Group A Streptococcal Vulvitis in Adult Women: Clinical Features and Association With Psoriasis
Conclusions In most adult women, GAS vulvitis is associated with a vaginal infection that may be asymptomatic. A bilateral, oozing, and edematous or fissured erythema involving the vulvar or anovulvar area is suggestive of GAS vulvitis. The association with psoriasis and the benefits of screening household members and sexual partners deserves further attention. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - October 1, 2019 Category: OBGYN Tags: Case Series Source Type: research

Acupuncture Augmentation of Lidocaine for Provoked, Localized Vulvodynia: A Feasibility and Acceptability Study
Conclusions In this early-phase research, acupuncture augmentation of lidocaine was acceptable. The study procedures, with modifications, may be feasible for future investigation. Both acupuncture techniques showed a favorable effect; however, the contribution to pain relief is undetermined. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - October 1, 2019 Category: OBGYN Tags: Original Research Articles: Vulva and Vagina Source Type: research

The Clinical Utility of the Vulvar Pain Assessment Questionnaire: A Pilot Study
Conclusions Patients with vulvar pain often endure a lengthy process of consulting multiple clinicians before securing care. The VPAQscreen was more than 80% accurate in predicting diagnosis at this specialty clinic and was useful in assisting patients with expressing symptoms. The applicability of the VPAQscreen in general practice is unknown, although it shows promise. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - October 1, 2019 Category: OBGYN Tags: Original Research Articles: Vulva and Vagina Source Type: research

Screening for Anal Cancer in Women With a History of Vulvar High-Grade Squamous Intraepithelial Lesions
Conclusions Women with vulvar HSIL have an increased risk of developing anal HSIL. Larger studies are needed to define optimal screening protocols as well as algorithms for management in high-risk populations. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - October 1, 2019 Category: OBGYN Tags: Original Research Article: Perianal and Anal Source Type: research

Distribution of High-Risk Human Papillomavirus Genotypes and Multiple Infections in Preneoplastic and Neoplastic Cervical Lesions of Unvaccinated Women: A Cross-sectional Study
Objective The aim of the study was to investigate the distribution of high-risk (HR) human papillomavirus (HPV) genotypes and the role of multiple infection in preneoplastic and neoplastic cervical lesions, according to histology, age, and the number of genotypes per infection. Materials and Methods Nine hundred eighty-eight women affected by known HPV-related cervical lesions and attending the European Institute of Oncology, Milan, Italy, from December 2006 to December 2014, were selected for a cross-sectional study. Prevalence of HPV genotypes was calculated by histology and the number of genotypes per infection. Un...
Source: Journal of Lower Genital Tract Disease - October 1, 2019 Category: OBGYN Tags: Original Research Articles: Cervix and HPV Source Type: research

Effect of an Electronic Health Record Decision Support Alert to Decrease Excess Cervical Cancer Screening
Conclusions An EHR clinical decision support alert does not decrease guideline-nonadherent cervical cancer screening. These data suggest efforts to optimize clinical decision support should be focused on other aspects of cervical cancer prevention. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - October 1, 2019 Category: OBGYN Tags: Original Research Articles: Cervix and HPV Source Type: research

Low-Risk Human Papillomavirus Types in Cervical Intraepithelial Neoplasia 2–3 and in Invasive Cervical Cancer Patients
Conclusions The prevalence of the LR-HPV in high-grade squamous intraepithelial lesion cervical lesions is low but is expected to increase in the future because of the expected decrease in CC caused by HPV types that are included in the bi-, quadri-, and nanovalent vaccine. The CIN 2–3 and CC patients with LR-HPV types and with negative HPV, challenge HPV screening sensitivity, which is based on a limited number of HR-HPV types. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - October 1, 2019 Category: OBGYN Tags: Original Research Articles: Cervix and HPV Source Type: research

