Decreased phototherapy effectiveness on lower body.
Abstract Although phototherapy is an effective treatment for many dermatological conditions on the face, trunk, and proximal extremities, a common issue plaguing whole-body phototherapy is its diminished efficacy on the legs. In this commentary, we elaborate on the factors underlying this phenomenon, as well as potential solutions to improve treatment success. PMID: 31329386 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 15, 2019 Category: Dermatology Authors: Piccinin MA, Cline A, Feldman SR Tags: Dermatol Online J Source Type: research

Variable potential for social media platforms in raising skin cancer awareness.
Abstract Social media plays an important role in public health outreach, given its ability to connect virtual communities. Examples include campaigns for smoking cessation, breast cancer awareness, and emergency relief [1]. Few studies have investigated the utility of social media in skin cancer awareness, though the potential has been demonstrated [2]. We sought to evaluate current differential social media platform use in skin cancer awareness. PMID: 31329387 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 15, 2019 Category: Dermatology Authors: Jhawar N, Lipoff JB Tags: Dermatol Online J Source Type: research

Discordant molecular tests for acute Graft-Versus-Host Disease after liver transplant: FISHing for the proper diagnosis.
We report cutaneous fluorescent in-situ hybridization (FISH) analysis as a useful test for earlier diagnostic confirmation in a case of acute graft-versus-host disease (GVHD) in a sex-mismatched liver transplant patient compared to the gold standard peripheral blood short tandem repeat chimerism analysis. PMID: 31329388 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 15, 2019 Category: Dermatology Authors: Evans JB, Shearer SM, Zhao WJ, Jones D, Kaffenberger BH Tags: Dermatol Online J Source Type: research

Apocrine adenocarcinoma in the setting of apocrine hidrocystoma of the leg.
We present the case of a 48-year-old man with a history of total body irradiation for chronic myelocytic leukemia, diabetes mellitus, and obesity who presented with a calf mass of two years' duration. Epidermal inclusion cyst was presumed and excisional biopsy was carried out. Pathologic analysis revealed apocrine adenocarcinoma in the setting of a precursor apocrine hidrocystoma. Our patient's unique altered immunity and the direct effects of irradiation on the local microenvironment may have resulted in his rare presentation of co-occurrence of apocrine adenocarcinoma within an existing apocrine hidrocystoma. To our know...
Source: Dermatol Online J - June 15, 2019 Category: Dermatology Authors: Toyoda Y, Franck P, Brownstone ND, Lieberman M, Magro CM, Otterburn DM Tags: Dermatol Online J Source Type: research

Amyloidosis cutis dyschromica: report of 3 cases.
We present three patients who presented with generalized hyper- and hypopigmented patches, sparing face, hands, and feet in all three cases. The presence of amorphous eosinophilic deposits in the papillary dermis confirmed the diagnosis of ACD; the deposits were stained by crystal violet in the histopathological examination of the lesions. In all three cases, similar lesions were present in some of the family members. ACD should be considered in the differential diagnosis of diffuse hyperpigmentation studded with hypopigmentation, especially when beginning in childhood. PMID: 31329390 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 15, 2019 Category: Dermatology Authors: Sepaskhah M, Taghipour K, Miri A, Dastgheib L, Sari Aslani F Tags: Dermatol Online J Source Type: research

Bullous acral eruption related to secukinumab.
Abstract Skin reactions related to secukinumab are uncommon. Although the initial phase 3 studies of this medication reported infection and urticaria as adverse cutaneous events, other cases of unique adverse events have since been reported. We are presenting a patient who developed an exuberant hand and foot reaction after starting secukinumab. PMID: 31329391 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 15, 2019 Category: Dermatology Authors: Blackcloud P, Dupuy E, Kang Y, Smart C, Hsiao J Tags: Dermatol Online J Source Type: research

