Neuroestradiol and neuronal development: Not an exclusive male tale anymore
Front Neuroendocrinol. 2023 Sep 7;71:101102. doi: 10.1016/j.yfrne.2023.101102. Online ahead of print.ABSTRACTThe brain synthesizes a variety of neurosteroids, including neuroestradiol. Inhibition of neuroestradiol synthesis results in alterations in basic neurodevelopmental processes, such as neurogenesis, neuroblast migration, neuritogenesis and synaptogenesis. Although the neurodevelopmental actions of neuroestradiol are exerted in both sexes, some of them are sex-specific, such as the well characterized effects of neuroestradiol derived from the metabolism of testicular testosterone during critical periods of male brain...
Source: Frontiers in Neuroendocrinology - September 9, 2023 Category: Endocrinology Authors: Luis M Garcia-Segura Pablo M éndez M Angeles Arevalo I ñigo Azcoitia Source Type: research
Neuroestradiol and neuronal development: Not an exclusive male tale anymore
Front Neuroendocrinol. 2023 Sep 7;71:101102. doi: 10.1016/j.yfrne.2023.101102. Online ahead of print.ABSTRACTThe brain synthesizes a variety of neurosteroids, including neuroestradiol. Inhibition of neuroestradiol synthesis results in alterations in basic neurodevelopmental processes, such as neurogenesis, neuroblast migration, neuritogenesis and synaptogenesis. Although the neurodevelopmental actions of neuroestradiol are exerted in both sexes, some of them are sex-specific, such as the well characterized effects of neuroestradiol derived from the metabolism of testicular testosterone during critical periods of male brain...
Source: Frontiers in Neuroendocrinology - September 9, 2023 Category: Endocrinology Authors: Luis M Garcia-Segura Pablo M éndez M Angeles Arevalo I ñigo Azcoitia Source Type: research
Neuroestradiol and neuronal development: Not an exclusive male tale anymore
Front Neuroendocrinol. 2023 Sep 7;71:101102. doi: 10.1016/j.yfrne.2023.101102. Online ahead of print.ABSTRACTThe brain synthesizes a variety of neurosteroids, including neuroestradiol. Inhibition of neuroestradiol synthesis results in alterations in basic neurodevelopmental processes, such as neurogenesis, neuroblast migration, neuritogenesis and synaptogenesis. Although the neurodevelopmental actions of neuroestradiol are exerted in both sexes, some of them are sex-specific, such as the well characterized effects of neuroestradiol derived from the metabolism of testicular testosterone during critical periods of male brain...
Source: Frontiers in Neuroendocrinology - September 9, 2023 Category: Endocrinology Authors: Luis M Garcia-Segura Pablo M éndez M Angeles Arevalo I ñigo Azcoitia Source Type: research
Neuroestradiol and neuronal development: Not an exclusive male tale anymore
Front Neuroendocrinol. 2023 Sep 7;71:101102. doi: 10.1016/j.yfrne.2023.101102. Online ahead of print.ABSTRACTThe brain synthesizes a variety of neurosteroids, including neuroestradiol. Inhibition of neuroestradiol synthesis results in alterations in basic neurodevelopmental processes, such as neurogenesis, neuroblast migration, neuritogenesis and synaptogenesis. Although the neurodevelopmental actions of neuroestradiol are exerted in both sexes, some of them are sex-specific, such as the well characterized effects of neuroestradiol derived from the metabolism of testicular testosterone during critical periods of male brain...
Source: Frontiers in Neuroendocrinology - September 9, 2023 Category: Endocrinology Authors: Luis M Garcia-Segura Pablo M éndez M Angeles Arevalo I ñigo Azcoitia Source Type: research
Neuroestradiol and neuronal development: Not an exclusive male tale anymore
Front Neuroendocrinol. 2023 Sep 7;71:101102. doi: 10.1016/j.yfrne.2023.101102. Online ahead of print.ABSTRACTThe brain synthesizes a variety of neurosteroids, including neuroestradiol. Inhibition of neuroestradiol synthesis results in alterations in basic neurodevelopmental processes, such as neurogenesis, neuroblast migration, neuritogenesis and synaptogenesis. Although the neurodevelopmental actions of neuroestradiol are exerted in both sexes, some of them are sex-specific, such as the well characterized effects of neuroestradiol derived from the metabolism of testicular testosterone during critical periods of male brain...
