International Journal of Hematology 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Multicenter evaluation of the addition of eltrombopag to immunosuppressive therapy for adults with severe aplastic anemia
Int J Hematol. 2023 Oct 26. doi: 10.1007/s12185-023-03670-3. Online ahead of print.ABSTRACTEltrombopag has been shown to improve response rates when added to standard therapy in adults with severe aplastic anemia in controlled trial settings. However, outcomes in real-world populations have mostly been examined in small retrospective studies. This robust, multicenter, retrospective cohort study across six academic health systems compared outcomes in patients who received immunosuppressive therapy with or without eltrombopag. The study included 82 patients who received front-line therapy from January 2014 to August 2021. Ov...
Source: International Journal of Hematology - October 26, 2023 Category: Hematology Authors: Lauren T Shinn Lydia L Benitez Anthony J Perissinotti Justin H Reid Kaitlyn M Buhlinger Hendrik van Deventer Dylan Barth Charlotte B Wagner Kyle Zacholski Ruchi Desai Ashley Soule Sarah E Stump Taylor M Weis Dale Bixby Patrick Burke Kristen Pettit Bernard Source Type: research
Multicenter evaluation of the addition of eltrombopag to immunosuppressive therapy for adults with severe aplastic anemia
Int J Hematol. 2023 Oct 26. doi: 10.1007/s12185-023-03670-3. Online ahead of print.ABSTRACTEltrombopag has been shown to improve response rates when added to standard therapy in adults with severe aplastic anemia in controlled trial settings. However, outcomes in real-world populations have mostly been examined in small retrospective studies. This robust, multicenter, retrospective cohort study across six academic health systems compared outcomes in patients who received immunosuppressive therapy with or without eltrombopag. The study included 82 patients who received front-line therapy from January 2014 to August 2021. Ov...
Source: International Journal of Hematology - October 26, 2023 Category: Hematology Authors: Lauren T Shinn Lydia L Benitez Anthony J Perissinotti Justin H Reid Kaitlyn M Buhlinger Hendrik van Deventer Dylan Barth Charlotte B Wagner Kyle Zacholski Ruchi Desai Ashley Soule Sarah E Stump Taylor M Weis Dale Bixby Patrick Burke Kristen Pettit Bernard Source Type: research
Multicenter evaluation of the addition of eltrombopag to immunosuppressive therapy for adults with severe aplastic anemia
Int J Hematol. 2023 Oct 26. doi: 10.1007/s12185-023-03670-3. Online ahead of print.ABSTRACTEltrombopag has been shown to improve response rates when added to standard therapy in adults with severe aplastic anemia in controlled trial settings. However, outcomes in real-world populations have mostly been examined in small retrospective studies. This robust, multicenter, retrospective cohort study across six academic health systems compared outcomes in patients who received immunosuppressive therapy with or without eltrombopag. The study included 82 patients who received front-line therapy from January 2014 to August 2021. Ov...
Source: International Journal of Hematology - October 26, 2023 Category: Hematology Authors: Lauren T Shinn Lydia L Benitez Anthony J Perissinotti Justin H Reid Kaitlyn M Buhlinger Hendrik van Deventer Dylan Barth Charlotte B Wagner Kyle Zacholski Ruchi Desai Ashley Soule Sarah E Stump Taylor M Weis Dale Bixby Patrick Burke Kristen Pettit Bernard Source Type: research
Multicenter evaluation of the addition of eltrombopag to immunosuppressive therapy for adults with severe aplastic anemia
Int J Hematol. 2023 Oct 26. doi: 10.1007/s12185-023-03670-3. Online ahead of print.ABSTRACTEltrombopag has been shown to improve response rates when added to standard therapy in adults with severe aplastic anemia in controlled trial settings. However, outcomes in real-world populations have mostly been examined in small retrospective studies. This robust, multicenter, retrospective cohort study across six academic health systems compared outcomes in patients who received immunosuppressive therapy with or without eltrombopag. The study included 82 patients who received front-line therapy from January 2014 to August 2021. Ov...