Circle hair: report of two cases and brief review of the literature.
n C Abstract Circle hair (CH) is an interesting subtype of ingrown hair, characterized by the growing of hair shaft in a spiral or circular morphology underneath a translucent layer of stratum corneum, parallel to skin surface. In contrast to rolled hair (RH), neither perifollicular inflammation nor abnormal follicular keratinization are known to accompany CH. The reason why the hair shaft grows circumferentially and transversely under the skin instead of emerging through an apparently open hair follicle ostium and growing vertically remains to be determined. Although CH is a frequent benign incidental finding in ...
Source: Dermatol Online J - June 15, 2019 Category: Dermatology Authors: Durmaz EÖ, Demirkesen C Tags: Dermatol Online J Source Type: research

Low-dose naltrexone: a unique treatment for amyopathic dermatomyositis.
Abstract Gottron papules, a heliotrope rash, scalp and extremity erythema, pruritus, and fatigue are the characteristic signs and symptoms of amyopathic dermatomyositis (ADM). Amyopathic dermatomyositis is considered a distinct entity from dermatomyositis (DM) because the characteristic muscle weakness and muscle enzyme elevations of DM are absent in ADM. With respects to treatment, ADM treatments have traditionally included topical corticosteroids and/or systemic immunosuppressants and immunomodulators. Herein we present a patient with refractory ADM that was responsive to low-dose naltrexone therapy. PMID: ...
Source: Dermatol Online J - June 15, 2019 Category: Dermatology Authors: Manudhane AP, Schrom KP, Ezaldein HH, Armile JA Tags: Dermatol Online J Source Type: research

Bullous leukemia cutis: a rare clinical subtype.
Abstract Leukemia cutis represents infiltration of the skin by malignant leukocytes and typically presents as firm, red-brown papules and nodules. The bullous clinical subtype is considered a rare entity and can be a diagnostic challenge. This case describes a patient with bullous leukemia cutis mimicking vesiculobullous skin disease. PMID: 31329394 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 15, 2019 Category: Dermatology Authors: Sandre M, Osmond A, Ghazarian D, Ghiasi N Tags: Dermatol Online J Source Type: research

Warfarin-induced skin necrosis within psoriatic plaques.
Abstract A myriad of different phenomena exist in the dermatological literature which are based on the concept of locus minores resistentiae. The most commonly described phenomenon is the Koebner phenomenon, which is classically associated with the emergence of psoriatic lesions post trauma. Warfarin-induced skin necrosis (WISN) is a rare but severe side effect that leads to necrosis of the skin, predominantly on areas with increased subcutaneous fat. The presented case reports on WISN within psoriatic plaques. PMID: 31329395 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 15, 2019 Category: Dermatology Authors: Eichhoff G Tags: Dermatol Online J Source Type: research

Hidradenitis suppurativa associated with sorafenib initiation.
We report the development of hidradenitis suppurativa (HS) in a patient after initiation of treatment with sorafenib. HS is marked by recurrent deep painful nodules, fluctuant abscesses, and draining sinus tracts most frequently occurring in the groin and axilla. To our knowledge, sorafenib-induced HS in the axillary and inguinal skin folds has not been previously reported. PMID: 31329396 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 15, 2019 Category: Dermatology Authors: Morse DC, Chockalingam R, Pye A, Huen A Tags: Dermatol Online J Source Type: research

Carcinosarcoma of the hand.
Abstract Carcinosarcomas are rare malignant tumors derived of both epithelial and mesenchymal elements. Herein, we report an elderly man originally diagnosed with a squamous cell carcinoma of the hand. Upon excision, the tumor was found to be a more aggressive carcinosarcoma. Immunohistochemical stains revealed that the sarcoma component of the lesion was vimentin positive, whereas the primary carcinoma tumor cells were positive for p63 and CK903. Both components were negative for CD34 and D2-40. This tumor was found to have angiolymphatic invasion and eventually metastasized to the axillary lymph nodes and lungs....
Source: Dermatol Online J - June 15, 2019 Category: Dermatology Authors: Gamret AC, Fertig RM, Klingbeil KD, Satahoo S, Kerr DA, Romanelli P, Miteva M, Rodgers SE Tags: Dermatol Online J Source Type: research

