Characterization of PRAME immunohistochemistry reveals lower expression in pediatric melanoma compared to adult melanoma
Pigment Cell Melanoma Res. 2024 Mar 20. doi: 10.1111/pcmr.13167. Online ahead of print.ABSTRACTPediatric melanomas are rare tumors that have clinical and histological differences from adult melanomas. In adult melanoma, the immunohistochemical marker PRAME is increasingly employed as a diagnostic adjunct. PRAME is also under investigation as a target structure for next-generation immunotherapies including T-cell engagers. Little is known about the characteristics of PRAME expression in pediatric melanoma. In this retrospective study, samples from 25 pediatric melanomas were compared with control groups of melanomas in youn...
Source: Pigment Cell and Melanoma Research - March 21, 2024 Category: Cytology Authors: Stephan Forchhammer Valentin Aebischer Daniela Lenders Christian M Seitz Christopher Schroeder Alexandra Liebmann Michael Abele Hannah Wild Ewa Bien Malgorzata Krawczyk Dominik T Schneider Ines B Brecht Lukas Flatz Matthias Hahn Source Type: research
Characterization of PRAME immunohistochemistry reveals lower expression in pediatric melanoma compared to adult melanoma
Pigment Cell Melanoma Res. 2024 Mar 20. doi: 10.1111/pcmr.13167. Online ahead of print.ABSTRACTPediatric melanomas are rare tumors that have clinical and histological differences from adult melanomas. In adult melanoma, the immunohistochemical marker PRAME is increasingly employed as a diagnostic adjunct. PRAME is also under investigation as a target structure for next-generation immunotherapies including T-cell engagers. Little is known about the characteristics of PRAME expression in pediatric melanoma. In this retrospective study, samples from 25 pediatric melanomas were compared with control groups of melanomas in youn...
Source: Pigment Cell and Melanoma Research - March 21, 2024 Category: Cytology Authors: Stephan Forchhammer Valentin Aebischer Daniela Lenders Christian M Seitz Christopher Schroeder Alexandra Liebmann Michael Abele Hannah Wild Ewa Bien Malgorzata Krawczyk Dominik T Schneider Ines B Brecht Lukas Flatz Matthias Hahn Source Type: research
Characterization of PRAME immunohistochemistry reveals lower expression in pediatric melanoma compared to adult melanoma
Pigment Cell Melanoma Res. 2024 Mar 20. doi: 10.1111/pcmr.13167. Online ahead of print.ABSTRACTPediatric melanomas are rare tumors that have clinical and histological differences from adult melanomas. In adult melanoma, the immunohistochemical marker PRAME is increasingly employed as a diagnostic adjunct. PRAME is also under investigation as a target structure for next-generation immunotherapies including T-cell engagers. Little is known about the characteristics of PRAME expression in pediatric melanoma. In this retrospective study, samples from 25 pediatric melanomas were compared with control groups of melanomas in youn...
Source: Pigment Cell and Melanoma Research - March 21, 2024 Category: Cytology Authors: Stephan Forchhammer Valentin Aebischer Daniela Lenders Christian M Seitz Christopher Schroeder Alexandra Liebmann Michael Abele Hannah Wild Ewa Bien Malgorzata Krawczyk Dominik T Schneider Ines B Brecht Lukas Flatz Matthias Hahn Source Type: research
Characterization of PRAME immunohistochemistry reveals lower expression in pediatric melanoma compared to adult melanoma
Pigment Cell Melanoma Res. 2024 Mar 20. doi: 10.1111/pcmr.13167. Online ahead of print.ABSTRACTPediatric melanomas are rare tumors that have clinical and histological differences from adult melanomas. In adult melanoma, the immunohistochemical marker PRAME is increasingly employed as a diagnostic adjunct. PRAME is also under investigation as a target structure for next-generation immunotherapies including T-cell engagers. Little is known about the characteristics of PRAME expression in pediatric melanoma. In this retrospective study, samples from 25 pediatric melanomas were compared with control groups of melanomas in youn...
Source: Pigment Cell and Melanoma Research - March 21, 2024 Category: Cytology Authors: Stephan Forchhammer Valentin Aebischer Daniela Lenders Christian M Seitz Christopher Schroeder Alexandra Liebmann Michael Abele Hannah Wild Ewa Bien Malgorzata Krawczyk Dominik T Schneider Ines B Brecht Lukas Flatz Matthias Hahn Source Type: research
Characterization of PRAME immunohistochemistry reveals lower expression in pediatric melanoma compared to adult melanoma
Pigment Cell Melanoma Res. 2024 Mar 20. doi: 10.1111/pcmr.13167. Online ahead of print.ABSTRACTPediatric melanomas are rare tumors that have clinical and histological differences from adult melanomas. In adult melanoma, the immunohistochemical marker PRAME is increasingly employed as a diagnostic adjunct. PRAME is also under investigation as a target structure for next-generation immunotherapies including T-cell engagers. Little is known about the characteristics of PRAME expression in pediatric melanoma. In this retrospective study, samples from 25 pediatric melanomas were compared with control groups of melanomas in youn...
