Muscular fitness profiles in relation to the response in body fat during school-based high-intensity intervention
CONCLUSIONS: The findings may help teachers assess the potential and indirect changes in muscle performance after employing a body weight intervention (based on the HIIT program). A more targeted approach to treating adolescents with excessive BF, in parallel with improving MF, can be individually tailored.PMID:38358366 | DOI:10.23736/S0022-4707.24.15586-7 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - February 15, 2024 Category: Information Technology Authors: Jaros ław Domaradzki Dawid Ko źlenia Source Type: research
Muscular fitness profiles in relation to the response in body fat during school-based high-intensity intervention
CONCLUSIONS: The findings may help teachers assess the potential and indirect changes in muscle performance after employing a body weight intervention (based on the HIIT program). A more targeted approach to treating adolescents with excessive BF, in parallel with improving MF, can be individually tailored.PMID:38358366 | DOI:10.23736/S0022-4707.24.15586-7 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - February 15, 2024 Category: Information Technology Authors: Jaros ław Domaradzki Dawid Ko źlenia Source Type: research
Muscular fitness profiles in relation to the response in body fat during school-based high-intensity intervention
CONCLUSIONS: The findings may help teachers assess the potential and indirect changes in muscle performance after employing a body weight intervention (based on the HIIT program). A more targeted approach to treating adolescents with excessive BF, in parallel with improving MF, can be individually tailored.PMID:38358366 | DOI:10.23736/S0022-4707.24.15586-7 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - February 15, 2024 Category: Information Technology Authors: Jaros ław Domaradzki Dawid Ko źlenia Source Type: research
Muscular fitness profiles in relation to the response in body fat during school-based high-intensity intervention
CONCLUSIONS: The findings may help teachers assess the potential and indirect changes in muscle performance after employing a body weight intervention (based on the HIIT program). A more targeted approach to treating adolescents with excessive BF, in parallel with improving MF, can be individually tailored.PMID:38358366 | DOI:10.23736/S0022-4707.24.15586-7 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - February 15, 2024 Category: Information Technology Authors: Jaros ław Domaradzki Dawid Ko źlenia Source Type: research
Intramedullary Nail vs. Plate Fixation for Pathological Humeral Shaft Fracture: An Updated Narrative Review and Meta-Analysis of Surgery-Related Factors
Conclusions: Considering the short life expectancy of end-stage patients, the choice of surgical method depends on the patient's individual condition, fracture and lesion patterns, the surgeon's experience, and comprehensive discussion between the surgeon and patient.PMID:38337449 | PMC:PMC10856436 | DOI:10.3390/jcm13030755 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - February 10, 2024 Category: Information Technology Authors: Bing-Kuan Chen Ting-Han Tai Shu-Hsuan Lin Kuan-Hao Chen Yu-Min Huang Chih-Yu Chen Source Type: research
Impact of COVID-19 infection on baseline autonomic symptoms in patients with preexisting Postural Tachycardia Syndrome and Orthostatic Intolerance: A retrospective study
CONCLUSIONS: Patients with pre-existing POTS, most experienced a worsening of their baseline autonomic symptoms after suffering the COVID-19 infection which required additional pharmacotherapy for their symptom improvement.PMID:38340983 | DOI:10.1016/j.amjms.2023.12.011 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - February 10, 2024 Category: Information Technology Authors: Chandramohan Meenakshisundaram Abdelmoniem Moustafa Meghana Ranabothu Ahmed Maraey Blair Grubb Source Type: research
Exploring clinical indicator variations in stroke patients with multiple risk factors: focus on hypertension and inflammatory reactions
CONCLUSION: Age is correlated with an elevated risk of stroke. Individuals exhibiting multiple stroke risk factors and diverse ischemic stroke subtypes commonly present with abnormal lipid levels and imbalances in Th1/Th2 cytokines. These factors significantly contribute to the onset and progression of stroke. Furthermore, inflammatory responses, particularly those induced by atherosclerosis, play a pivotal role in the genesis of stroke and exert a substantial influence on its prognosis.PMID:38287458 | PMC:PMC10823715 | DOI:10.1186/s40001-024-01653-6 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - January 30, 2024 Category: Information Technology Authors: Jiejie Guo Mei Tian Yongang Li Yitong Guo Ting Zhang Xuan Liu Jinze Shen Lin Zhang Yueqi Yu Ling Cao Haiyan Gu Yanfang Li Shiwei Duan Qinwen Wang Source Type: research
PerSurge (NOA-30) phase II trial of perampanel treatment around surgery in patients with progressive glioblastoma
DISCUSSION: This trial is set up to assess first indications of clinical efficacy and tolerability of perampanel in recurrent glioblastoma, a repurposed drug which inhibits neuron-glioma synapses and thereby glioblastoma growth in preclinical models. If perampanel proved to be successful in the clinical setting, it would provide the first evidence that interference with neuron-cancer interactions may indeed lead to a benefit for patients, which would lay the foundation for a larger confirmatory trial in the future.TRIAL REGISTRATION: EU-CT number: 2023-503938-52-00 30.11.2023.PMID:38279087 | PMC:PMC10811925 | DOI:10.1186/s...
