Dose –Response Relationship of Photobiomodulation Therapy on Matrix Metalloproteinase in Healing Dynamics of Diabetic Neuropathic Ulcers—An in vivo Study
Photobiomodulation therapy (PBMT) for the healing of diabetic neuropathic ulcer: Induction of neuropathy was done by the sciatic crush injury method. An excisional wound of depth 0.1 cm and area 2 cm2 was created on the neuropathy-induced leg in all the animals. Experimental group animals were irradiated with PBMT of Scanning LASER 655 nm and probe LASER 808 nm. Control group animals were kept un-irradiated. AbstractIndividuals with diabetic foot ulcers have overlapped the inflammatory, proliferative and remodeling phase, making the tissue vulnerable to delayed healing responses. We aimed to establish the dose ...
Source: Photochemistry and Photobiology - January 16, 2023 Category: Science Authors: Gagana Karkada,
G Arun Maiya,
Praveen Arany,
Mohandas Rao KG,
Shalini Adiga,
Shobha U. Kamath Tags: Research Article Source Type: research
Heat ‐Killed Lactobacillus rhamnosus ATCC 7469 Improved UVB‐Induced Photoaging Via Antiwrinkle and Antimelanogenesis Impacts
In conclusion, our findings suggest that RL could reduce photoaging caused by UVBvia antiwrinkle and antimelanogenesis properties and may be a potential antiphotoaging beneficial component, which is applied in the cosmetic industry. (Source: Photochemistry and Photobiology)
Source: Photochemistry and Photobiology - January 12, 2023 Category: Science Authors: Xiaofang Zhang,
Jing Xu,
Mingzhu Ma,
Yadong Zhao,
Yan Song,
Bin Zheng,
Zhengshun Wen,
Miao Gong,
Lingting Meng Tags: Research Article Source Type: research
Photo ‐controlled Release of Carbendazim from Photocaged Molecule
This study aimed to covalently link MBC and 6-nitropiperonyl alcohol (NP) to synthesize photocaged molecule NP-MBC. The photodegradation test showed that NP-MBC could effectively release MBC under ultraviolet light. The antifungal activity of NP-MBC showed significant difference againstRhizoctonia solani,Sclerotinia sclerotiorun andFusarium graminearum before and after irradiation, and the effects on mycelial morphology are different. The hyphae morphology ofR. solani andF. graminearum changed significantly, and mycelia were severely damaged. The hyphae surface of former was swollen and broken, and the latter was collapsed...
Source: Photochemistry and Photobiology - January 11, 2023 Category: Science Authors: Xiaoyi Dai,
Zhong Li,
Xusheng Shao Tags: Research Article Source Type: research
Critical PDT Theory VI: Detection of Reactive Oxygen Species: Trials and Errors
(Source: Photochemistry and Photobiology)
Source: Photochemistry and Photobiology - January 10, 2023 Category: Science Authors: David Kessel Tags: Correspondence Source Type: research
Acclimation Response of Green Microalgae Chlorella Sorokiniana to 2,3 ′,4,4′,6‐Pentachlorobiphenyl
A strong negative effect of the toxicant 2,3 ′,4,4′,6-pentachlorobiphenyl (PCB-119) on Chlorella sorokiniana cells was observed at PCB concentration of 0.05 μg mL−1. Photosynthetic activity measured in cell suspension was fully inhibited at 24 h, whereas recovery of photosynthetic activity was observed at 96 h. The study of the distribution of individual cells in culture revealed the existence of 2–3% of cells retaining high photosynthetic activity at 96 h, when almost all cells were dead. These cells enabled treated cultures to resume growth after prolonged incubation in fresh medium. AbstractThe effec...
Source: Photochemistry and Photobiology - January 9, 2023 Category: Science Authors: Alena A. Volgusheva,
Daria A. Todorenko,
Ivan V. Konyukhov,
Elena N. Voronova,
Sergey I. Pogosyan,
Tatyana Yu Plyusnina,
Sergey S. Khruschev,
Taras K. Antal Tags: Research Article Source Type: research
D ‐A‐D‐based Unsymmetrical Thiosquaraine Dye for the Dye‐Sensitized Solar Cells
Alkyl group-wrapped thiosquaraine dye exhibited better light harvesting property than its corresponding oxo-counterpart,that is, squaraine dyes. However, formation of triplet state caused insufficient charge injection process which led to decreased dye-sensitized solar cell device performance. AbstractIn dye-sensitized solar cell, modulating the electronic properties of the sensitizer by varying the donor, π-spacer, acceptor and anchoring groups help optimizing the structure of the dye for better device performance. Here, a donor–acceptor–donor-based unsymmetrical thiosquaraine sensitizer (SQ5S) has been designed and ...
