Prevalence estimates of major depressive disorder in 27 European countries from the European Health Interview Survey: accounting for imperfect diagnostic accuracy of the PHQ-8
Conclusions
Prevalence estimation needs to account for imperfect diagnostic accuracy.
Clinical implications
Major depression prevalence in European countries is likely lower than previously reported on the basis of the EHIS survey. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - April 6, 2023 Category: Psychiatry & Psychology Authors: Fischer, F., Zocholl, D., Rauch, G., Levis, B., Benedetti, A., Thombs, B., Rose, M., Kostoulas, P. Tags: Open access Original research Source Type: research
Exploring the efficacy of psychotherapies for depression: a multiverse meta-analysis
Conclusions and Clinical Implications
The multiverse meta-analysis revealed the overall robustness of the effectiveness of psychotherapies for depression. Notably, meta-analyses that included studies with a high risk of bias, compared the intervention with wait-list control groups, and not correcting for publication bias produced larger effect sizes. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - March 13, 2023 Category: Psychiatry & Psychology Authors: Plessen, C. Y., Karyotaki, E., Miguel, C., Ciharova, M., Cuijpers, P. Tags: Psychotherapies Source Type: research
Decoding fMRI alcohol cue reactivity and its association with drinking behaviour
Conclusions
These findings provide insight into how AUD individuals differently decode alcohol cues compared with healthy participants, from the componential processes of visual object recognition and reward appraisal.
Clinical implications
The identified patterns are suggested as biomarkers and potential therapeutic targets in AUD. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - February 23, 2023 Category: Psychiatry & Psychology Authors: Tan, H., Gerchen, M. F., Bach, P., Lee, A. M., Hummel, O., Sommer, W., Kirsch, P., Kiefer, F., Vollstädt-Klein, S. Tags: Open access Imaging studies Source Type: research
What I stand for as BMJ Mental Health editor
Welcome to BMJ Mental Health. In January 2023, Evidence-Based Mental Health (EBMH) has changed its name to BMJ Mental Health, after 25 years of activity (the journal was founded in 1998) and after recently becoming one of the top 10 psychiatric journals in terms of impact factor. BMJ Mental Health is now online only and entirely open access. Changing name is not just a rebranding exercise. It is a fantastic opportunity to do things better and reach a wider audience of mental health clinicians and researchers. In the last year, EBMH published a variety of original articles, spanning from global health,1 self-harm2 and suici...
Source: Evidence-Based Mental Health - February 15, 2023 Category: Psychiatry & Psychology Authors: Cipriani, A. Tags: Open access Editorials Source Type: research
Symptom-specific effects of counselling for depression compared to cognitive-behavioural therapy
Conclusions
CfD and CBT for depression have differential effects on symptoms demonstrating specific mechanisms of change.
Clinical implications
CBT was uniquely associated with changes in symptoms associated with anxiety and may be better suited to those with anxiety symptoms comorbid to their depression. When assessing change, the baseline should be the first therapy session, not the pretreatment assessment. Residual change scores should be preferred over difference score methods. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - February 15, 2023 Category: Psychiatry & Psychology Authors: O'Driscoll, C., Buckman, J. E. J., Saunders, R., Ellard, S., Naqvi, S. A., Singh, S., Wheatley, J., Pilling, S. Tags: Open access Psychotherapies Source Type: research
metaumbrella: the first comprehensive suite to perform data analysis in umbrella reviews with stratification of the evidence
Conclusion
To facilitate the use of this package, even for researchers unfamiliar with R, we also provide a JAMOVI module and an open-access, browser-based graphical interface that allow use of the core functions of the package with a few mouse clicks. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - February 15, 2023 Category: Psychiatry & Psychology Authors: Gosling, C. J., Solanes, A., Fusar-Poli, P., Radua, J. Tags: Open access, EBMH Statistics in Practice Source Type: research
Peer-provided psychological intervention for Syrian refugees: results of a randomised controlled trial on the effectiveness of Problem Management Plus
Conclusions
PM+ effectively reduces symptoms of CMDs among Syrian refugees. A strength was high retention at follow-up. Generalisability is limited by predominantly including refugees with a resident permit.
