Modification of traditional composite nonwovens with stable storage of light absorption transients and photodynamic antibacterial effect
In this study, a photodynamic and high-efficiency antimicrobial protective material was prepared by grafting bis benzophenone-structured 4,4-terephthaloyl diphthalic anhydride (TDPA) photosensitizer, and antimicrobial agent chlorogenic acid (CA) onto spunbond-meltblown-spunbond (SMS) membranes. The charging rates for·OH and H2O2 were 6377.89 and 913.52 μg/g/h. The light absorption transients structural storage remained above 69% for 1 month. High electrical capacity remained after seven cycles indicating its rechargeability and recyclability. The SMS/TDPA/CA membrane has excellent bactericidal performance when under i...
Source: Photochemistry and Photobiology - March 26, 2024 Category: Science Authors: Ting ‐Ting Li,
Bing‐Bing Shou,
Lu Yang,
Hai‐Tao Ren,
Xian‐Jin Hu,
Jia‐Horng Lin,
Tao Cai,
Ching‐Wen Lou Tags: RESEARCH ARTICLE Source Type: research
Compound collagen peptide powder improves skin photoaging by reducing oxidative stress and activating TGF ‐β1/Smad pathway
The objective of this study was to investigate the efficacy of CCPP and its molecular mechanism. CCPP had a low molecular weight, facilitating its efficient absorption, and was abundant in amino acids, total polyphenols, and total flavonoids. The results of in vivo studies demonstrated that CCPP exhibited significant efficacy in reducing skin wrinkles, enhancing the contents of water and oil in the skin, and ameliorating histopathological alterations in mice. The results of in vitro studies demonstrated that CCPP effectively mitigated photoaging in hum an skin fibroblasts by attenuating oxidative stress and promoting ex...
Source: Photochemistry and Photobiology - March 20, 2024 Category: Science Authors: Kaien Guo,
Linxin Zheng,
Xin Zeng,
Guangchun Huang,
Lingling Meng,
Yuting Yin Tags: RESEARCH ARTICLE Source Type: research
Issue Information
(Source: Photochemistry and Photobiology)
Source: Photochemistry and Photobiology - March 19, 2024 Category: Science Tags: Issue Information Source Type: research
Special issue on nucleic acid photophysics
(Source: Photochemistry and Photobiology)
Source: Photochemistry and Photobiology - March 19, 2024 Category: Science Authors: Carlos E. Crespo ‐Hernández Tags: EDITORIAL Source Type: research
Highways and detours in the realm of photodynamic therapy for cancer control
Critical elements of photodynamic therapy are a photosensitizing agent, light at a wavelength corresponding to an absorbance band of the agent, and sufficient oxygenation to create a cytotoxic concentration of reactive oxygen species. Other factors may promote efficacy, but these are critical. (Source: Photochemistry and Photobiology)
Source: Photochemistry and Photobiology - March 16, 2024 Category: Science Authors: David Kessel Tags: CORRESPONDENCE Source Type: research
Metal ‐semiconductor heterojunction accelerates the plasmonically powered photoregeneration of biological cofactors
The integration of titanium dioxide with gold nanoparticles led to a 12-fold enhancement in the plasmonically driven regeneration of nicotinamide cofactor, by following a less-explored light-independent pathway. AbstractPhotocatalysis with plasmonic nanoparticles (NPs) is emerging as an attractive strategy to make and break chemical bonds. However, the fast relaxation dynamics of the photoexcited charge carriers in plasmonic NPs often result in poor yields. The separation and extraction of photoexcited hot-charge carriers should be faster than the thermalization process to overcome the limitation of poor yield. This demand...
Source: Photochemistry and Photobiology - March 15, 2024 Category: Science Authors: Namitha Deepak,
Vanshika Jain,
Pramod P. Pillai Tags: SPECIAL ISSUE RESEARCH ARTICLE Source Type: research
Effectiveness of lapatinib for enhancing 5 ‐aminolevulinic acid‐mediated protoporphyrin IX fluorescence and photodynamic therapy in human cancer cell lines with varied ABCG2 activities
Lapatinib, a repurposed ABCG2 inhibitor, dose-dependently enhanced ALA-induced PpIX fluorescence and PDT response in a panel of human tumor cell lines with varied ABCG2 activities and protein levels. Tumor cell lines with lower ABCG2 activities were more sensitive to lapatinib for PpIX/PDT enhancement. Abstract5-Aminolevulinic acid (ALA) is a prodrug for protoporphyrin IX (PpIX)-mediated photodynamic therapy (PDT) and fluorescence-guided tumor surgery. We previously reported that lapatinib, a repurposed ABCG2 inhibitor, enhanced ALA-induced PpIX fluorescence and PDT by blocking ABCG2-mediated PpIX efflux. In the present st...