Source: Frontiers in Neuroendocrinology - September 9, 2023 Category: Endocrinology Authors: Luis M Garcia-Segura Pablo M éndez M Angeles Arevalo I ñigo Azcoitia Source Type: research
Neuroestradiol and neuronal development: Not an exclusive male tale anymore
Front Neuroendocrinol. 2023 Sep 7;71:101102. doi: 10.1016/j.yfrne.2023.101102. Online ahead of print.ABSTRACTThe brain synthesizes a variety of neurosteroids, including neuroestradiol. Inhibition of neuroestradiol synthesis results in alterations in basic neurodevelopmental processes, such as neurogenesis, neuroblast migration, neuritogenesis and synaptogenesis. Although the neurodevelopmental actions of neuroestradiol are exerted in both sexes, some of them are sex-specific, such as the well characterized effects of neuroestradiol derived from the metabolism of testicular testosterone during critical periods of male brain...
Source: Frontiers in Neuroendocrinology - September 9, 2023 Category: Endocrinology Authors: Luis M Garcia-Segura Pablo M éndez M Angeles Arevalo I ñigo Azcoitia Source Type: research
Neuroestradiol and neuronal development: Not an exclusive male tale anymore
Front Neuroendocrinol. 2023 Sep 7;71:101102. doi: 10.1016/j.yfrne.2023.101102. Online ahead of print.ABSTRACTThe brain synthesizes a variety of neurosteroids, including neuroestradiol. Inhibition of neuroestradiol synthesis results in alterations in basic neurodevelopmental processes, such as neurogenesis, neuroblast migration, neuritogenesis and synaptogenesis. Although the neurodevelopmental actions of neuroestradiol are exerted in both sexes, some of them are sex-specific, such as the well characterized effects of neuroestradiol derived from the metabolism of testicular testosterone during critical periods of male brain...
Source: Frontiers in Neuroendocrinology - September 9, 2023 Category: Endocrinology Authors: Luis M Garcia-Segura Pablo M éndez M Angeles Arevalo I ñigo Azcoitia Source Type: research
Neuroestradiol and neuronal development: Not an exclusive male tale anymore
Front Neuroendocrinol. 2023 Sep 7;71:101102. doi: 10.1016/j.yfrne.2023.101102. Online ahead of print.ABSTRACTThe brain synthesizes a variety of neurosteroids, including neuroestradiol. Inhibition of neuroestradiol synthesis results in alterations in basic neurodevelopmental processes, such as neurogenesis, neuroblast migration, neuritogenesis and synaptogenesis. Although the neurodevelopmental actions of neuroestradiol are exerted in both sexes, some of them are sex-specific, such as the well characterized effects of neuroestradiol derived from the metabolism of testicular testosterone during critical periods of male brain...
Source: Frontiers in Neuroendocrinology - September 9, 2023 Category: Endocrinology Authors: Luis M Garcia-Segura Pablo M éndez M Angeles Arevalo I ñigo Azcoitia Source Type: research
Neuroestradiol and neuronal development: Not an exclusive male tale anymore
Front Neuroendocrinol. 2023 Sep 7;71:101102. doi: 10.1016/j.yfrne.2023.101102. Online ahead of print.ABSTRACTThe brain synthesizes a variety of neurosteroids, including neuroestradiol. Inhibition of neuroestradiol synthesis results in alterations in basic neurodevelopmental processes, such as neurogenesis, neuroblast migration, neuritogenesis and synaptogenesis. Although the neurodevelopmental actions of neuroestradiol are exerted in both sexes, some of them are sex-specific, such as the well characterized effects of neuroestradiol derived from the metabolism of testicular testosterone during critical periods of male brain...
Source: Frontiers in Neuroendocrinology - September 9, 2023 Category: Endocrinology Authors: Luis M Garcia-Segura Pablo M éndez M Angeles Arevalo I ñigo Azcoitia Source Type: research
Neuroestradiol and neuronal development: not an exclusive male tale anymore
Front Neuroendocrinol. 2023 Sep 7:101102. doi: 10.1016/j.yfrne.2023.101102. Online ahead of print.ABSTRACTThe brain synthesizes a variety of neurosteroids, including neuroestradiol. Inhibition of neuroestradiol synthesis results in alterations in basic neurodevelopmental processes, such as neurogenesis, neuroblast migration, neuritogenesis and synaptogenesis. Although the neurodevelopmental actions of neuroestradiol are exerted in both sexes, some of them are sex-specific, such as the well characterized effects of neuroestradiol derived from the metabolism of testicular testosterone during critical periods of male brain de...
