NFIL3 aggravates human coronary artery endothelial cell injury by promoting ITGAM transcription in Kawasaki disease
CONCLUSION: NFIL3 aggravated KD serum-induced HCAEC injury by promoting ITGAM transcription, which provided new insights into the treatment of KD.PMID:37933872 | DOI:10.1080/16078454.2023.2277502 (Source: Hematology)
Source: Hematology - November 7, 2023 Category: Hematology Authors: Li Chen Zhiyang Shangguan Zeya Dong Qunfan Deng Yunyun Ding Shulong Yang Source Type: research
Cost-effectiveness analysis of low-dose prophylaxis versus on-demand treatment for moderate-to-severe hemophilia A in India
CONCLUSION: Using intermediate-dose prophylactic factor VIII therapy is a cost-effective approach that improves clinical outcomes compared to on-demand therapy in the Indian adult and pediatric HA populations without inhibitors.PMID:37933875 | DOI:10.1080/16078454.2023.2277497 (Source: Hematology)
Source: Hematology - November 7, 2023 Category: Hematology Authors: Tulika Seth Kapil Garg Prakas Kumar Mandal Anupam Datta Shailendra Verma Suresh Hanagavadi Usha Rani Thota Source Type: research
NFIL3 aggravates human coronary artery endothelial cell injury by promoting ITGAM transcription in Kawasaki disease
CONCLUSION: NFIL3 aggravated KD serum-induced HCAEC injury by promoting ITGAM transcription, which provided new insights into the treatment of KD.PMID:37933872 | DOI:10.1080/16078454.2023.2277502 (Source: Hematology)
Source: Hematology - November 7, 2023 Category: Hematology Authors: Li Chen Zhiyang Shangguan Zeya Dong Qunfan Deng Yunyun Ding Shulong Yang Source Type: research
Cost-effectiveness analysis of low-dose prophylaxis versus on-demand treatment for moderate-to-severe hemophilia A in India
CONCLUSION: Using intermediate-dose prophylactic factor VIII therapy is a cost-effective approach that improves clinical outcomes compared to on-demand therapy in the Indian adult and pediatric HA populations without inhibitors.PMID:37933875 | DOI:10.1080/16078454.2023.2277497 (Source: Hematology)
Source: Hematology - November 7, 2023 Category: Hematology Authors: Tulika Seth Kapil Garg Prakas Kumar Mandal Anupam Datta Shailendra Verma Suresh Hanagavadi Usha Rani Thota Source Type: research
Intestinal flora altered and correlated with interleukin-2/4 in patients with primary immune thrombocytopenia
CONCLUSION: The mechanism underlying functional and structural changes of intestinal flora in ITP patients may be related to inflammation and immunity, providing possibilities of probiotics or fecal transplants for ITP.PMID:37921501 | DOI:10.1080/16078454.2023.2277501 (Source: Hematology)
Source: Hematology - November 3, 2023 Category: Hematology Authors: Honghui Wang Hui Bi Muran Yang Xiuli Wang Chuanju Song Wen Yang Yacan Wang Dongmei Xie Huiting Li Zeping Zhou Source Type: research
Maintenance therapy with a combination of azacitidine, danazol, and thalidomide after intensive chemotherapy in patients with acute myeloid leukemia
CONCLUSION: AZA combined with DNZ and THD maintenance therapy is effective for patients with AML who are ineligible for allogeneic hematopoietic stem cell transplantation. Further studies with large sample sizes and randomized are needed to verify these findings.PMID:37916643 | DOI:10.1080/16078454.2023.2276550 (Source: Hematology)
Source: Hematology - November 2, 2023 Category: Hematology Authors: Fang Zheng Qianqian Li Sisi Yang Zhen Zhou Qingfan Zeng Kaiqi Liu Source Type: research
Sigma metric used to evaluate the performance of haematology analysers: choosing an internal reference analyser for the laboratory
CONCLUSION: The sigma metric can be used as a guide to choose the QC strategy and plan QC frequency. It can facilitate the comparison of the same assay performed by multiple systems.PMID:37916652 | DOI:10.1080/16078454.2023.2277498 (Source: Hematology)
Source: Hematology - November 2, 2023 Category: Hematology Authors: Min Li Xiaojuan Li Xiaohong Lu Mingqin Zhong Lin Wang Mingze Song Feng Xue Source Type: research
Maintenance therapy with a combination of azacitidine, danazol, and thalidomide after intensive chemotherapy in patients with acute myeloid leukemia
CONCLUSION: AZA combined with DNZ and THD maintenance therapy is effective for patients with AML who are ineligible for allogeneic hematopoietic stem cell transplantation. Further studies with large sample sizes and randomized are needed to verify these findings.PMID:37916643 | DOI:10.1080/16078454.2023.2276550 (Source: Hematology)
Source: Hematology - November 2, 2023 Category: Hematology Authors: Fang Zheng Qianqian Li Sisi Yang Zhen Zhou Qingfan Zeng Kaiqi Liu Source Type: research
Sigma metric used to evaluate the performance of haematology analysers: choosing an internal reference analyser for the laboratory
CONCLUSION: The sigma metric can be used as a guide to choose the QC strategy and plan QC frequency. It can facilitate the comparison of the same assay performed by multiple systems.PMID:37916652 | DOI:10.1080/16078454.2023.2277498 (Source: Hematology)
Source: Hematology - November 2, 2023 Category: Hematology Authors: Min Li Xiaojuan Li Xiaohong Lu Mingqin Zhong Lin Wang Mingze Song Feng Xue Source Type: research
The efficacy and adverse events of arsenic trioxide for the patients with myelodysplastic syndrome: a systematic review and component network meta-analysis
CONCLUSION: ATO may be an effective and well-tolerant option for patients with myelodysplastic syndrome.PMID:37908176 | DOI:10.1080/16078454.2023.2274149 (Source: Hematology)
Source: Hematology - November 1, 2023 Category: Hematology Authors: Xiaohua Huang Yuan Liu Ruixuan Liu Xiaoqiu Zou Hongyong Yang Source Type: research
Autologous followed by allogeneic versus tandem-autologous transplantation in high-risk, newly diagnosed multiple myeloma: a systematic review and meta-analysis
CONCLUSION: Auto-allo-SCT seemed to be associated with improvements in PFS and CR when compared to tandem-auto-SCT in patients with HRMM, but it did not lead to a significant improvement in OS. Furthermore, patients in the auto-allo-SCT group were at a higher risk of developing TRM and NRM. Auto-allo-SCT transplantation should not be routinely incorporated into HRMM therapy but rather should be considered investigational.PMID:37850613 | DOI:10.1080/16078454.2023.2269509 (Source: Hematology)
Source: Hematology - October 18, 2023 Category: Hematology Authors: Min Wei Chunhong Xie Jinxiong Huang Qin Liu Yongrong Lai Source Type: research
