Initial Presentation of Granulomatosis with Polyangiitis as Progressive Skull Base Osteomyelitis
A healthy man in his 30s presented with a 2-week history of severe bitemporal pain and pressure. He was initially treated for presumed acute rhinosinusitis, but his symptoms continued to worsen and underwent endoscopic sinus surgery at an outside community facility. He developed left abducens nerve palsy postoperatively, and magnetic resonance imaging (MRI) demonstrated evidence of extensive skull base osteomyelitis. He was initiated on intravenous (IV) broad-spectrum antibiotics but was subsequently found to have prostatic and submandibular sterile fluid collections. The patient subsequently developed new right abducens a...
Source: ORL - September 30, 2021 Category: ENT & OMF Source Type: research
Treatment Modality and Second Primary Tumors of the Head and Neck
Conclusion: Treatment modality used for head and neck cancer does not seem to be associated with the occurrence of SPTs.ORL (Source: ORL)
Source: ORL - September 29, 2021 Category: ENT & OMF Source Type: research
Impact of Masks on Speech Recognition in Adult Patients with and without Hearing Loss
Conclusion: Our results suggest that masks significantly decrease word recognition, and this effect is exacerbated with N95 masks, particularly in patients with hearing loss. As masks are essential to allow for safe patient-physician interactions, it is imperative that clinicians are aware they may create a barrier to effective communication.ORL (Source: ORL)
Source: ORL - September 28, 2021 Category: ENT & OMF Source Type: research
Beyond VOTE: The New Frontier of Drug-Induced Sleep Endoscopy
Alternatives to positive airway pressure therapy, including surgery, represent an important area of research. Specifically, predictors of response to surgical therapy remain underdeveloped. Drug-induced sleep endoscopy (DISE) holds promise as a diagnostic tool to identify patient-specific causes of airway collapse. Herein, we present a novel, standardized approach which combines anatomic and physiologic measurements during DISE. Our DISE platform measures airflow, airway compliance, airway collapsibility, and structural drivers of collapse. Taken together, these inputs provide a comprehensive framework to further inform th...
Source: ORL - September 27, 2021 Category: ENT & OMF Source Type: research
The Expression and Regulation of Na < sup > + < /sup > -K < sup > + < /sup > -ATPase in Nasal Epithelial Cells of Chronic Rhinosinusitis with Nasal Polyps
Conclusion: NKA and AQP5 expressions were decreased in CRSwNP. NKA in HNECs could be suppressed by SEB, LPS, IFN- γ, IL-4, IL-13, and IL-1β. Impairment of NKA may contribute to the genesis and development of CRSwNP via inducing AQP5 downregulation and edema.ORL (Source: ORL)
Source: ORL - September 22, 2021 Category: ENT & OMF Source Type: research
Comparison of Olfactory Cleft Width and Volumes in Patients with COVID-19 Anosmia and COVID-19 Cases Without Anosmia
Conclusion: Patients with COVID-19-related OD had larger olfactory cleft width and volumes than those without OD in this study. Total TDI score was found to be inversely correlated with cleft width and volume.ORL (Source: ORL)
Source: ORL - September 21, 2021 Category: ENT & OMF Source Type: research
Phonosurgery Training in Human Larynx Preserved with Thiel ’s Embalming Method
Conclusions: The human larynges embalmed with Thiel ’s method maintain the pliability of the vocal cords, thus representing a unique model to practice and reproduce training for endolaryngeal procedures without the risks of contamination, anatomical variation, or rigidity of other models.ORL (Source: ORL)
Source: ORL - September 16, 2021 Category: ENT & OMF Source Type: research
Computed Tomography Analysis of the Anterosuperior Portion of the Bulla Lamella in Chinese Subjects and Its Surgical Significance in Endoscopic Frontal Sinusotomy
Conclusions: There was an association between the presence of SBFC and the occurrence of FS. Extension of the anterosuperior portion of the bulla lamella into the frontal sinus obstructed the drainage pathway posteriorly. Understanding the anatomy may help surgeons thoroughly dissect the bulla lamella.ORL (Source: ORL)
