Journal of Lower Genital Tract Disease This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Evaluation of Folate Receptor-Mediated Cervical Dyeing as a Method for Detection of Cervical Lesions
Objectives The aim of the study was to evaluate the performance of a folate receptor–mediated tumor detection (FRD) assay for detection of cervical high-grade lesions. Materials and Method A total of 1504 patients with abnormal cytology and/or positive human papillomavirus (HPV) testing during primary screening from November 2014 to August 2015 were enrolled. The patients were recruited from the Peking University People's Hospital and 12 other hospitals. Folate receptor–mediated tumor detection was applied in all the patients before colposcopy to compare the detection rate, sensitivity, specificity, positive predi...
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: HPV-Associated Disease: Diagnosis and Management Source Type: research

Factors Related to Overtreatment in the See-and-Treat Approach: A Retrospective Multicentric Observational Study
Objective The aim of the study was to evaluate the association between colposcopic features, age, menopausal status, and overtreatment in women subjected to “see-and-treat” approach, to identify subgroups of patients in which this approach could be more appropriate. Materials and Methods Retrospective multicentric cohort study conducted on women older than 25 years, with a high-grade squamous cytological report and a visible squamocolumnar junction, in which colposcopy and the excisional procedure were performed at the same time without a previous cervical biopsy (see and treat). Overtreatment was defined as histo...
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: HPV-Associated Disease: Diagnosis and Management Source Type: research

Simple Hysterectomy for Cervical Cancer: Risk Factors for Failed Screening and Deviation From Screening Guidelines
Conclusions The most common cause of incidental cervical cancer at the time of simple hysterectomy was failure to properly adhere to screening guidelines. Less frequently, false-negative screening was the cause. No independent risk factor in either group was identified in this single institutional study. Illustrated is the importance of continuing education of surgeons about adequate screening in the preoperative evaluation for benign hysterectomy. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: HPV-Associated Disease: Diagnosis and Management Source Type: research

Reimbursement Incentives to Improve Adherence to Follow-Up of Cervical Cancer Cytology Screening Results in Peru
Objective The purpose of this study was to determine Peruvian women's attitudes toward novel reimbursement incentives used to improve adherence to obtaining cervical cytology test results. Materials and Methods Women presenting for cervical cancer screening in Peru completed a 34-item Investigational Review Board-approved questionnaire. The questionnaire determined their attitudes toward various reimbursement incentives to improve adherence to obtaining cervical cytology results. Descriptive statistics, generalized linear models, and Kruskal-Wallis tests were used in the analyses. Results Completed questionnaires w...
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: HPV-Associated Disease: Diagnosis and Management Source Type: research

Observed Colposcopy Practice in US Community-Based Clinics: The Retrospective Control Arm of the IMPROVE-COLPO Study
Objective The aim of the study was to characterize colposcopy practice and management of women with cervical abnormalities in US community-based clinics. Materials and Methods IMPROVE-COLPO was a 2-arm study of colposcopy patients with an abnormal screening result. The prospective arm recruited women to undergo examination with a commercial digital colposcope. The retrospective-control arm collected data (chart review) from previous colposcopies performed using standard equipment and methods. From the retrospective arm, we analyzed referral trends, colposcopy and biopsy practice, and management patterns. Results We...
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: HPV-Associated Disease: Diagnosis and Management Source Type: research

Cervical, Vaginal, and Vulvar Cancer Costs Incurred by the Medicaid Program in Publicly Insured Patients in Texas
Conclusions The direct medical costs associated with cervical, vaginal, and vulvar cancers in Texas Medicaid were substantial in the first 2 years after cancer diagnosis, but dual eligibility for Medicare coverage attenuated Medicaid costs. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: HPV-Associated Disease: Diagnosis and Management Source Type: research

Guidelines for Cervical Cancer Screening in Immunosuppressed Women Without HIV Infection
The objective of this report was to summarize current knowledge of CC, squamous intraepithelial lesions, and human papillomavirus (HPV) infection in non-HIV immunocompromised women to determine best practices for CC surveillance in this population and provide recommendations for screening. We evaluated those with solid organ transplant, hematopoietic stem cell transplant, and a number of autoimmune diseases. A panel of health care professionals involved in CC research and care was assembled to review and discuss existing literature on the subject and come to conclusions about screening based on available evidence and expe...
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: HPV-Associated Disease: Diagnosis and Management Source Type: research

Why Do Women Get Cervical Cancer in an Organized Screening Program in Canada?
Conclusions Although nonparticipation in screening is the greatest factor associated with cervical cancer diagnosis, failure of cervical cytology to detect cytologic abnormalities in women 2 to 3 and 3 to 5 years before diagnosis is of concern. Efforts must be directed to recruitment of women for screening as well as improving the sensitivity of screening tests to detect existing abnormalities. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - January 1, 2019 Category: OBGYN Tags: Original Research Articles: Cervix and HPV Source Type: research

Response to “Immediate Loop Electrode Excisional Procedure for High-Grade Cervical Cytology: One Size Fits All?”
No abstract available (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - December 25, 2018 Category: OBGYN Tags: Letters to the Editor Source Type: research

Immediate Loop Electrode Excisional Procedure for High-Grade Cervical Cytology: One Size Fits All?
No abstract available (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - December 25, 2018 Category: OBGYN Tags: Letters to the Editor Source Type: research

Vulvar Edema as Presenting Complication of Simultaneous Pancreas-Kidney Transplantation With Bladder Drainage
No abstract available (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - December 25, 2018 Category: OBGYN Tags: Case Report Source Type: research

Cervical Adenoid Basal Carcinoma: Clinicopathologic Features of 9 Cases With Reference to CK17 and Ki-67 Expression
Conclusions Adenoid basal carcinoma had characteristic morphological features, and the differential diagnosis of ABC from SCC is usually simple, based on morphology. In select cases, when histological findings are equivocal, the loss of CK17 expression in the squamous differentiation area, and a lower Ki-67 index in basal cell foci support ABC diagnosis. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - December 25, 2018 Category: OBGYN Tags: Case Series Source Type: research

Calcinosis Cutis of the Vulva: A Review
Idiopathic calcinosis cutis (CC) is an uncommon skin condition. Although it has been reported many times in the scrotum, it is exceedingly rare in the vulva. Most reports of vulvar CC are in children. Vulvar CC may be thought clinically to be inclusion cysts. Other causes of calcinosis such as autoimmune disease or alterations in serum calcium levels, potentially associated with malignancy, must be considered before considering a case as idiopathic. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - December 25, 2018 Category: OBGYN Tags: Original Research Articles: Vulva and Vagina Source Type: research

Anti-Inflammatory Effect of Surfactant Lipid in the Vaginal Mucosa: A Pilot Study
Conclusions This pilot study in healthy women demonstrates that calfactant reduces proinflammatory cytokines and increases anti-inflammatory cytokines in the vagina. We propose that calfactant may be an effective vaginal anti-inflammatory therapy for inflammatory vaginitis and similar disorders for which current therapy is ineffective. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - December 25, 2018 Category: OBGYN Tags: Original Research Articles: Vulva and Vagina Source Type: research

Fact or Fiction? Adipose-Derived Stem Cells and Platelet-Rich Plasma for the Treatment of Vulvar Lichen Sclerosus
Conclusions Current evidence is weak for ADSCs and/or PRP as treatment for vulvar LS. Further research is needed before recommending this therapy. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - December 25, 2018 Category: OBGYN Tags: Original Research Articles: Vulva and Vagina Source Type: research