Prescriptions of antidepressants and anxiolytics in France 2012-2022 and changes with the COVID-19 pandemic: interrupted time series analysis
Conclusions
This study showed a protracted trend increase in the consumption of antidepressants since pandemic onset, while increases in anxiolytic consumption were temporary.
Clinical implications
We provide evidence that the COVID-19 pandemic may have had long-lasting consequences on the prevalence and treatment of depression and anxiety disorders, requiring further actions by researchers and policy-makers to address this potential public mental health crisis. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - February 26, 2024 Category: Psychiatry & Psychology Authors: De Bandt, D., Haile, S. R., Devillers, L., Bourrion, B., Menges, D. Tags: Open access, COVID-19 Original research Source Type: research
Understanding effect size: an international online survey among psychiatrists, psychologists, physicians from other medical specialities, dentists and other health professionals
Conclusions and clinical implications
For dichotomous outcomes, presenting the effects in terms of the CER and EER could lead to the most correct interpretation. Relative measures including the risk ratio must be supplemented with absolute measures such as the CER and EER. Effects on continuous outcomes were better understood through standardised mean differences than mean differences. These can also be supplemented by dichotomised CER and EER. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - February 21, 2024 Category: Psychiatry & Psychology Authors: Heimke, F., Furukawa, Y., Siafis, S., Johnston, B. C., Engel, R. R., Furukawa, T. A., Leucht, S. Tags: Open access Statistics Source Type: research
Internet-based behavioural activation therapy versus online psychoeducation for self-reported suicidal ideation in individuals with depression in Indonesia: a secondary analysis of an RCT
Conclusions
In individuals with depression in Indonesia, the GAF-ID intervention was not superior in reducing self-reported SI compared with PE. Also, the association between treatment condition and SI at week 24 was not mediated via BA at week 10.
Clinical implications
This study supports the need for further research on the efficacy of psychological treatments targeting SI in the Southeast Asia context. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - February 20, 2024 Category: Psychiatry & Psychology Authors: Heuschen, C. B. B. C. M., Bolhuis, K., Zantvoord, J. B., Arjadi, R., Denys, D. A. J. P., Nauta, M. H., Lok, A., Bockting, C. L. Tags: Open access Digital mental health Source Type: research
Predictors of increased affective symptoms and suicidal ideation during the COVID-19 pandemic: results from a large-scale study of 14 271 Thai adults
Background
Increasing data suggest emergent affective symptoms during the COVID-19 pandemic.
Objectives
To study the impact of the COVID-19 pandemic on affective symptoms and suicidal ideation in Thai adults.
Methods
The Collaborative Outcomes Study on Health and Functioning during Infection Times uses non-probability sampling (chain referring and voluntary response sampling) and stratified probability sampling to identify risk factors of mental health problems and potential treatment targets to improve mental health outcomes during pandemics.
Findings
Analysing 14 271 adult survey participants across all four waves of ...
Source: Evidence-Based Mental Health - February 19, 2024 Category: Psychiatry & Psychology Authors: Supasitthumrong, T., Maes, M., Tunvirachaisakul, C., Rungnirundorn, T., Zhou, B., Li, J., Wainipitapong, S., Ratanajaruraks, A., Nimnuan, C., Kanchanatawan, B., Thompson, T., Solmi, M., Correll, C. Tags: Open access, COVID-19 Adult mental health Source Type: research
All-cause and suicide mortalities among adolescents and young adults who contacted specialised gender identity services in Finland in 1996-2019: a register study
Conclusions
Clinical gender dysphoria does not appear to be predictive of all-cause nor suicide mortality when psychiatric treatment history is accounted for.
Clinical implications
It is of utmost importance to identify and appropriately treat mental disorders in adolescents experiencing gender dysphoria to prevent suicide. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - February 17, 2024 Category: Psychiatry & Psychology Authors: Ruuska, S.-M., Tuisku, K., Holttinen, T., Kaltiala, R. Tags: Open access Child and adolescent mental health Source Type: research
Are web-based stress management interventions effective as an indirect treatment for depression? An individual participant data meta-analysis of six randomised trials
Conclusions
Our results indicate that web-based stress management can serve as an indirect treatment, yielding effects comparable with direct interventions for depression. Further research is needed to determine if such formats can indeed increase the utilisation of evidence-based treatment, and to corroborate the favourable effects for human guidance.
Study registration
Open material repository: osf.io/dbjc8, osf.io/3qtbe.
Trial registration number
German Clinical Trial Registration (DRKS): DRKS00004749, DRKS00005112, DRKS00005384, DRKS00005687, DRKS00005699, DRKS00005990. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - February 13, 2024 Category: Psychiatry & Psychology Authors: Harrer, M., Nixon, P., Sprenger, A. A., Heber, E., Boss, L., Heckendorf, H., Buntrock, C., Ebert, D. D., Lehr, D. Tags: Open access Digital mental health Source Type: research
Influence of study characteristics, methodological rigour and publication bias on efficacy of pharmacotherapy in obsessive-compulsive disorder: a systematic review and meta-analysis of randomised, placebo-controlled trials
Conclusions
Our findings reveal superiority of clomipramine over SSRIs, even after adjusting for risk of bias. Effect sizes may be attenuated when considering publication bias and methodological rigour, emphasising the importance of robust studies to guide clinical utility of OCD pharmacotherapy.
