Are Psychiatric Disorders Brain Diseases? —A New Look at an Old Question
This Viewpoint discusses whether psychiatric disorders are diseases of the brain. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - February 28, 2024 Category: Psychiatry Source Type: research
Psychomotor Slowing in Psychosis and Inhibitory Repetitive Transcranial Magnetic Stimulation
This randomized clinical trial compares repetitive transcranial magnetic stimulation with intermittent theta burst stimulation, sham, and no treatment for reducing psychomotor slowing in individuals with psychosis. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - February 28, 2024 Category: Psychiatry Source Type: research
Cognitive Function and Variability in Patients With First-Episode Psychosis
This systematic review and meta-analysis investigates cognitive function and variability before initiation of antipsychotic medication in patients with first-episode psychosis compared with controls. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - February 28, 2024 Category: Psychiatry Source Type: research
Prioritizing Maternal Mental Health in Addressing Morbidity and Mortality
This Special Communication reviews data about associations between maternal mortality and perinatal mental conditions, social determinants of health, suicide and addictive disorders, access limitations, and prenatal stress and describes efforts involving cross-disciplinary education and intervention sites and models. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - February 21, 2024 Category: Psychiatry Source Type: research
Lifetime Suicide Attempts in Otherwise Psychiatrically Healthy Individuals
This cross-sectional study estimates the proportion of US adults with lifetime suicide attempts whose first attempt occurred without or preceded the diagnosis of a psychiatric disorder. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - February 21, 2024 Category: Psychiatry Source Type: research
Acupuncture for Combat-Related Posttraumatic Stress Disorder
This randomized clinical trial assesses the effectiveness of verum vs sham acupuncture in reducing severity of symptoms in combat-related posttraumatic stress disorder. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - February 21, 2024 Category: Psychiatry Source Type: research
Ethnoracial Risk Variation Across the Psychosis Continuum in the US
This systematic review and meta-analysis investigates if ethnoracial groups in the US differ in risk of schizophrenia and other psychotic disorders, clinical high risk for psychosis, and psychotic symptoms and experiences. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - February 21, 2024 Category: Psychiatry Source Type: research
AI-Based Brain Aging Patterns in Cognitively Unimpaired Individuals
This cohort study investigates the patterns of morphological brain changes that are reproducibly detectable with artificial intelligence (AI) in cognitively unimpaired populations and their genetic, clinical, lifestyle, and cognitive features. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - February 14, 2024 Category: Psychiatry Source Type: research
Variations in Suicide Risk and Risk Factors After Hospitalization for Depression in Finland, 1996-2017
This cohort study examines the absolute risk and risk factors for suicide in hospitalized patients with depression starting from the first days after discharge up to 2 years and evaluates whether the size of relative risk by factor displays temporal patterns over consecutive phases of follow-up. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - February 14, 2024 Category: Psychiatry Source Type: research
ENIGMA Brain Morphometry in CHR-P —Risk Enrichment and Antipsychotics—Reply
In Reply We thank Raballo and colleagues for their insightful comments on our article. We appreciate their recognition of the substantial sample size of individuals at clinical high risk for psychosis, provided by the ENIGMA Consortium working group, which significantly enhanced the statistical robustness of our study design. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - February 14, 2024 Category: Psychiatry Source Type: research
ENIGMA Brain Morphometry in CHR-P —Risk Enrichment and Antipsychotics
To the Editor The study of the ENIGMA Clinical High Risk for Psychosis Working Group adopted a case-control design to address a crucial question in the field, ie, whether brain morphometric changes are associated with the severity of positive symptoms or subsequent transition to a psychotic disorder. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - February 14, 2024 Category: Psychiatry Source Type: research
Parameter Space and Potential for Biomarker Development in 25 Years of fMRI Drug Cue Reactivity
This systematic review summarizes the state of the field of functional magnetic resonance imaging (fMRI) drug cue reactivity, assesses their potential for biomarker development, and outlines a clear process for biomarker qualification to guide future research and validation efforts (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - February 7, 2024 Category: Psychiatry Source Type: research
Sex-Specific Pathways From Prenatal Maternal Inflammation to Adolescent Depressive Symptoms
This cohort study evaluates associations between maternal inflammatory biomarkers in pregnancy and depressive symptoms in their offspring. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - February 7, 2024 Category: Psychiatry Source Type: research
The Reliability of Traumatic and Adverse Experiences —Reply
In Reply We thank Dr Weems for his interest in our study. In a cohort study of 1196 individuals followed up to age 40 years, we found that the subjective experience of childhood maltreatment measured through retrospective self-report at age 29 years was associated with the number of subsequent follow-up phases when participants met the criteria for a depression or anxiety diagnosis, whereas the objective experience measured through official court records was not. Current and lifetime psychopathology at the time the subjective experience was assessed and explained its association with the later course of emotional disorders...
Source: JAMA Psychiatry - February 7, 2024 Category: Psychiatry Source Type: research
The Reliability of Traumatic and Adverse Experiences
To the Editor Danese and Widom reported a study of children aged 6 years who had a court-substantiated case of abuse and demographically matched children aged 6 years who did not. When the children were aged 26 years, their subjective report of exposure to abuse was assessed. The study includes data on the long-term reliability between the objective reports and the subjective reports (at age 26 years) in eTable 1 in Supplement 1 (overall, Cohen k = 0.25; physical abuse, Cohen k = 0.09; sexual abuse, Cohen k = 0.17; and neglect, Cohen k = 0.32). The Cohen k results suggest low reliability over the course of...
Source: JAMA Psychiatry - February 7, 2024 Category: Psychiatry Source Type: research
