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Liquid biopsy guides anti-EGFR rechallenge in metastatic CRC
Nature Reviews Gastroenterology & Hepatology, Published online: 15 August 2022; doi:10.1038/s41575-022-00678-8Liquid biopsy guides anti-EGFR rechallenge in metastatic CRC (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - August 15, 2022 Category: Gastroenterology Authors: Eleni Kotsiliti Source Type: research

CIDEB variants protect against liver disease
Nature Reviews Gastroenterology & Hepatology, Published online: 15 August 2022; doi:10.1038/s41575-022-00680-0CIDEB variants protect against liver disease (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - August 15, 2022 Category: Gastroenterology Authors: Eleni Kotsiliti Source Type: research

Genetics of irritable bowel syndrome: shifting gear via biobank-scale studies
Nature Reviews Gastroenterology & Hepatology, Published online: 10 August 2022; doi:10.1038/s41575-022-00662-2Genetic predisposition contributes to disease pathophysiology in irritable bowel syndrome (IBS). This Review provides a comprehensive overview of genetic research in IBS and discusses new concepts in IBS genetics. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - August 10, 2022 Category: Gastroenterology Authors: Michael Camilleri Alexandra Zhernakova Isotta Bozzarelli Mauro D ’Amato Source Type: research

Gut immune cell trafficking: inter-organ communication and immune-mediated inflammation
Nature Reviews Gastroenterology & Hepatology, Published online: 09 August 2022; doi:10.1038/s41575-022-00663-1Intestinal immune cell trafficking contributes to the pathogenesis of immune-mediated inflammatory diseases (IMIDs). This Review discusses the underlying immune cell trafficking mechanisms along the gut–liver, gut–joint and gut–brain axes and provides an overview of their implications for treatment options in IMIDs. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - August 9, 2022 Category: Gastroenterology Authors: Sebastian Zundler Claudia G ünther Andreas E. Kremer Mario M. Zaiss Veit Rothhammer Markus F. Neurath Source Type: research

Stigma: a major barrier to hepatitis B elimination
Nature Reviews Gastroenterology & Hepatology, Published online: 03 August 2022; doi:10.1038/s41575-022-00670-2Advances in hepatitis B management are still not reaching most of the affected community. A major barrier to this translation is stigma. Research and clinical communities have a responsibility to mitigate stigma and ensure that the voices of the affected community are considered in decision-making conversations. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - August 3, 2022 Category: Gastroenterology Authors: Thomas Tu Source Type: research

ZBTB46+ ILC3s promote intestinal health
Nature Reviews Gastroenterology & Hepatology, Published online: 01 August 2022; doi:10.1038/s41575-022-00672-0ZBTB46+ ILC3s promote intestinal health (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - August 1, 2022 Category: Gastroenterology Authors: Jordan Hindson Source Type: research

The metabolic nature of inflammatory bowel diseases
Nature Reviews Gastroenterology & Hepatology, Published online: 29 July 2022; doi:10.1038/s41575-022-00658-yExperimental and clinical evidence supports a role of metabolic perturbation in the development of gut inflammation in inflammatory bowel disease (IBD). This Review discusses the role of diet and metabolic inflammation in IBD, outlining key concepts and highlighting the links between metabolism and inflammation in IBD. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - July 29, 2022 Category: Gastroenterology Authors: Timon E. Adolph Moritz Meyer Julian Schw ärzler Lisa Mayr Felix Grabherr Herbert Tilg Source Type: research

Hybrid ILC 2022
Nature Reviews Gastroenterology & Hepatology, Published online: 28 July 2022; doi:10.1038/s41575-022-00671-1Hybrid ILC 2022 (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - July 28, 2022 Category: Gastroenterology Authors: Eleni Kotsiliti Source Type: research

Hepatitis D virus: more attention needed
Nature Reviews Gastroenterology & Hepatology, Published online: 26 July 2022; doi:10.1038/s41575-022-00664-0Hepatitis D virus: more attention needed (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - July 26, 2022 Category: Gastroenterology Authors: Maria Buti Source Type: research

Fazirsiran shows promise for liver disease in AAT
Nature Reviews Gastroenterology & Hepatology, Published online: 25 July 2022; doi:10.1038/s41575-022-00668-wFazirsiran shows promise for liver disease in AAT (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - July 25, 2022 Category: Gastroenterology Authors: Katrina Ray Source Type: research

Saliva — a new route for enteric viruses
Nature Reviews Gastroenterology & Hepatology, Published online: 25 July 2022; doi:10.1038/s41575-022-00665-zSaliva — a new route for enteric viruses (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - July 25, 2022 Category: Gastroenterology Authors: Katrina Ray Source Type: research

Positive phase III results for odevixibat for progressive familial intrahepatic cholestasis
Nature Reviews Gastroenterology & Hepatology, Published online: 25 July 2022; doi:10.1038/s41575-022-00667-xPositive phase III results for odevixibat for progressive familial intrahepatic cholestasis (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - July 25, 2022 Category: Gastroenterology Authors: Katrina Ray Source Type: research

No increased risk of acute liver injury after COVID-19 vaccination
Nature Reviews Gastroenterology & Hepatology, Published online: 25 July 2022; doi:10.1038/s41575-022-00666-yNo increased risk of acute liver injury after COVID-19 vaccination (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - July 25, 2022 Category: Gastroenterology Authors: Katrina Ray Source Type: research

A roadmap for serum biomarkers for hepatitis B virus: current status and future outlook
Nature Reviews Gastroenterology & Hepatology, Published online: 20 July 2022; doi:10.1038/s41575-022-00649-zCurrently, there is no cure for hepatitis B virus (HBV) infection, which can lead to chronic liver disease and liver cancer, and only a few biomarkers are available. This Roadmap provides an overview of HBV serum biomarkers and their challenges. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - July 20, 2022 Category: Gastroenterology Authors: Anna Kramvis Kyong-Mi Chang Maura Dandri Patrizia Farci Dieter Glebe Jianming Hu Harry L. A. Janssen Daryl T. Y. Lau Capucine Penicaud Teresa Pollicino Barbara Testoni Florian Van B ömmel Ourania Andrisani Maria Beumont-Mauviel Timothy M. Block Henry L. Source Type: research

Benign liver tumours: understanding molecular physiology to adapt clinical management
Nature Reviews Gastroenterology & Hepatology, Published online: 14 July 2022; doi:10.1038/s41575-022-00643-5Here, the authors provide an overview of benign liver tumours (hepatic haemangioma, focal nodular hyperplasia and hepatocellular adenoma), including pathogenesis, diagnosis and management. Insights into how molecular physiology could inform clinical practice are also highlighted. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - July 14, 2022 Category: Gastroenterology Authors: Jean-Charles Nault Val érie Paradis Maxime Ronot Jessica Zucman-Rossi Source Type: research