Source: ORL - September 10, 2021 Category: ENT & OMF Source Type: research
Efficacy of Sublingual Immunotherapy in Allergic Rhinitis Children during Coronavirus Disease 2019
Conclusion: Our results suggest that continuous HDM exposure reduced the effectiveness of SLIT, whereas effective reduction of HDM levels by frequent bed cleaning will be helpful during the SLIT treatment.ORL (Source: ORL)
Source: ORL - September 10, 2021 Category: ENT & OMF Source Type: research
Cochlear Implantation in Inner Ear Malformations: Considerations Related to Surgical Complications and Communication Skills
Conclusion: It is possible to improve communication skills with CIs in patients with IEMs despite the variations in postoperative performances. Patients with EVA, incomplete partition type 2, and cochlear hypoplasia type 2 were the best performers in terms of auditory-verbal skills. Patients with IEMs scored poorly compared to patients with normal cochleae. CSF leak (gusher or oozing) was the most common complication during surgery, which is highly likely in cases of incomplete partition type 3.ORL (Source: ORL)
Source: ORL - September 9, 2021 Category: ENT & OMF Source Type: research
Therapeutic Potential of Human Nasal Inferior Turbinate-Derived Stem Cells: Microarray Analysis of Multilineage Differentiation
Conclusion: Considering overall results, hNTSCs-specific genetic information may promote further studies on intracellular mechanisms defining key features of these cells.ORL (Source: ORL)
Source: ORL - September 6, 2021 Category: ENT & OMF Source Type: research
A Prospective Study of the Effect of Tinnitus Sound Matching Degree on the Efficacy of Customized Sound Therapy in Patients with Chronic Tinnitus
Conclusions: Both tinnitus sound matching and nonmatching of the customized sound therapy brought a significant effect to tinnitus participants. Our study also suggests that THI and HADS-A scores of those with tinnitus matching participants improved markedly as compared to those of nonmatching participants, and the customized sound therapy effect is negatively correlated with the severity of hearing loss.ORL (Source: ORL)
Source: ORL - September 3, 2021 Category: ENT & OMF Source Type: research
Awake Rhinology Surgery in Response to the COVID-19 Pandemic in Europe
Conclusion: Awake surgery potentially provides quicker access to routine rhinology surgery in the post-COVID-19 recovery phase, ensuring patients are treated in a timely matter, thereby avoiding higher downstream costs, and improving outcomes.ORL (Source: ORL)
Source: ORL - August 31, 2021 Category: ENT & OMF Source Type: research
Survey of the Use of Diffusion-Weighted Imaging for Cholesteatoma in the United Kingdom
Conclusions and Significance: DWMRI has a well-defined role in the follow-up of patients after cholesteatoma surgery, and those primary cases of cholesteatoma where the diagnosis is in question. The use of DWMRI for cholesteatoma is variable across the UK, but there are certain clinical scenarios where there is not enough awareness regarding the benefits of imaging (such as petrous apex cases of cholesteatoma).ORL (Source: ORL)
Source: ORL - August 27, 2021 Category: ENT & OMF Source Type: research
Sequential Bilateral Cochlear Implantation in a Child with Severe External, Middle, and Inner Ear Malformations: Surgical Considerations and Practical Aspects
We report herein the case of a 2-year-old girl who presented with profound bilateral sensorineural hearing loss, congenital aural atresia, microtia, and inner ear malformations. High-resolution computed tomography revealed poor development of the bilateral middle ear spaces, absence of the incus and stapes, aberrant courses of facial nerves, aplastic lateral semicircular canals, and covered round windows. With intraoperative imaging assistance, sequential bilateral CI was performed using a transmastoid approach with no complication. We propose that CI is feasible in patients with severe external and middle ear malformation...
Source: ORL - August 25, 2021 Category: ENT & OMF Source Type: research
