Reliability of Self-report Data on Age of Onset in Essential Tremor: Data from a Prospective, Longitudinal Cohort
Background: Essential tremor (ET) is a highly prevalent neurological disease. Age of onset can occur anytime between childhood and advanced age. Tremor generally starts insidiously. Age of onset is a particularly important data item in clinical and epidemiological research. In general, these data are self-reported by ET cases. A fundamental question is whether ET cases reliably report their age of onset.
Methods: In this prospective, epidemiological study of 125 ET cases, self-reported age of onset data were collected at regular 18 months intervals over four time points.
Results: The correlation between self-reported age...
Source: Neuroepidemiology - November 1, 2022 Category: Epidemiology Source Type: research
Predictive Value of Pediatric Stroke Diagnoses in Administrative Data: A Systematic Literature Review
Conclusion
Caution is recommended in the use and interpretation of non-validated administrative data for pediatric stroke. Data on the PPV and sensitivity of pediatric stroke diagnoses in administrative data remain limited and are only available from high-income countri es. (Source: Neuroepidemiology)
Source: Neuroepidemiology - November 1, 2022 Category: Epidemiology Source Type: research
Demographics of Cauda Equina Syndrome: A Population-Based Incidence Study
Conclusion: CES occurred more commonly in females and in those between 30 and 49 years and had no association with socioeconomic status. The incidence of CES in Scotland is at least four times higher than previous European estimates of 0.3 –0.6 per 100,000 population per year. Incidence varies with clinical diagnostic criteria. To enable comparison of rates of CES across populations, we recommend using standardized clinical and radiological criteria and standardization for population structure.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - October 31, 2022 Category: Epidemiology Source Type: research
Demographics of Cauda Equina Syndrome: A Population Based Incidence Study
Conclusion
CES occurred more commonly in females and in those between 30-49 years, and had no association with socioeconomic status. The incidence of CES in Scotland is at least four times higher than previous European estimates of 0.3-0.6 per 100,000 p opulation per year. Incidence varies with clinical diagnostic criteria. To enable comparison of rates of CES across populations, we recommend using standardised clinical and radiological criteria and standardisation for population structure. (Source: Neuroepidemiology)
Source: Neuroepidemiology - October 31, 2022 Category: Epidemiology Source Type: research
Impact of Smoking on Functional Prognosis after Ischemic Stroke according to Deprivation: A Prospective Cohort Study
Conclusion: The effect of smoking on functional prognosis after ischemic stroke varied according to deprivation status, with poorer outcomes observed in nondeprived patients.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - October 27, 2022 Category: Epidemiology Source Type: research
Burden of Parkinson Disease in China, 1990 –2019: Findings From the 2019 Global Burden of Disease Study
Conclusion: Although ASDR and age-standardized DALY rates for PD have been declining, the burden of PD still needs attention, as the total numbers have increased over the period. Generally, the greater burden from PD was in males. A sound health system with services tailored to PD continues to be required in the future. (Source: Neuroepidemiology)
Source: Neuroepidemiology - October 26, 2022 Category: Epidemiology Source Type: research
Case Fatality Rates of Subarachnoid Hemorrhage Are Decreasing with Substantial between-Country Variation: A Systematic Review of Population-Based Studies between 1980 and 2020
Conclusion: Short-term SAH CFRs seem to have declined since 1980. Time trends of SAH CFRs can still be identified for only a few populations, and high-quality data are scarce. Whether the observed decline relates to changes in risk factors, treatment outcomes or diagnostics remains to be studied.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - October 25, 2022 Category: Epidemiology Source Type: research
Primary malignant brain tumors following systemic malignancies: a population-based analysis
CONCLUSION: Our study provides a comprehensive analysis of clinical data and the SIRs of patients with primary malignant brain tumors afterwards other systemic malignancies. Genetic relationships might play a key role in subsequent malignant brain tumor origin. Our data provide directions for future studies exploring the hidden associations between systemic malignancies and primary malignant brain tumors. (Source: Neuroepidemiology)
Source: Neuroepidemiology - October 14, 2022 Category: Epidemiology Source Type: research
Associations among body mass index, waist-to-hip ratio and cognitive impairment tend to follow an opposite trend and are sex specific: A population-based cross-sectional study in a rural area of Xi'an, China
Conclusion:
The relationships among BMI, WHR and CI exhibit an opposite trend. A low BMI or high WHR was pos itively associated with CI, which was more prominent in males for a low BMI, and in females for a high WHR. (Source: Neuroepidemiology)
Source: Neuroepidemiology - October 13, 2022 Category: Epidemiology Source Type: research
Epidemiology of first and recurrent ischemic stroke in Sweden 2010 –2019 – A Riksstroke study
Conclusion: Whereas both first-ever and recurrent IS rates declined in Sweden between 2010 and 2019, the proportional decline was almost double for recurrent IS than for first-ever IS and most pronounced in the elderly. Increased use of secondary preventive drugs, in particular anticoagulants in atrial fibrillation, appears to have contributed, but further studies on precise causes for the decline in recurrent IS are needed. (Source: Neuroepidemiology)
Source: Neuroepidemiology - October 12, 2022 Category: Epidemiology Source Type: research
The Prevalence of Active Epilepsy in the Kingdom of Saudi Arabia : A cross sectional study
Conclusion: The prevalence of active epilepsy in KSA has dramatically decreased during the last decades to a rate lower than those reported in most developing countries.
Keywords: Epilepsy, door to door, epidemiology, prevalence, Saudi Arabia (Source: Neuroepidemiology)
Source: Neuroepidemiology - October 7, 2022 Category: Epidemiology Source Type: research
Breastfeeding and risk of multiple sclerosis: a systematic review and meta-analysis of observational studies
Conclusion: The meta-analysis showed a small protective effect of having been breastfed on MS risk. This adds to the knowledge that breastfeeding is beneficial for the immunological health of a child. Future studies on the influence of having been breastfed on MS risk should apply a uniform definition of breastfeeding and investigate possible sex-specific aspects. (Source: Neuroepidemiology)
Source: Neuroepidemiology - September 12, 2022 Category: Epidemiology Source Type: research
Lack of Familial Aggregation of the “Essential Tremor-Plus” Phenotype in Familial Essential Tremor
Conclusion: The data demonstrate that ET-plus does not seem to aggregate in families. As such, they do not lend support to the notion that ET-plus is a valid biological construct.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - August 8, 2022 Category: Epidemiology Source Type: research
Lack of Familial Aggregation of the “Essential-Tremor-Plus” Phenotype in Familial Essential Tremor
Conclusion: The data demonstrate that ET-plus does not seem to aggregate in families. As such, they do not lend support to the notion that ET-plus is a valid biological construct. (Source: Neuroepidemiology)
Source: Neuroepidemiology - August 8, 2022 Category: Epidemiology Source Type: research
Real-world effectiveness of lipid-lowering medications on outcomes after stroke: potential implications of the new-user design
Introduction: Observational studies are increasingly being used to provide evidence on the real-world effectiveness of medications for preventing vascular diseases, such as stroke. We investigated whether the real-world effectiveness of treatment with lipid-lowering medications after ischemic stroke is affected by prevalent user bias.
Methods: An observational cohort study of 90-day survivors of ischemic stroke, using person-level data from the Australian Stroke Clinical Registry (2012-2016; 45 hospitals) linked to administrative (pharmaceutical, hospital, death) records. Use of, and adherence to (proportion of days cove...
Source: Neuroepidemiology - July 21, 2022 Category: Epidemiology Source Type: research