Key Determinants of the Value of Random Cervical Biopsy at Colposcopy
Objective The aim of the study was to assess whether lower proportions of cervical intraepithelial neoplasia 2+ diagnosed by random biopsy are from lower cut points defining an abnormal colposcopic impression or obtaining only one random biopsy when colposcopic impression is normal. Methods We compared colposcopy experiences within Shanxi Province Cervical Cancer Screening Study (SPOCCS) (n = 1,383) and Shenzhen Cervical Cancer Screening Trial (SHENCCAST) (n = 631), which had instructive differences in the cut point defining an abnormal colposcopic impression. Results The proportion of CIN 2+ diagnosed by random bi...
Source: Journal of Lower Genital Tract Disease - October 1, 2019 Category: OBGYN Tags: Original Research Articles: Cervix and HPV Source Type: research

Zebras in Foreskin Dermatopathology: A Review
Conclusions We reviewed and discussed unusual benign and malignant dermatopathology conditions that can affect the foreskin. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - June 26, 2019 Category: OBGYN Tags: Review Source Type: research

Chlamydia Infection Among Digital Daters and Nondigital Daters
Conclusions Dating app users did not seem to have an increased risk of acquiring CT and for dating app users the seemingly well-established risk factor of having many partners was not valid. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - June 26, 2019 Category: OBGYN Tags: Original Research Articles: Vulva and Vagina Source Type: research

CD101 Topical Compared With Oral Fluconazole for Acute Vulvovaginal Candidiasis: A Randomized Controlled Trial
Conclusions CD101 3% gel and CD101 6% ointment were well tolerated and produced similar rates of clinical and mycological cure in patients with an acute, moderate-to-severe episode of VVC. However, cure rates for these 2 formulations and regimens of CD101 were lower than those in patients treated with fluconazole. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - June 26, 2019 Category: OBGYN Tags: Original Research Articles: Vulva and Vagina Source Type: research

Exploring Hygienic Behaviors and Vulvodynia
Conclusions Wearing tight-fitting jeans or pants and removing hair from the mons pubis area were associated with increased odds of vulvodynia. Research on how hygienic practices could influence vulvar pain in larger and more temporally addressed populations is warranted. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - June 26, 2019 Category: OBGYN Tags: Original Research Articles: Vulva and Vagina Source Type: research

Genomic Profiling of Vulvar Lichen Sclerosus Patients Shows Possible Pathogenetic Disease Mechanisms
Conclusions Although many providers may see a mother and daughter with vulvar LS, this condition is rarely seen in multiple family members who are available for genetic testing. This is the first report to detail genomic profiling related to a familial association of vulvar LS. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - June 26, 2019 Category: OBGYN Tags: Original Research Articles: Vulva and Vagina Source Type: research

The Female Genital Self-image Scale in Adult Women With Vulvar Lichen Sclerosus
Objective There is no agreed upon standard way to measure vulvar lichen sclerosus disease severity. The Female Genital Self-Image Scale (FGSIS) is a validated survey tool assessing female genital self-image and is positively correlated with women's sexual function. A lower score represents a negative genital self-image. We evaluated the FGSIS in women with vulvar lichen sclerosus. Methods Women with biopsy-proven lichen sclerosus and women presenting for routine gynecologic care without lichen sclerosus matched by age were surveyed with the 7-item FGSIS. National surveys of healthy women in the United States have show...
Source: Journal of Lower Genital Tract Disease - June 26, 2019 Category: OBGYN Tags: Original Research Articles: Vulva and Vagina Source Type: research

What Role Should Cytology Play in Cervical Cancer Screening?
No abstract available (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - June 26, 2019 Category: OBGYN Tags: Forum Source Type: research

Concordance of Self- and Clinician-Collected Anal Swabs to Detect Human Papillomavirus in a Sample of HIV-Negative Men
Conclusions Self-collected anorectal swab samples showed lower sensitivity but moderate to high specificity for detection of high-risk and vaccine-preventable HPV types compared with clinician-collected swab samples. Self-collection instructional details and the thoroughness of clinician collection of samples may have impacted sensitivity and specificity, suggesting a need to optimize and standardize instructions. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - June 26, 2019 Category: OBGYN Tags: Original Research Article: Perianal and Anal Source Type: research