Source: International Journal of Hematology - October 26, 2023 Category: Hematology Authors: Lauren T Shinn Lydia L Benitez Anthony J Perissinotti Justin H Reid Kaitlyn M Buhlinger Hendrik van Deventer Dylan Barth Charlotte B Wagner Kyle Zacholski Ruchi Desai Ashley Soule Sarah E Stump Taylor M Weis Dale Bixby Patrick Burke Kristen Pettit Bernard Source Type: research
Multicenter evaluation of the addition of eltrombopag to immunosuppressive therapy for adults with severe aplastic anemia
Int J Hematol. 2023 Oct 26. doi: 10.1007/s12185-023-03670-3. Online ahead of print.ABSTRACTEltrombopag has been shown to improve response rates when added to standard therapy in adults with severe aplastic anemia in controlled trial settings. However, outcomes in real-world populations have mostly been examined in small retrospective studies. This robust, multicenter, retrospective cohort study across six academic health systems compared outcomes in patients who received immunosuppressive therapy with or without eltrombopag. The study included 82 patients who received front-line therapy from January 2014 to August 2021. Ov...
Source: International Journal of Hematology - October 26, 2023 Category: Hematology Authors: Lauren T Shinn Lydia L Benitez Anthony J Perissinotti Justin H Reid Kaitlyn M Buhlinger Hendrik van Deventer Dylan Barth Charlotte B Wagner Kyle Zacholski Ruchi Desai Ashley Soule Sarah E Stump Taylor M Weis Dale Bixby Patrick Burke Kristen Pettit Bernard Source Type: research
Multicenter evaluation of the addition of eltrombopag to immunosuppressive therapy for adults with severe aplastic anemia
Int J Hematol. 2023 Oct 26. doi: 10.1007/s12185-023-03670-3. Online ahead of print.ABSTRACTEltrombopag has been shown to improve response rates when added to standard therapy in adults with severe aplastic anemia in controlled trial settings. However, outcomes in real-world populations have mostly been examined in small retrospective studies. This robust, multicenter, retrospective cohort study across six academic health systems compared outcomes in patients who received immunosuppressive therapy with or without eltrombopag. The study included 82 patients who received front-line therapy from January 2014 to August 2021. Ov...
Source: International Journal of Hematology - October 26, 2023 Category: Hematology Authors: Lauren T Shinn Lydia L Benitez Anthony J Perissinotti Justin H Reid Kaitlyn M Buhlinger Hendrik van Deventer Dylan Barth Charlotte B Wagner Kyle Zacholski Ruchi Desai Ashley Soule Sarah E Stump Taylor M Weis Dale Bixby Patrick Burke Kristen Pettit Bernard Source Type: research
Multicenter evaluation of the addition of eltrombopag to immunosuppressive therapy for adults with severe aplastic anemia
Int J Hematol. 2023 Oct 26. doi: 10.1007/s12185-023-03670-3. Online ahead of print.ABSTRACTEltrombopag has been shown to improve response rates when added to standard therapy in adults with severe aplastic anemia in controlled trial settings. However, outcomes in real-world populations have mostly been examined in small retrospective studies. This robust, multicenter, retrospective cohort study across six academic health systems compared outcomes in patients who received immunosuppressive therapy with or without eltrombopag. The study included 82 patients who received front-line therapy from January 2014 to August 2021. Ov...
