Shine, Shine, Ruthenium Caged Drug
AbstractThis is a highlight on the paper by Bonnet and coworkers:A Lock-and-Kill Anticancer Photoactivated Chemotherapy Agent. which constitutes an important step toward establishing photoactivated chemotherapy (PACT) as a widespread tool to treat different health issues, specially tumors. PACT can be a useful technique to deliver already tested drugs, where the effect of the desired molecule is directed only to its target after light irradiation, even in the cases in which it is difficult to achieve a precise delivery in the desired organ or tissue. Ruthenium-polipyridyl caged-compounds are near ideal devices to deliver a...
Source: Photochemistry and Photobiology - December 23, 2022 Category: Science Authors: Roberto Etchenique,
Oscar Filevich Tags: Highlight Article Source Type: research
Acclimation Response of Green Microalgae Chlorella sorokiniana to 2,3',4,4',6 ‐Pentachlorobiphenyl
AbstractThe effect of the toxicant 2,3',4,4',6-pentachlorobiphenyl (PCB-119) on the growth, chlorophyll content, and PSII activity ofC. sorokiniana cells was investigated. A strong negative effect of the toxicant was observed at PCB concentration of 0.05 μg mL–1, when culture growth ceased, chlorophyll strongly bleached, and cell death occurred. The use of original highly sensitive fluorimeter to measure three types of high-resolution chlorophyll fluorescence kinetics allowed us to detect an initial dramatic decrease in the activity of primary photosynthetic reactions, followed by their almost complete recovery at the e...
Source: Photochemistry and Photobiology - December 23, 2022 Category: Science Authors: A. A. Volgusheva,
D. A. Todorenko,
I. V. Konyukhov,
E. N. Voronova,
S. I. Pogosyan,
T. Yu. Plyusnina,
S. S. Khruschev,
T. K. Antal Tags: ResearchArticle Source Type: research
Dye Degradation and Sulfur Oxidation of Methyl Orange and Thiophenol via Newly Designed Nanocomposite GQDs/NiSe ‐NiO Photocatalyst Under Homemade LED Light
AbstractPhotocatalytic processes triggered by graphene-based photocatalysts under solar light have sparked interest as a new sort of instrument for solar chemical synthesis. Herein we investigated self-assembled graphene quantum dots (GQDs)/NiSe-NiO composite photocatalyst for organic transformation as well as dye degradation. The synthesized GQDs/NiSe-NiO composite photocatalyst has an excellent suitable band gap, high molar extinction coefficient, low toxicity, and chemical/thermal stability. The GQDs/NiSe-NiO composite photocatalyst emerges as a new standard for sulfur oxidation and dye degradation reactions under homem...
Source: Photochemistry and Photobiology - December 21, 2022 Category: Science Authors: Shivangi Srivastava,
Rajesh K Yadav,
P. P. Pande,
Satyam Singh,
Surabhi Chaubey,
Pooja Singh,
Sarvesh Kumar Gupta,
Shivani Gupta,
Tae Wu Kim,
Dhanesh Tiwary Tags: Research Article Source Type: research
980 nm Photobiomodulation Promotes Osteo/Odontogenic Differentiation of the Stem Cells from Human Exfoliated Deciduous Teeth Via the Cross talk Between BMP/Smad and Wnt/β‐Catenin Signaling Pathways
In conclusion, PBM induces the osteo/odontogenic differentiation of SHEDs through cross talk between BMP/Smad and Wnt/β-catenin signaling pathways. (Source: Photochemistry and Photobiology)
Source: Photochemistry and Photobiology - December 20, 2022 Category: Science Authors: Ziting Wang,
Tian Tian,
Leyi Chen,
Chuhan Zhang,
Xiao Zheng,
Ni Zhong,
Buling Wu,
Wen'an Xu Tags: Research Article Source Type: research
Toxic Interaction Between Solar Radiation and Cigarette Smoke on Primary Human Keratinocytes
The objective of this study was to evaluate and understand the synergistic harmful effects of cigarette smoke and solar rays on human primary keratinocytes. The keratinocytes were exposed to cigarette smoke extract (CSE) and then irradiated with a solar simulator light (SSL). The viability, as determined by measuring metabolic activity of skin cells, and the levels of global reactive oxygen species (ROS) were evaluated after exposure to CSE and SSL. The combination of 3% CSE with 29 kJ/m2 UVA caused a decrease of 81% in cell viability, while with 10% to 20% CSE, the cell viability was null. This phototoxicity was accompani...
