Cardiorespiratory fitness is linked with heart rate variability during stress in "at-risk" adults
CONCLUSIONS: CRF is positively associated with prevailing vagally mediated HRV at everyday levels of physical and psychosocial stress in adults with cardiovascular risk factors.PMID:38213267 | DOI:10.23736/S0022-4707.23.15373-4 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - January 12, 2024 Category: Information Technology Authors: Anniina Salmio Antti-Pekka E Rissanen Jari L O Kurkela Mirva Rottensteiner Santtu Seip äjärvi Joona Juurakko Urho M Kujala Jari A Laukkanen Jan Wikgren Source Type: research

Influence of menstrual cycle phase and oral contraceptive phase on exercise performance in endurance-trained females
CONCLUSIONS: Collectively, our study suggests that MC phase and OCP influence exercise performance to a limited extent in endurance-trained females.PMID:38213268 | DOI:10.23736/S0022-4707.23.15458-2 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - January 12, 2024 Category: Information Technology Authors: Mikkel Oxfeldt Louise K Frederiksen Thomas Gunnarson Mette Hansen Source Type: research

Geometric Deep Learning for Unsupervised Registration of Diffusion Magnetic Resonance Images
Inf Process Med Imaging. 2023 Jun;13939:563-575. doi: 10.1007/978-3-031-34048-2_43. Epub 2023 Jun 8.ABSTRACTDeep learning based models for registration predict a transformation directly from moving and fixed image appearances. These models have revolutionized the field of medical image registration, achieving accuracy on-par with classical registration methods at a fraction of the computation time. Unfortunately, most deep learning based registration methods have focused on scalar imaging modalities such as T1/T2 MRI and CT, with less attention given to more complex modalities such as diffusion MRI. In this paper, to the b...
Source: Methods of Information in Medicine - January 11, 2024 Category: Information Technology Authors: Jose J Bouza Chun-Hao Yang Baba C Vemuri Source Type: research

Efficacy and safety of biologics in primary sclerosing cholangitis with inflammatory bowel disease: A systematic review and meta-analysis
CONCLUSIONS: Treatment of patients with PSC-IBD with biologics (vedolizumab, infliximab, and adalimumab) was not associated with improvement of biochemical markers of cholestasis. Biologics are effective in treating the colitis associated with PSC. Vedolizumab was associated with worsening liver enzymes in contrast to other biologics, a finding that warrants further study.PMID:38206197 | PMC:PMC10786591 | DOI:10.1097/HC9.0000000000000347 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - January 11, 2024 Category: Information Technology Authors: Ayesha Shah Michael P Jones Gavin Callaghan Thomas Fairlie Xiaomin Ma Emma L Culver Katherine Stuart Peter De Cruz James O'Beirne James H Tabibian Axel Dignass Ali Canbay Gregory J Gores Gerald J Holtmann Source Type: research

Acellular scaffold-based approach for in situ genetic engineering of host T-cells in solid tumor immunotherapy
CONCLUSION: Our scaffold-based T-cell therapy presents an innovative in situ localized approach for programming T-cells to target solid tumors. This approach offers a viable alternative to in vitro manipulation of T-cells, circumventing the need for large-scale in vitro generation and culture of tumor-specific T-cells. It offers an off-the-shelf alternative that facilitates the use of host cells instead of allogeneic cells, thereby, overcoming a major hurdle.PMID:38173045 | PMC:PMC10765574 | DOI:10.1186/s40779-023-00503-6 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - January 4, 2024 Category: Information Technology Authors: Hiren Y Dandia Mamatha M Pillai Deepak Sharma Meghna Suvarna Neha Dalal Ayush Madhok Arvind Ingle Shubhada V Chiplunkar Sanjeev Galande Prakriti Tayalia Source Type: research

Acellular scaffold-based approach for in situ genetic engineering of host T-cells in solid tumor immunotherapy
CONCLUSION: Our scaffold-based T-cell therapy presents an innovative in situ localized approach for programming T-cells to target solid tumors. This approach offers a viable alternative to in vitro manipulation of T-cells, circumventing the need for large-scale in vitro generation and culture of tumor-specific T-cells. It offers an off-the-shelf alternative that facilitates the use of host cells instead of allogeneic cells, thereby, overcoming a major hurdle.PMID:38173045 | PMC:PMC10765574 | DOI:10.1186/s40779-023-00503-6 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - January 4, 2024 Category: Information Technology Authors: Hiren Y Dandia Mamatha M Pillai Deepak Sharma Meghna Suvarna Neha Dalal Ayush Madhok Arvind Ingle Shubhada V Chiplunkar Sanjeev Galande Prakriti Tayalia Source Type: research