Comment on "Botulinum toxin type-A as an alternative treatment for gummy smile: a case report".
Comment on "Botulinum toxin type-A as an alternative treatment for gummy smile: a case report". Dermatol Online J. 2019 Jun 15;25(6): Authors: Pedron IG Abstract Currently, the search for esthetic excellence has become the main objective in the facial treatment. The gummy smile is one of the complaints from the patients, since this situation may influence their self-esteem and social relationship. The development of new techniques, such as the application of botulinum toxin, may be a conservative therapeutic option in the treatment of gummy smile. The purpose of this letter is to comment som...
Source: Dermatol Online J - June 15, 2019 Category: Dermatology Authors: Pedron IG Tags: Dermatol Online J Source Type: research

Corrigendum: Impact on clinical practice of a non-invasive gene expression melanoma rule-out test: 12-month followup of negative test results and utility data from a large US registry study.
Abstract The revised version of the article corrected Figure 2. This change appears in the revised online PDF copy of this article. PMID: 31329399 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 6, 2019 Category: Dermatology Authors: Ferris LK, Rigel DS, Siegel DM, Skelsey MK, Peck GL, Hren C, Gorman C, Frumento T, Jansen B, Yao Z, Rock J, Knezevich SR, Cockerell CJ Tags: Dermatol Online J Source Type: research

Ashy dermatosis: a review.
Abstract Ashy dermatosis is characterized by asymptomatic, symmetrically-distributed, gray-colored macules located on the trunk, neck, face, and upper extremities. The condition occurs most commonly in patients with Fitzpatrick phototype III-V skin. The etiology is unknown, but drug ingestion, infection, and genetic factors have been suggested to elicit ashy dermatosis. No gold standard treatments have been established yet. The most successful treatment to date has been clofazimine, although topical tacrolimus, oral dapsone, narrowband ultraviolet light B phototherapy, and isotretinoin have shown treatment success...
Source: Dermatol Online J - May 15, 2019 Category: Dermatology Authors: Nguyen K, Khachemoune A Tags: Dermatol Online J Source Type: research

Impact on clinical practice of a non-invasive gene expression melanoma rule-out test: 12-month follow-up of negative test results and utility data from a large US registry study.
Abstract The Pigmented Lesion Assay (PLA, sensitivity 91-95%, specificity 69-91%, negative predictive value ?99%) is a commercially available, non-invasive gene expression test that helps dermatologists guide pigmented lesion management decisions and rule out melanoma. Earlier studies have demonstrated high clinical utility and no missed melanomas in a 3-6-month follow-up period. We undertook the current investigations to provide 12-month follow-up data on PLA(-) tests, and to further confirm utility. A 12-month chart review follow-up of 734 pigmented lesions that had negative PLA results from 5 US dermatology cen...
Source: Dermatol Online J - May 15, 2019 Category: Dermatology Authors: Ferris LK, Rigel DS, Siegel DM, Skelsey MK, Peck GL, Hren C, Gorman C, Frumento T, Jansen B, Yao Z, Rock J, Knezevich SR, Cockerell CJ Tags: Dermatol Online J Source Type: research

Comparison of quality of life and illness perception among patients with acne, eczema, and psoriasis.
Abstract Dermatologic diseases have a similar influence on quality of life (QoL) and disability as other chronic medical conditions. Although QoL has been studied in relation to acne, eczema, and psoriasis, there is little information on how patients conceptualize their diseases - the illness experience. More information about illness perception (IP) and the impact of these perceptions on QoL, will help clinicians identify and address patients' conceptions, with the potential to positively impact patients' wellbeing. We sought to examine the effect of IP on QoL and make comparisons across acne, psoriasis, and ecze...
Source: Dermatol Online J - May 15, 2019 Category: Dermatology Authors: Nagpal N, Gordon-Elliott J, Lipner S Tags: Dermatol Online J Source Type: research