Source: Frontiers in Neuroendocrinology - September 9, 2023 Category: Endocrinology Authors: Luis M Garcia-Segura Pablo M éndez M Angeles Arevalo I ñigo Azcoitia Source Type: research
Neuroestradiol and neuronal development: not an exclusive male tale anymore
Front Neuroendocrinol. 2023 Sep 7:101102. doi: 10.1016/j.yfrne.2023.101102. Online ahead of print.ABSTRACTThe brain synthesizes a variety of neurosteroids, including neuroestradiol. Inhibition of neuroestradiol synthesis results in alterations in basic neurodevelopmental processes, such as neurogenesis, neuroblast migration, neuritogenesis and synaptogenesis. Although the neurodevelopmental actions of neuroestradiol are exerted in both sexes, some of them are sex-specific, such as the well characterized effects of neuroestradiol derived from the metabolism of testicular testosterone during critical periods of male brain de...
Source: Frontiers in Neuroendocrinology - September 9, 2023 Category: Endocrinology Authors: Luis M Garcia-Segura Pablo M éndez M Angeles Arevalo I ñigo Azcoitia Source Type: research
Neuroestradiol and neuronal development: not an exclusive male tale anymore
Front Neuroendocrinol. 2023 Sep 7:101102. doi: 10.1016/j.yfrne.2023.101102. Online ahead of print.ABSTRACTThe brain synthesizes a variety of neurosteroids, including neuroestradiol. Inhibition of neuroestradiol synthesis results in alterations in basic neurodevelopmental processes, such as neurogenesis, neuroblast migration, neuritogenesis and synaptogenesis. Although the neurodevelopmental actions of neuroestradiol are exerted in both sexes, some of them are sex-specific, such as the well characterized effects of neuroestradiol derived from the metabolism of testicular testosterone during critical periods of male brain de...
Source: Frontiers in Neuroendocrinology - September 9, 2023 Category: Endocrinology Authors: Luis M Garcia-Segura Pablo M éndez M Angeles Arevalo I ñigo Azcoitia Source Type: research
Neuroestradiol and neuronal development: not an exclusive male tale anymore
Front Neuroendocrinol. 2023 Sep 7:101102. doi: 10.1016/j.yfrne.2023.101102. Online ahead of print.ABSTRACTThe brain synthesizes a variety of neurosteroids, including neuroestradiol. Inhibition of neuroestradiol synthesis results in alterations in basic neurodevelopmental processes, such as neurogenesis, neuroblast migration, neuritogenesis and synaptogenesis. Although the neurodevelopmental actions of neuroestradiol are exerted in both sexes, some of them are sex-specific, such as the well characterized effects of neuroestradiol derived from the metabolism of testicular testosterone during critical periods of male brain de...
Source: Frontiers in Neuroendocrinology - September 9, 2023 Category: Endocrinology Authors: Luis M Garcia-Segura Pablo M éndez M Angeles Arevalo I ñigo Azcoitia Source Type: research
Androgen Action on Myogenesis Throughout the Lifespan; Comparison with Neurogenesis
Front Neuroendocrinol. 2023 Sep 3:101101. doi: 10.1016/j.yfrne.2023.101101. Online ahead of print.ABSTRACTAndrogens' pleiotropic actions in promoting sex differences present not only a challenge to providing a comprehensive account of their function, but also an opportunity to gain insights by comparing androgenic actions across organ systems. Although often overlooked by neuroscientists, skeletal muscle is another androgen-responsive organ system which shares with the nervous system properties of electrochemical excitability, behavioral relevance, and remarkable capacity for adaptive plasticity. Here we review androgenic ...
Source: Frontiers in Neuroendocrinology - September 5, 2023 Category: Endocrinology Authors: Sabrina Tzivia Barsky Douglas Ashley Monks Source Type: research
Androgen Action on Myogenesis Throughout the Lifespan; Comparison with Neurogenesis
Front Neuroendocrinol. 2023 Sep 3:101101. doi: 10.1016/j.yfrne.2023.101101. Online ahead of print.ABSTRACTAndrogens' pleiotropic actions in promoting sex differences present not only a challenge to providing a comprehensive account of their function, but also an opportunity to gain insights by comparing androgenic actions across organ systems. Although often overlooked by neuroscientists, skeletal muscle is another androgen-responsive organ system which shares with the nervous system properties of electrochemical excitability, behavioral relevance, and remarkable capacity for adaptive plasticity. Here we review androgenic ...
Source: Frontiers in Neuroendocrinology - September 5, 2023 Category: Endocrinology Authors: Sabrina Tzivia Barsky Douglas Ashley Monks Source Type: research
