Addressing Inequities in Kidney Care for Indigenous People in Canada
(Source: Journal of the American Society of Nephrology : JASN)
Source: Journal of the American Society of Nephrology : JASN - July 29, 2022 Category: Urology & Nephrology Authors: Harasemiw, O., Komenda, P., Tangri, N. Tags: Addressing Racial and Ethnic Disparities in Kidney Disease Source Type: research

Housing: A Critical Contributor to Kidney Disease Disparities
(Source: Journal of the American Society of Nephrology : JASN)
Source: Journal of the American Society of Nephrology : JASN - July 29, 2022 Category: Urology & Nephrology Authors: Novick, T. K., Baweja, M., on behalf of the American Society of Nephrology Healthcare Justice Committee Advocacy and Scholarship Work Group, American Society of Nephrology Healthcare Justice Committee Advocacy and Scholarship Work Group are, Novick, Bawej Tags: Addressing Racial and Ethnic Disparities in Kidney Disease Source Type: research

Optimizing the Design and Analysis of Future AKI Trials
This article, derived from the "AKI" session of the "Kidney Disease Clinical Trialists" virtual workshop held in October 2021, reviews barriers to and strategies for improving the design and implementation of clinical trials in patients with, or at risk of, developing AKI. The novel approaches to trial design included in this review span adaptive trial designs that increase the knowledge gained from each trial participant; pragmatic trial designs that allow for the efficient enrollment of sufficiently large numbers of patients to detect small, but clinically significant, treatment effects; and platform trial designs that u...
Source: Journal of the American Society of Nephrology : JASN - July 29, 2022 Category: Urology & Nephrology Authors: Legrand, M., Bagshaw, S. M., Koyner, J. L., Schulman, I. H., Mathis, M. R., Bernholz, J., Coca, S., Gallagher, M., Gaudry, S., Liu, K. D., Mehta, R. L., Pirracchio, R., Ryan, A., Steubl, D., Stockbridge, N., Erlandsson, F., Turan, A., Wilson, F. P., Zarbo Tags: Special Article Source Type: research

High-Resolution Mass Spectrometry for the Measurement of PTH and PTH Fragments: Insights into PTH Physiology and Bioactivity
Full-length parathyroid hormone (PTH 1–84) is crucial for the regulation of calcium and phosphate homeostasis and bone remodeling. PTH 1–84 is metabolized into various PTH fragments, which are measured with varying levels of efficiency by PTH immunoassays. These PTH fragments, which increase in serum as CKD progresses, could potentially modulate the effects of PTH 1–84 and contribute to CKD-associated bone disorders. To obtain a true biologic representation of total PTH bioactivity, it is necessary to measure not only PTH 1–84 but also PTH fragments that are present in circulation. Traditional secon...
Source: Journal of the American Society of Nephrology : JASN - July 29, 2022 Category: Urology & Nephrology Authors: Ulmer, C. Z., Kritmetapak, K., Singh, R. J., Vesper, H. W., Kumar, R. Tags: Review Source Type: research

Vaccination, Transplantation, and a Social Contract
(Source: Journal of the American Society of Nephrology : JASN)
Source: Journal of the American Society of Nephrology : JASN - July 29, 2022 Category: Urology & Nephrology Authors: Kates, O. S., Limaye, A. P., Kaplan, B. Tags: Perspective Source Type: research

Collaboration between Dialysis Providers
(Source: Journal of the American Society of Nephrology : JASN)
Source: Journal of the American Society of Nephrology : JASN - July 29, 2022 Category: Urology & Nephrology Authors: Silberzweig, J., Bhat, J. G., Dittrich, M. O., Durvasula, R., Giullian, J., Hymes, J. L., Johnson, D., Schiller, B., Spech, R., Spry, L., Walker, G. S., Watnick, S., Yee, J., Freedman, B. I. Tags: Perspective Source Type: research

Unfulfilled Expectations Open New Horizons: What Have We Learned about Volume-Regulated Anion Channels in the Kidney?
(Source: Journal of the American Society of Nephrology : JASN)
Source: Journal of the American Society of Nephrology : JASN - July 29, 2022 Category: Urology & Nephrology Authors: Pochynyuk, O., Palygin, O. Tags: Editorial Source Type: research

Identifying Antigen-Specific T Cells in ANCA-Associated Vasculitis: A Glimpse of the Future?
(Source: Journal of the American Society of Nephrology : JASN)
Source: Journal of the American Society of Nephrology : JASN - July 29, 2022 Category: Urology & Nephrology Authors: Shochet, L., Kitching, A. R. Tags: Editorial Source Type: research

Polycystin-2 in the Endoplasmic Reticulum: Bending Ideas about the Role of the Cilium
(Source: Journal of the American Society of Nephrology : JASN)
Source: Journal of the American Society of Nephrology : JASN - July 29, 2022 Category: Urology & Nephrology Authors: Caplan, M. J. Tags: Editorial Source Type: research

This Months Highlights
(Source: Journal of the American Society of Nephrology : JASN)
Source: Journal of the American Society of Nephrology : JASN - July 29, 2022 Category: Urology & Nephrology Tags: This Month ' s Highlights Source Type: research

Authors Reply: Clinical Studies of Vaccine Efficacy
(Source: Journal of the American Society of Nephrology : JASN)
Source: Journal of the American Society of Nephrology : JASN - June 30, 2022 Category: Urology & Nephrology Authors: Bell, S., Campbell, J., Lambourg, E., Mark, P. Tags: Letter to the Editor Source Type: research

Authors Reply: Calcium-Based Phosphate Binders and Plasma Oxalate Concentration in Dialysis Patients
(Source: Journal of the American Society of Nephrology : JASN)
Source: Journal of the American Society of Nephrology : JASN - June 30, 2022 Category: Urology & Nephrology Authors: Pfau, A., Knauf, F. Tags: Letter to the Editor Source Type: research

Clinical Studies of Vaccine Efficacy
(Source: Journal of the American Society of Nephrology : JASN)
Source: Journal of the American Society of Nephrology : JASN - June 30, 2022 Category: Urology & Nephrology Authors: Ashby, D. Tags: Letter to the Editor Source Type: research

Calcium-Based Phosphate Binders and Plasma Oxalate Concentration in Dialysis Patients
(Source: Journal of the American Society of Nephrology : JASN)
Source: Journal of the American Society of Nephrology : JASN - June 30, 2022 Category: Urology & Nephrology Authors: Oka, Y., Miyazaki, M., Takatsu, S., Matsuda, H. Tags: Letter to the Editor Source Type: research

Kidney Biopsy Features Most Predictive of Clinical Outcomes in the Spectrum of Minimal Change Disease and Focal Segmental Glomerulosclerosis
Conclusions The most predictive descriptors of clinical outcomes among MCD/FSGS patients reflected structural changes in multiple renal compartments. Reporting these descriptors should be standardized to guide prognostication of proteinuric glomerular diseases. (Source: Journal of the American Society of Nephrology : JASN)
Source: Journal of the American Society of Nephrology : JASN - June 30, 2022 Category: Urology & Nephrology Authors: Zee, J., Liu, Q., Smith, A. R., Hodgin, J. B., Rosenberg, A., Gillespie, B. W., Holzman, L. B., Barisoni, L., Mariani, L. H., for the Nephrotic Syndrome Study Network (NEPTUNE), The NEPTUNE Members, Adler, Alter, Athavale, Atkinson, Avila-Casado, Bagnasco Tags: Glomerulonephritis and Interstitial Nephritis Source Type: research