Interview date trends for dermatology residency from 2012-2017.
Abstract Data regarding dermatology residency interview patterns can better inform applicants regarding the application process as well as encourage further coordination among programs. Our objective was to describe dermatology residency interview date patterns over the past five applications cycles from 2012 to 2017. A retrospective review of dermatology online forums (the Dermatology Interest Group Association and Student Doctor Network) was performed from 2012 to 2017; these web-based public databases were reviewed for interview dates and interview offer dates. Data from 117 programs per year were obtained. The...
Source: Dermatol Online J - May 15, 2019 Category: Dermatology Authors: Kwon CD, Liao RS, Young PJ, Lee AH, Zuo RC, Yi PH, Grossberg AL Tags: Dermatol Online J Source Type: research

Topical probiotics: the unknowns behind their rising popularity.
CONCLUSION: With increasing popularity among the general public, but insufficient clinical data to demonstrate large-scale effectiveness and a thorough understanding of side effects, there is a need for further mechanistic and clinical investigation, as well as improved regulation and standardization of topical probiotic products. PMID: 31220895 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - May 15, 2019 Category: Dermatology Authors: Lee GR, Maarouf M, Hendricks AJ, Lee DE, Shi VY Tags: Dermatol Online J Source Type: research

Treatment of warts with topical cidofovir in a pediatric patient.
Abstract Cidofovir is an antiviral nucleotide analogue with relatively new treatment capacities for dermatological conditions, specifically verruca vulgaris caused by human papilloma virus infection. In a 10-year old boy with severe verruca vulgaris recalcitrant to multiple therapies, topical 1% cidofovir applied daily for eight weeks proved to be an effective treatment with no adverse side effects. This case report, in conjunction with multiple published reports, suggests that topical 1% cidofovir is a safe and effective treatment for viral warts in pediatric patients. PMID: 31220896 [PubMed - in process] (S...
Source: Dermatol Online J - May 15, 2019 Category: Dermatology Authors: Nickles MA, Sergeyenko A, Bain M Tags: Dermatol Online J Source Type: research

Apocrine adenocarcinoma of the eyelid: case report and literature review on management.
We report the case of a 58-year-old woman with apocrine adenocarcinoma located on her left upper eyelid. Excisional biopsy demonstrated focal apocrine secretion in a basaloid nest proliferation. The patient had no recurrence at four months. Our case provides insight into the workup and management of eyelid apocrine adenocarcinoma. Furthermore, we discuss key management recommendations according to previous authors' experiences with eyelid apocrine adenocarcinoma. PMID: 31220897 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - May 15, 2019 Category: Dermatology Authors: Rosales Santillan M, Tschen JA, Soparkar CN Tags: Dermatol Online J Source Type: research

Prurigo pigmentosa following laparoscopic gastric sleeve.
Abstract Prurigo pigmentosa is an uncommon inflammatory skin disease predominately affecting young women. Clinically the disease presents with erythematous and urticarial papules arranged in a reticular pattern. Lesions heal with reticulated hyperpigmentation. Strict ketogenic diet is one of many factors that might trigger the disease. In this article, we present a case of prurigo pigmentosa following a complicated laparoscopic gastric sleeve with the resolution of the rash after improvement of the patient's diet. PMID: 31220898 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - May 15, 2019 Category: Dermatology Authors: Al-Dawsari NA, Al-Essa A, Shahab R, Raslan W Tags: Dermatol Online J Source Type: research

Factitial panniculitis as a manifestation of self-imposed factitious disorder.
Abstract Factitious disorder imposed on self is characterized by self-induction. Dermatitis artefacta, the cutaneous subtype of factitious disorder imposed on self, can have a variety of atypical presentations. A 36-year-old woman with an extensive past medical history presented with painful nodules on her abdomen, thighs, and arms. Histologic evaluation identified panniculitis with foreign body material seen under polarization. Chart review from previous hospital visits established a history of factitious disorder imposed on self and upon subsequent search of the hospital room, syringes with an unknown substance ...
Source: Dermatol Online J - May 15, 2019 Category: Dermatology Authors: Yanes AF, Owen JL, Colavincenzo ML Tags: Dermatol Online J Source Type: research

