See the reality again in the field of liver transplantation
Nature Reviews Gastroenterology & Hepatology, Published online: 27 November 2023; doi:10.1038/s41575-023-00876-yIn 2023, we witnessed advances in allocation policies and marginal donors, including living donors. Key improvements included the uncapped Model for End-stage Liver Disease 3.0 score, unveiled machine perfusion trials to standard deceased donors and lessons from the aborted living donor liver transplantations. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - November 27, 2023 Category: Gastroenterology Authors: Nam-Joon Yi Source Type: research

Amitriptyline as second-line treatment for IBS in primary care settings
Nature Reviews Gastroenterology & Hepatology, Published online: 21 November 2023; doi:10.1038/s41575-023-00873-1Amitriptyline as second-line treatment for IBS in primary care settings (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - November 21, 2023 Category: Gastroenterology Authors: Katrina Ray Source Type: research

Risk of HCC in individuals of sub-Saharan ethnicity or descent with chronic hepatitis B in Europe
Nature Reviews Gastroenterology & Hepatology, Published online: 21 November 2023; doi:10.1038/s41575-023-00875-zRisk of HCC in individuals of sub-Saharan ethnicity or descent with chronic hepatitis B in Europe (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - November 21, 2023 Category: Gastroenterology Authors: Katrina Ray Source Type: research

Resmetirom safe for nonalcoholic fatty liver disease
Nature Reviews Gastroenterology & Hepatology, Published online: 21 November 2023; doi:10.1038/s41575-023-00874-0Resmetirom safe for nonalcoholic fatty liver disease (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - November 21, 2023 Category: Gastroenterology Authors: Katrina Ray Source Type: research

Fresh perspectives on how to build, maintain and repair the ENS
Nature Reviews Gastroenterology & Hepatology, Published online: 17 November 2023; doi:10.1038/s41575-023-00870-4Enteric nervous system function is essential for survival. Studies published in 2023 have provided important novel insights into the mechanisms that regulate its development and maintenance, and demonstrate how it can be restored when these mechanisms fail. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - November 17, 2023 Category: Gastroenterology Authors: Werend Boesmans Source Type: research

Deciphering the different phases of preclinical inflammatory bowel disease
Nature Reviews Gastroenterology & Hepatology, Published online: 10 November 2023; doi:10.1038/s41575-023-00854-4Inflammatory bowel disease (IBD) is an immune-mediated inflammatory disease (IMID). Here, the authors review evidence on the preclinical phase of IBD, outlining and describing the proposed at-risk, initiation and expansion phases. Overlap with other IMIDs is discussed alongside the possible future directions for research into preclinical IBD. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - November 10, 2023 Category: Gastroenterology Authors: Jonas J. Rudbaek Manasi Agrawal Joana Torres Saurabh Mehandru Jean-Frederic Colombel Tine Jess Source Type: research

Implications of the evolving knowledge of the genetic architecture of MASLD
Nature Reviews Gastroenterology & Hepatology, Published online: 03 November 2023; doi:10.1038/s41575-023-00866-0Metabolic dysfunction-associated steatotic liver disease (MASLD) has a strong heritable component, and genome-wide association cohort studies are highlighting the major genetic determinants of this condition. A meta-analysis of these databases has now enabled expansion of the list of the inherited variants that modulate the risk of MASLD. The identification of new MASLD risk loci is improving comprehension of disease pathogenesis and individual risk stratification, and also enabling the identification of nove...
Source: Nature Reviews Gastroenterology and Hepatology - November 3, 2023 Category: Gastroenterology Authors: Luca V. C. Valenti Vittoria Moretti Source Type: research

Innovation is needed to increase viral hepatitis testing globally
Nature Reviews Gastroenterology & Hepatology, Published online: 02 November 2023; doi:10.1038/s41575-023-00865-1Innovative approaches to increase testing are needed to achieve the 2030 hepatitis B and hepatitis C elimination targets. Zhang et al., partnering with local community organizations, successfully used a pay-it-forward approach to increase hepatitis B and hepatitis C testing among men who have sex with men in China. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - November 2, 2023 Category: Gastroenterology Authors: Margaret E. Hellard Alisa Pedrana Source Type: research

Folate receptor-γ in MASH-related fibrosis
Nature Reviews Gastroenterology & Hepatology, Published online: 02 November 2023; doi:10.1038/s41575-023-00868-yFolate receptor-γ in MASH-related fibrosis (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - November 2, 2023 Category: Gastroenterology Authors: Eleni Kotsiliti Source Type: research

EASL SLD Summit 2023
Nature Reviews Gastroenterology & Hepatology, Published online: 25 October 2023; doi:10.1038/s41575-023-00863-3EASL SLD Summit 2023 (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - October 25, 2023 Category: Gastroenterology Authors: Jordan Hindson Source Type: research

A distinct CD103+Vγ4+ γδ T cell subset is linked to lesion healing and improved prognosis
Nature Reviews Gastroenterology & Hepatology, Published online: 25 October 2023; doi:10.1038/s41575-023-00862-4A distinct CD103+Vγ4+ γδ T cell subset is linked to lesion healing and improved prognosis (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - October 25, 2023 Category: Gastroenterology Authors: Caroline Barranco Source Type: research

Spotlight on infection control
Nature Reviews Gastroenterology & Hepatology, Published online: 20 October 2023; doi:10.1038/s41575-023-00861-5Spotlight on infection control (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - October 20, 2023 Category: Gastroenterology Authors: Caroline Barranco Source Type: research

Calls for human challenge vaccine trials
Nature Reviews Gastroenterology & Hepatology, Published online: 20 October 2023; doi:10.1038/s41575-023-00859-zCalls for human challenge vaccine trials (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - October 20, 2023 Category: Gastroenterology Authors: Caroline Barranco Source Type: research

SMART cancer risk prediction
Nature Reviews Gastroenterology & Hepatology, Published online: 20 October 2023; doi:10.1038/s41575-023-00860-6SMART cancer risk prediction (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - October 20, 2023 Category: Gastroenterology Authors: Caroline Barranco Source Type: research

No excess cancer risk for non-erosive disease
Nature Reviews Gastroenterology & Hepatology, Published online: 20 October 2023; doi:10.1038/s41575-023-00858-0No excess cancer risk for non-erosive disease (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - October 20, 2023 Category: Gastroenterology Authors: Caroline Barranco Source Type: research