Assessing Agreement between Frequency-Specific Chirp Auditory Steady-State Response and Pure Tone Audiometry in Adults by Intraclass Correlation Coefficient
Conclusion: In this study, we have confirmed good to excellent correlation between chirp-ASSR and PTA in threshold estimation for adults with and without hearing loss. The degree of correlations is higher for participants with hearing loss and for measurements at high frequencies. However, significant systematic difference and large limits of agreement between the 2 methods have been found. These findings show that chirp-ASSR can be treated as a supplementary method to PTA when evaluating the hearing level, but the 2 methods are not interchangeable due to their systematic difference and large limits of agreement.ORL (Source: ORL)
Source: ORL - May 12, 2021 Category: ENT & OMF Source Type: research
Patient Experiences of Postinfectious Olfactory Dysfunction
Conclusion: There appears to be a need to encourage greater use of guidelines for olfactory disorders amongst medical practitioners and also to develop more effective treatments for patients with PIOD, where there is clearly an unmet need.ORL (Source: ORL)
Source: ORL - May 10, 2021 Category: ENT & OMF Source Type: research
Neuroprotective Effect of Brimonidine against Facial Nerve Crush Injury in Rats via Suppressing GFAP/PAF Activation and Neuroinflammation
Conclusions: Brimonidine could promote the recovery of facial nerve crush injury in rats via suppressing of GFAP/PAF activation and neuroinflammation and increasing neurotrophic factors. Brimonidine may be apromising candidate agent for the treatment of facial nerve injury.ORL (Source: ORL)
Source: ORL - May 7, 2021 Category: ENT & OMF Source Type: research
Efficacy of Selective Vidian Neurectomy for Allergic Rhinitis Combined with Chronic Rhinosinusitis
Conclusion: Endoscopic selective vidian neurectomy is an effective and safe technique for the management of moderate to severe persistent ARwCRSwNP.ORL (Source: ORL)
Source: ORL - May 5, 2021 Category: ENT & OMF Source Type: research
Dynamic Study of Oesophageal Function during Phonation: Simple but Effective
We describe the new use of a barium bolus as a diagnostic tool for identifying neopharynx disorders. Appropriately selected patients with pharynx-oesophageal segment disorders could benefit from a neurotoxin-blocking treatment to improve oesophageal speech.ORL (Source: ORL)
Source: ORL - May 5, 2021 Category: ENT & OMF Source Type: research
Adult Transglottic Haemangioma with Upper Airway Obstruction: Preservation of Airway and Voice
Adult laryngeal haemangioma is normally seen in the supraglottic or glottic region. Transglottic haemangioma is unusual, and treatment with primary endolaryngeal surgical excision may lead to undesirable bleeding and poor voice outcomes. A 25-year-old female presented with hoarseness and progressive upper airway obstruction symptoms. Videoendoscopy showed haemangioma involving all unilateral subunits of the larynx obstructing half of the subglottis. The transglottic haemangioma was treated with endolaryngeal ethanol injection with prior tracheostomy under local anaesthesia. Endolaryngeal laser surgery was performed later o...
Source: ORL - May 5, 2021 Category: ENT & OMF Source Type: research
Pemphigus Vulgaris and Bullous Pemphigoid of the Upper Aerodigestive Tract: A Review Article and Novel Approaches to Management
Background: Autoimmune bullous diseases are rare conditions characterized by blistering of the skin and mucous membranes. The 2 commonest forms are pemphigus vulgaris and bullous pemphigoid. The oral cavity or oropharynx may be the initial site of presentation or often the only site involved.Summary: These conditions are often misdiagnosed or overlooked leading to poorer patient outcomes. Due to the chronic nature of these conditions and the systemic effects of treatment, there is a significant associated morbidity and mortality. As such, an understanding of the fundamentals of autoimmune bullous diseases is vital to those...