Source: Photochemistry and Photobiology - March 14, 2024 Category: Science Authors: Richard Howley,
Jordyn Olsen,
Bin Chen Tags: SPECIAL ISSUE RESEARCH ARTICLE Source Type: research
Effect of 980 nm photobiomodulation delivered by a handpiece with Gaussian vs. Flat‐Top profiles on proliferation and differentiation of buccal fat pad stem cells
In this work, we measured the proliferation and differentiation of mesenchymal stem cell of buccal fat pad treated with Gaussian and Flat-Top profiles of 980 nm diode laser in photobiomodulation mode. Each irradiation group was allocated into three subgroups based on the number of irradiation (one, two-, and three-times irradiation). Cell proliferation was evaluated by 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide, and cell viability w as verified by Annexin V test. Osteogenic differentiation of mesenchymal stem cell of buccal fat pad and their mineralization pattern were assessed by real-time polymerase...
Source: Photochemistry and Photobiology - March 11, 2024 Category: Science Authors: Ali Homayouni,
Maryam Rezaie Rad,
Hamidreza Barikani,
Nasim Chiniforush,
Solmaz Akbari Tags: RESEARCH ARTICLE Source Type: research
The REV ‐ERB antagonist SR8278 modulates keratinocyte viability in response to UVA and UVB radiation
The cryptochrome (CRY) inhibitor KS15 and REV-ERB antagonist SR8278 are small-molecule modulators of the circadian clock, in which the core circadian protein BMAL1 plays a critical role in regulating the expression of clock-controlled genes (CCGs). Here, we investigated the potential use of these compounds in UV photoprotection in keratinocytes. AbstractThe nucleotide excision repair (NER) system removes UV photoproducts from genomic DNA and is controlled by the circadian clock. Given that small-molecule compounds have been developed to target various clock proteins, we examined whether the cryptochrome inhibitor KS15 and ...
Source: Photochemistry and Photobiology - March 9, 2024 Category: Science Authors: William Cvammen,
Michael G. Kemp Tags: RESEARCH ARTICLE Source Type: research
Molecular rotors of naphthalimide and benzodithiophene as effective solvent polarity probes, temperature sensors, and for g ‐C3N4 sensitization
In this study, we have synthesized two novel rotor molecules,NBN1 andNBN2, by incorporating benzodithiophene (BDT) as the donor core and naphthalic anhydride/naphthalimide (NA/NI) moieties as acceptors using Pd-catalyzed Stille coupling reactions. These molecules exhibited distinct charge transfer (CT) behavior in both their absorption and emission spectra and displayed prominent emission solvatochromism. Notably,NBN1 exhibited better CT properties among the two molecules. Moreover, these A –D–A molecular rotors demonstrated remarkable sensitivities of their emission spectra toward solvent polarities and temperatures. ...
Source: Photochemistry and Photobiology - March 9, 2024 Category: Science Authors: Anita Kumari,
Sushil Sharma,
Sanchita Sengupta Tags: SPECIAL ISSUE RESEARCH ARTICLE Source Type: research
Potential of using medicinal plant extracts as photosensitizers for antimicrobial photodynamic therapy
In this study, we used commercially available preparations (Calendulae officinalis floridis extract,Chamomillae recutitae floridis extract,Achillea millefolii herbae extract;Hypericum perforatum extract;Eucalyptus viminalis folia extract) as photosensitizers for inactivation of gram-negative (Pseudomonas aeruginosa) and gram-positive (Staphylococcus aureus) bacteria. Spectral-luminescent analysis has shown that the major chromophores are of chlorophyll (mainly chlorophylla andb) and hypericin nature. The extracts are efficient generators of singlet oxygen with quantum yield (γΔ) from 0.40 to 0.64 (reference compound, met...