Source: Pigment Cell and Melanoma Research - March 21, 2024 Category: Cytology Authors: Stephan Forchhammer Valentin Aebischer Daniela Lenders Christian M Seitz Christopher Schroeder Alexandra Liebmann Michael Abele Hannah Wild Ewa Bien Malgorzata Krawczyk Dominik T Schneider Ines B Brecht Lukas Flatz Matthias Hahn Source Type: research
Characterization of PRAME immunohistochemistry reveals lower expression in pediatric melanoma compared to adult melanoma
Pigment Cell Melanoma Res. 2024 Mar 20. doi: 10.1111/pcmr.13167. Online ahead of print.ABSTRACTPediatric melanomas are rare tumors that have clinical and histological differences from adult melanomas. In adult melanoma, the immunohistochemical marker PRAME is increasingly employed as a diagnostic adjunct. PRAME is also under investigation as a target structure for next-generation immunotherapies including T-cell engagers. Little is known about the characteristics of PRAME expression in pediatric melanoma. In this retrospective study, samples from 25 pediatric melanomas were compared with control groups of melanomas in youn...
Source: Pigment Cell and Melanoma Research - March 21, 2024 Category: Cytology Authors: Stephan Forchhammer Valentin Aebischer Daniela Lenders Christian M Seitz Christopher Schroeder Alexandra Liebmann Michael Abele Hannah Wild Ewa Bien Malgorzata Krawczyk Dominik T Schneider Ines B Brecht Lukas Flatz Matthias Hahn Source Type: research
Characterization of PRAME immunohistochemistry reveals lower expression in pediatric melanoma compared to adult melanoma
Pigment Cell Melanoma Res. 2024 Mar 20. doi: 10.1111/pcmr.13167. Online ahead of print.ABSTRACTPediatric melanomas are rare tumors that have clinical and histological differences from adult melanomas. In adult melanoma, the immunohistochemical marker PRAME is increasingly employed as a diagnostic adjunct. PRAME is also under investigation as a target structure for next-generation immunotherapies including T-cell engagers. Little is known about the characteristics of PRAME expression in pediatric melanoma. In this retrospective study, samples from 25 pediatric melanomas were compared with control groups of melanomas in youn...
Source: Pigment Cell and Melanoma Research - March 21, 2024 Category: Cytology Authors: Stephan Forchhammer Valentin Aebischer Daniela Lenders Christian M Seitz Christopher Schroeder Alexandra Liebmann Michael Abele Hannah Wild Ewa Bien Malgorzata Krawczyk Dominik T Schneider Ines B Brecht Lukas Flatz Matthias Hahn Source Type: research
Characterization of PRAME immunohistochemistry reveals lower expression in pediatric melanoma compared to adult melanoma
Pigment Cell Melanoma Res. 2024 Mar 20. doi: 10.1111/pcmr.13167. Online ahead of print.ABSTRACTPediatric melanomas are rare tumors that have clinical and histological differences from adult melanomas. In adult melanoma, the immunohistochemical marker PRAME is increasingly employed as a diagnostic adjunct. PRAME is also under investigation as a target structure for next-generation immunotherapies including T-cell engagers. Little is known about the characteristics of PRAME expression in pediatric melanoma. In this retrospective study, samples from 25 pediatric melanomas were compared with control groups of melanomas in youn...