Late-onset pseudoepitheliomatous hyperplasia developing within a red ink tattoo.
Abstract The popularity of tattoos has increased dramatically worldwide particularly in the last three decades, giving rise to the frequent occurrence of a wide spectrum of secondary cutaneous and systemic complications. Pseudoepitheliomatous hyperplasia (PEH) is a benign irregular hyperplasia of the epidermis occurring in response to various stimuli, that clinically and histopathologically resembles cutaneous neoplasms such as squamous cell carcinoma and keratoacanthoma. In an attempt to improve the awareness of the possible occurrence of PEH in tattoos and of its diagnostic and therapeutic aspects, we present he...
Source: Dermatol Online J - May 15, 2019 Category: Dermatology Authors: Badavanis G, Constantinou P, Pasmatzi E, Monastirli A, Tsambaos D Tags: Dermatol Online J Source Type: research

Keratosis lichenoides chronica: First case reported in Chile.
We present a woman with a history of years of evolution of confluent hyperkeratotic papules and plaques with a generalized linear and reticulate pattern. Histopathological characteristics concordant with keratosis lichenoides chronica were finally evidenced after several non-specific biopsies. The cutaneous manifestations, chronicity. histopathology findings, and refractoriness to therapies are typical of this rare dermatosis. PMID: 31220901 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - May 15, 2019 Category: Dermatology Authors: Escanilla C, Truffello D, Cevallos C, Arellano R, Del-Río M, Villarroel J, Chávez F Tags: Dermatol Online J Source Type: research

Multiple eruptive dermatofibromas associated with pregnancy- a case and literature review.
ipe P Abstract Dermatofibromas are common and asymptomatic benign histiocytic tumors. The occurrence in a small number (up to 5 lesions) is frequent. However, the expression "multiple eruptive dermatofibromas" is reserved for the appearance of more than 5 lesions in less than four months. Multiple eruptive dermatofibromas are rare and usually associated with an underlying systemic condition, the most common being autoimmune diseases or HIV infection. Herein we report multiple eruptive dermatofibromas developing in an otherwise healthy pregnant woman. Although the pathogenesis of this condition remains un...
Source: Dermatol Online J - May 15, 2019 Category: Dermatology Authors: Queirós C, Uva L, Soares de Almeida L, Filipe P Tags: Dermatol Online J Source Type: research

Indurated purple plaques on the scalp.
We describe a 75-year-old man who presented with three tender, indurated violaceous plaques on his scalp. Biopsy revealed a poorly circumscribed infiltrate extending into the subcutaneous fat, composed of atypical epithelioid cells lining vascular spaces. We provide a brief review of the clinical presentation, histopathologic features, differential diagnosis, and management of this rare tumor. PMID: 31220903 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - May 15, 2019 Category: Dermatology Authors: Tung JK, Korman JB, Yasuda MR Tags: Dermatol Online J Source Type: research

Novel PTEN mutation in Cowden syndrome: case report with late diagnosis and non-malignant course.
We present a case of Cowden syndrome with late diagnosis presenting with a florid dermatological expression and multiple benign tumors, but no malignancies. A novel PTEN mutation was identified. PMID: 31220904 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - May 15, 2019 Category: Dermatology Authors: Martínez-Doménech A, García-Legaz Martínez M, Magdaleno-Tapial J, Pérez-Pastor G, Rodríguez-López R, Pérez-Ferriols A Tags: Dermatol Online J Source Type: research

A fleshy papule on the eyelid.
We report an instance of angiolymphoid hyperplasia with eosinophilia involving the eyelid in a 19-year-old woman with review of literature. PMID: 31220905 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - May 15, 2019 Category: Dermatology Authors: Adya KA, Inamadar AC, Palit A Tags: Dermatol Online J Source Type: research

Wound healing elective: an opportunity to improve medical education curriculum to better manage the increasing burden of chronic wounds.
Abstract Chronic wounds are highly prevalent and have become a public health crisis. Successful treatment of chronic wounds requires that healthcare providers study both the pathophysiology of wound healing and maintain knowledge of the most current wound care guidelines set forth by the Agency for Healthcare Research and Quality. Unfortunately, medical students currently receive limited wound care training. A focused and well-organized course integrating a diverse group of medical and surgical faculty, residents, and medical students in the clinical years has been created to address this growing medical issue. Th...
Source: Dermatol Online J - May 15, 2019 Category: Dermatology Authors: Kamath P, Agarwal N, Salgado CJ, Kirsner R Tags: Dermatol Online J Source Type: research

