Movement artifacts in pediatric cutaneous ultrasonography.
CONCLUSIONS: Cutaneous ultrasonography without sedation can be particularly difficult in children aged between 4 and 12 months, especially when lesions are located on the head and neck and a Doppler exam is required. When assessing congenital lesions, the first four months of life are ideal for a first examination. PMID: 30710896 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - January 15, 2019 Category: Dermatology Authors: Rodríguez Bandera AI, Stewart N, De la Cruz Troca JJ, Andrés Esteban EM, Feito Rodríguez M, De Lucas Laguna R Tags: Dermatol Online J Source Type: research

The doctor's office is the best setting for most cutaneous procedures.
Abstract Although most dermatologic procedures are done in an office setting, some providers are performing them instead in ambulatory surgery centers (ASCs). This relocation of care comes with significantly higher expenses for patients and insurers. Compounding the issue of increased costs is the paucity of evidence demonstrating better outcomes associated with the use of ASCs. The most common cutaneous procedures have low complication rates when performed in an office setting and regular use of ASCs for these procedures is not justified. PMID: 30710897 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - January 15, 2019 Category: Dermatology Authors: Anderson HJ, Keller M Tags: Dermatol Online J Source Type: research

An assessment of social media usage by dermatology residency programs.
Abstract Despite the increasing popularity of social media, the activity of dermatology residency programs on top social media platforms has never been investigated to our knowledge. We investigated a total of 126 dermatology residency programs to assess their presence and popularity on social media. Searches were conducted to identify dermatology residency departments' accounts on Facebook, Twitter, and Instagram. The number of Facebook likes, Twitter followers, and Instagram followers were recorded. Of the 126 dermatology residency programs, 29 (23%) were active on Facebook, 14 (11%) on Twitter, and 9 (7%) on In...
Source: Dermatol Online J - January 15, 2019 Category: Dermatology Authors: St Claire KM, Rietcheck HR, Patel RR, Dellavalle RP Tags: Dermatol Online J Source Type: research

Pyoderma gangrenosum: a presenting sign of myelodysplastic syndrome in undiagnosed Fanconi anemia.
Abstract A 26-year-old man with a history of congenital bilateral microtia, unilateral renal agenesis, left aural atresia, and right external auditory canal occlusion admitted for right rib cartilage graft harvest and left ear re-construction. Following surgery, an ulceration with violaceous borders and a yellow fibrinous base unresponsive to broad-spectrum antibiotics developed at the harvest site. The wound was expanding and not responsive to systemic broad-spectrum antibiotics. Biopsy revealed a dense dermal infiltrate of neutrophils with negative tissue cultures consistent with pyoderma gangrenosum (PG). He wa...
Source: Dermatol Online J - January 15, 2019 Category: Dermatology Authors: Kandula P, Shah KM, Wolverton JE, Le C, Wolverton SE Tags: Dermatol Online J Source Type: research

Bullous lupus erythematosus with an erythema gyratum repens-like pattern.
We present a 21-year-old woman with erythematosus, polycyclic plaques with vesiculobullae along the periphery, creating an erythema gyratum repens-like pattern on acral regions. The cutaneous biopsy, analytical, and autoimmune studies support the diagnosis of systemic lupus erythematosus. Dapsone and glucocorticosteroids were given with prompt resolution of the lesions within two weeks. To our knowledge this is the first case of bullous lupus erythematosus with this atypical acral presentation. PMID: 30710900 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - January 15, 2019 Category: Dermatology Authors: Da Silva Sousa AC, Campos M, Oliveira A, Menezes N, Tente D, Baptista A Tags: Dermatol Online J Source Type: research

Fibro-osseous pseudotumor on the hyponychium of the great toe.
We present a patient with fibro-osseous pseudotumor of the great toe, which had no recurrence following excision. PMID: 30710901 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - January 15, 2019 Category: Dermatology Authors: Rosales Santillan M, Tschen JA Tags: Dermatol Online J Source Type: research

Koebner phenomenon: pemphigus vulgaris following Mohs micrographic surgery.
We present a 65-year-old man with Koebnerized pemphigus vulgaris after Mohs microscopic surgery for a basal cell carcinoma. We present this case to heighten awareness of the phenomenon in the dermatological community. PMID: 30710902 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - January 15, 2019 Category: Dermatology Authors: Hattier G, Beggs S, Sahu J, Trufant J, Jones E Tags: Dermatol Online J Source Type: research