Source: Pigment Cell and Melanoma Research - March 21, 2024 Category: Cytology Authors: Stephan Forchhammer Valentin Aebischer Daniela Lenders Christian M Seitz Christopher Schroeder Alexandra Liebmann Michael Abele Hannah Wild Ewa Bien Malgorzata Krawczyk Dominik T Schneider Ines B Brecht Lukas Flatz Matthias Hahn Source Type: research
The metabolism of melanin synthesis-From melanocytes to melanoma
In this report we provide an updated review on melanin metabolism, including recent data leveraging new techniques, and technologies in the field of metabolism. We also discuss the many aspects of melanin synthesis that intersect with metabolic pathways known to impact melanoma phenotypes and behavior. By reviewing the metabolism of melanin synthesis, we hope to highlight outstanding questions and opportunities for future research that could improve patient outcomes in pigmentary and oncologic disease settings.PMID:38445351 | DOI:10.1111/pcmr.13165 (Source: Pigment Cell and Melanoma Research)
Source: Pigment Cell and Melanoma Research - March 6, 2024 Category: Cytology Authors: Marelize Snyman Rachel Elizabeth Walsdorf Sophia Nicole Wix Jennifer Gibson Gill Source Type: research
The metabolism of melanin synthesis-From melanocytes to melanoma
In this report we provide an updated review on melanin metabolism, including recent data leveraging new techniques, and technologies in the field of metabolism. We also discuss the many aspects of melanin synthesis that intersect with metabolic pathways known to impact melanoma phenotypes and behavior. By reviewing the metabolism of melanin synthesis, we hope to highlight outstanding questions and opportunities for future research that could improve patient outcomes in pigmentary and oncologic disease settings.PMID:38445351 | DOI:10.1111/pcmr.13165 (Source: Pigment Cell and Melanoma Research)
Source: Pigment Cell and Melanoma Research - March 6, 2024 Category: Cytology Authors: Marelize Snyman Rachel Elizabeth Walsdorf Sophia Nicole Wix Jennifer Gibson Gill Source Type: research
The metabolism of melanin synthesis-From melanocytes to melanoma
In this report we provide an updated review on melanin metabolism, including recent data leveraging new techniques, and technologies in the field of metabolism. We also discuss the many aspects of melanin synthesis that intersect with metabolic pathways known to impact melanoma phenotypes and behavior. By reviewing the metabolism of melanin synthesis, we hope to highlight outstanding questions and opportunities for future research that could improve patient outcomes in pigmentary and oncologic disease settings.PMID:38445351 | DOI:10.1111/pcmr.13165 (Source: Pigment Cell and Melanoma Research)
Source: Pigment Cell and Melanoma Research - March 6, 2024 Category: Cytology Authors: Marelize Snyman Rachel Elizabeth Walsdorf Sophia Nicole Wix Jennifer Gibson Gill Source Type: research
The metabolism of melanin synthesis-From melanocytes to melanoma
In this report we provide an updated review on melanin metabolism, including recent data leveraging new techniques, and technologies in the field of metabolism. We also discuss the many aspects of melanin synthesis that intersect with metabolic pathways known to impact melanoma phenotypes and behavior. By reviewing the metabolism of melanin synthesis, we hope to highlight outstanding questions and opportunities for future research that could improve patient outcomes in pigmentary and oncologic disease settings.PMID:38445351 | DOI:10.1111/pcmr.13165 (Source: Pigment Cell and Melanoma Research)
Source: Pigment Cell and Melanoma Research - March 6, 2024 Category: Cytology Authors: Marelize Snyman Rachel Elizabeth Walsdorf Sophia Nicole Wix Jennifer Gibson Gill Source Type: research
The metabolism of melanin synthesis-From melanocytes to melanoma
In this report we provide an updated review on melanin metabolism, including recent data leveraging new techniques, and technologies in the field of metabolism. We also discuss the many aspects of melanin synthesis that intersect with metabolic pathways known to impact melanoma phenotypes and behavior. By reviewing the metabolism of melanin synthesis, we hope to highlight outstanding questions and opportunities for future research that could improve patient outcomes in pigmentary and oncologic disease settings.PMID:38445351 | DOI:10.1111/pcmr.13165 (Source: Pigment Cell and Melanoma Research)
Source: Pigment Cell and Melanoma Research - March 6, 2024 Category: Cytology Authors: Marelize Snyman Rachel Elizabeth Walsdorf Sophia Nicole Wix Jennifer Gibson Gill Source Type: research
The metabolism of melanin synthesis-From melanocytes to melanoma
In this report we provide an updated review on melanin metabolism, including recent data leveraging new techniques, and technologies in the field of metabolism. We also discuss the many aspects of melanin synthesis that intersect with metabolic pathways known to impact melanoma phenotypes and behavior. By reviewing the metabolism of melanin synthesis, we hope to highlight outstanding questions and opportunities for future research that could improve patient outcomes in pigmentary and oncologic disease settings.PMID:38445351 | DOI:10.1111/pcmr.13165 (Source: Pigment Cell and Melanoma Research)
Source: Pigment Cell and Melanoma Research - March 6, 2024 Category: Cytology Authors: Marelize Snyman Rachel Elizabeth Walsdorf Sophia Nicole Wix Jennifer Gibson Gill Source Type: research
The metabolism of melanin synthesis-From melanocytes to melanoma
In this report we provide an updated review on melanin metabolism, including recent data leveraging new techniques, and technologies in the field of metabolism. We also discuss the many aspects of melanin synthesis that intersect with metabolic pathways known to impact melanoma phenotypes and behavior. By reviewing the metabolism of melanin synthesis, we hope to highlight outstanding questions and opportunities for future research that could improve patient outcomes in pigmentary and oncologic disease settings.PMID:38445351 | DOI:10.1111/pcmr.13165 (Source: Pigment Cell and Melanoma Research)
Source: Pigment Cell and Melanoma Research - March 6, 2024 Category: Cytology Authors: Marelize Snyman Rachel Elizabeth Walsdorf Sophia Nicole Wix Jennifer Gibson Gill Source Type: research