Source: Methods of Information in Medicine - January 26, 2024 Category: Information Technology Authors: Sophie Heuer Ina Burghaus Maria Gose Tobias Kessler Felix Sahm Philipp Vollmuth Varun Venkataramani Dirk Hoffmann Matthias Schlesner Miriam Ratliff Carsten Hopf Ulrich Herrlinger Franz Ricklefs Martin Bendszus Sandro M Krieg Antje Wick Wolfgang Wick Frank Source Type: research
Association between pathological infiltrative tumor growth pattern and prognosis in patients with resected lung squamous cell carcinoma
CONCLUSION: Our study highlights a novel pathological concept of INF in LUSC, and contributed to the proposal that it is a factor indicating an unfavorable prognosis in patients with early-stage LUSC. A prospective multicenter study is warranted for INFc patients, as careful follow-up and adjuvant chemotherapy might lead to the early detection and prevention of recurrence.PMID:38262301 | DOI:10.1016/j.ejso.2024.107973 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - January 23, 2024 Category: Information Technology Authors: Chiaki Kanno Yujin Kudo Jun Matsubayashi Hideyuki Furumoto Satoshi Takahashi Sachio Maehara Masaru Hagiwara Masatoshi Kakihana Tatsuo Ohira Toshitaka Nagao Norihiko Ikeda Source Type: research
Artificial Intelligence-Based Prediction of Contrast Medium Doses for Computed Tomography Angiography Using Optimized Clinical Parameter Sets
CONCLUSION: We developed a reliable hybrid system that helps radiologists determine the optimal contrast dose for CT angiography based on patient-specific parameters.PMID:38262476 | DOI:10.1055/s-0044-1778694 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - January 23, 2024 Category: Information Technology Authors: Marja Fleitmann Hristina Uzunova Ren é Pallenberg Andreas M Stroth Jan Gerlach Alexander F ürschke J örg Barkhausen Arpad Bischof Heinz Handels Source Type: research
Cardiorespiratory fitness is linked with heart rate variability during stress in "at-risk" adults
CONCLUSIONS: CRF is positively associated with prevailing vagally mediated HRV at everyday levels of physical and psychosocial stress in adults with cardiovascular risk factors.PMID:38213267 | DOI:10.23736/S0022-4707.23.15373-4 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - January 12, 2024 Category: Information Technology Authors: Anniina Salmio Antti-Pekka E Rissanen Jari L O Kurkela Mirva Rottensteiner Santtu Seip äjärvi Joona Juurakko Urho M Kujala Jari A Laukkanen Jan Wikgren Source Type: research
Influence of menstrual cycle phase and oral contraceptive phase on exercise performance in endurance-trained females
CONCLUSIONS: Collectively, our study suggests that MC phase and OCP influence exercise performance to a limited extent in endurance-trained females.PMID:38213268 | DOI:10.23736/S0022-4707.23.15458-2 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - January 12, 2024 Category: Information Technology Authors: Mikkel Oxfeldt Louise K Frederiksen Thomas Gunnarson Mette Hansen Source Type: research
Geometric Deep Learning for Unsupervised Registration of Diffusion Magnetic Resonance Images
Inf Process Med Imaging. 2023 Jun;13939:563-575. doi: 10.1007/978-3-031-34048-2_43. Epub 2023 Jun 8.ABSTRACTDeep learning based models for registration predict a transformation directly from moving and fixed image appearances. These models have revolutionized the field of medical image registration, achieving accuracy on-par with classical registration methods at a fraction of the computation time. Unfortunately, most deep learning based registration methods have focused on scalar imaging modalities such as T1/T2 MRI and CT, with less attention given to more complex modalities such as diffusion MRI. In this paper, to the b...
Source: Methods of Information in Medicine - January 11, 2024 Category: Information Technology Authors: Jose J Bouza Chun-Hao Yang Baba C Vemuri Source Type: research
Efficacy and safety of biologics in primary sclerosing cholangitis with inflammatory bowel disease: A systematic review and meta-analysis
CONCLUSIONS: Treatment of patients with PSC-IBD with biologics (vedolizumab, infliximab, and adalimumab) was not associated with improvement of biochemical markers of cholestasis. Biologics are effective in treating the colitis associated with PSC. Vedolizumab was associated with worsening liver enzymes in contrast to other biologics, a finding that warrants further study.PMID:38206197 | PMC:PMC10786591 | DOI:10.1097/HC9.0000000000000347 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - January 11, 2024 Category: Information Technology Authors: Ayesha Shah Michael P Jones Gavin Callaghan Thomas Fairlie Xiaomin Ma Emma L Culver Katherine Stuart Peter De Cruz James O'Beirne James H Tabibian Axel Dignass Ali Canbay Gregory J Gores Gerald J Holtmann Source Type: research
Acellular scaffold-based approach for in situ genetic engineering of host T-cells in solid tumor immunotherapy
CONCLUSION: Our scaffold-based T-cell therapy presents an innovative in situ localized approach for programming T-cells to target solid tumors. This approach offers a viable alternative to in vitro manipulation of T-cells, circumventing the need for large-scale in vitro generation and culture of tumor-specific T-cells. It offers an off-the-shelf alternative that facilitates the use of host cells instead of allogeneic cells, thereby, overcoming a major hurdle.PMID:38173045 | PMC:PMC10765574 | DOI:10.1186/s40779-023-00503-6 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - January 4, 2024 Category: Information Technology Authors: Hiren Y Dandia Mamatha M Pillai Deepak Sharma Meghna Suvarna Neha Dalal Ayush Madhok Arvind Ingle Shubhada V Chiplunkar Sanjeev Galande Prakriti Tayalia Source Type: research
