SSRIs in Pregnancy —What Offspring Brain Volumes Can and Cannot Tell Us
To the Editor We read with great interest the publication of Koc and colleagues on prenatal exposure to selective serotonin reuptake inhibitors (SSRIs) and offspring brain trajectories. We applaud the authors for their innovative and well-executed study using data from a prospective population-based cohort, adjusting for confounders, including different comparator groups, and applying advanced neuroimaging techniques and statistical modeling. The authors showed that prenatal SSRI exposure was associated with about 3% reduced brain volumes of regions involved in emotional regulation in offspring. They also demonstrated mino...
Source: JAMA Psychiatry - January 10, 2024 Category: Psychiatry Source Type: research

Error in Figure 1
This article has been corrected. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - January 10, 2024 Category: Psychiatry Source Type: research

The Rapidly Shifting Ketamine Landscape in the US
This Viewpoint discusses changes in the use of ketamine as a medical therapeutic and a recreational substance, the potential risks of use, and the need for increased research and surveillance. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - January 3, 2024 Category: Psychiatry Source Type: research

Home-Use Transcranial Direct Current Stimulation for the Treatment of a Major Depressive Episode
This randomized clinical trial evaluates the efficacy of home-use transcranial direct current stimulation, combined or not with a digital psychological intervention, vs sham for the treatment of major depression. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - January 3, 2024 Category: Psychiatry Source Type: research

Online Racial Discrimination, Suicidal Ideation, and Traumatic Stress in Black Adolescents
This cross-sectional study examines data from the National Survey of Critical Digital Literacy for Black adolescents to gauge the direct and indirect associations between online racial discrimination and suicidal ideation through posttraumatic stress disorder symptoms. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - January 3, 2024 Category: Psychiatry Source Type: research

JAMA Psychiatry
Mission Statement:  JAMA Psychiatry strives to publish original, state-of-the-art studies and commentaries of general interest to clinicians and researchers in psychiatry, mental health, behavioral science, and allied fields. The journal seeks to inform its readers, to stimulate discussion into the nature, causes, treatment, and public health importance of mental illness, and to promote equity and justice for those affected by mental illness and for society. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - January 1, 2024 Category: Psychiatry Source Type: research

From Complexity to Precision —Charting Decision-Making Through Normative Modeling
This Viewpoint synthesizes data-driven and theory-driven approaches to normative modeling. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - December 27, 2023 Category: Psychiatry Source Type: research

Benzodiazepine Use During Pregnancy and Risk of Miscarriage
This case-time-control study evaluates the association between benzodiazepine use during pregnancy and risk of miscarriage. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - December 27, 2023 Category: Psychiatry Source Type: research

Sociocultural Risk and Resilience in the Context of Adverse Childhood Experiences
This cohort study examines 4 waves of data from the Boricua Youth Study to determine what sociocultural resilience factors in childhood are associated with better young adult mental health in the context of adverse childhood experiences. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - December 27, 2023 Category: Psychiatry Source Type: research

Error in Display of Author Name
This article was corrected online. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - December 27, 2023 Category: Psychiatry Source Type: research

Population Salutogenesis
This Viewpoint discusses the potential of salutogenesis, or emphasis on health- and wellness-promoting practices, as a public health approach to mitigate increasing levels of mental illness and distress. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - December 20, 2023 Category: Psychiatry Source Type: research

Newborn Brain Function and Early Emerging Callous-Unemotional Traits
This cohort study uses mother-infant dyads to investigate whether alterations in newborn brain function precede the development of callous-unemotional traits and are associated with later symptom severity. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - December 20, 2023 Category: Psychiatry Source Type: research

Pharmacologic Treatment of Schizophrenia Beyond Dopamine Receptor Blockade
This Viewpoint describes the need for novel mechanism of action agents for schizophrenia to extend therapeutic options and improve outcomes. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - December 13, 2023 Category: Psychiatry Source Type: research

All-Cause and Cause-Specific Mortality Among Individuals With Hypochondriasis
This Swedish nationwide cohort study investigates all-cause and cause-specific mortality among a large cohort of individuals with hypochondriasis and a demographically matched cohort of individuals without hypochondriasis. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - December 13, 2023 Category: Psychiatry Source Type: research

Mindfulness-Oriented Recovery Enhancement vs Usual Care in Opioid Use Disorder
This randomized clinical trial investigates the relative efficacy of Mindfulness-Oriented Recovery Enhancement in addition to methadone treatment as usual compared with usual care only. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - December 7, 2023 Category: Psychiatry Source Type: research