Source: International Journal of Hematology - October 26, 2023 Category: Hematology Authors: Lauren T Shinn Lydia L Benitez Anthony J Perissinotti Justin H Reid Kaitlyn M Buhlinger Hendrik van Deventer Dylan Barth Charlotte B Wagner Kyle Zacholski Ruchi Desai Ashley Soule Sarah E Stump Taylor M Weis Dale Bixby Patrick Burke Kristen Pettit Bernard Source Type: research
Multicenter evaluation of the addition of eltrombopag to immunosuppressive therapy for adults with severe aplastic anemia
Int J Hematol. 2023 Oct 26. doi: 10.1007/s12185-023-03670-3. Online ahead of print.ABSTRACTEltrombopag has been shown to improve response rates when added to standard therapy in adults with severe aplastic anemia in controlled trial settings. However, outcomes in real-world populations have mostly been examined in small retrospective studies. This robust, multicenter, retrospective cohort study across six academic health systems compared outcomes in patients who received immunosuppressive therapy with or without eltrombopag. The study included 82 patients who received front-line therapy from January 2014 to August 2021. Ov...
Source: International Journal of Hematology - October 26, 2023 Category: Hematology Authors: Lauren T Shinn Lydia L Benitez Anthony J Perissinotti Justin H Reid Kaitlyn M Buhlinger Hendrik van Deventer Dylan Barth Charlotte B Wagner Kyle Zacholski Ruchi Desai Ashley Soule Sarah E Stump Taylor M Weis Dale Bixby Patrick Burke Kristen Pettit Bernard Source Type: research
Clinical implications of augmented renal clearance after unrelated single cord blood transplantation in adults
Int J Hematol. 2023 Oct 18. doi: 10.1007/s12185-023-03669-w. Online ahead of print.ABSTRACTAugmented renal clearance (ARC) is a phenomenon characterized by increased renal functionality, which can impact the pharmacokinetics and pharmacodynamics of antimicrobial drugs eliminated by the kidneys. It is a potential concern for infection treatment. Cord blood transplantation (CBT) is primarily impeded by delayed neutrophil recovery and immune reconstitution, thereby increasing susceptibility to infection. However, the clinical implications of ARC following CBT remain unexplored. We retrospectively assessed the influence of ARC...
Source: International Journal of Hematology - October 18, 2023 Category: Hematology Authors: Takaaki Konuma Kosuke Takano Maki Monna-Oiwa Masamichi Isobe Seiko Kato Satoshi Takahashi Yasuhito Nannya Source Type: research
Clinical implications of augmented renal clearance after unrelated single cord blood transplantation in adults
Int J Hematol. 2023 Oct 18. doi: 10.1007/s12185-023-03669-w. Online ahead of print.ABSTRACTAugmented renal clearance (ARC) is a phenomenon characterized by increased renal functionality, which can impact the pharmacokinetics and pharmacodynamics of antimicrobial drugs eliminated by the kidneys. It is a potential concern for infection treatment. Cord blood transplantation (CBT) is primarily impeded by delayed neutrophil recovery and immune reconstitution, thereby increasing susceptibility to infection. However, the clinical implications of ARC following CBT remain unexplored. We retrospectively assessed the influence of ARC...
Source: International Journal of Hematology - October 18, 2023 Category: Hematology Authors: Takaaki Konuma Kosuke Takano Maki Monna-Oiwa Masamichi Isobe Seiko Kato Satoshi Takahashi Yasuhito Nannya Source Type: research
Clinical implications of augmented renal clearance after unrelated single cord blood transplantation in adults
Int J Hematol. 2023 Oct 18. doi: 10.1007/s12185-023-03669-w. Online ahead of print.ABSTRACTAugmented renal clearance (ARC) is a phenomenon characterized by increased renal functionality, which can impact the pharmacokinetics and pharmacodynamics of antimicrobial drugs eliminated by the kidneys. It is a potential concern for infection treatment. Cord blood transplantation (CBT) is primarily impeded by delayed neutrophil recovery and immune reconstitution, thereby increasing susceptibility to infection. However, the clinical implications of ARC following CBT remain unexplored. We retrospectively assessed the influence of ARC...
