Social Deprivation and Population Density Trajectories Before and After Psychotic Disorder Diagnosis
This case-control study examines whether patients diagnosed with psychotic disorder or nonpsychotic bipolar disorder differed from a control group in their deprivation and population density trajectories. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - September 6, 2023 Category: Psychiatry Source Type: research
Gabapentin Use With Buprenorphine Initiation for Opioid Use Disorder
This case-control study with crossover analysis assesses the differences between patients receiving and not receiving gabapentin alongside buprenorphine in the treatment of opioid use disorder and the drug-related poisoning risk associated with gabapentin. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - September 6, 2023 Category: Psychiatry Source Type: research
Efficacy and Safety of Antidepressants in Patients With Comorbid Depression and Medical Diseases
This systematic review and meta-analysis assesses all available evidence for use of antidepressants in depression comorbid with medical diseases. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - September 6, 2023 Category: Psychiatry Source Type: research
Substance Use Disorder and Health Outcomes in COVID-19 —The Need for a Better Research Method to Determine Substance Use Exposure—Reply
In Reply We thank Christian et al for raising concerns that (1) chronic diseases, rather than substance use disorder (SUD), may be more directly responsible for adverse outcomes of COVID-19 infection and (2) SUD itself can cause chronic somatic and mental health disorders. Both concerns are valid and important. These suggest new directions for research to describe the relative impact of chronic diseases and SUD on outcomes of COVID-19 infection. We agree that a better understanding of how medications prescribed for opioid use disorder (eg, methadone or buprenorphine) alter COVID-19 risk among persons with this SUD would be...
Source: JAMA Psychiatry - September 1, 2023 Category: Psychiatry Source Type: research
JAMA Psychiatry
Mission Statement: JAMA Psychiatry strives to publish original, state-of-the-art studies and commentaries of general interest to clinicians and researchers in psychiatry, mental health, behavioral science, and allied fields. The journal seeks to inform its readers, to stimulate discussion into the nature, causes, treatment, and public health importance of mental illness, and to promote equity and justice for those affected by mental illness and for society. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - September 1, 2023 Category: Psychiatry Source Type: research
Error in Additional Contributions
This article has been corrected online. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - September 1, 2023 Category: Psychiatry Source Type: research
Error in Key Points
This article has been corrected onlin e. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - September 1, 2023 Category: Psychiatry Source Type: research
Prenatal Antidepressant Exposure and Offspring Brain Morphologic Trajectory
This cohort study examines whether intrauterine exposure to selective serotonin reuptake inhibitors and prenatal or postnatal depressive symptoms are associated with brain morphologic trajectory in offspring. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - August 30, 2023 Category: Psychiatry Source Type: research
Prefrontal Cortical Somatostatin Neurons in Schizophrenia
This case-control study examines mRNA levels of somatostatin (SST) in the dorsolateral prefrontal cortex of postmortem brain specimens from patients with schizophrenia, bipolar disorder, and major depression disorder to assess whether alterations in SST levels are diagnosis specific and associated with cognitive dysfunction. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - August 30, 2023 Category: Psychiatry Source Type: research
Brain Networks and Adolescent Alcohol Use
This cohort study evaluates neuromarkers associated with alcohol use among adolescents. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - August 30, 2023 Category: Psychiatry Source Type: research
Prefrontal γ-Aminobutyric Acid Levels in Never-Medicated Individuals With Chronic Schizophrenia
This cross-sectional study analyzes spectroscopy data for long-term, never-medicated patients with schizophrenia to examine their levels of γ-aminobutyric acid (GABA) compared with those of healthy controls. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - August 30, 2023 Category: Psychiatry Source Type: research
Maternal Depression, SSRI Use, and Child Brain Trajectories
Maternal depression in pregnancy is common, and selective serotonin reuptake inhibitors (SSRIs) are the most frequently prescribed antidepressant medications used for its treatment. Preclinical studies have shown that gestational SSRI exposure may be adversely associated with offspring brain and behavioral development. In human populations, however, the effects of untreated maternal depression in pregnancy are of equal concern, and while SSRIs are considered generally safe, weighing the risks of medication exposure to the fetus vs the risk of maternal depression has remained a complex puzzle. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - August 30, 2023 Category: Psychiatry Source Type: research
Addressing Global Environmental Challenges to Mental Health Using Population Neuroscience
This narrative review discusses how the changing environment can influence the brain, behavior, and mental illness. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - August 23, 2023 Category: Psychiatry Source Type: research
Implications of the Network Theory for the Treatment of Mental Disorders
This secondary analysis of a randomized clinical trial evaluates 4 treatment-related hypotheses by developing a new longitudinal network model and analyzing data from the clinical trial on the treatment of patients with chronic depression. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - August 23, 2023 Category: Psychiatry Source Type: research
Written Exposure Therapy vs Prolonged Exposure Therapy in the Treatment of PTSD
This randomized clinical trial compares treatment outcomes for written exposure therapy and prolonged exposure therapy among veterans diagnosed with posttraumatic stress disorder. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - August 23, 2023 Category: Psychiatry Source Type: research