PROSPERO registration number
CRD42023394924. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - February 12, 2024 Category: Psychiatry & Psychology Authors: Cohen, S. E., Zantvoord, J. B., Storosum, B. W. C., Mattila, T. K., Daams, J., Wezenberg, B., de Boer, A., Denys, D. A. J. P. Tags: Open access Pharmacological treatments Source Type: research
Estimating the joint association of adverse childhood experiences and asthma with subsequent depressive symptoms: a marginal structural modelling approach
Conclusions
These findings suggest that asthma amplifies the risk of depressive symptoms associated with ACEs.
Clinical implications
Prevention and treatment of asthma, along with establishing preventive environments and services against ACEs, are effective in mitigating the potential burden of ACEs on mental health. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - February 2, 2024 Category: Psychiatry & Psychology Authors: Takemura, Y., Sato, K., Liang, R., Isobe, M., Kondo, N., Inoue, K. Tags: Open access Adult mental health Source Type: research
Framework for understanding movement and physical activity in patients diagnosed with psychosis
Conclusions and clinical implications
The 5 P (Purpose, Predictions, Present state, Provision and Process Physical Activity Framework) for understanding movement and physical activity for people diagnosed with psychosis has the potential to inform future research and guide interventions. A checklist is provided for clinicians to help foster change in activity levels. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - February 1, 2024 Category: Psychiatry & Psychology Authors: Diamond, R., Waite, F., Boylan, A.-M., Hicks, A., Kabir, T., Freeman, D. Tags: Open access Adult mental health Source Type: research
Single session of interpretation bias modification helped to improve fear of COVID-19 and COVID-19-related post-traumatic stress symptoms
Conclusions
IMP could improve negative interpretations and fear related to COVID-19 and might help to ameliorate PTSS.
Clinical implications
The role of PTSS-related emotion should be considered when exploring the effectiveness of IMP. IMP is a flexible approach that can be tailored to the specific characteristics of the traumatic event, which makes it suitable for a broader range of traumatised individuals. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - February 1, 2024 Category: Psychiatry & Psychology Authors: Zhang, F., Xu, H., Liu, Q., Sun, Y., Yan, W., Ouyang, H., Liu, W. Tags: Open access, COVID-19 Psychotherapies Source Type: research
Waiting-list interventions for children and young people using child and adolescent mental health services: a systematic review
Conclusions
There is limited research exploring waiting list interventions, however, the findings from small-scale studies are promising. Further research using robust study designs and real-world implementation studies are warranted. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - February 1, 2024 Category: Psychiatry & Psychology Authors: Valentine, A. Z., Hall, S. S., Sayal, K., Hall, C. L. Tags: Open access Child and adolescent mental health Source Type: research
Quality of melatonin use in children and adolescents: findings from a UK clinical audit
Conclusions
Melatonin was predominantly prescribed for evidence-based clinical indications, but the clinical review and monitoring of this treatment fell short of best practice.
Clinical implications
With limited methodical review of melatonin use in their patients, clinicians will fail to garner reliable information on its risks and benefits for individual patients. The lack of such practice-based evidence may increase the risk of melatonin being inappropriately targeted or continued despite being ineffective or no longer indicated. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - January 22, 2024 Category: Psychiatry & Psychology Authors: Paton, C., Gringras, P., Ruan, A., Liew, A., Rendora, O., Bove, G., Barnes, T. R. E. Tags: Open access Child and adolescent mental health Source Type: research
Beneficial and harmful effects of tricyclic antidepressants for adults with major depressive disorder: a systematic review with meta-analysis and trial sequential analysis
Conclusions
The long-term effects of tricyclic antidepressants and the effects on quality of life are unknown. Short-term results suggest that tricyclic antidepressants may reduce depressive symptoms while also increasing the risks of serious adverse events, but these results were based on low and very low certainty evidence.
PROSPERO registration number
CRD42021226161. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - January 22, 2024 Category: Psychiatry & Psychology Authors: Kamp, C. B., Petersen, J. J., Faltermeier, P., Juul, S., Siddiqui, F., Barbateskovic, M., Kristensen, A. T., Moncrieff, J., Horowitz, M. A., Hengartner, M. P., Kirsch, I., Gluud, C., Jakobsen, J. C. Tags: Open access Pharmacological treatments Source Type: research
Genome-wide DNA methylation risk scores for schizophrenia derived from blood and brain tissues further explain the genetic risk in patients stratified by polygenic risk scores for schizophrenia and bipolar disorder
Conclusions
These findings suggest that the MRS is a potential genetic marker in understanding SZ, particularly in patients with a genetic SZ risk. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - January 11, 2024 Category: Psychiatry & Psychology Authors: Ohi, K., Shimada, M., Soda, M., Nishizawa, D., Fujikane, D., Takai, K., Kuramitsu, A., Muto, Y., Sugiyama, S., Hasegawa, J., Kitaichi, K., Ikeda, K., Shioiri, T. Tags: Open access Genetics and genomics Source Type: research
A chatbot to improve adherence to internet-based cognitive-behavioural therapy among workers with subthreshold depression: a randomised controlled trial
Conclusions
Combining iCBT with a chatbot increased participants’ iCBT completion rate.
Clinical implications
Encouraging messages from the chatbot could improve participation in an iCBT programme. Further studies are needed to investigate whether chatbots can improve adherence to the programme in the long term and to assess their impact on depression, anxiety and well-being.
Trial registration number
UMIN000047621. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - January 10, 2024 Category: Psychiatry & Psychology Authors: Yasukawa, S., Tanaka, T., Yamane, K., Kano, R., Sakata, M., Noma, H., Furukawa, T. A., Kishimoto, T. Tags: Open access Digital mental health Source Type: research