Acceptability of Women Self-Sampling versus Clinician-Collected Samples for HPV DNA Testing: A Systematic Review
Conclusions Both methods of sampling were found to be acceptable to women. Self-sampling is cost-effective and could increase the screening coverage among underscreened populations. However, more information about the quality, reliability, and accuracy of self-sampling is needed to increase women's confidence about using to this method. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - June 26, 2019 Category: OBGYN Tags: Original Research Articles: Cervix and HPV Source Type: research

Tablet-Based Patient Education Regarding Human Papillomavirus Vaccination in Colposcopy Clinic
Objective The aim of this study was to use an electronic tablet–based education module to increase patient knowledge about human papillomavirus (HPV). Methods Patients presenting to an academic colposcopy clinic were first queried as to whether they had been infected with HPV. A quality improvement project was then conducted using a 4-question pretest assessing baseline knowledge about HPV and cancer, followed by a tablet-based education module and a 5-question posttest. Results Between June 2017 and January 2018, 119 patients participated in the tablet education. At their initial visit, only 50 (42.0%) of pa...
Source: Journal of Lower Genital Tract Disease - June 26, 2019 Category: OBGYN Tags: Original Research Articles: Cervix and HPV Source Type: research

ASCCP President 2019–2020 Vision
No abstract available (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - June 26, 2019 Category: OBGYN Tags: ASCCP News Source Type: research

Vulvovaginal Lichen Planus: A Disease in Need of Consensus-Based Clinicopathologic Diagnostic Criteria
No abstract available (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: Letters to the Editor Source Type: research

Reply to “Is Vulvovaginal Lichen Planus Associated With Squamous Cell Carcinoma?”
No abstract available (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: Letters to the Editor Source Type: research

Should We Always Biopsy in Clinically Evident Lichen Sclerosus?
Conclusions Reliance on biopsies solely to establish or exclude the diagnosis of LS is inadvisable. A good level of knowledge of the characteristic clinical features is imperative among gynecologists, dermatologists, and general practitioners. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: Benign Vulvovaginal Disorders Source Type: research

Impact of the Sampling Site in the Result of Wet Mount Microscopy
Conclusions There is some variation in the results according to the sampling site, which may be overcome by collecting 2 samples (anterior fornix and lower third of the vagina). (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: Benign Vulvovaginal Disorders Source Type: research

Mindfulness-Based Group Cognitive Behavior Therapy for Provoked Localized Vulvodynia: A Randomized Controlled Trial
Conclusions Mindfulness-based group cognitive behavior and education support group therapy are effective in reducing pain and distress. However, women in the M-gCBT program showed greater improvement in certain secondary outcomes, indicating that M-gCBT may offer some advantages in reducing distress associated with provoked localized vulvodynia. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: Benign Vulvovaginal Disorders Source Type: research

Vulvovaginal Discomfort Is Common in Both Premenopausal and Postmenopausal Women
Objectives We surveyed women from a primary care population to assess the prevalence of unreported vulvovaginal symptoms. Materials and Methods A random sample of women aged 18 to 84 years without a diagnosis of vulvovaginitis or vulvodynia in the past year were surveyed anonymously about prevalence and severity of vulvar and vaginal symptoms of itching, burning, irritation, vaginal discharge, vaginal dryness, and vulvovaginal pain in the past month. Women reporting at least 1 moderate-severe symptom were considered symptomatic. Demographic and clinical characteristics were compared between women with and without symp...
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: Benign Vulvovaginal Disorders Source Type: research