Source: Photochemistry and Photobiology - January 9, 2023 Category: Science Authors: Avinash P. Jadhav,
Ambarish Kumar Singh,
Ashakiran Maibam,
Sailaja Krishnamurty,
Kothandam Krishnamoorthy,
Jayaraj Nithyanandhan Tags: Special Issue Research Article Source Type: research
Engineered Ferritin with Eu3+ as a Bright Nanovector: A Photoluminescence Study
In this study, among lanthanides, we selected europium for its red emission that allows to reduce overlap with tissue auto-fluorescence. Steady state emission measurements and time-resolved emission spectroscopy have been employed to investigate the interaction between the HFt-LBT and the Eu3+ ions. This allowed us to identify the Eu3+ energy states involved in the process and to pave the way for the future use of HFt-LBT Eu3+ complex in theranostics. (Source: Photochemistry and Photobiology)
Source: Photochemistry and Photobiology - January 4, 2023 Category: Science Authors: Luisa Affatigato,
Alice Sciortino,
Giuseppe Sancataldo,
Alessio Incocciati,
Roberta Piacentini,
Alessandra Bonamore,
Marco Cannas,
Fabrizio Messina,
Mariano Licciardi,
Valeria Militello Tags: Research Article Source Type: research
Ultraviolet Light, Unfolded Protein Response, and Autophagy
AbstractThe endoplasmic reticulum (ER) plays an important role in the regulation of protein synthesis. Alterations in the folding capacity of the ER induce stress, which activates three ER sensors that mediate the unfolded protein response (UPR). Components of the pathways regulated by these sensors have been shown to regulate autophagy. The last corresponds to a mechanism of self-eating and recycling important for proper cell maintenance. Ultraviolet radiation (UV) is an external damaging stimulus that is known for inducing oxidative stress, and DNA, lipid, and protein damage. Many controversies exist regarding the role o...
Source: Photochemistry and Photobiology - January 3, 2023 Category: Science Authors: Ver ónica A. Bahamondes Lorca,
Shiyong Wu Tags: Special Issue Invited Review Source Type: research
Heat ‐killed Lactobacillus Rhamnosus ATCC 7469 Improved UVB‐Induced Photoaging via Anti‐Wrinkle and Anti‐Melanogenesis Impacts
In conclusion, our findings suggest that RL could reduce photoaging caused by UVB via anti-wrinkle and anti-melanogenesis properties and may be a potential anti-photoaging beneficial component, which is applied in the cosmetic industry. (Source: Photochemistry and Photobiology)
Source: Photochemistry and Photobiology - January 2, 2023 Category: Science Authors: Xiaofang Zhang,
Jing Xu,
Mingzhu Ma,
Yadong Zhao,
Yan Song,
Bin Zheng,
Zhengshun Wen,
Miao Gong,
Lingting Meng Tags: Research Article Source Type: research
Nanoformulation of Lipophilic Osmium Photosensitizers in Liposomes and Micelles as a General Strategy for Improving Reproducibility and Reducing Quenching
AbstractNanoformulation of an osmium photosensitizer within liposomes and micelles is used to improve the water-solubility of this highly lipophilic molecule. This highlight report describes a recent paper by Cameron, Obaid, and McFarland on this topic and discusses the context for this report. Nanoformulation has been explored as a strategy before, but this represents the first usage of this strategy with highly potent metal-based photosensitizers having phototherapeutic indices (PIs) in excess of 104. The nanoformulation strategy is effective due to reducing aggregation and self-quenching of the photosensitizer molecules...
Source: Photochemistry and Photobiology - January 2, 2023 Category: Science Authors: Elizabeth T. Papish Tags: Highlight Article Source Type: research
D ‐A‐D Based Unsymmetrical Thiosquaraine Dye for the Dye‐Sensitized Solar Cells
AbstractIn dye-sensitized solar cell, modulating the electronic properties of the sensitizer by varying the donor, π-spacer, acceptor, and anchoring groups help optimizing the structure of the dye for better device performance. Here, a donor-acceptor-donor based unsymmetrical thiosquaraine sensitizer (SQ5S) has been designed and synthesized. Photophysical, electrochemical, theoretical, and photovoltaic characterizations ofSQ5S dye have been compared with its oxygen analog,SQ5. The incorporation of the sulfur atom in the acceptor unit ofSQ5S dye showed an intense peak at 688 nm, which was 38 nm of red-shifted and showed th...