Clinical implications
Peer-provided psychological interventions should be considered for scale-up in HICs. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - February 8, 2023 Category: Psychiatry & Psychology Authors: de Graaff, A. M., Cuijpers, P., Twisk, J. W. R., Kieft, B., Hunaidy, S., Elsawy, M., Gorgis, N., Bouman, T. K., Lommen, M. J. J., Acarturk, C., Bryant, R., Burchert, S., Dawson, K. S., Fuhr, D. C., Hansen, P., Jordans, M., Knaevelsrud, C., McDaid, D., Mor Tags: Open access Psychosocial interventions Source Type: research
Examining the Lancet Commission risk factors for dementia using Mendelian randomisation
Conclusions and implications
Post hoc analysis indicated that the apparent protective effects of smoking, obesity and blood pressure were a result of survivor bias. The findings from this study did not support those presented by the Lancet Commission. Evidence from causal inference studies should be considered alongside evidence from epidemiological studies and incorporated into reviews of the literature. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - February 7, 2023 Category: Psychiatry & Psychology Authors: Desai, R., John, A., Saunders, R., Marchant, N. L., Buckman, J. E. J., Charlesworth, G., Zuber, V., Stott, J. Tags: Open access Old age psychiatry Source Type: research
Comparison of antipsychotic dose equivalents for acute bipolar mania and schizophrenia
Conclusions
Antipsychotic drugs have been considered first-line treatment for acute mania, warranting specific dose equivalence for scientific and clinical purposes. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - February 7, 2023 Category: Psychiatry & Psychology Authors: Yu, C.-L., Carvalho, A. F., Thompson, T., Tsai, T.-C., Tseng, P.-T., Hsu, C.-W., Hsu, T.-W., Liang, C.-S. Tags: Open access Statistics Source Type: research
Vitruvian plot: a visualisation tool for multiple outcomes in network meta-analysis
Conclusions
The Vitruvian plot allows reporting of multiple outcomes from NMAs, with colourings appropriate to inform credibility of the presented evidence. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - December 19, 2022 Category: Psychiatry & Psychology Authors: Ostinelli, E. G., Efthimiou, O., Naci, H., Furukawa, T. A., Leucht, S., Salanti, G., Wainwright, L., Zangani, C., De Crescenzo, F., Smith, K., Stevens, K., Liu, Q., Cipriani, A. Tags: Open access, Editor's choice, EBMH Statistics in Practice Source Type: research
Associations between antipsychotics and risk of violent crimes and suicidal behaviour in personality disorder
Conclusions
Treatment with antipsychotics was associated with reduced risks for violent crime suspicions and suicidal behaviour among individuals with personality disorder.
Clinical implications
Potential effects of antipsychotics on suicidal behaviour and violence should be taken into account when considering treatment options for people with personality disorders. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - December 19, 2022 Category: Psychiatry & Psychology Authors: Herttua, K., Crawford, M., Paljarvi, T., Fazel, S. Tags: Open access Pharmacological treatments Source Type: research
Can we mitigate the psychological impacts of social isolation using behavioural activation? Long-term results of the UK BASIL urgent public health COVID-19 pilot randomised controlled trial and living systematic review
Discussion
We delivered a pilot trial of a behavioural intervention targeting loneliness and depression; achieving long-term follow-up. Living meta-analysis provides strong evidence of short-term benefit for loneliness and depression for cognitive and/or behavioural approaches. A fully powered BASIL trial is underway.
Clinical implications
Scalable behavioural and cognitive approaches should be considered as population-level strategies for depression and loneliness on the basis of a living systematic review. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - December 19, 2022 Category: Psychiatry & Psychology Authors: Littlewood, E., McMillan, D., Chew Graham, C., Bailey, D., Gascoyne, S., Sloane, C., Burke, L., Coventry, P., Crosland, S., Fairhurst, C., Henry, A., Hewitt, C., Baird, K., Ryde, E., Shearsmith, L., Traviss-Turner, G., Woodhouse, R., Webster, J., Meader, Tags: Open access, COVID-19 Psychosocial interventions Source Type: research
Important adverse events to be evaluated in antidepressant trials and meta-analyses in depression: a large international preference study including patients and healthcare professionals
Conclusions
These most important NSAEs should be systematically reported in antidepressant trials.
Clinical implications
The most important NSAEs should contribute to the core outcome set for harms in depression. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - December 19, 2022 Category: Psychiatry & Psychology Authors: Chevance, A., Tomlinson, A., Ravaud, P., Touboul, S., Henshall, C., Tran, V.-T., Cipriani, A. Tags: Open access Pharmacological treatments Source Type: research
Guided digital health intervention for depression in Lebanon: randomised trial
Conclusions
Guided digital mental health interventions can be effective in the treatment of depression in communities exposed to adversities in LMICs, although some uncertainty remains because of high attrition.
Clinical implications
Guided digital mental health interventions should be considered for implementation in LMICs.
Trial registration number
ClinicalTrials.gov NCT03720769. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - December 19, 2022 Category: Psychiatry & Psychology Authors: Cuijpers, P., Heim, E., Ramia, J. A., Burchert, S., Carswell, K., Cornelisz, I., Knaevelsrud, C., Noun, P., van Klaveren, C., vant Hof, E., Zoghbi, E., van Ommeren, M., El Chammay, R. Tags: Open access Digital mental health Source Type: research
Comparison of prediction methods for treatment continuation of antipsychotics in children and adolescents with schizophrenia
Conclusions
All prediction models showed similar performance in predicting the treatment continuation of antipsychotics. Application of prediction models might be helpful for evidence-based decision-making in antipsychotic treatment. (Source: Evidence-Based Mental Health)
Source: Evidence-Based Mental Health - December 19, 2022 Category: Psychiatry & Psychology Authors: Jeon, S. M., Cho, J., Lee, D. Y., Kwon, J.-W. Tags: Open access Digital mental health Source Type: research
