Addressing the Mental Health Crisis in Youth
This Viewpoint examines whether increased anxiety and depression among youth is a true epidemic of psychiatric disorders or a reflection of sociopolitical adversity and disorganization. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - June 21, 2023 Category: Psychiatry Source Type: research

Effect of Cognitive Behavioral Therapy for Insomnia on Alcohol Treatment Outcomes
This randomized clinical trial assesses the efficacy of cognitive behavioral therapy for insomnia in veterans receiving treatment for alcohol use disorder. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - June 21, 2023 Category: Psychiatry Source Type: research

Effectiveness of a Lifestyle Intervention for People With a Severe Mental Illness in Dutch Outpatient Mental Health Care
This randomized clinical trial evaluates the effectiveness of a group-based lifestyle intervention among people with severe mental illness in outpatient treatment settings compared with treatment as usual. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - June 21, 2023 Category: Psychiatry Source Type: research

Tailoring Psychiatric Neuroimaging to Translational Goals
This Viewpoint discusses tailoring psychiatric neuroimaging paradigms toward clear translational and practical end goals in an effort to focus resources, improve reproducibility, and accelerate neuroimaging ’s clinical utility. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - June 14, 2023 Category: Psychiatry Source Type: research

Clinical Promise of Brain-Phenotype Modeling
This Review explores explanations for the as yet limited practical utility of brain-phenotype modeling and proposes a path forward to fulfill this clinical potential. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - June 14, 2023 Category: Psychiatry Source Type: research

T-SEM of 13 Major Psychiatric Disorders for Cross-Disorder Risk and Drug Repurposing
This genetic association study identifies gene expression patterns underlying genetic convergence and divergence across psychiatric disorders along with existing pharmacological interventions that target these genes using transcriptome-wide structural equation modeling (T-SEM). (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - June 14, 2023 Category: Psychiatry Source Type: research

Acceptability, Tolerability, and Treatment Effects of Probiotics as Adjunctive Treatment in Depression
This pilot randomized clinical trial evaluates acceptability and tolerability data and estimates of intervention effect size for probiotics as adjunctive treatment for patients with major depressive disorder. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - June 14, 2023 Category: Psychiatry Source Type: research

Precision Neuroimaging for Localization-Related Psychiatry
This Viewpoint describes how precision functional mapping may be helpful for associating neuroanatomical regions with specific psychiatric disorders. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - June 7, 2023 Category: Psychiatry Source Type: research

Internet-Delivered Cognitive Behavioral Therapy for Anxiety and Depression in University Students
This prespecified secondary analysis of a randomized clinical trial discusses the development of an individualized treatment rule using machine learning methods for guided vs self-guided internet-delivered cognitive behavioral therapy based on a rich set of baseline predictors. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - June 7, 2023 Category: Psychiatry Source Type: research

Genetic Nurture and Depression and Neuroticism Through Polygenic Scores
This cross-sectional study used linear mixed modeling of polygenic scores to estimate the association of genetic nurture across a range of parental traits with offspring lifetime depression and neuroticism. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - June 7, 2023 Category: Psychiatry Source Type: research

JAMA Psychiatry
Mission Statement:  JAMA Psychiatry strives to publish original, state-of-the-art studies and commentaries of general interest to clinicians and researchers in psychiatry, mental health, behavioral science, and allied fields. The journal seeks to inform its readers, to stimulate discussion into the nature, causes, treatment, and public health importance of mental illness, and to promote equity and justice for those affected by mental illness and for society. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - June 1, 2023 Category: Psychiatry Source Type: research

Errors in Figures
This article has been corrected online. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - June 1, 2023 Category: Psychiatry Source Type: research

Extrapharmacological Safety Topics in Psychedelic-Assisted Psychotherapy
This Viewpoint proposes methods for optimizing patient and therapist safety during psychedelic-assisted psychotherapy. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - May 31, 2023 Category: Psychiatry Source Type: research

Spiritual, Existential, Religious, and Theological Components in Psychedelic-Assisted Therapies
This Special Communication argues for the integration of spiritual, existential, religious, and theological components within psychedelic-assisted therapy based on the prevalence and importance of relevant experiences in psychedelic-assisted therapy. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - May 31, 2023 Category: Psychiatry Source Type: research

Neuroinflammation After COVID-19 With Persistent Depressive and Cognitive Symptoms
This case-control study uses positron emission tomography to compare translocator protein distribution volume, a quantitative marker of gliosis, in brain regions of interest between healthy persons and persons with persistent depressive and cognitive symptoms after mild to moderate acute COVID-19 infection. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - May 31, 2023 Category: Psychiatry Source Type: research