame distrust and fear of the vaccine among the general public. Given the previous...
Source: Skin Appendage Disorders - April 28, 2022 Category: Dermatology Source Type: research
Supravenous Repigmentation of Hair Shafts in a Patient with Regrowing Alopecia Totalis: A Case Report and Hypothesis
Conclusion: Loss of pigmentation and subsequent repigmentation of the hair shaft in regrowing AA is not entirely understood. Initial hair regrowth in AA tends to be fine and depigmented, although the hair will usually regain normal texture and color. Pigmentation following a vein suggests that local temperature may play a role, possibly augmented by corticosteroid induced reduced expression of inflammatory cytokines and endothelial release of the vasoconstrictor hormone endothelin, which stimulates melanogenesis.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - April 28, 2022 Category: Dermatology Source Type: research
Mycophenolate Mofetil in the Treatment of Severe Corticosteroid-Dependent or Corticosteroid-Resistant Nail Lichen Planus: A Case Series of 5 Patients
Conclusion: MMF may be a treatment to consider for severe corticosteroid-dependent or corticosteroid-resistant NLP. The long-term safety of this treatment warrants further investigation.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - April 27, 2022 Category: Dermatology Source Type: research
Dermoscopic Findings of Discoid Lupus Erythematosus Involving the Eyelids
Conclusion: This study highlights the importance of performing a dermoscopy examination to help physicians obtain an early diagnosis of DLE.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - April 25, 2022 Category: Dermatology Source Type: research