Acellular scaffold-based approach for in situ genetic engineering of host T-cells in solid tumor immunotherapy
CONCLUSION: Our scaffold-based T-cell therapy presents an innovative in situ localized approach for programming T-cells to target solid tumors. This approach offers a viable alternative to in vitro manipulation of T-cells, circumventing the need for large-scale in vitro generation and culture of tumor-specific T-cells. It offers an off-the-shelf alternative that facilitates the use of host cells instead of allogeneic cells, thereby, overcoming a major hurdle.PMID:38173045 | PMC:PMC10765574 | DOI:10.1186/s40779-023-00503-6 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - January 4, 2024 Category: Information Technology Authors: Hiren Y Dandia Mamatha M Pillai Deepak Sharma Meghna Suvarna Neha Dalal Ayush Madhok Arvind Ingle Shubhada V Chiplunkar Sanjeev Galande Prakriti Tayalia Source Type: research

Acellular scaffold-based approach for in situ genetic engineering of host T-cells in solid tumor immunotherapy
CONCLUSION: Our scaffold-based T-cell therapy presents an innovative in situ localized approach for programming T-cells to target solid tumors. This approach offers a viable alternative to in vitro manipulation of T-cells, circumventing the need for large-scale in vitro generation and culture of tumor-specific T-cells. It offers an off-the-shelf alternative that facilitates the use of host cells instead of allogeneic cells, thereby, overcoming a major hurdle.PMID:38173045 | PMC:PMC10765574 | DOI:10.1186/s40779-023-00503-6 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - January 4, 2024 Category: Information Technology Authors: Hiren Y Dandia Mamatha M Pillai Deepak Sharma Meghna Suvarna Neha Dalal Ayush Madhok Arvind Ingle Shubhada V Chiplunkar Sanjeev Galande Prakriti Tayalia Source Type: research

Acellular scaffold-based approach for in situ genetic engineering of host T-cells in solid tumor immunotherapy
CONCLUSION: Our scaffold-based T-cell therapy presents an innovative in situ localized approach for programming T-cells to target solid tumors. This approach offers a viable alternative to in vitro manipulation of T-cells, circumventing the need for large-scale in vitro generation and culture of tumor-specific T-cells. It offers an off-the-shelf alternative that facilitates the use of host cells instead of allogeneic cells, thereby, overcoming a major hurdle.PMID:38173045 | DOI:10.1186/s40779-023-00503-6 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - January 4, 2024 Category: Information Technology Authors: Hiren Y Dandia Mamatha M Pillai Deepak Sharma Meghna Suvarna Neha Dalal Ayush Madhok Arvind Ingle Shubhada V Chiplunkar Sanjeev Galande Prakriti Tayalia Source Type: research

Current Trends and New Approaches in Participatory Health Informatics
Methods Inf Med. 2023 Dec 29. doi: 10.1055/s-0043-1777732. Online ahead of print.NO ABSTRACTPMID:38158213 | DOI:10.1055/s-0043-1777732 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - December 29, 2023 Category: Information Technology Authors: Kerstin Denecke Elia Gabarron Carolyn Petersen Source Type: research

Current Trends and New Approaches in Participatory Health Informatics
Methods Inf Med. 2023 Dec 29. doi: 10.1055/s-0043-1777732. Online ahead of print.NO ABSTRACTPMID:38158213 | DOI:10.1055/s-0043-1777732 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - December 29, 2023 Category: Information Technology Authors: Kerstin Denecke Elia Gabarron Carolyn Petersen Source Type: research

A cross-sectional study to compare levels of physical activity among adolescents in rural and urban areas of Western Maharashtra
CONCLUSION: Higher proportion of adolescents performing adequate physical activity is likely to be a key factor in keeping the BMI and TMI lower in rural as compared to urban adolescent population.PMID:38144661 | PMC:PMC10746802 | DOI:10.1016/j.mjafi.2022.10.003 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - December 25, 2023 Category: Information Technology Authors: Avadhesh Singh Malik Kunal Chatterjee Source Type: research

A cross-sectional study to compare levels of physical activity among adolescents in rural and urban areas of Western Maharashtra
CONCLUSION: Higher proportion of adolescents performing adequate physical activity is likely to be a key factor in keeping the BMI and TMI lower in rural as compared to urban adolescent population.PMID:38144661 | PMC:PMC10746802 | DOI:10.1016/j.mjafi.2022.10.003 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - December 25, 2023 Category: Information Technology Authors: Avadhesh Singh Malik Kunal Chatterjee Source Type: research

A cross-sectional study to compare levels of physical activity among adolescents in rural and urban areas of Western Maharashtra
CONCLUSION: Higher proportion of adolescents performing adequate physical activity is likely to be a key factor in keeping the BMI and TMI lower in rural as compared to urban adolescent population.PMID:38144661 | PMC:PMC10746802 | DOI:10.1016/j.mjafi.2022.10.003 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - December 25, 2023 Category: Information Technology Authors: Avadhesh Singh Malik Kunal Chatterjee Source Type: research

A cross-sectional study to compare levels of physical activity among adolescents in rural and urban areas of Western Maharashtra
CONCLUSION: Higher proportion of adolescents performing adequate physical activity is likely to be a key factor in keeping the BMI and TMI lower in rural as compared to urban adolescent population.PMID:38144661 | PMC:PMC10746802 | DOI:10.1016/j.mjafi.2022.10.003 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - December 25, 2023 Category: Information Technology Authors: Avadhesh Singh Malik Kunal Chatterjee Source Type: research