Brief history of the Society for Melanoma Research: A community of clinicians, researchers, and friends
Pigment Cell Melanoma Res. 2023 Sep 27. doi: 10.1111/pcmr.13124. Online ahead of print.ABSTRACTTo commemorate the 20th Anniversary of the Society of Melanoma Research and the first International Melanoma Research Congress held in June of 2003, we have described in brief, how the Society for Melanoma Research (SMR) began, the purpose, goals, and governance of the SMR, and how the society has evolved to support new melanoma researchers. In celebration of the immense progress in treating melanoma patients over the last 20 years and the impact of the SMR on these advances, we have highlighted memories and insight from early SM...
Source: Pigment Cell and Melanoma Research - September 28, 2023 Category: Cytology Authors: Vito W Rebecca Jessie Villanueva Marie R Webster Source Type: research

A meta-analysis of the placebo response in vitiligo: Causes and consequences for the interpretation of clinical trials
Pigment Cell Melanoma Res. 2023 Sep 27. doi: 10.1111/pcmr.13132. Online ahead of print.ABSTRACTThe current understanding of the placebo response in vitiligo is limited. Nonetheless, it is difficult to compare the outcomes of vitiligo trials if the repigmentation rates in placebo patients vary significantly. We conducted a meta-analysis of the placebo response in vitiligo trials. Overall, repigmentation rates in patients receiving placebo were 22%, ranging substantially from 0 to 60%. Repigmentation (>25%) was still relatively common for placebo (9.35%), but fell to 5% when >50% improvement was analyzed. Higher freque...
Source: Pigment Cell and Melanoma Research - September 27, 2023 Category: Cytology Authors: Reinhart Speeckaert Marijn M Speeckaert Nanja van Geel Source Type: research

Anti-melanogenic effect of exosomes derived from human dermal fibroblasts (BJ-5ta-Ex) in C57BL/6 mice and B16F10 melanoma cells
Pigment Cell Melanoma Res. 2023 Sep 27. doi: 10.1111/pcmr.13135. Online ahead of print.ABSTRACTExosomes are involved in intercellular communication by transferring cargo between cells and altering the specific functions of the target cells. Recent studies have demonstrated the therapeutic effects of exosomes in several skin diseases. However, understanding of the effects of exosomes on anti-pigmentation is limited. Therefore, we investigated whether BJ-5ta exosomes (BJ-5ta-Ex) derived from human foreskin fibroblasts regulate melanogenesis and delineated the underlying mechanism. Interestingly, treatment with BJ-5ta-Ex indu...
Source: Pigment Cell and Melanoma Research - September 27, 2023 Category: Cytology Authors: Jung Min Lee Jung Ok Lee Yujin Kim You Na Jang A Yeon Park Su-Young Kim Hye Sung Han Beom Joon Kim Kwang Ho Yoo Source Type: research

Twenty years of research in melanoma therapy-From "nothing works" to cures: A personal account
Pigment Cell Melanoma Res. 2023 Sep 19. doi: 10.1111/pcmr.13133. Online ahead of print.NO ABSTRACTPMID:37726985 | DOI:10.1111/pcmr.13133 (Source: Pigment Cell and Melanoma Research)
Source: Pigment Cell and Melanoma Research - September 20, 2023 Category: Cytology Authors: Meenhard Herlyn Jessie Villanueva Source Type: research

Twenty years of research in melanoma therapy-From "nothing works" to cures: A personal account
Pigment Cell Melanoma Res. 2023 Sep 19. doi: 10.1111/pcmr.13133. Online ahead of print.NO ABSTRACTPMID:37726985 | DOI:10.1111/pcmr.13133 (Source: Pigment Cell and Melanoma Research)
Source: Pigment Cell and Melanoma Research - September 20, 2023 Category: Cytology Authors: Meenhard Herlyn Jessie Villanueva Source Type: research

Twenty years of research in melanoma therapy-From "nothing works" to cures: A personal account
Pigment Cell Melanoma Res. 2023 Sep 19. doi: 10.1111/pcmr.13133. Online ahead of print.NO ABSTRACTPMID:37726985 | DOI:10.1111/pcmr.13133 (Source: Pigment Cell and Melanoma Research)
Source: Pigment Cell and Melanoma Research - September 20, 2023 Category: Cytology Authors: Meenhard Herlyn Jessie Villanueva Source Type: research

Twenty years of research in melanoma therapy-From "nothing works" to cures: A personal account
Pigment Cell Melanoma Res. 2023 Sep 19. doi: 10.1111/pcmr.13133. Online ahead of print.NO ABSTRACTPMID:37726985 | DOI:10.1111/pcmr.13133 (Source: Pigment Cell and Melanoma Research)
Source: Pigment Cell and Melanoma Research - September 20, 2023 Category: Cytology Authors: Meenhard Herlyn Jessie Villanueva Source Type: research

Twenty years of research in melanoma therapy-From "nothing works" to cures: A personal account
Pigment Cell Melanoma Res. 2023 Sep 19. doi: 10.1111/pcmr.13133. Online ahead of print.NO ABSTRACTPMID:37726985 | DOI:10.1111/pcmr.13133 (Source: Pigment Cell and Melanoma Research)
Source: Pigment Cell and Melanoma Research - September 20, 2023 Category: Cytology Authors: Meenhard Herlyn Jessie Villanueva Source Type: research