Rapid progression of immune dysregulation in an HIV-infected patient with S ézary syndrome.
Rapid progression of immune dysregulation in an HIV-infected patient with Sézary syndrome. Dermatol Online J. 2019 Jan 15;25(1): Authors: Dadoo AS, Steenkamp I Abstract A 44-year-old man known to have human immunodeficiency virus (HIV) infection presented to our clinic with erythroderma, generalized lymphadenopathy, and cutaneous nodules and tumors. After a series of investigations, we confirmed that he had Sézary syndrome. In this paper we describe the immune alterations that occur in both Sézary Syndrome and HIV infection and how these changes together resulted in rapid and over...
Source: Dermatol Online J - January 15, 2019 Category: Dermatology Authors: Dadoo AS, Steenkamp I Tags: Dermatol Online J Source Type: research

A pink enlarging plaque on the plantar foot: amelanotic acral lentiginous melanoma.
We describe a man in his 50s with a twenty-year history of a skin-colored plaque on the right plantar foot; after enlargement and failure of wart treatment, a shave biopsy revealed an amelanotic melanoma. A subsequent wide local excision and sentinel lymph node biopsy revealed melanoma in 4 lymph nodes and the patient underwent an abbreviated course of interferon-alpha therapy. The patient remained stable until 2 ? years after diagnosis, at which time he presented with in-transit metastases on the foot and right thigh; he has since been stable on nivolumab. This case represents the challenge of diagnosing amelanotic melano...
Source: Dermatol Online J - January 15, 2019 Category: Dermatology Authors: Okhovat JP, Tahan SR, Kim CC Tags: Dermatol Online J Source Type: research

Perianal purpuric plaques revealing an amyloid light-chain amyloidosis: case report and review of the literature.
We present a 71-year-old man that presented to our department because of exuberant purpuric plaques in the anogenital area as the first manifestation of an amyloid light-chain (AL) amyloidosis. The multi-organ involvement in addition to rapid clinical deterioration precipitated the patient's death four months later. PMID: 30710905 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - January 15, 2019 Category: Dermatology Authors: Lopes S, Nogueira A, Gullo I, Pardal J, Lopes JM, Azevedo F Tags: Dermatol Online J Source Type: research

Appearance of lentigines in psoriasis patient treated with guselkumab.
Abstract Development of lentigines in areas of resolving psoriatic plaques is a rare phenomenon that has been reported following various treatment modalities including phototherapy, topical therapies, and biologics. Although the exact mechanism is unknown, evidence suggests that the cause may be multifactorial, with factors such as skin type, sun exposure, inflammation, and immunologic cytokines all playing a potential role. Herein, we present the first reported case of a patient developing multiple lentigines following treatment of psoriasis with the IL-23 inhibitor guselkumab. PMID: 30710906 [PubMed - in pr...
Source: Dermatol Online J - January 15, 2019 Category: Dermatology Authors: Lee EB, Reynolds KA, Pithadia DJ, Wu JJ Tags: Dermatol Online J Source Type: research

CELLULITIS: A mnemonic to increase accuracy of cellulitis diagnosis.
Abstract Cellulitis, a bacterial infection of the skin and subcutaneous tissue, is often misdiagnosed. Cellulitis accounts for a large number of all infectious disease-related hospitalizations in the U.S. Cellulitis can be challenging to diagnose since it lacks pathognomonic findings. We reviewed all articles on cellulitis within the last 20 years that included a statistical analysis, with odds ratios (OR), of specific clinical features of cellulitis. We then constructed a mnemonic encompassing the features with the highest odds ratios. Our mnemonic is CELLULITIS for cellulitis history, edema, local warmth, lympha...
Source: Dermatol Online J - January 15, 2019 Category: Dermatology Authors: Neill BC, Stoecker WV, Hassouneh R, Rajpara A, Aires DJ Tags: Dermatol Online J Source Type: research