Extramammary Paget disease.
Abstract In 1874, Sir James Paget first described Paget disease of the nipple, also known as mammary Paget disease. In 1889, extramammary Paget disease (EMPD) of the scrotum and penis was identified. Although mammary and extramammary Paget disease are both characterized by epidermal Paget cells and share a similar clinical presentation, their uniqueness lies in anatomical location and histogenesis. EMPD presents as an erythematous plaque on apocrine gland bearing areas (i.e. vulva, perineum, perianal region, scrotum, and penis) in older men and women. It can be a focal, multifocal, or an ectopic process. Immunohis...
Source: Dermatol Online J - April 15, 2019 Category: Dermatology Authors: St Claire K, Hoover A, Ashack K, Khachemoune A Tags: Dermatol Online J Source Type: research

Healthcare and dermatology on WeChat.
Abstract WeChat is a closed social networking platform that allows users to connect privately, providing instant text, photo sharing, voice, and video calls. It is now the most popular mobile chat app in China. The widespread use and ease of establishing technology made WeChat an ideal platform for healthcare, in which it has many uses that include scheduling, follow up, and post-procedure monitoring. In addition, one may make payments and handle prescriptions via e-pharmacy. Dermatologists are often looking for a secure and easy way to use mobile applications to share clinical images and to obtain photographs fro...
Source: Dermatol Online J - April 15, 2019 Category: Dermatology Authors: Maymone MB, Du T, Dellavalle RP Tags: Dermatol Online J Source Type: research

Oral lichen sclerosus: a rare case and update.
z LMG Abstract Lichen sclerosus (LS) is a chronic inflammatory mucocutaneous disease that often affects the anogenital area; oral mucosal lesions are extremely rare. A 52-year-old woman presented for evaluation of an 8-year history of a persistent whitish plaque in the buccal mucosa. Intraoral examination revealed multiple elevated whitish plaques diffusely distributed in the buccal mucosa associated with an area of tissue atrophy. Although both leukoplakia and lichen planus were considered, incisional biopsy and later, full excision confirmed the histopathological diagnosis of oral LS. After 6 months of follow-up...
Source: Dermatol Online J - April 15, 2019 Category: Dermatology Authors: Gonçalo RIC, Vargas YDCM, Medeiros HCM, Xerez MC, Santos HBP, Queiroz LMG Tags: Dermatol Online J Source Type: research

Incisional biopsy critical in obtaining definitive diagnosis in a clinically challenging case.
We present a case of a 70-year-old man with hidradenocarcinoma of the left chin, a diagnosis that was delayed owing to repeated superficial biopsies that were negative for disease. Diagnosis was ultimately obtained via an incisional biopsy. We discuss the clinical features of hidradenocarcinoma and why this diagnosis can be easily missed with superficial biopsies. It is important that dermatologists consider incisional biopsies in the workup of clinically challenging lesions for which malignancy is considered. PMID: 31046907 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 15, 2019 Category: Dermatology Authors: Fernandez J, Ren V, Cohen D, Shimizu I Tags: Dermatol Online J Source Type: research

Darier disease with disseminated herpes simplex virus type 2 infection.
Abstract Darier disease (DD), also known as keratosis follicularis or Darier-White disease, is a rare autosomal dominant genodermatosis that presents as hyperkeratotic, warty papules affecting the seborrheic and intertriginous areas. Patients with DD are at risk of secondary infections including the rare complication of Kaposi varicelliform eruption (KVE), a widespread viral infection most commonly caused by herpes simplex virus (HSV). Darier disease with secondary KVE can lead to widespread systemic infection and death. This case report discusses an individual with DD who subsequently developed KVE due to dissemi...
Source: Dermatol Online J - April 15, 2019 Category: Dermatology Authors: Walker K, Martini A, Philips H, Sharp L, Thomas K, Tarbox M Tags: Dermatol Online J Source Type: research