Twenty years of research in melanoma therapy-From "nothing works" to cures: A personal account
Pigment Cell Melanoma Res. 2023 Sep 19. doi: 10.1111/pcmr.13133. Online ahead of print.NO ABSTRACTPMID:37726985 | DOI:10.1111/pcmr.13133 (Source: Pigment Cell and Melanoma Research)
Source: Pigment Cell and Melanoma Research - September 20, 2023 Category: Cytology Authors: Meenhard Herlyn Jessie Villanueva Source Type: research

Unsuspected consequences of synonymous and missense variants in OCA2 can be detected in blood cell RNA samples of patients with albinism
In conclusion, blood cell RNA analysis allows testing the potential effect of any OCA2 VUS on transcription products. This should help to elucidate yet unsolved OCA2 patients and improve genetic counseling.PMID:37650133 | DOI:10.1111/pcmr.13123 (Source: Pigment Cell and Melanoma Research)
Source: Pigment Cell and Melanoma Research - August 31, 2023 Category: Cytology Authors: Vincent Michaud Ang èle Sequeira Elina Mercier Eulalie Lasseaux Claudio Plaisant Smail Hadj-Rabia Sandra Whalen Dominique Bonneau Anne Dieux-Coeslier Fanny Morice-Picard Juliette Coursimault Beno ît Arveiler Sophie Javerzat Source Type: research

Unsuspected consequences of synonymous and missense variants in OCA2 can be detected in blood cell RNA samples of patients with albinism
In conclusion, blood cell RNA analysis allows testing the potential effect of any OCA2 VUS on transcription products. This should help to elucidate yet unsolved OCA2 patients and improve genetic counseling.PMID:37650133 | DOI:10.1111/pcmr.13123 (Source: Pigment Cell and Melanoma Research)
Source: Pigment Cell and Melanoma Research - August 31, 2023 Category: Cytology Authors: Vincent Michaud Ang èle Sequeira Elina Mercier Eulalie Lasseaux Claudio Plaisant Smail Hadj-Rabia Sandra Whalen Dominique Bonneau Anne Dieux-Coeslier Fanny Morice-Picard Juliette Coursimault Beno ît Arveiler Sophie Javerzat Source Type: research

Unsuspected consequences of synonymous and missense variants in OCA2 can be detected in blood cell RNA samples of patients with albinism
In conclusion, blood cell RNA analysis allows testing the potential effect of any OCA2 VUS on transcription products. This should help to elucidate yet unsolved OCA2 patients and improve genetic counseling.PMID:37650133 | DOI:10.1111/pcmr.13123 (Source: Pigment Cell and Melanoma Research)
Source: Pigment Cell and Melanoma Research - August 31, 2023 Category: Cytology Authors: Vincent Michaud Ang èle Sequeira Elina Mercier Eulalie Lasseaux Claudio Plaisant Smail Hadj-Rabia Sandra Whalen Dominique Bonneau Anne Dieux-Coeslier Fanny Morice-Picard Juliette Coursimault Beno ît Arveiler Sophie Javerzat Source Type: research

Unsuspected consequences of synonymous and missense variants in OCA2 can be detected in blood cell RNA samples of patients with albinism
In conclusion, blood cell RNA analysis allows testing the potential effect of any OCA2 VUS on transcription products. This should help to elucidate yet unsolved OCA2 patients and improve genetic counseling.PMID:37650133 | DOI:10.1111/pcmr.13123 (Source: Pigment Cell and Melanoma Research)
Source: Pigment Cell and Melanoma Research - August 31, 2023 Category: Cytology Authors: Vincent Michaud Ang èle Sequeira Elina Mercier Eulalie Lasseaux Claudio Plaisant Smail Hadj-Rabia Sandra Whalen Dominique Bonneau Anne Dieux-Coeslier Fanny Morice-Picard Juliette Coursimault Beno ît Arveiler Sophie Javerzat Source Type: research

Unsuspected consequences of synonymous and missense variants in OCA2 can be detected in blood cell RNA samples of patients with albinism
In conclusion, blood cell RNA analysis allows testing the potential effect of any OCA2 VUS on transcription products. This should help to elucidate yet unsolved OCA2 patients and improve genetic counseling.PMID:37650133 | DOI:10.1111/pcmr.13123 (Source: Pigment Cell and Melanoma Research)
Source: Pigment Cell and Melanoma Research - August 31, 2023 Category: Cytology Authors: Vincent Michaud Ang èle Sequeira Elina Mercier Eulalie Lasseaux Claudio Plaisant Smail Hadj-Rabia Sandra Whalen Dominique Bonneau Anne Dieux-Coeslier Fanny Morice-Picard Juliette Coursimault Beno ît Arveiler Sophie Javerzat Source Type: research

Unsuspected consequences of synonymous and missense variants in OCA2 can be detected in blood cell RNA samples of patients with albinism
In conclusion, blood cell RNA analysis allows testing the potential effect of any OCA2 VUS on transcription products. This should help to elucidate yet unsolved OCA2 patients and improve genetic counseling.PMID:37650133 | DOI:10.1111/pcmr.13123 (Source: Pigment Cell and Melanoma Research)
Source: Pigment Cell and Melanoma Research - August 31, 2023 Category: Cytology Authors: Vincent Michaud Ang èle Sequeira Elina Mercier Eulalie Lasseaux Claudio Plaisant Smail Hadj-Rabia Sandra Whalen Dominique Bonneau Anne Dieux-Coeslier Fanny Morice-Picard Juliette Coursimault Beno ît Arveiler Sophie Javerzat Source Type: research