Source: International Journal of Hematology - October 18, 2023 Category: Hematology Authors: Takaaki Konuma Kosuke Takano Maki Monna-Oiwa Masamichi Isobe Seiko Kato Satoshi Takahashi Yasuhito Nannya Source Type: research
Clinical implications of augmented renal clearance after unrelated single cord blood transplantation in adults
Int J Hematol. 2023 Oct 18. doi: 10.1007/s12185-023-03669-w. Online ahead of print.ABSTRACTAugmented renal clearance (ARC) is a phenomenon characterized by increased renal functionality, which can impact the pharmacokinetics and pharmacodynamics of antimicrobial drugs eliminated by the kidneys. It is a potential concern for infection treatment. Cord blood transplantation (CBT) is primarily impeded by delayed neutrophil recovery and immune reconstitution, thereby increasing susceptibility to infection. However, the clinical implications of ARC following CBT remain unexplored. We retrospectively assessed the influence of ARC...
Source: International Journal of Hematology - October 18, 2023 Category: Hematology Authors: Takaaki Konuma Kosuke Takano Maki Monna-Oiwa Masamichi Isobe Seiko Kato Satoshi Takahashi Yasuhito Nannya Source Type: research
Clinical implications of augmented renal clearance after unrelated single cord blood transplantation in adults
Int J Hematol. 2023 Oct 18. doi: 10.1007/s12185-023-03669-w. Online ahead of print.ABSTRACTAugmented renal clearance (ARC) is a phenomenon characterized by increased renal functionality, which can impact the pharmacokinetics and pharmacodynamics of antimicrobial drugs eliminated by the kidneys. It is a potential concern for infection treatment. Cord blood transplantation (CBT) is primarily impeded by delayed neutrophil recovery and immune reconstitution, thereby increasing susceptibility to infection. However, the clinical implications of ARC following CBT remain unexplored. We retrospectively assessed the influence of ARC...
Source: International Journal of Hematology - October 18, 2023 Category: Hematology Authors: Takaaki Konuma Kosuke Takano Maki Monna-Oiwa Masamichi Isobe Seiko Kato Satoshi Takahashi Yasuhito Nannya Source Type: research
Clinical implications of augmented renal clearance after unrelated single cord blood transplantation in adults
Int J Hematol. 2023 Oct 18. doi: 10.1007/s12185-023-03669-w. Online ahead of print.ABSTRACTAugmented renal clearance (ARC) is a phenomenon characterized by increased renal functionality, which can impact the pharmacokinetics and pharmacodynamics of antimicrobial drugs eliminated by the kidneys. It is a potential concern for infection treatment. Cord blood transplantation (CBT) is primarily impeded by delayed neutrophil recovery and immune reconstitution, thereby increasing susceptibility to infection. However, the clinical implications of ARC following CBT remain unexplored. We retrospectively assessed the influence of ARC...
Source: International Journal of Hematology - October 18, 2023 Category: Hematology Authors: Takaaki Konuma Kosuke Takano Maki Monna-Oiwa Masamichi Isobe Seiko Kato Satoshi Takahashi Yasuhito Nannya Source Type: research
Clinical implications of augmented renal clearance after unrelated single cord blood transplantation in adults
Int J Hematol. 2023 Oct 18. doi: 10.1007/s12185-023-03669-w. Online ahead of print.ABSTRACTAugmented renal clearance (ARC) is a phenomenon characterized by increased renal functionality, which can impact the pharmacokinetics and pharmacodynamics of antimicrobial drugs eliminated by the kidneys. It is a potential concern for infection treatment. Cord blood transplantation (CBT) is primarily impeded by delayed neutrophil recovery and immune reconstitution, thereby increasing susceptibility to infection. However, the clinical implications of ARC following CBT remain unexplored. We retrospectively assessed the influence of ARC...
Source: International Journal of Hematology - October 18, 2023 Category: Hematology Authors: Takaaki Konuma Kosuke Takano Maki Monna-Oiwa Masamichi Isobe Seiko Kato Satoshi Takahashi Yasuhito Nannya Source Type: research
