Evidence-Based Mental Health This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Components of smartphone cognitive-behavioural therapy for subthreshold depression among 1093 university students: a factorial trial
Conclusions There was significant reduction in depression for all participants regardless of the presence and absence of the examined iCBT components. Clinical implication We cannot yet make evidence-based recommendations for specific iCBT components. We suggest that future iCBT optimisation research should scrutinise the amount and structure of components to examine. Trial registration number UMINCTR-000031307. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - December 19, 2022 Category: Psychiatry & Psychology Authors: Sakata, M., Toyomoto, R., Yoshida, K., Luo, Y., Nakagami, Y., Uwatoko, T., Shimamoto, T., Tajika, A., Suga, H., Ito, H., Sumi, M., Muto, T., Ito, M., Ichikawa, H., Ikegawa, M., Shiraishi, N., Watanabe, T., Sahker, E., Ogawa, Y., Hollon, S. D., Collins, L. Tags: Open access Psychotherapies Source Type: research

Digital cognitive-behavioural therapy to reduce suicidal ideation and behaviours: a systematic review and meta-analysis of individual participant data
Conclusions The current evidence indicates that iCBT is effective in reducing suicidal ideation irrespective of age, gender and previous suicide attempts. Future studies should rigorously assess suicidal behaviour and drop-out reasons. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - December 19, 2022 Category: Psychiatry & Psychology Authors: Büscher, R., Beisemann, M., Doebler, P., Micklitz, H. M., Kerkhof, A., Cuijpers, P., Batterham, P. J., Calear, A. L., Christensen, H., De Jaegere, E., Domhardt, M., Erlangsen, A., Eylem van Bergeijk, O., Hill, R., Lungu, A., Mühlmann, C., Tags: Open access Systematic review Source Type: research

Mental healthcare in primary and community-based settings: evidence beyond the WHO Mental Health Gap Action Programme (mhGAP) Intervention Guide
Conclusions The literature beyond the mhGAP-IG is extensive and shares common findings. Future priorities are less-studied regions, interventions for severe mental illness, exploring ways that mhGAP-IG and alternative approaches complement each other in different contexts and scaling-up mental health integration. PROSPERO registration number CRD42017068459. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - December 19, 2022 Category: Psychiatry & Psychology Authors: Keynejad, R. C., Spagnolo, J., Thornicroft, G. Tags: Open access Systematic review Source Type: research

Vitruvian plot: a visualisation tool for multiple outcomes in network meta-analysis
Conclusions The Vitruvian plot allows reporting of multiple outcomes from NMAs, with colourings appropriate to inform credibility of the presented evidence. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - December 19, 2022 Category: Psychiatry & Psychology Authors: Ostinelli, E. G., Efthimiou, O., Naci, H., Furukawa, T. A., Leucht, S., Salanti, G., Wainwright, L., Zangani, C., De Crescenzo, F., Smith, K., Stevens, K., Liu, Q., Cipriani, A. Tags: Open access, Editor's choice, EBMH Statistics in Practice Source Type: research

Associations between antipsychotics and risk of violent crimes and suicidal behaviour in personality disorder
Conclusions Treatment with antipsychotics was associated with reduced risks for violent crime suspicions and suicidal behaviour among individuals with personality disorder. Clinical implications Potential effects of antipsychotics on suicidal behaviour and violence should be taken into account when considering treatment options for people with personality disorders. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - December 19, 2022 Category: Psychiatry & Psychology Authors: Herttua, K., Crawford, M., Paljarvi, T., Fazel, S. Tags: Open access Pharmacological treatments Source Type: research

Can we mitigate the psychological impacts of social isolation using behavioural activation? Long-term results of the UK BASIL urgent public health COVID-19 pilot randomised controlled trial and living systematic review
Discussion We delivered a pilot trial of a behavioural intervention targeting loneliness and depression; achieving long-term follow-up. Living meta-analysis provides strong evidence of short-term benefit for loneliness and depression for cognitive and/or behavioural approaches. A fully powered BASIL trial is underway. Clinical implications Scalable behavioural and cognitive approaches should be considered as population-level strategies for depression and loneliness on the basis of a living systematic review. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - December 19, 2022 Category: Psychiatry & Psychology Authors: Littlewood, E., McMillan, D., Chew Graham, C., Bailey, D., Gascoyne, S., Sloane, C., Burke, L., Coventry, P., Crosland, S., Fairhurst, C., Henry, A., Hewitt, C., Baird, K., Ryde, E., Shearsmith, L., Traviss-Turner, G., Woodhouse, R., Webster, J., Meader, Tags: Open access, COVID-19 Psychosocial interventions Source Type: research