Over-the-counter light therapy for acne: a cross-sectional retrospective analysis.
Abstract Acne vulgaris affects a large portion of the population and drives many patients to seek over-the-counter (OTC) treatments. Light-emitting diode (LED) therapy has recently emerged as a potential therapeutic option for inflammatory acne. We used the U.S. Food and Drug Administration (FDA) 510(k) premarket submission database to assess the growth in OTC LED therapy devices for treatment of acne. We also used Google Trends data in searches for "acne light therapy mask" to characterize growth in consumer interest in these devices. Overall, 35 LED devices received pre-market approval from 2000 to 201...
Source: Dermatol Online J - January 15, 2019 Category: Dermatology Authors: Seth D, Wang S, Ezaldein HH, Merati M, Scott JF Tags: Dermatol Online J Source Type: research

Photodamage spares the distal digits owing to primate-like hand flexion.
Abstract Sun-exposed areas of the body - including the face, neck, and extensor forearms - are chronically exposed to UV light and display signs of photoaging. The skin distal to the proximal interphalangeal (PIP) joint is, however, typically spared owing to the natural rest position of the hand. The inward curvature of the fingers, termed the finger flexion cascade, orients the skin distal to the PIP joint toward the ground as in knuckle-walking primates. The near constant protection of this area of skin from sun may reflect our primate ancestry, the daily activities of which included swinging through trees and k...
Source: Dermatol Online J - January 15, 2019 Category: Dermatology Authors: Dorrell DN, Feldman SR Tags: Dermatol Online J Source Type: research

Dermatology and anatomy laboratory: comparing three formats of integration.
CONCLUSIONS: This brief teaching intervention illustrates an approach to introducing dermatologic entities within the foundational science curriculum of the first year of medical school. PMID: 30677791 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 15, 2018 Category: Dermatology Authors: Yang CY, Zumwalt AC, Larson AR Tags: Dermatol Online J Source Type: research

Dermatology on YouTube - an update and analysis of new trends.
Abstract Because YouTube is one of the most popular search engines, it is an instrumental tool to stay up to date on the most relevant dermatology trends and content in order to better direct patients and improve health outcomes. Twelve select terms (i.e. Dermatology, Sun protection, Skin cancer awareness, Skin cancer, Skin condition, Sun safety, Tanning, Melanoma, Basal cell carcinoma, Squamous cell carcinoma, Skin cancer treatment, Skin cancer prevention) were searched on YouTube. Overall, the results included 240 videos with over 160 million views. Educational content was most prevalent at 35% of the total sear...
Source: Dermatol Online J - December 15, 2018 Category: Dermatology Authors: St Claire KM, Rietcheck HR, Patel RR, Dunnick C, Dellavalle RP Tags: Dermatol Online J Source Type: research

Erythema nodosum and sarcoid granulomas - letting the cat out of the bag.
cute; Abstract A 41-year-old woman presented with a violaceous papule on the dorsum of the hand, large ipsilateral axillary lymphadenopathy, and tender, erythematous, subcutaneous nodules on the legs. Accompanying signs included fever, ankle swelling, and bilateral red eye. She recalled having a previous exposure to kittens one month before and had a positive family history for sarcoidosis. Histological examination of the hand lesion showed sarcoidal granulomas with positive Bartonella henselae DNA, whereas a biopsy done on the leg nodules was compatible with erythema nodosum. Cat scratch disease (CSD) typically p...
Source: Dermatol Online J - December 15, 2018 Category: Dermatology Authors: Morgado F, Batista M, Coutinho I, Cardoso JC, Tellechea Ó Tags: Dermatol Online J Source Type: research

Folliculotropic mycosis fungoides.
We report a case of an 83-year-old woman with folliculotropic MF characterized by erythematous, scaly plaques on the forehead along with poliosis and alopecia of the right medial eyebrow. PMID: 30677794 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 15, 2018 Category: Dermatology Authors: Feng H, Beasley J, Meehan S, Liebman TN Tags: Dermatol Online J Source Type: research

Generalized essential telangiectasia.
We report a case of generalized essential telangiectasia in an otherwise healthy 49-year-old man. PMID: 30677795 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 15, 2018 Category: Dermatology Authors: Wiznia LE, Steuer AB, Penn LA, Meehan SA, Femia AN Tags: Dermatol Online J Source Type: research

Lichen planus pigmentosus.
We report a case of LPP of two years duration in a 67-year-old man involving upper extremities, chest, abdomen, and upper back. PMID: 30677796 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 15, 2018 Category: Dermatology Authors: Feng H, Gutierrez D, Rothman L, Meehan S, Sicco KL Tags: Dermatol Online J Source Type: research