Descriptors of Vulvodynia: A Multisocietal Definition Consensus (International Society for the Study of Vulvovaginal Disease, the International Society for the Study of Women Sexual Health, and the International Pelvic Pain Society)
Conclusions The definitions of vulvodynia descriptors were determined by a multistaged process of discussion among health care providers with expertise in the pathophysiology, evaluation, and treatment of vulvodynia. The definitions were approved by the ISSVD, ISSWSH, and IPPS. It is recommended that these definitions of vulvodynia descriptors as well as the 2015 consensus terminology be used for the classification of vulvodynia. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: Benign Vulvovaginal Disorders Source Type: research

The Clinical Role of LASER for Vulvar and Vaginal Treatments in Gynecology and Female Urology: An ICS/ISSVD Best Practice Consensus Document
In this best practice document, we propose recommendations for the use of LASER for gynecologic and urologic conditions such as vulvovaginal atrophy, urinary incontinence, vulvodynia, and lichen sclerosus based on a thorough literature review. Most of the available studies are limited by their design; for example, they lack a control group, patients are not randomized, follow-up is short term, series are small, LASER is not compared with standard treatments, and most studies are industry sponsored. Because of these limitations, the level of evidence for the use of LASER in the treatment of these conditions remains low and ...
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: Benign Vulvovaginal Disorders Source Type: research

Should We Always Look Before We LEEP? A Discussion of the Pros and Cons of Colposcopic Biopsy Prior to Treatment
No abstract available (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: Forum Source Type: research

International Anal Neoplasia Society Guidelines for the Practice of Digital Anal Rectal Examination
Conclusions Digital Anal Rectal Examination is a cheap and potentially universally available technique, which has the potential to facilitate the early diagnosis of anal cancers, when they are most amenable to treatment. These guidelines provide a basis for teaching the technique and may be used as for evaluation research. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: Anal Disease Source Type: research

Evaluation of Folate Receptor-Mediated Cervical Dyeing as a Method for Detection of Cervical Lesions
Objectives The aim of the study was to evaluate the performance of a folate receptor–mediated tumor detection (FRD) assay for detection of cervical high-grade lesions. Materials and Method A total of 1504 patients with abnormal cytology and/or positive human papillomavirus (HPV) testing during primary screening from November 2014 to August 2015 were enrolled. The patients were recruited from the Peking University People's Hospital and 12 other hospitals. Folate receptor–mediated tumor detection was applied in all the patients before colposcopy to compare the detection rate, sensitivity, specificity, positi...
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: HPV-Associated Disease: Diagnosis and Management Source Type: research

Factors Related to Overtreatment in the See-and-Treat Approach: A Retrospective Multicentric Observational Study
Objective The aim of the study was to evaluate the association between colposcopic features, age, menopausal status, and overtreatment in women subjected to “see-and-treat” approach, to identify subgroups of patients in which this approach could be more appropriate. Materials and Methods Retrospective multicentric cohort study conducted on women older than 25 years, with a high-grade squamous cytological report and a visible squamocolumnar junction, in which colposcopy and the excisional procedure were performed at the same time without a previous cervical biopsy (see and treat). Overtreatment was defined ...
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: HPV-Associated Disease: Diagnosis and Management Source Type: research

Simple Hysterectomy for Cervical Cancer: Risk Factors for Failed Screening and Deviation From Screening Guidelines
Conclusions The most common cause of incidental cervical cancer at the time of simple hysterectomy was failure to properly adhere to screening guidelines. Less frequently, false-negative screening was the cause. No independent risk factor in either group was identified in this single institutional study. Illustrated is the importance of continuing education of surgeons about adequate screening in the preoperative evaluation for benign hysterectomy. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: HPV-Associated Disease: Diagnosis and Management Source Type: research

Reimbursement Incentives to Improve Adherence to Follow-Up of Cervical Cancer Cytology Screening Results in Peru
Objective The purpose of this study was to determine Peruvian women's attitudes toward novel reimbursement incentives used to improve adherence to obtaining cervical cytology test results. Materials and Methods Women presenting for cervical cancer screening in Peru completed a 34-item Investigational Review Board-approved questionnaire. The questionnaire determined their attitudes toward various reimbursement incentives to improve adherence to obtaining cervical cytology results. Descriptive statistics, generalized linear models, and Kruskal-Wallis tests were used in the analyses. Results Completed questionnaires w...
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: HPV-Associated Disease: Diagnosis and Management Source Type: research

