Insights into the immunological links between dietary habits and asthma
Expert Rev Clin Immunol. 2023 Oct 28. doi: 10.1080/1744666X.2023.2277864. Online ahead of print.NO ABSTRACTPMID:37897370 | DOI:10.1080/1744666X.2023.2277864 (Source: Expert Review of Clinical Immunology)
Source: Expert Review of Clinical Immunology - October 28, 2023 Category: Allergy & Immunology Authors: Ahmad Z Al Meslamani Source Type: research

Pan-cancer analysis of the prognostic significance of < em > ACKR2 < /em > expression and the related genetic/epigenetic dysregulations
CONCLUSIONS: ACKR2 expression was associated with favorable prognosis in patients with uveal melanoma and hepatocellular carcinoma. ACKR2 dysregulation might be an accumulated result of gene copy number alterations, transcriptional disruption, and RNA modifications.PMID:37882761 | DOI:10.1080/1744666X.2023.2274361 (Source: Expert Review of Clinical Immunology)
Source: Expert Review of Clinical Immunology - October 26, 2023 Category: Allergy & Immunology Authors: Hongxiu Dong Shijie Zhou Xuxi Chen Xuejie Deng Aiping Fang Source Type: research

Hematological involvement in sarcoidosis: from cytopenias to lymphoma
We present an updated overview of the hematological involvementassociated with sarcoidosis, including a management approach forcytopenias and revisiting the association with hematologicalmalignancies.AREAS COVERED: Theetiology of cytopenias in sarcoidosis can be attributed to two majoretiopathogenic mechanisms: infiltration of hematopoietic organs suchas the spleen and bone marrow, and autoimmune-mediated cytopenias.With respect to the association with hematological malignancies, itrequires careful evaluation of patients from a chronologicalperspective. Patients must be classified into one of three pathogenicscenarios, inc...
Source: Expert Review of Clinical Immunology - October 25, 2023 Category: Allergy & Immunology Authors: Pilar Brito-Zer ón Elyse E Lower Manuel Ramos-Casals Robert P Baughman Source Type: research

Pediatric IgG4-related disease: a descriptive review
Expert Rev Clin Immunol. 2023 Oct 24. doi: 10.1080/1744666X.2023.2274358. Online ahead of print.ABSTRACTINTRODUCTION: IgG4-related disease (IgG4-RD) is an immune-mediated systemic fibroinflammatory condition characterized by serum IgG4 elevation and IgG4-positive plasma cell infiltration into various organs. It generally occurs in elderly males. Pediatric cases have been reported, albeit rarely, accordingly lack of recognition of such cases could delay therapeutic intervention leading to poorer outcomes.AREAS COVERED: The present review is a descriptive review of all published case reports, cohort studies, and reviews of p...
Source: Expert Review of Clinical Immunology - October 24, 2023 Category: Allergy & Immunology Authors: Satoshi Hara Misaki Yoshida Hajime Sanada Yasunori Suzuki Yasuharu Sato Ichiro Mizushima Mitsuhiro Kawano Source Type: research

Eosinophilic esophagitis: does age matter?
Expert Rev Clin Immunol. 2023 Oct 23. doi: 10.1080/1744666X.2023.2274940. Online ahead of print.ABSTRACTINTRODUCTION: Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus with increasing prevalence worldwide. It is a multifactorial disease caused by a combination of immunologic, genetic, and environmental factors. The clinical presentation of EoE varies largely, especially between different age groups. While diagnostic criteria and therapeutic goals are similar in children and adults, there are differences in treatment, with a more cautious approach in children to avoid growth disturbances. In ...
Source: Expert Review of Clinical Immunology - October 23, 2023 Category: Allergy & Immunology Authors: Sara Massironi Alessandra Elvevi Roberto Panceri Giacomo Mulinacci Giacomo Colella Andrea Biondi Pietro Invernizzi Silvio Danese Edoardo Vespa Source Type: research

Intravenous difelikefalin for the treatment of hemodialysis pruritus
Expert Rev Clin Immunol. 2023 Oct 17. doi: 10.1080/1744666X.2023.2272048. Online ahead of print.ABSTRACTINTRODUCTION: Patients with chronic kidney disease (CKD) undergoing hemodialysis often experience significant itch secondary to their condition and a subsequent reduction in their overall quality of life. Current treatments are underwhelming, necessitating the search for new, effective therapeutic options to combat itch in this population.AREAS COVERED: The purpose of this review is to explore the available data for the use of intravenous difelikefalin in patients with CKD undergoing hemodialysis. The pathophysiology of ...
Source: Expert Review of Clinical Immunology - October 17, 2023 Category: Allergy & Immunology Authors: Rami H Mahmoud Omar Mahmoud Gil Yosipovitch Source Type: research