Risk of Ischemic Stroke after an Inpatient Hospitalization for Transient Ischemic Attack in the United States
Conclusions: Patients hospitalized for TIA have a lower risk of ischemic stroke compared to that reported in the studies based on the emergency room and/or outpatient clinic evaluation. Among these patients, those with cardiovascular comorbidities remain at a higher risk of readmission due to ischemic stroke despite undergoing an inpatient evaluation and should therefore be the target for future preventive strategies.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - December 1, 2020 Category: Epidemiology Source Type: research
Joinpoint Regression Analysis of Trends in Multiple Sclerosis Incidence in Kuwait: 1980 –2019
Conclusions: From 1980 to 2010, Kuwait has an overall significantly increasing trend in MS ASIRs followed by a nonsignificant declining drift in the ensuing period. The increasing trend in MS risk appeared to be driven by increased risk among Kuwaiti females younger than 40 years. The underlying factors modulating MS risk in Kuwait need further studies.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - November 11, 2020 Category: Epidemiology Source Type: research
The Epidemiology of Noise Sensitivity in New Zealand
Conclusion: There is evidence of social determinants of noise sensitivity, including social position and residential factors.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - November 11, 2020 Category: Epidemiology Source Type: research
Stroke Patients with Atrial Fibrillation Treated with Oral Anticoagulants: Comparison of the Population-Based Stroke Registry of Dijon and the French National Health Databases
Conclusion: If administrative health databases can be a useful tool to study the epidemiology of anticoagulated AF in stroke patients, population-based stroke registries as the Dijon Stroke Registry remain essential to fully study the epidemiology of strokes with anticoagulated AF.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - October 28, 2020 Category: Epidemiology Source Type: research
Early-Life Factors and Risk of Multiple Sclerosis: An MR-EWAS
Conclusions: We introduced the MR-EWAS, a 2-step approach that is more powerful compared with the hypothesis-free MR approach under certain scenarios, to test potential causal signals. Our comprehensive assessment of early-life risk factors of MS highlighted a potential causal role of early menarche and elevated childhood BMI for risk of MS.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - October 23, 2020 Category: Epidemiology Source Type: research
Implications of the Use of Algorithmic Diagnoses or Medicare Claims to Ascertain Dementia
Conclusions: Absolute estimates of dementia prevalence should rely on samples with formal dementia ascertainment. The use of multiple algorithms is recommended for risk factor studies when formal dementia ascertainment is not available.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - October 19, 2020 Category: Epidemiology Source Type: research
National Stroke Registry Programme in India for Surveillance and Research: Design and Methodology
The objectives of the National Stroke Registry Programme (NSRP), India, are to generate reliable data on the incidence of first-ever stroke events in defined populations through a population-based stroke registry (PBSR) and to describe the patterns of care and outcomes of patients with stroke in different treatment settings through a hospital-based stroke registry (HBSR). Continuous systematic collection on a standardized format of diagnostic, treatment, and outcome information on stroke events in persons of defined population (PBSR) and those who attend hospitals (HBSR) is conducted through active data abstraction from re...
Source: Neuroepidemiology - October 19, 2020 Category: Epidemiology Source Type: research
Pattern Recognition to Objectively Differentiate the Etiology of Cognitive Decline: Analysis of the Impact of Stroke and Alzheimer ’s Disease
This study examined the amount of variance in age-related cognitive change that is accounted for by AD and stroke using a novel pattern re cognition protocol.Method: Secondary analyses of data collected for the Health and Retirement Study (N = 17,579) were used to objectively characterize patterns of cognitive decline associated with AD and stroke. The rate of decline in episodic memory and orientation was the outcome of interest, while algorithms indicative of AD and stroke pathology were the predictors of interest.Results: The average age of the sample was 67.54 ± 10.45 years at baseline, and they completed, on average,...
Source: Neuroepidemiology - October 5, 2020 Category: Epidemiology Source Type: research
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Source: Neuroepidemiology - September 29, 2020 Category: Epidemiology Source Type: research
Ethnic Differences in Access to Stroke Reperfusion Therapy in Northern New Zealand
Conclusions: This study has shown equitable access to acute stroke reperfusion therapies and largely similar outcomes in different ethnic groups in northern New Zealand.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - September 21, 2020 Category: Epidemiology Source Type: research
Representation of Older Latinxs in Cohort Studies at the Rush Alzheimer ’s Disease Center
We describe an a nnual clinical evaluation that assesses risk factors for Alzheimer’s dementia among older adults without known dementia at enrollment. As all RADC cohort studies offer brain donation as a part of research participation, we discuss our approach to brain donation and subsequent participant decision- making among older Latinxs. We also summarize baseline characteristics of older Latinxs across the 5 RADC cohort studies in relation to the baseline characteristics of non-Latinx blacks and non-Latinx whites. Finally, we outline challenges and considerations as well as potential next steps in cognit ive aging r...
Source: Neuroepidemiology - September 9, 2020 Category: Epidemiology Source Type: research
Frequency and Timing of Endovascular Therapy in Acute Stroke Patients: A Population-Based Analysis Using the Bremen Stroke Register
Conclusions: Approximately 12% of all ischemic stroke patients received ET, and the incidence of ET was 17 (95% CI: 14 –21) cases per 100,000 person-years. However, despite being a high-volume center, the absolute number of stroke procedures per month was low, and many patients were treated during nonwork hours.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - September 9, 2020 Category: Epidemiology Source Type: research
Risk of Dementia in Diabetic Patients with Hyperglycemic Crisis: A Nationwide Taiwanese Population-Based Cohort Study
Conclusions: HCE increased the risk of dementia in diabetic patients aged 45 –64 years. Dementia was predicted by ≥3 HCEs. Prevention of recurrent HCE, control of comorbidities, and close follow-up of cognitive decline and dementia are suggested in patients with HCE.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - August 25, 2020 Category: Epidemiology Source Type: research
Association of Coronavirus Disease 2019 and Stroke: A Rising Concern
The severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) causes the coronavirus disease 2019 (COVID-19). It quickly became pandemic, and so did a new concern about COVID-19 infections increasing the risk for cerebrovascular diseases. There is an association between COVID-19 illness in people and acute stroke. Several chemical, mechanical, and/or inflammatory central nervous system pathologies are proposed to explain how this viral infection might induce acute cerebrovascular disease. Timely available evaluation and/or intervention is imperative for patients with concerns about acute cerebrovascular issues.Neuroepid...
Source: Neuroepidemiology - August 13, 2020 Category: Epidemiology Source Type: research
Parkinson ’s Disease-Related Motor and Nonmotor Symptoms in the Lancaster Amish
Discussion: These data neither support a markedly higher PD prevalence in the older Lancaster Amish nor do they show dramatically higher motor and/or selected nonmotor symptoms than the general population. Future studies that employ more rigorous procedures for case identification and PD-specific preclinical symptoms/tests are needed to determine the potential differences and similarities among different Amish populations and between Amish and non-Amish populations.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - July 31, 2020 Category: Epidemiology Source Type: research