Acquired immune deficiency syndrome-related epidemic Kaposi sarcoma.
We present the case of a 42-year-old man with a new diagnosis of HIV and acquired immune deficiency syndrome (AIDS)-related epidemic KS. PMID: 30677797 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 15, 2018 Category: Dermatology Authors: Steuer AB, Cohen JM, Christman MP, Penn LA, Brinster N, Femia AN Tags: Dermatol Online J Source Type: research

Necrobiosis lipoidica.
We present a case of necrobiosis lipoidica (NL) of the right abdomen in a 75-year-old man. A skin biopsy performed showed a layered infiltrate of mono and multinucleated histiocytes palisaded around degenerated collagen bundles. Laboratory workup was unremarkable. The patient was treated with topical corticosteroids with cessation of progression of his disease, although the eruption did not resolve. There are a number of treatments for NL reported in the literature, all with varying efficacy. Although NL lesions are usually asymptomatic, patients with NL must be monitored closely for signs of ulceration or malignant transf...
Source: Dermatol Online J - December 15, 2018 Category: Dermatology Authors: Tong LX, Penn L, Meehan SA, Kim RH Tags: Dermatol Online J Source Type: research

Lymphomatoid papulosis.
We report a case of a 67-year-old man who presented with lymphomatoid papulosis, with necrotic papules that have been intermittently present for over forty years. PMID: 30677799 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 15, 2018 Category: Dermatology Authors: Wiznia LE, Cohen JM, Beasley JM, Meehan SA, Latkowski JM Tags: Dermatol Online J Source Type: research

Botulinum toxin for treatment of Raynaud phenomenon in CREST syndrome.
We present a case of a 75-year-old woman with a longstanding history of CREST syndrome complicated by a digital ulceration and persistent pain associated with recalcitrant Raynaud phenomenon. After failing a number of first-line pharmacologic therapies such as diltiazem, sildenafil, and topical nitropaste, the patient was started on a trial of botulinum toxin for the left second digit, with 10 unit injections into both webspaces for a total of 20 units. Following injection, the patient reported no further baseline pain in the affected finger and an over fifty-percent improvement in discomfort with manipulation of the digit...
Source: Dermatol Online J - December 15, 2018 Category: Dermatology Authors: Berk-Krauss J, Christman MP, Franks A, Sicco KL, Liebman TN Tags: Dermatol Online J Source Type: research

Unusual eruption in association with sorafenib: a case of acquired perforating dermatosis, reactive perforating collagenosis type.
We present a case of acquired perforating dermatosis in a patient with HIV and hepatocellular carcinoma undergoing treatment with sorafenib. PMID: 30677801 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 15, 2018 Category: Dermatology Authors: Lederhandler M, Beasley JM, Brinster NK, Nagler AR Tags: Dermatol Online J Source Type: research

Whitish vulvar tumors associated with macular symmetrical rash.
We present a woman with an unusual case of secondary syphilis after an unnoticed primary infection. She initially presented with multiple grayish plaques and nodules on the vulva associated with an erythematous macular symmetrical rash affecting the trunk and extremities. Despite the increasing incidence of sexually transmitted diseases such as syphilis, presentation with unusual manifestations can lead to a delayed diagnosis. PMID: 30677802 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 15, 2018 Category: Dermatology Authors: Ferrer Guillén B, Giácaman MM, Hernández Bel P, Pérez Ferriols A Tags: Dermatol Online J Source Type: research

Majocchi granuloma on a child's face.
We report a rare case of MG on the face of a six-year-old child caused by Trichophyton mentagrophytes after long term use of topical corticosteroids and other inadequate topical medications. He was treated with griseofulvin 25 mg/kg/day for 35 days unsuccessfully and successful treatment was obtained with terbinafine. PMID: 30677803 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 15, 2018 Category: Dermatology Authors: André NF, Canato M, Zanatta DA, Gomes IF, Abage KT, Carvalho VO Tags: Dermatol Online J Source Type: research

PD-1 inhibitor induced alopecia areata.
We report a case of alopecia areata in a patient on monotherapy with pembrolizumab (PD-1 inhibitor). It is important for the dermatologist to recognize and appropriately treat to decrease morbidity for these patients. PMID: 30677804 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 15, 2018 Category: Dermatology Authors: Guidry J, Brown M, Medina T Tags: Dermatol Online J Source Type: research