Important adverse events to be evaluated in antidepressant trials and meta-analyses in depression: a large international preference study including patients and healthcare professionals
Conclusions These most important NSAEs should be systematically reported in antidepressant trials. Clinical implications The most important NSAEs should contribute to the core outcome set for harms in depression. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - December 19, 2022 Category: Psychiatry & Psychology Authors: Chevance, A., Tomlinson, A., Ravaud, P., Touboul, S., Henshall, C., Tran, V.-T., Cipriani, A. Tags: Open access Pharmacological treatments Source Type: research

Guided digital health intervention for depression in Lebanon: randomised trial
Conclusions Guided digital mental health interventions can be effective in the treatment of depression in communities exposed to adversities in LMICs, although some uncertainty remains because of high attrition. Clinical implications Guided digital mental health interventions should be considered for implementation in LMICs. Trial registration number ClinicalTrials.gov NCT03720769. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - December 19, 2022 Category: Psychiatry & Psychology Authors: Cuijpers, P., Heim, E., Ramia, J. A., Burchert, S., Carswell, K., Cornelisz, I., Knaevelsrud, C., Noun, P., van Klaveren, C., vant Hof, E., Zoghbi, E., van Ommeren, M., El Chammay, R. Tags: Open access Digital mental health Source Type: research

Comparison of prediction methods for treatment continuation of antipsychotics in children and adolescents with schizophrenia
Conclusions All prediction models showed similar performance in predicting the treatment continuation of antipsychotics. Application of prediction models might be helpful for evidence-based decision-making in antipsychotic treatment. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - December 19, 2022 Category: Psychiatry & Psychology Authors: Jeon, S. M., Cho, J., Lee, D. Y., Kwon, J.-W. Tags: Open access Digital mental health Source Type: research

Risk prediction model for cardiovascular diseases in adults initiating pharmacological treatment for attention-deficit/hyperactivity disorder
Conclusions The inclusion of the novel CVD risk factors may provide a better prediction of CVDs in this population compared with traditional CVD predictors only, when the model is used with a continuous risk score. External validation studies and studies assessing clinical impact of the model are warranted. Clinical implications Individuals initiating pharmacological treatment of ADHD at higher risk of developing CVDs should be more closely monitored. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - November 17, 2022 Category: Psychiatry & Psychology Authors: Dobrosavljevic, M., Fazel, S., Du Rietz, E., Li, L., Zhang, L., Chang, Z., Jernberg, T., Faraone, S. V., Jendle, J., Chen, Q., Brikell, I., Larsson, H. Tags: Open access Pharmacological treatments Source Type: research

Self-harm, somatic disorders and mortality in the 3 years following a hospitalisation in psychiatry in adolescents and young adults
Conclusions The first 3 years following psychiatric hospital admission of young people is a period of high risk for self-harm, somatic disorders and premature mortality. Clinical implications Attention to these negative outcomes urgently needs to be incorporated in aftercare policies. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - November 17, 2022 Category: Psychiatry & Psychology Authors: Jollant, F., Goueslard, K., Hawton, K., Quantin, C. Tags: Open access Student mental health Source Type: research

Association between mirtazapine use and serious self-harm in people with depression: an active comparator cohort study using UK electronic health records
Conclusions There was no evidence for a difference in risk between mirtazapine and SSRIs or venlafaxine after accounting for baseline characteristics. The higher risk in the mirtazapine versus the amitriptyline group might reflect residual confounding if amitriptyline is avoided in people considered at risk of self-harm. Clinical implications Addressing baseline risk factors and careful monitoring might improve outcomes for people at risk of serious self-harm. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - November 17, 2022 Category: Psychiatry & Psychology Authors: Joseph, R. M., Jack, R. H., Morriss, R., Knaggs, R. D., Butler, D., Hollis, C., Hippisley-Cox, J., Coupland, C. Tags: Open access Adult mental health Source Type: research