Observed Colposcopy Practice in US Community-Based Clinics: The Retrospective Control Arm of the IMPROVE-COLPO Study
Objective The aim of the study was to characterize colposcopy practice and management of women with cervical abnormalities in US community-based clinics. Materials and Methods IMPROVE-COLPO was a 2-arm study of colposcopy patients with an abnormal screening result. The prospective arm recruited women to undergo examination with a commercial digital colposcope. The retrospective-control arm collected data (chart review) from previous colposcopies performed using standard equipment and methods. From the retrospective arm, we analyzed referral trends, colposcopy and biopsy practice, and management patterns. Results We...
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: HPV-Associated Disease: Diagnosis and Management Source Type: research

Cervical, Vaginal, and Vulvar Cancer Costs Incurred by the Medicaid Program in Publicly Insured Patients in Texas
Conclusions The direct medical costs associated with cervical, vaginal, and vulvar cancers in Texas Medicaid were substantial in the first 2 years after cancer diagnosis, but dual eligibility for Medicare coverage attenuated Medicaid costs. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: HPV-Associated Disease: Diagnosis and Management Source Type: research

Guidelines for Cervical Cancer Screening in Immunosuppressed Women Without HIV Infection
The objective of this report was to summarize current knowledge of CC, squamous intraepithelial lesions, and human papillomavirus (HPV) infection in non-HIV immunocompromised women to determine best practices for CC surveillance in this population and provide recommendations for screening. We evaluated those with solid organ transplant, hematopoietic stem cell transplant, and a number of autoimmune diseases. A panel of health care professionals involved in CC research and care was assembled to review and discuss existing literature on the subject and come to conclusions about screening based on available evidence and expe...
Source: Journal of Lower Genital Tract Disease - March 23, 2019 Category: OBGYN Tags: HPV-Associated Disease: Diagnosis and Management Source Type: research

Why Do Women Get Cervical Cancer in an Organized Screening Program in Canada?
Conclusions Although nonparticipation in screening is the greatest factor associated with cervical cancer diagnosis, failure of cervical cytology to detect cytologic abnormalities in women 2 to 3 and 3 to 5 years before diagnosis is of concern. Efforts must be directed to recruitment of women for screening as well as improving the sensitivity of screening tests to detect existing abnormalities. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - January 1, 2019 Category: OBGYN Tags: Original Research Articles: Cervix and HPV Source Type: research

Response to “Immediate Loop Electrode Excisional Procedure for High-Grade Cervical Cytology: One Size Fits All?”
No abstract available (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - December 25, 2018 Category: OBGYN Tags: Letters to the Editor Source Type: research

Immediate Loop Electrode Excisional Procedure for High-Grade Cervical Cytology: One Size Fits All?
No abstract available (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - December 25, 2018 Category: OBGYN Tags: Letters to the Editor Source Type: research

Vulvar Edema as Presenting Complication of Simultaneous Pancreas-Kidney Transplantation With Bladder Drainage
No abstract available (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - December 25, 2018 Category: OBGYN Tags: Case Report Source Type: research

Cervical Adenoid Basal Carcinoma: Clinicopathologic Features of 9 Cases With Reference to CK17 and Ki-67 Expression
Conclusions Adenoid basal carcinoma had characteristic morphological features, and the differential diagnosis of ABC from SCC is usually simple, based on morphology. In select cases, when histological findings are equivocal, the loss of CK17 expression in the squamous differentiation area, and a lower Ki-67 index in basal cell foci support ABC diagnosis. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - December 25, 2018 Category: OBGYN Tags: Case Series Source Type: research