Acrodermatitis enteropathica: the need for sustained high dose zinc supplementation.
We describe two male siblings, who presented with evidence of both acute and chronic zinc deficiency, despite being diagnosed with AE very early in life. We wish to highlight the importance of sustained high-dose zinc supplementation and regular monitoring in AE cases. Proper counselling of parents about the need for life long supplementation and increasing requirements with age is essential. PMID: 30677805 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 15, 2018 Category: Dermatology Authors: Ranugha P, Sethi P, Shastry V Tags: Dermatol Online J Source Type: research

Local and distal involution of recalcitrant warts after a single intralesional dose of measles, mumps, and rubella vaccine.
We describe the use of a single intralesional treatment with the measles, mumps, and rubella (MMR) vaccine to successfully eliminate both local and distant recalcitrant warts as well as the proposed mechanism of this method. There are no other known reports of complete wart regression at distant untreated sites after a single intralesional MMR treatment. PMID: 30677806 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 15, 2018 Category: Dermatology Authors: Cantor AS, Hardy CL Tags: Dermatol Online J Source Type: research

Laptop computer-induced hyperpigmentation.
Abstract A 25-year-old afebrile man presented with one year of worsening non-pruritic hyperpigmented non-blanchable reticulated patches and one erosion on his abdomen. He denied trauma, contact with new detergents, and recent travel. He was not taking medications and denied ever having similar skin findings. Further questioning revealed that he positioned his laptop computer directly on his abdomen for several hours every night. His progressive skin findings characterize erythema ab igne, which occurs after repetitive prolonged exposure to temperatures between 43 to 47 degrees Celsius. The hyperpigmentation can oc...
Source: Dermatol Online J - December 15, 2018 Category: Dermatology Authors: Cantor AS, Bartling SJ Tags: Dermatol Online J Source Type: research

The smartphone: an effective tool in transitioning patients from mole mapping to mole excision.
We describe a useful strategy to accurately identify the correct 'atypical' nevus for excision in patients with multiple nevi. We believe this is an effective strategy and eliminates risk of any incorrect procedures being performed, and have used this technique on over 50 patients to date. As the patient stores the images on their own phone, there is no breach of data protection. We find patients prefer this method as opposed to giving others permission to store their sensitive information. PMID: 30677808 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 15, 2018 Category: Dermatology Authors: Kearney L, Kelly JL Tags: Dermatol Online J Source Type: research

Incidence rates of comorbidities among patients with psoriasis in the United States.
Abstract Psoriasis is associated with a substantial burden of comorbidities; however, incidence rates (IRs) of these comorbidities following psoriasis diagnosis are not well characterized. Using administrative claims data from the Truven Health Analytics MarketScan Commercial and Medicare Supplemental Databases between January 1, 2002 and September 30, 2015, we compared the incidence of newly diagnosed comorbidities among patients with psoriasis versus demographically matched (birth year, gender, and geographic region) control patients without psoriasis in the United States. Comorbidities of interest were identifi...
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Feldman SR, Hur P, Zhao Y, Tian H, Wei Z, Wang X, Herrera V Tags: Dermatol Online J Source Type: research

Dermatology on Flickr.
Abstract Flickr, which was launched in 2004, is one of the oldest photo-sharing services online. The company, which was once at the forefront of the internet social media explosion, lost users and received criticism as its repeated acquisitions by other companies forced users to adapt to new owners. Now facing another acquisition by the online photo-sharing service SmugMug, the future is uncertain again for the once popular internet and mobile application service. Flickr, with its rapid rise in popularity, sudden halt in growth, and its gradual loss of users and popularity, has been repeatedly looked to as a lesso...
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Kuschel S, Patel RR, Dellavalle RP Tags: Dermatol Online J Source Type: research

Recurrent retroauricular cystic nodules: lichen planus follicularis tumidus.
We present a case of a 67-year-old man with clinical and histopathologic findings consistent with LPFT and discuss differential diagnostic considerations for entities resembling LPFT. Lastly, treatment options for LPFT are reviewed. PMID: 30677811 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Chau T, Amini N, Eisen DB, Fung MA Tags: Dermatol Online J Source Type: research