Source: Photochemistry and Photobiology - March 8, 2024 Category: Science Authors: Aliaksandr V. Mikulich,
Vitaly Yu. Plavskii,
Antonina I. Tretyakova,
Raman K. Nahorny,
Andrey N. Sobchuk,
Natalia V. Dudchik,
Olga A. Emeliyanova,
Anastasia I. Zhabrouskaya,
Ludmila G. Plavskaya,
Tatsiana S. Ananich,
Olga N. Dudinova,
Ihar A. L Tags: RESEARCH ARTICLE Source Type: research
Application of TNB in dual photo ‐controlled release of phenamacril, imidacloprid, and imidacloprid synergist
TNB could realize dual photo-controlled release of pesticide molecules at time and space. TNB will be an innovative photosensitive protective group for light-dependent application of agrochemicals in the future. AbstractPesticides can improve crops' yield and quality, but unreasonable applications of pesticides lead to waste of pesticides which are further accumulated in the environment and threaten human health. Developing the release of controlled drugs can improve the utilization rate of pesticides. Among these methods, light-controlled release is a new technology of controlled release, which can realize spatiotemporal ...
Source: Photochemistry and Photobiology - March 7, 2024 Category: Science Authors: Qi Yin,
Wen Fu,
Xinyue Hu,
Zhiping Xu,
Zhong Li,
Xusheng Shao Tags: RESEARCH ARTICLE Source Type: research
Photoprotective effect of topical treatment with Lopezia racemosa extract against deleterious UVB irradiation effects in the skin of hairless mice
Lopezia racemosa is one of the most important weeds of Mexican origin. The methanolic extract of this plant (MELR) is mainly composed of 5 glycosides derived from quercetin. MELR has ability to scavenge radicals such as DPPH and ABTS. In addition, it has absorption in the UVA region. In challenge experiments, MELR generate photoprotection in bacteria and in CD-1 et/et mice exposed to UVR acutely. The concentration of IL-12 is higher in unprotected mice than in protected ones. MELR possesses sunscreens properties. AbstractLopezia racemosa is known as a “mosquito flower or perlilla.” It is commonly found in corn crops. I...
Source: Photochemistry and Photobiology - March 6, 2024 Category: Science Authors: Nolasco Ontiveros Erick,
Espinosa Gonz ález Adriana Montserrat,
Estrella Parra Edgar Antonio,
Serrano Parrales Rocío,
López Urrutia Eduardo,
García Castillo Verónica,
Rodríguez‐Sosa Miriam,
Juárez‐Avelar Imelda,
Benítez Flores José de Tags: RESEARCH ARTICLE Source Type: research
The acid sphingomyelinase inhibitor imipramine enhances the release of UV photoproduct ‐containing DNA in small extracellular vesicles in UVB‐irradiated human skin
Using cultured HaCaT cells in vitro, discarded human surgical skin ex vivo, and skin biopsies from human subjects in vivo, the association of UV photoproduct-containing DNA with small extracellular vesicles is shown to be increased by treatment with the acid sphingomyelinase inhibitor imipramine. These results indicate that a pharmacological inhibitor of large extracellular vesicle release is associated with elevated release of DNA damaged by UV radiation. AbstractNucleic acids, lipids, and other cell components can be found within different types of extracellular vesicles (EVs), which include apoptotic bodies (ABs), l...
Source: Photochemistry and Photobiology - March 4, 2024 Category: Science Authors: M. Alexandra Carpenter,
Anita Thyagarajan,
Madison Owens,
Risha Annamraju,
Christina B. Borchers,
Jeffrey B. Travers,
Michael G. Kemp Tags: RESEARCH ARTICLE Source Type: research
Mitochondrial targeting improves the selectivity of singlet ‐oxygen cleavable prodrugs in NMIBC treatment
Due to higher membrane potential (MMP) of the cancer cells mitochondria ( −220 mV) compared to the MMP in healthy cells (−140 mV), cationic prodrugs are an excellent choice to achieve selectivity. With our singlet oxygen activatable rhodamine linked paclitaxel (Rh-L-PTX) and rhodamine linked SN-38 (Rh-L-SN-38) prodrugs, we could achieve 2–3 times selectivity in vitro and as much as 34 times selectivity in vivo over non-tumor cells. AbstractMitochondria play an essential role in cancer treatment by providing apoptotic signals. Hexyl aminolevulinate, an FDA-approved diagnosis for non-muscle invasive bladder canc...
Source: Photochemistry and Photobiology - March 4, 2024 Category: Science Authors: Kazi Md Mahabubur Rahman,
Ganesh Bist,
Soniya Kumbham,
Barbara A. Foster,
Sukyung Woo,
Youngjae You Tags: SPECIAL ISSUE RESEARCH ARTICLE Source Type: research
