De novo Splice Site Mutation of the < b > < i > CHD7 < /i > < /b > Gene in a Chinese Patient with Typical CHARGE Syndrome
Conclusion: The present study functionally characterized the novel c.3523-2A#x3e;G variant inCHD7, providing further confirmatory evidence that it is associated with CS.ORL (Source: ORL)
Source: ORL - January 25, 2022 Category: ENT & OMF Source Type: research

Malaysian Version of the Sniffin ’ Sticks Identification Smell Test: Cutoff Points of Hyposmia
Conclusion: Our study found that the cutoff points of the identification smell test for hyposmia were lower than those of other studies. It is important to use these cutoff points in our population to establish the correct integrity of olfaction function in the clinic setting and in future research.ORL (Source: ORL)
Source: ORL - January 25, 2022 Category: ENT & OMF Source Type: research

Machine Learning Algorithms as a Computer-Assisted Decision Tool for Oral Cancer Prognosis and Management Decisions: A Systematic Review
Conclusions: ML has the potential to significantly advance research in the field of OCSCC. Advantages are related to the use and training of ML models because of their capability to continue training continuously when more data become available. Future ML research will allow us to improve and democratize the application of algorithms to improve the prediction of cancer prognosis and its management worldwide.ORL (Source: ORL)
Source: ORL - January 12, 2022 Category: ENT & OMF Source Type: research

High Mobility Group Box-1 Protein and Interleukin 33 Expression in Allergic Rhinitis
Conclusions: The expression of HMGB1 and IL-33 were both increased in AR. HMGB1 and IL-33 may have a close relationship in AR.ORL (Source: ORL)
Source: ORL - January 3, 2022 Category: ENT & OMF Source Type: research

Incidence of Head and Neck Cancers before and after 9/11 in New York City and New York State
Conclusions: In NYS, OP cancer and thyroid cancer rates increased significantly during the study period. The rate of thyroid cancer was higher in women. The rate of combined HNC increased significantly after 9/11 compared to before 9/11; however, in a subset analysis of all HNC patients excluding thyroid cancer, the rate decreased significantly prior to 9/11 and then nonsignificantly increased afterward. This suggests that the increase in thyroid cancer accounts for the increase in combined HNC in NYS. The impact of 9/11 on rates of HNC requires further research.ORL (Source: ORL)
Source: ORL - December 27, 2021 Category: ENT & OMF Source Type: research

Efficacy of Endoscopic Posterior Nasal Neurectomy in Treating Eosinophilic Chronic Rhinosinusitis
Conclusions: FESS combined with PNN suppresses edema symptoms, which might significantly decrease the surgical recurrence rate of ECRS in the long term.ORL (Source: ORL)
Source: ORL - December 20, 2021 Category: ENT & OMF Source Type: research

Cortical Atrophy, White Matter Lesions, and Bulb Configuration in Patients with Idiopathic Olfactory Loss and Other Causes of Olfactory Loss
Conclusion: We recommend that structural MRI with an OB sequence is included in the diagnostic evaluation of olfactory loss with suspected congenital and post-traumatic aetiology and should be considered in idiopathic olfactory loss with suspected central aetiology (e.g., tumour).ORL (Source: ORL)
Source: ORL - December 8, 2021 Category: ENT & OMF Source Type: research

Unilateral Choanal Atresia: Indications of Long-Term Olfactory Deficits and Volumetric Brain Changes Postsurgically
Conclusions: This pilot study indicates that persistent olfactory deficits and volumetric brain changes are present in patients with unilateral choanal atresia.ORL (Source: ORL)
Source: ORL - November 26, 2021 Category: ENT & OMF Source Type: research

Contents Vol. 83, 2021
ORL 2021;83:I –VI (Source: ORL)
Source: ORL - November 25, 2021 Category: ENT & OMF Source Type: research

Acknowledgement to Reviewers
ORL 2021;83:483 –484 (Source: ORL)
Source: ORL - November 25, 2021 Category: ENT & OMF Source Type: research

Endoscopic Inferior Meatal Antrostomy for Antrochoanal Polyps: A Long-Term Follow-Up
Conclusions: EIMA prevents violation of the ostiomeatal complex. It provides access to the anteroinferior aspect of the maxillary sinus and should be considered as an alternative to EMMA in patients with ACPs.ORL (Source: ORL)
Source: ORL - November 8, 2021 Category: ENT & OMF Source Type: research

Perfusion-Decellularized Larynx as a Natural 3D Scaffold in a Rabbit Model
Conclusion: Our perfusion decellularization protocol is feasible and reproducible to produce a 3-dimensional whole laryngeal ECM scaffold in a rabbit.ORL (Source: ORL)
Source: ORL - November 4, 2021 Category: ENT & OMF Source Type: research

Transcriptome Analysis Identified 2 New lncRNAs Associated with the Metastasis of Papillary Thyroid Carcinoma
Conclusion: Our findings preliminarily reveal the molecular mechanisms for PTMC metastasis, which will provide vital reference for subsequent studies about the genetic basis and molecular targeted therapy for PTMC metastasis.ORL (Source: ORL)
Source: ORL - October 14, 2021 Category: ENT & OMF Source Type: research

Effects of Dental Factors on Fungal Sinusitis
Conclusion: The rates of tooth extraction were significantly higher in the FMS and CRS groups compared to the normal sinus group. In addition, of the 3 conditions, FMS was related to EDT, and CRS was related to ALs.ORL (Source: ORL)
Source: ORL - October 6, 2021 Category: ENT & OMF Source Type: research

Necessity of Intraoperative Level IIA Lymph Node Dissection in Patients with Carotid Body Tumors: A Retrospective Study of 126 Cases
Conclusion: Intraoperative dissection of level IIA lymph nodes around the tumor in CBT patients can help improve the diagnosis and prognosis of MCBTs without causing additional cranial nerve injury.ORL (Source: ORL)
Source: ORL - October 5, 2021 Category: ENT & OMF Source Type: research