Journal of Microbiology and Biotechnology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Genomic Characterization and Safety Assessment of Bifidobacterium breve BS2- PB3 as Functional Food
In conclusion, B. breve BS2-PB3 demonstrated a sufficient safety profile, making it a promising candidate for further development as a potential functional food.PMID:38494884 | DOI:10.4014/jmb.2311.11031 (Source: Journal of Microbiology and Biotechnology)
Source: Journal of Microbiology and Biotechnology - March 18, 2024 Category: Biotechnology Authors: Kristin Talia Marbun Marcelia Sugata Jonathan Suciono Purnomo None Dikson Samuel Owen Mudana Tan Tjie Jan Juandy Jo Source Type: research

Phloroglucinol Enhances Anagen Signaling and Alleviates H 2 O 2 -Induced Oxidative Stress in Human Dermal Papilla Cells
In this study, we investigated the therapeutic potential of PG for improving hair loss. A non-cytotoxic concentration of PG increased anagen-inductive genes and transcriptional activities of β-Catenin. Since several anagen-inductive genes are regulated by β-Catenin, further experiments were performed to elucidate the molecular mechanism by which PG upregulates anagen signaling. Various biochemical analyses revealed that PG upregulated β-Catenin signaling without affecting the expression of Wnt. In particular, PG elevated the phosphorylation of protein kinase B (AKT), leading to an increase in the inhibitory phosphorylat...
Source: Journal of Microbiology and Biotechnology - March 13, 2024 Category: Biotechnology Authors: Seokmuk Park Ye Jin Lim Hee Su Kim Hee-Jae Shin Ji-Seon Kim Jae Nam Lee Jae Ho Lee Seunghee Bae Source Type: research

Melanin Inhibitory Effect of Tuber himalayense Isolated in Incheon, Korea
In this study, we investigated the effect of Tuber himalayense extract on melanin synthesis in α-melanocyte-stimulating hormone (α-MSH)-treated B16F10 melanoma cells. We confirmed that T. himalayense extract was not toxic to α-MSH-treated B16F10 melanoma cells and exhibited a significant inhibitory effect on melanin synthesis at concentrations of 25, 50, and 100 μg/ml. Additionally, the T. himalayense extract inhibited melanin, TRP-1, TRP-2, tyrosinase, and MITF, which are enzymes involved in melanin synthesis, in a concentration-dependent manner. Furthermore, T. himalayense extract inhibited the mitogen-activated prot...
Source: Journal of Microbiology and Biotechnology - March 13, 2024 Category: Biotechnology Authors: Byeong Min Choi Minkyeong Kim Hyehyun Hong Tae-Jin Park Changmu Kim Jin-Soo Park Won-Jae Chi Seung-Young Kim Source Type: research

Ganodermanontriol Suppresses the Progression of Lung Adenocarcinoma by Activating CES2 to Enhance the Metabolism of Mycophenolate Mofetil
J Microbiol Biotechnol. 2024 Feb 28;34(2):249-261. doi: 10.4014/jmb.2306.06020. Epub 2023 Oct 1.ABSTRACTNew anti-lung cancer therapies are urgently required to improve clinical outcomes. Since ganodermanontriol (GDNT) has been identified as a potential antineoplastic agent, its role in lung adenocarcinoma (LUAD) is investigated in this study. Concretely, lung cancer cells were treated with GDNT and/or mycophenolate mofetil (MMF), after which MTT assay, flow cytometry and Western blot were conducted. Following bioinformatics analysis, carboxylesterase 2 (CES2) was knocked down and rescue assays were carried out in vitro. Xe...
Source: Journal of Microbiology and Biotechnology - February 29, 2024 Category: Biotechnology Authors: Qingfeng Xie Zhuo Cao Weiling You Xiaoping Cai Mei Shen Zhangyong Yin Yiwei Jiang Xin Wang Siyu Ye Source Type: research

Corrigendum to: Valeriana jatamansi Jones Inhibits Rotavirus-Induced Diarrhea via Phosphatidylinositol 3-Kinase/Protein Kinase B Signaling Pathway
J Microbiol Biotechnol. 2024 Feb 28;34(2):484-485. doi: 10.4014/jmb.2024.3402.484.NO ABSTRACTPMID:38419325 | DOI:10.4014/jmb.2024.3402.484 (Source: Journal of Microbiology and Biotechnology)
Source: Journal of Microbiology and Biotechnology - February 29, 2024 Category: Biotechnology Authors: Bin Zhang Yan Wang Chunmao Jiang Caihong Wu Guangfu Guo Xiaolan Chen Shulei Qiu Source Type: research