Source: Photochemistry and Photobiology - December 20, 2022 Category: Science Authors: Alexe Grenier,
Mathieu C Morissette,
Patrick J Rochette,
Roxane Pouliot Tags: Research Article Source Type: research
Self ‐reported Side‐effects of Ultraviolet‐C Disinfection Devices
This study explores self-reported side-effects of UV-C devices by collating five waves of UK consumer survey data from April 2020-December 2021 (N= 26,864). 30%-46% of owners report a side-effect after using a device claiming to emit UV-C. However, detailed analysis of Wave 4 data (N = 309) highlights inconsistencies between reported and plausible side-effect(s) associated with skin or eye exposure from UV-C devices. Alternative explanations are considered, namely that the reported side-effect(s) were psychosomatic or misattributed to direct exposure of UV-C radiation. Data regarding awareness of warnings about device s...
Source: Photochemistry and Photobiology - December 19, 2022 Category: Science Authors: Zo ë Adams,
Christos Bechlivanidis,
Magda Osman,
John O’Hagan,
Dzhordzhio Naldzhiev Tags: Research Article Source Type: research
Field Study and Evaluation of KrCl* Far UV ‐C Device Capability for Inactivation of Phi6 Bacteriophage
This study illustrates the applicability and deployment of Far UV-C for pathogen reduction and can help in decision making for implementation of Far UV-C for disinfection in human occupied environments. (Source: Photochemistry and Photobiology)
Source: Photochemistry and Photobiology - December 19, 2022 Category: Science Authors: Saba Seyedi,
Ben Ma,
Megan Groves,
Hal King,
Karl G. Linden Tags: Research Article Source Type: research
Nanocaging Rose Bengal to Inhibit Aggregation and Enhance Photo ‐induced Oxygen Consumption†
Host –guest complexation of cyclodextrin macrocycles and Rose Bengal (RB) inhibits the aggregation of RB and enhances the rates of photobleaching and triplet oxygen consumption. AbstractPhotosensitized crosslinking of proteins in tissues has many medical applications including sealing wounds, strengthening tissues, and beneficially altering tissue properties. Rose Bengal (RB) is used most frequently as the photosensitizer but is not as efficient as would be desired for broad utilization in medicine. Aggregation of RB, at the high concentrations used for medical treatments, decreases the yield of singlet oxygen, which med...
Source: Photochemistry and Photobiology - December 19, 2022 Category: Science Authors: Constanza Alvarez ‐Lopez,
Daniela Cavazos‐Elizondo,
Belinda Heyne,
Irene E. Kochevar,
Alan Aguirre‐Soto Tags: Special Issue Research Article Source Type: research
Spectral Mismatch Effect of Ultraviolet Radiometers in Actual UV ‐C Measurement
AbstractThe management of radiant exposure to ultraviolet (UV) radiation, especially in the wavelength range from 100nm to 280 nm (i.e., UV-C), is important for virus inactivation or photobiological safety. Recently, many commercial UV radiometers have been used to measure UV-C irradiance for industrial and public applications. The accuracy of the four types of commercial UV radiometers was investigated by comparing the reference irradiance values obtained from the spectral irradiance standard. It was found that the displayed values of the UV radiometers have discrepancies, such that the measured value can be more than twi...
Source: Photochemistry and Photobiology - December 19, 2022 Category: Science Authors: Yuki Iwasa,
Kenichi Kinoshita,
Hiroshi Shitomi Tags: Research Article Source Type: research
The Modulation of Blue ‐Light‐Induced Inflammation, Intracellular Lipid Secretion, and Oxidative Stress in Sebocytes with Cannabidiol
AbstractLight-induced skin damage leads to cellular or molecular dysfunction, thus potentially causing different skin issues (e.g., skin aging, seborrheic dermatitis and pigmentation). Blue light, a potent visible light that was previously adopted for promoting skin regeneration, draws considerable concerns in the past several years due to their potential damage to the skins. In this work, we investigated the roles of blue light in skewing the functions of sebocytes – the major cells that compose the sebaceous gland – an important “active” neuro-immuno-endocrine organ in maintaining skin functions. For therapeutica...
