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Comparative efficacy of systemic treatments for atopic dermatitis in adults
Expert Rev Clin Immunol. 2023 Dec 1. doi: 10.1080/1744666X.2023.2291038. Online ahead of print.ABSTRACTINTRODUCTION: Atopic dermatitis is a prevalent skin condition causing dry, pruritic, inflammatory skin lesions that can result in patient distress. Various emerging classes of therapy, including biologics and Janus kinase inhibitors, have been developed in recent years.AREAS COVERED: A literature search of PubMed was conducted to explore existing literature and clinical trials. Treatment options and adverse effects were summarized by class and severity. JAK inhibitors and biologics are efficacious options for adults with ...
Source: Expert Review of Clinical Immunology - December 1, 2023 Category: Allergy & Immunology Authors: Jenna Sesi Steven R Feldman Source Type: research

How should we approach management of childhood onset chronic anterior uveitis refractory to adalimumab?
Expert Rev Clin Immunol. 2023 Nov 21:1-10. doi: 10.1080/1744666X.2023.2284845. Online ahead of print.ABSTRACTINTRODUCTION: The management of refractory juvenile idiopathic associated uveitis (JIAU) or childhood-onset chronic anterior uveitis (CAU) is a challenge. There is no clear consensus or evidence base for to suggest the most appropriate therapy after primary or secondary failure of biweekly adalimumab. In this scenario, most clinicians advocate switching to another anti-tumor necrosis factor alpha inhibitor; however, there are a variety of other disease modifying agents to choose from albeit with a differing levels o...
Source: Expert Review of Clinical Immunology - November 22, 2023 Category: Allergy & Immunology Authors: Ivan Foeldvari Harry Petrushkin Source Type: research

How should we approach management of childhood onset chronic anterior uveitis refractory to adalimumab?
Expert Rev Clin Immunol. 2023 Nov 21. doi: 10.1080/1744666X.2023.2284845. Online ahead of print.ABSTRACTINTRODUCTION: The management of refractory juvenile idiopathic associated uveitis (JIAU) or childhood-onset chronic anterior uveitis (CAU) is a challenge. There is no clear consensus or evidence base for to suggest the most appropriate therapy after primary or secondary failure of biweekly adalimumab. In this scenario, most clinicians advocate switching to another anti-tumor necrosis factor alpha inhibitor, however, there are a variety of other disease modifying agents to choose from albeit with a differing levels of evi...
Source: Expert Review of Clinical Immunology - November 22, 2023 Category: Allergy & Immunology Authors: Ivan Foeldvari Harry Petrushkin Source Type: research

How does sleep influence asthma through immunity?
Expert Rev Clin Immunol. 2023 Nov 14:1-4. doi: 10.1080/1744666X.2023.2284213. Online ahead of print.NO ABSTRACTPMID:37962951 | DOI:10.1080/1744666X.2023.2284213 (Source: Expert Review of Clinical Immunology)
Source: Expert Review of Clinical Immunology - November 14, 2023 Category: Allergy & Immunology Authors: Ahmad Z Al Meslamani Source Type: research

Factors that influence infliximab biosimilar trough levels in the pediatric inflammatory bowel disease population
CONCLUSIONS: This study discovered some predictors for IFX-BioS TLs in IBD children. Knowledge of predictive factors could help physicians choose the best dosing regimen.PMID:37962991 | DOI:10.1080/1744666X.2023.2284226 (Source: Expert Review of Clinical Immunology)
Source: Expert Review of Clinical Immunology - November 14, 2023 Category: Allergy & Immunology Authors: Valeria Dipasquale Angela Alibrandi Salvatore Pellegrino Vincenzo Ramistella Claudio Romano Source Type: research