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Bacterial vaginosis in a subfertile population undergoing fertility treatments: a prospective cohort study
ConclusionBacterial vaginosis does not significantly impact ongoing pregnancy rates but could affect miscarriage rates. (Source: Journal of Assisted Reproduction and Genetics)
Source: Journal of Assisted Reproduction and Genetics - December 13, 2023 Category: Reproduction Medicine Source Type: research

Expression of mitochondrial transcription factor A in granulosa cells: implications for oocyte maturation and in vitro fertilization outcomes
ConclusionTFAM was detected in the cytoplasm of human ovarian granulosa cells. Women with moderate TFAM expression demonstrate enhanced outcomes in IVF. (Source: Journal of Assisted Reproduction and Genetics)
Source: Journal of Assisted Reproduction and Genetics - December 11, 2023 Category: Reproduction Medicine Source Type: research

Reproductive outcomes of single frozen-thawed embryo transfer in patients with endometriosis after preimplantation genetic testing
ConclusionPregnancy outcomes using frozen embryos after PGT in patients with endometriosis did not differ from those in other women experiencing infertility. However, endometriosis may affect the quality of oocytes, resulting in a higher rate of aneuploidy. (Source: Journal of Assisted Reproduction and Genetics)
Source: Journal of Assisted Reproduction and Genetics - December 11, 2023 Category: Reproduction Medicine Source Type: research

First case of dichorionic diamniotic triplet pregnancy after single blastocyst transfer
AbstractMultiple pregnancies are associated with significant maternal, fetal, and neonatal risks, including prematurity, low birth weight, pre-eclampsia, anemia, postpartum hemorrhage, intrauterine growth restriction, neonatal morbidity, and increased neonatal and infant mortality rates. Assisted reproductive technology (ART) treatments should prioritize efforts to reduce such events, resisting patient demand for the transfer of multiple embryos at each transfer to increase success rates. Extended culture, embryo selection, and single blastocyst transfer can mitigate the risk of high-order multiple pregnancies. Intriguingl...
Source: Journal of Assisted Reproduction and Genetics - December 11, 2023 Category: Reproduction Medicine Source Type: research

Correction to: The HERA (Hyper ‑response Risk Assessment) Delphi consensus for the management of hyper‑responders in in vitro fertilization
(Source: Journal of Assisted Reproduction and Genetics)
Source: Journal of Assisted Reproduction and Genetics - December 11, 2023 Category: Reproduction Medicine Source Type: research

The role of the intrinsic pathway of apoptosis in human ejaculated sperm damage under a state of scrotal heat stress
ConclusionLong-term exposure to scrotal hyperthermia in real-life situations is sufficient to reduce sperm quality in humans. The thermal stress directly induces the oxidative stress cascade in ejaculated sperm, affecting the plasma membrane fluidity, mitochondrial homeostasis, and sperm DNA integrity. (Source: Journal of Assisted Reproduction and Genetics)
Source: Journal of Assisted Reproduction and Genetics - December 8, 2023 Category: Reproduction Medicine Source Type: research

OneGene PGT: comprehensive preimplantation genetic testing method utilizing next-generation sequencing
ConclusionOneGene PGT is a comprehensive, robust, and cost-effective method that can be established for any gene of interest. The technique is particularly suitable for common monogenic diseases, which can be performed based on a universal laboratory protocol without the need for set-up or pre-testing. (Source: Journal of Assisted Reproduction and Genetics)
Source: Journal of Assisted Reproduction and Genetics - December 8, 2023 Category: Reproduction Medicine Source Type: research