Source: Photochemistry and Photobiology - December 17, 2022 Category: Science Authors: Yanran Wei,
Tan Tang,
Jitao Liu,
Siyi Yu,
Huo Tong,
Peipei Zhang Tags: Research Article Source Type: research
Evaluation of Antifungal Activity and Potential Application as Fluorescent Probes of Indolenine and Benzo[E]Indole ‐Based Squarylium Dyes
AbstractThe antifungal performance and the possible use as fluorescent probes of a series of squarylium dyes derived from indolenine and benzo[e]indole previously synthesized was evaluated. Some photophysical properties were performed in ethanol and phosphate buffer, and the type of aggregates form in phosphate buffer was analyzed. Using the 1,3-diphenylisobenzofuran assay, a qualitative assessment of the capacity of dyes to produce singlet oxygen after irradiation was performed. Regarding the antifungal activity, this was studied through a broth microdilution assay usingSaccharomyces cerevisiae PYCC 4072 as a biological m...
Source: Photochemistry and Photobiology - December 16, 2022 Category: Science Authors: Vanessa S. D. Gomes,
Jo ão C. C. Ferreira,
Renato E. Boto,
Paulo Almeida,
José R. Fernandes,
Maria João Sousa,
Lucinda V. Reis,
M. S. T. Gonçalves Tags: Research Article Source Type: research
Exposed Body Surface Area —A Determinate for UV Radiant Energy in Human UV Exposure Studies
In this paper, knowledge on body shape and methods of calculating the body surface area (BSA) are summarized. BSA and body shape differ significantly between different populations and both change during life. We propose formulas for BSA that consider height, weight, gender, ethnicity, age and body shape. As the exposed BSA depends on clothing, an approach is presented which aims to calculate the size of body parts released by real garments. This work enables future researchers to quantify the exposed BSA and received radiant energy by best matching their study population and consequently investigate risks caused by solar U...
Source: Photochemistry and Photobiology - December 13, 2022 Category: Science Authors: Alois W. Schmalwieser,
Susanne S. Schmalwieser Tags: Invited Review Source Type: research
Binding Properties Characterization of Cr(phen)33+ and Ru(phen)32+ Complexes with Human Lactoferrin
AbstractThis work presents research about [Cr(phen)3]3+ and [Ru(phen)3]2+ interaction with human Lactoferrin (HLf), a key carrier protein of ferric cations. The photochemical and photophysical properties of [Cr(phen)3]3+ and [Ru(phen)3]2+ have been widely studied in the last decades due to their potential use as photosensitizers in photodynamic therapy (PDT). The behavior between the complexes and the protein was studied employing UV-visible absorption, fluorescence emission, and circular dichroism spectroscopic techniques. It was found that both complexes bind to HLf with a large binding constant (Kb): 9.46x104 for the ch...
Source: Photochemistry and Photobiology - December 12, 2022 Category: Science Authors: Pablo Facundo Garcia,
Santiago N. Saez Torillo,
Angel Anzani,
Gerardo Arg üello,
Maxi A. Burgos Paci Tags: Research Article Source Type: research
Engineered Ferritin with Eu3+ as a Bright Nanovector: A Photoluminescence Study
In this study, among lanthanides, we selected europium for its red emission that allows to reduce overlap with tissue auto-fluorescence. Steady state emission measurements and time-resolved emission spectroscopy have been employed to investigate the interaction between the HFt-LBT and the Eu3+ ions. This allowed us to identify the Eu3+ energy states involved in the process and to pave the way for the future use of HFt-LBT Eu3+ complex in theranostics. (Source: Photochemistry and Photobiology)
Source: Photochemistry and Photobiology - December 10, 2022 Category: Science Authors: Luisa Affatigato,
Alice Sciortino,
Giuseppe Sancataldo,
Alessio Incocciati,
Roberta Piacentini,
Alessandra Bonamore,
Marco Cannas,
Fabrizio Messina,
Mariano Licciardi,
Valeria Militello Tags: Research Article Source Type: research
Protective Effect of Orbitides from Linseed (Linum usitatissimum L.) against Ultraviolet B ‐induced Photoaging in Zebrafish
In conclusion, RLOs has strong photoprotective effects and potential to be used as antiphotoaging ingredients. (Source: Photochemistry and Photobiology)
Source: Photochemistry and Photobiology - December 9, 2022 Category: Science Authors: Yu Zhang,
Dekun Cheng,
Zhangtie Wang,
Yiwen Guo,
Ming Chang,
Ruijie Liu Tags: Research Article Source Type: research
