Concerns Regarding Strength of Conclusions in Systematic Review and Meta-Analysis of Neuroradiological Abnormalities in First-Episode Psychosis
To the Editor I recently cared for a patient with first-episode psychosis (FEP) with an otherwise normal neurological examination. The provocative meta-analysis by Blackman et al prompted me to reflect on the role of magnetic resonance imaging (MRI) in such cases. The authors ’ analysis suggests that 1 in 18 patients with FEP had a “clinically relevant abnormality,” and advocate for routine MRI scans in initial assessments. However, the study’s findings warrant reversal of the resultant implications for 3 critical reasons. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - November 15, 2023 Category: Psychiatry Source Type: research
Concerns Regarding Strength of Conclusions in Systematic Review and Meta-Analysis of Neuroradiological Abnormalities in First-Episode Psychosis
To the Editor We read with great interest the recent article by Blackman et al, which concludes that approximately 6% of patients with first-episode psychosis (FEP) have a clinically relevant magnetic resonance imaging (MRI) finding, supporting MRI as a potentially “mandatory” part of the initial assessment for FEP. We highlight 3 points that raise questions regarding the strength of this study’s conclusions. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - November 15, 2023 Category: Psychiatry Source Type: research
Concerns Regarding Strength of Conclusions in Systematic Review and Meta-Analysis of Neuroradiological Abnormalities in First-Episode Psychosis
To the Editor We believe that Blackman et al have overestimated the usefulness of magnetic resonance imaging (MRI) due to their definition of “clinically relevant.” What is considered clinically relevant may have changed between 1991 and 2021 (the time range of included studies), affecting radiologist reports and referral rates, and thus, prevalence estimates. More importantly, their definition is removed from the primary reason why p hysicians order neuroimaging in first-episode psychosis (FEP), that is, to exclude structural and potentially reversible causes of psychosis. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - November 15, 2023 Category: Psychiatry Source Type: research
Neighborhood Disadvantage and Autism Spectrum Disorder in a Population With Health Insurance
This cohort study examines data for children with health insurance to gauge the association between a diagnosis of autism spectrum disorder and neighborhood disadvantage at birth and determine any potential effect modification by maternal and child demographic characteristics. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - November 15, 2023 Category: Psychiatry Source Type: research
Public Sector Learning Health Care Systems
This Viewpoint discusses the need for integrating basic, clinical, and epidemiological science into behavioral health care delivery to develop more scalable and sustainable learning health care systems and improve population health and patient experience, reduce costs, and promote the well-being of the health care workforce. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - November 8, 2023 Category: Psychiatry Source Type: research
Associations Between Neuromelanin-Sensitive MRI and Psychosis in Antipsychotic-Free Individuals
This cross-sectional study evaluates findings from neuromelanin-sensitive magnetic resonance imaging, a proxy measure of dopamine function, to determine the association between contrast and psychosis severity in antipsychotic-free individuals in the psychosis spectrum and evaluate its predictive ability. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - November 8, 2023 Category: Psychiatry Source Type: research
Correlates of Risk for Disinhibited Behaviors in the Million Veteran Program Cohort
This cohort study investigates the correlates of risk for disinhibited behaviors using electronic health record data of individuals in the Million Veteran Program. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - November 8, 2023 Category: Psychiatry Source Type: research
Notice of Retraction: Worthington MA, et al. Dynamic Prediction of Outcomes for Youth at Clinical High Risk for Psychosis: A Joint Modeling Approach. JAMA Psychiatry. 2023;80(10):1017-1025.
To the Editor In consulting with another group attempting to replicate our analyses, we have identified a coding error in the joint modeling analyses in our article, “Dynamic Prediction of Outcomes for Youth at Clinical High Risk for Psychosis: A Joint Modeling Approach,” published online on August 2, 2023, and in the October 2023 issue of JAMA Psychiatry. Specifically, the converter by time interaction term used in the feature selection phase of the longitu dinal mixed-effects analyses was mistakenly retained in the longitudinal mixed-effects component of the joint models, but only the time effect should have been use...
Source: JAMA Psychiatry - November 2, 2023 Category: Psychiatry Source Type: research
Perinatal Mental Health Outcomes Following Natural Disasters
This Viewpoint discusses mental health outcomes associated with natural disaster –related stressors during the perinatal period. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - November 1, 2023 Category: Psychiatry Source Type: research
Patterns of Neural Network Functional Connectivity Associated With Mania/Hypomania and Depression Risk
This cross-sectional study evaluates neural responses associated with risk of mania/hypomania and depression in 3 independent test samples. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - November 1, 2023 Category: Psychiatry Source Type: research
Genetic Liability to Posttraumatic Stress Disorder Symptoms and Its Association With Cardiometabolic and Respiratory Outcomes
This genetic association study uses electronic health record data to investigate the association between polygenic score of posttraumatic stress disorder symptom severity and clinical diagnoses and laboratory tests. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - November 1, 2023 Category: Psychiatry Source Type: research
Author Name Change
In the Original Investigation titled “Association of Pharmacological Treatments and Hospitalization and Death in Individuals With Amphetamine Use Disorders in a Swedish Nationwide Cohort of 13 965 Patients,” published January 4, 2023, the first author’s last name changed after publication from Heikkinen to Hartikainen. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - November 1, 2023 Category: Psychiatry Source Type: research
JAMA Psychiatry
Mission Statement: JAMA Psychiatry strives to publish original, state-of-the-art studies and commentaries of general interest to clinicians and researchers in psychiatry, mental health, behavioral science, and allied fields. The journal seeks to inform its readers, to stimulate discussion into the nature, causes, treatment, and public health importance of mental illness, and to promote equity and justice for those affected by mental illness and for society. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - November 1, 2023 Category: Psychiatry Source Type: research
Treating Climate and Nature Crisis as a Global Health Emergency
Over 200 health journals call on the United Nations, political leaders, and health professionals to recognize that climate change and biodiversity loss are one indivisible crisis and must be tackled together to preserve health and avoid catastrophe. This overall environmental crisis is now so severe as to be a global health emergency. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - October 25, 2023 Category: Psychiatry Source Type: research
Ketamine for Depression —Knowns, Unknowns, Possibilities, Barriers, and Opportunities
This Viewpoint discusses ketamine and its new and experimentally investigated on- and off-label indications that span different medical disciplines. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - October 25, 2023 Category: Psychiatry Source Type: research