Source: Photochemistry and Photobiology - December 30, 2022 Category: Science Authors: Avinash P. Jadhav,
Ambarish Kumar Singh,
Ashakiran Maibam,
Sailaja Krishnamurty,
Kothandam Krishnamoorthy,
Nithyanandhan Jayaraj Tags: Special Issue Research Article Source Type: research
Synthesis, Characterization and Photocleavage of Bis ‐decyl Pteroic Acid: A Folate Derivative with Affinity to Biomembranes
A new lipophilic folate derivative namelybis-decyl-Pte was synthesized, structurally and photophysically characterized. Decylation of pteroic acid (Pte) occurred at ketoO4 and at thep-aminobenzoic acid carboxylic acid group, pointing to a kinetically-controlled process based on results from DFT calculations. The photochemistry ofbis-decyl-Pte was investigated detecting a photocleavage attributed to a hydrolysis of the methylene bridge, as observed for Pte and folic acid. Moreover, asbis-decyl-Pte is able to interact with lipid membranes, efforts would be focused on investigating the photosensitizing properties of this comp...
Source: Photochemistry and Photobiology - December 30, 2022 Category: Science Authors: Jos é Luis Fonseca,
María José Sosa,
Gabriela Petroselli,
Rosa Erra‐Balsells,
Matías I. Quindt,
Sergio M. Bonesi,
Alexander Greer,
Edyta M. Greer,
Andrés H. Thomas,
Mariana Vignoni Tags: Special Issue Research Article Source Type: research
Practical Aspects in the Study of Biological Photosensitization Including Reaction Mechanisms and Product Analyses: A Do's and Don ’ts Guide
AbstractThe interaction of light with natural matter leads to a plethora of photosensitized reactions. These reactions cause the degradation of biomolecules, such as DNA, lipids, proteins, being therefore detrimental to the living organisms, or they can also be beneficial by allowing the treatment of several diseases by photomedicine. Based on the molecular mechanistic understanding of the photosensitization reactions, we propose to classify them in four processes: oxygen-dependent (type I and type II processes) and oxygen-independent [triplet-triplet energy transfer (TTET) and photoadduct formation]. In here, these proces...
Source: Photochemistry and Photobiology - December 28, 2022 Category: Science Authors: Maur ício S. Baptista,
Jean Cadet,
Alexander Greer,
Andrés H. Thomas Tags: Special Issue Invited Review Source Type: research
Establishing a Robust and Reliable Response from a Potent Osmium ‐Based Photosensitizer Via Lipid Nanoformulation
PEG-modified DPPC liposomes reduce aggregation and interassay variability in phototoxic response for an osmium-based photosensitizer. AbstractOsmium (Os) based photosensitizers (PSs) are a unique class of nontetrapyrrolic metal-containing PSs that absorb red light. We recently reported a highly potent Os(II) PS,rac-[Os(phen)2(IP-4T)](Cl)2, referred to as ML18J03 herein, with light EC50 values as low as 20 pm. ML18J03 also exhibits low dark toxicity and submicromolar light EC50 values in hypoxia in some cell lines. However, owing to its longer oligothiophene chain, ML18J03 is not completely water soluble and forms 1 –2 ...
Source: Photochemistry and Photobiology - December 26, 2022 Category: Science Authors: Houston D. Cole,
Menitte Eroy,
John A. Roque,
Ge Shi,
Mina Guirguis,
John Fakhry,
Colin G. Cameron,
Girgis Obaid,
Sherri A. McFarland Tags: Special Issue Research Article Source Type: research
Serial Cross ‐Sectional Observations of Sun‐protective Behaviours at an Annual Outdoor Motorsport Event in Tropical Queensland, Australia
AbstractSkin cancer, the most prevalent cancer in Caucasians residing at low latitudes, can primarily be prevented by avoiding over-exposure to sunlight. Serial cross-sectional observations were conducted at an outdoor motorsport event held in Townsville, Queensland each July (Southern winter) to determine whether sun-protection habits changed over time. Most (71.1%) of the 1,337 attendees observed (97.6% lightly-pigmented skin, 64.0% male) wore a hat (any style shading the face), while few (18.5%) wore three-quarter or full-length sleeves. While hat-wearing rates (any style) were similar in 2009 (326, 72.6%) and 2013 (625...
Source: Photochemistry and Photobiology - December 26, 2022 Category: Science Authors: Ben Dexter,
Annika Smith,
Rachel King,
Nathan J. Downs,
Catherine Jane Nikles,
Alfio V. Parisi,
Yik ‐Hong Ho,
Simone Lee Harrison Tags: Research Article Source Type: research