Cutaneous mucinosis of infancy: report of a rare case and review of the literature.
We report a case of CMI and review the prior 13 cases in the literature. The patient was a 5-year-old girl who presented with asymptomatic dermal papules and plaques on her leg and back with no overlying color change. These lesions were first noticed during infancy and had become slightly more evident over time. The patient had a history of birthmarks and eczema. Her family history included eczema, allergies, photosensitivity, and Graves disease. Pre-biopsy clinical differential diagnosis included connective tissue nevus, granuloma annulare, myofibroma, lipofibroma, and lymphangioma. Biopsies revealed significant increase ...
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Chan C, Mann JA, Jr MCM, Yan S, Momtahen S Tags: Dermatol Online J Source Type: research

A case report of adult-onset multiple angiokeratomas with zosteriform distribution.
We report an unusual case of multiple angiokeratomas in a zosteriform distribution with onset at age 74. PMID: 30677813 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Grewal AK, Chambers CJ, Silverstein M Tags: Dermatol Online J Source Type: research

Polycyclic annular presentation of pemphigus vulgaris with an eosinophil predominance in two pregnant patients.
P, Kılıç S Abstract Pemphigus during pregnancy has a more complicated course owing to the limitations in treatment options and alterations in the severity and presentation of the clinical features. We would like to present two pemphigus vulgaris (PV) cases associated with pregnancy with an unusual clinical appearance exhibiting polycyclic, annular, vesiculobullous plaques with marked eosinophil infiltration in histopathology. To the best of our knowledge pregnancy-associated pemphigus cases with this particular clinical presentation have not been reported in the literature. Changes in the immunologic and ...
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Küçükoğlu R, Sun GP, Kılıç S Tags: Dermatol Online J Source Type: research

A novel case of NKX3.1-positive metastatic cutaneous prostate cancer.
We present an 87-year-old man previously diagnosed with prostate cancer treated with brachytherapy, who presented with a metastatic prostate adenocarcinoma of the scalp mimicking a basal cell carcinoma. Herein, we present a patient with an NKX 3.1 positive cutaneous metastatic prostate carcinoma identified through NKX3.1 stain rather than the typical PSA/PSAP stain. PMID: 30677815 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Wong JK, Minni JP, Nowak MA Tags: Dermatol Online J Source Type: research

Basal cell carcinoma with intravascular invasion: A case report and review of the literature.
We report a case of an infiltrative BCC on the scalp that showed evidence of both intravascular and perineural invasion. The tumor locally recurred in the bone marrow space 4.5 years following the initial procedure. Since recurrence and metastasis of BCC can be delayed for many years, we recommend long term follow-up for tumors showing aggressive features. PMID: 30677816 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Mazloom S, Rich M, Grider D, Phillips M Tags: Dermatol Online J Source Type: research

Leukocytoclastic vasculitis with late-onset Henoch-Sch önlein purpura after trifluridine/tipiracil treatment.
We present a case of trifluridine/tipiracil-induced leukocytoclastic vasculitis (LCV) with late-onset Henoch-Schönlein purpura (HSP) in a 42-year-old man with metastatic appendiceal cancer. The patient's biopsy-proven LCV developed one month after he began trifluridine/tipiracil treatment and resolved after discontinuation of the drug. He presented to the emergency department two months after the appearance of his LCV with shortness of breath, elevated blood pressure, elevated creatinine, hematuria, and proteinuria. A kidney biopsy was performed and the presence of IgA deposits and cellular crescents indicated rapidly...
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Aria AB, Chen L, Glass WF, Lahoti A, Chon SY Tags: Dermatol Online J Source Type: research

Erythema annulare centrifugum-type eruption in a patient undergoing cancer vaccine immunotherapy.
We report a patient developing an immune related adverse effect from sipuleucel-T drug-induced erythema annulare centrifugum-like eruption. A brief review of the mechanism and implications of this eruption are also included. PMID: 30677818 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Tadros J, Rahnama-Moghadam S Tags: Dermatol Online J Source Type: research

Glomuvenous malformations in a young man.
Abstract A young man presented with blue nodules on the trunk, face, and extremities that gradually increased in number and size. His mother had similar lesions. Initially, blue rubber bleb nevus syndrome was suspected, but histological findings confirmed the diagnosis of hereditary glomuvenous malformations. Making the correct diagnosis spares the patient unnecessary evaluation for the arteriovenous malformations of the gastrointestinal tract associated with the former diagnosis. PMID: 30677819 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Abbas A, Braswell M, Bernieh A, Brodell RT Tags: Dermatol Online J Source Type: research