Calcinosis Cutis of the Vulva: A Review
Idiopathic calcinosis cutis (CC) is an uncommon skin condition. Although it has been reported many times in the scrotum, it is exceedingly rare in the vulva. Most reports of vulvar CC are in children. Vulvar CC may be thought clinically to be inclusion cysts. Other causes of calcinosis such as autoimmune disease or alterations in serum calcium levels, potentially associated with malignancy, must be considered before considering a case as idiopathic. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - December 25, 2018 Category: OBGYN Tags: Original Research Articles: Vulva and Vagina Source Type: research

Anti-Inflammatory Effect of Surfactant Lipid in the Vaginal Mucosa: A Pilot Study
Conclusions This pilot study in healthy women demonstrates that calfactant reduces proinflammatory cytokines and increases anti-inflammatory cytokines in the vagina. We propose that calfactant may be an effective vaginal anti-inflammatory therapy for inflammatory vaginitis and similar disorders for which current therapy is ineffective. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - December 25, 2018 Category: OBGYN Tags: Original Research Articles: Vulva and Vagina Source Type: research

Fact or Fiction? Adipose-Derived Stem Cells and Platelet-Rich Plasma for the Treatment of Vulvar Lichen Sclerosus
Conclusions Current evidence is weak for ADSCs and/or PRP as treatment for vulvar LS. Further research is needed before recommending this therapy. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - December 25, 2018 Category: OBGYN Tags: Original Research Articles: Vulva and Vagina Source Type: research

Localized Provoked Vulvodynia: Association With Nerve Growth Factor and Transient Receptor Potential Vanilloid Type 1 Genes Polymorphisms
Conclusions Our results suggest novel genetic susceptibility to primary LPV associated with specific alleles in genes TRPV1 and NGF and propose the rs222747 “C” allele of TRPV1 as a common genetic predisposition for other pain syndromes. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - December 25, 2018 Category: OBGYN Tags: Original Research Articles: Vulva and Vagina Source Type: research

Should Self-Sampling Be an Option for Women in the United States?
No abstract available (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - December 25, 2018 Category: OBGYN Tags: Forum Source Type: research

Improved anal Cytology Sampling: Tush Brush Compared With Dacron Swab
Conclusions Anal cytology AUCROC, sensitivity, and specificity in detecting anal neoplasia were greater using the TB when compared with the DS. A novel anal cytology sampling device designed specifically to increase the detection of anal neoplasia would be clinically beneficial. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - December 25, 2018 Category: OBGYN Tags: Original Research Article: Perianal and Anal Source Type: research

Comparison of Electrosurgical Devices for Cervical Conization: Novel Monopolar Scalpel (VIO) Versus Ultrasonic Scalpel
Conclusions Considering short operating time and less postoperative bleeding, VIO was preferred to HS. However, the excessive coagulation in VIO is considered to lead to cervical stenosis. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - December 25, 2018 Category: OBGYN Tags: Original Research Articles: Cervix and HPV Source Type: research

Onclarity Human Papillomavirus Extended Genotyping in the Management of Cervical Intraepithelial Neoplasia 2+ Lesions
Conclusions This study showed that the evaluation of the HPV genotype persistence may represent a valid option to monitor patients treated for CIN 2+ lesions, because relapses were detected only in patients with persistence of the same genotype detected at baseline. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - December 25, 2018 Category: OBGYN Tags: Original Research Articles: Cervix and HPV Source Type: research

Expression of Psoriasin in Human Papillomavirus–Induced Cervical High-Grade Squamous Intraepithelial Lesions
Conclusions In this study of AMP expression in human papillomavirus–induced HSIL, we observed lower psoriasin levels before surgery compared with after treatment, when both mRNA and protein levels were similar to healthy controls. Interleukin 8, on the other hand, was increased before treatment, indicating an inflammatory response. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - December 25, 2018 Category: OBGYN Tags: Original Research Articles: Cervix and HPV Source Type: research