Source: ORL - April 26, 2021 Category: ENT & OMF Source Type: research
Distinct Patterns of Tissue Remodeling and Their Prognostic Role in Chronic Rhinosinusitis
Conclusions: Tissue eosinophilia was commonly associated with BM thickening and stromal edema. Subepithelial gland proliferation predicted a poor surgical prognosis in CRS. These findings imply that tissue remodeling provides additional information not only on the CRS endotype but also on the postsurgical prognosis.ORL (Source: ORL)
Source: ORL - April 14, 2021 Category: ENT & OMF Source Type: research
Thyroid Dysfunction in M énière’s Disease: A Comprehensive Review
Conclusions: Despite a potential correlation in the medical literature between thyroid disorders and MD, there is currently no definitive causal relationship. Although most of the present medical literature focuses on autoimmunity, dysregulated thyroid hormone levels may also be implicated in the association of MD with thyroid disorders.ORL (Source: ORL)
Source: ORL - April 14, 2021 Category: ENT & OMF Source Type: research
Long Noncoding RNA NEAT1: A Potential Biomarker in the Progression of Laryngeal Squamous Cell Carcinoma
Conclusion: Together, these results suggested that NEAT1 involved in the progress of LSCC and might act as a tumor oncogenic gene. This study provides a potential new marker and target for gene therapy in the treatment of LSCC.ORL (Source: ORL)
Source: ORL - April 8, 2021 Category: ENT & OMF Source Type: research
Sphenoid Sinus: Pneumatization and Septation Patterns in a Hispanic Population
Conclusion: Differences regarding anatomical variants and septations of the SS were observed in our study when compared with findings reported in other ethnic groups. Preoperative assessment of the anatomical variants of the SS in Mexican patients is imperative to select the most optimal surgical approach and prevent iatrogenic injuries to related neurovascular structures.ORL (Source: ORL)
Source: ORL - April 1, 2021 Category: ENT & OMF Source Type: research
Pediatric Malignant Mandibular Tumors: Personal Experience and Literature Options Discussion
Conclusions: Free flaps mandibular reconstruction in children needs to be better assessed and proximal fibular epiphyseal free flap indication might deserve further studies. Osteochondral grafts find indication for lateral defects, 50 –55 mm in maximum length and located in the mandibular ramus, without massive teeth or soft tissue defect. Condyle involvement does not represent an absolute contraindication to rib graft use.ORL (Source: ORL)
Source: ORL - March 31, 2021 Category: ENT & OMF Source Type: research
Sustained Chemosensory Dysfunction during the COVID-19 Pandemic
Conclusion: Rates of improvement and recovery of chemosensory function decreased after 2 –4 months after initial chemosensory loss, possibly indicating that prolonged and perhaps permanent chemosensory loss may be a complication of SARS-CoV-2 infections. High subjective severity of CD may worsen the prognosis for improvement and recovery of chemosensory function.ORL (Source: ORL)
Source: ORL - March 31, 2021 Category: ENT & OMF Source Type: research
Cochlear Implantation in Chronic Otitis Media with and without Cholesteatoma: Surgical Considerations and Auditory Outcomes
Conclusion: Postoperative complications like device failure and skin breakdown are increased in cases of COM compared to standard CI surgeries. However, that increase is not associated with staging the surgeries, presence or absence of cholesteatoma, and type of ear surgery performed. It is advocated to close the external ear canal and eustachian tube without mastoid obliteration in the presence of a radical mastoidectomy cavity, which will decrease the postoperative complication rates and allow for radiological follow-up with computed tomography for the possibility of cholesteatoma recurrence. The auditory benefits of CI ...
Source: ORL - March 30, 2021 Category: ENT & OMF Source Type: research
Augmented Reality with HoloLens ® in Parotid Tumor Surgery: A Prospective Feasibility Study
Conclusion: This pilot study offers a first proof of concept of the clinical feasibility of the HoloLens for parotid tumor surgery. Workflow is not affected, but additional information is provided. The surgical performance could become safer through the navigation-like application of reality-fused 3D holograms, and it improves ergonomics without compromising sterility. Superimposition of the 3D holograms with the surgical field was possible, but further invention is necessary to improve the accuracy.ORL (Source: ORL)
Source: ORL - March 30, 2021 Category: ENT & OMF Source Type: research