Eosinophilic pustular folliculitis with labial and oral involvement: report of a rare presentation.
Abstract Eosinophilic pustular folliculitis (EPF) is a recurrent inflammatory dermatosis primarily involving hair follicles. Several subtypes of EPF have been described: Classic EPF, infantile EPF, and immunosuppression-associated EPF. Although classic EPF has a predilection for face, involvement of hairless areas such as palms and soles has been reported frequently. There are rare case reports of mucosal EPF. Herein, we report a woman who presented with classic EPF involving the lip and oral mucosa. PMID: 30677820 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Sepaskhah M, Ahramian Pour N, Godarzi H, Sari Aslani F, Jowkar F Tags: Dermatol Online J Source Type: research

Acneiform eruption induced by vedolizumab.
We report a case of severe acneiform eruption induced by vedolizumab in a 17-year-old woman with ulcerative colitis. PMID: 30677821 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Magdaleno-Tapial J, Ferrer-Guillén B, Valenzuela-Oñate C, Esteve-Martínez A Tags: Dermatol Online J Source Type: research

Role of family history in patchy alopecia areata.
CONCLUSION: Patchy alopecia patients with a family history of alopecia areata experienced worse outcomes. Concomitant autoimmunity may also adversely affect alopecia areata disease course. Identification of a positive family history of alopecia areata and control of autoimmune comorbidities may aid alopecia areata management. PMID: 30677822 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Wang S, Ratnaparkhi R, Piliang M, Bergfeld WF Tags: Dermatol Online J Source Type: research

Augmenting the scope of dermatologic care and training via student-run health clinics.
Abstract Skin cancer is a major public health problem. Unfortunately, individuals who lack health insurance have lower skin cancer screening rates compared to insured individual and, therefore, have a higher risk of more advanced cancer diagnoses. Student-run health clinics may be the answer to this dilemma. Student-run health clinics can not only help by providing essential dermatologic services to the general population, both insured and uninsured, but also provide early exposure to dermatology education for medical students. PMID: 30677823 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Kamath P, Stratman S, Agarwal N Tags: Dermatol Online J Source Type: research

Infantile hemangiomas: our current understanding and treatment options.
Abstract Infantile hemangioma (IH) is the most common vascular tumor of infancy, affecting up to 10% of all infants. Our understanding of IH and its management has greatly evolved. The etiology of IH is unclear but hypoxia is thought to play a key role. Furthermore, GLUT1, IGF2, and HIF-1-? are thought to be important mediators. Current management options include active observation, medical treatment, and surgical intervention. The goals of treatment are preventing cosmetic disfiguration, psychosocial distress, and life-threatening complications. Infantile hemangioma should be managed with an individual, patient-c...
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Soliman YS, Khachemoune A Tags: Dermatol Online J Source Type: research

Psoriasis therapy and aortic inflammation - translating statistical to clinical significance.
Abstract Psoriasis patients are known to have comorbid aortic vascular inflammation, which is one of the leading causes of cardiovascular morbidity and mortality in this population. Many studies report statistically significant improvements in aortic vascular inflammation after use of tumor necrosis factor inhibitors or interleukin-12/23 antagonists. However, the clinical significance in reduction of adverse cardiovascular events in psoriatic patients owing to biologic therapy has not been examined. Regardless of clinically significant cardiovascular benefits, dermatologists should continue to treat psoriasis pati...
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Kazemi A, Cline A, Cardwell LA, Feldman SR Tags: Dermatol Online J Source Type: research

Genital Rejuvenation: The Next Frontier in Medical and Cosmetic Dermatology.
Abstract Genital rejuvenation encompasses not only the nonsurgical interventions but also the surgical procedures that are utilized to improve the functional aspects and/or enhance the aesthetic presentation of the genitalia of women (vaginal rejuvenation) and men (scrotal rejuvenation). Vaginal rejuvenation was introduced into the medical literature in 2007; yet, within the last decade, physician and patient interest in this field has markedly increased. In contrast, the term scrotal rejuvenation was only coined in 2018. Rejuvenation of the genitalia may be considered for hair-associated (alopecia and hypertricho...
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Cohen PR Tags: Dermatol Online J Source Type: research