Multiple acantholytic dyskeratotic acanthomas in a liver-transplant recipient.
We present here a new case of this rare lesion that developed in a liver-transplant patient and review the salient features of this uncommon condition. PMID: 31046909 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 15, 2019 Category: Dermatology Authors: Kanitakis J, Gouillon L, Jullien D, Ducroux E Tags: Dermatol Online J Source Type: research

Late-onset amyloidosis cutis dyschromica: an unusual case.
u G, Ekşioğlu M Abstract Amyloidosis cutis dyschromica (ACD) is a rare form of primary cutaneous amyloidosis. ACD, first described by Morishima in 1970 is characterized by (i) macular, speckled, reticular hyperpigmentation with hypopigmented spots distributed extensively over the body; (ii) little or no pruritus; (iii) prepubertal onset; and (iv) focal subepidermal amyloid deposition. A 49-year-old woman presented with a 20-year history of progressive, asymptomatic, generalized mottled hyper- and hypopigmented macules all over the body. Histopathological examination of a punch biopsy specimen showed deposition o...
Source: Dermatol Online J - April 15, 2019 Category: Dermatology Authors: Kutlu Ö, Çetinkaya PÖ, Ünverdi H, Vahapoğlu G, Ekşioğlu M Tags: Dermatol Online J Source Type: research

Endogenous ochronosis: when clinical suspicion prevails over histopathology.
We report a new case of EO with cutaneous and joint involvement, in which a high clinical suspicion, confirmed by elevated AHG in urine was the key in the diagnosis. PMID: 31046911 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 15, 2019 Category: Dermatology Authors: Sánchez-Martínez EM, García-Briz MI, Moneva-Léniz LM, Gegúndez-Hernández H, Pose-Lapausa P, Mateu-Puchades A Tags: Dermatol Online J Source Type: research

Molluscum contagiosum with dermoscopic features in an unusual areola and nipple location.
Abstract Molluscum contagiosum is a common, contagious viral skin disease that often affects children and adolescents. Involvement of the areola and nipple are rarely reported. Herein we report two young women with molluscum contagiosum on the areola-nipple complex and we discuss the dermoscopic features of the lesions at this unusual site. PMID: 31046912 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 15, 2019 Category: Dermatology Authors: Demirdag HG, Ayanoglu BT, Durmus B, Bulut M, Akay BN Tags: Dermatol Online J Source Type: research

Morphea secondary to interferon beta1b injection: a case and review of the literature.
Abstract Interferon beta (IFNβ) is a drug used successfully in the treatment of multiple sclerosis (MS). Although IFNβ is a safe and well-tolerated drug, dermatological side effects are common. The most common dermatological adverse effect is a local reaction at the injection site. It may also cause inflammatory and immune-mediated dermatological side effects. However, morphea induced by IFNβ1b injection is very rare. PMID: 31046913 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 15, 2019 Category: Dermatology Authors: Ozlu E, Karadag AS, Akdeniz N, Uzuncakmak TK, Zemheri E, Ozkanli S Tags: Dermatol Online J Source Type: research

Allergic contact dermatitis related to homemade slime: a case and review of the literature.
We present a case of a child with hand dermatitis, history of exposure to slime, and positive allergen patch testing to two ingredients found in slime. The case underscores the need for clinicians to be aware of slime as a possible cause of allergic contact dermatitis in children. Given the trend of newly-reported cases, we briefly review the current literature to date. PMID: 31046914 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 15, 2019 Category: Dermatology Authors: Mainwaring W, Zhao J, Hunt R Tags: Dermatol Online J Source Type: research

Exogenous ochronosis: the failure of depigmenting creams.
We present a woman who developed EO on the face, upper chest, and back after prolonged use of a depigmenting cream containing hydroquinone. PMID: 31046915 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 15, 2019 Category: Dermatology Authors: Sánchez-Martínez EM, García-Briz MI, Moneva-Léniz LM, Gegúndez-Hernández H, Pose-Lapausa P, Mateu-Puchades A Tags: Dermatol Online J Source Type: research

Melanoma patient notification and treatment timelines.
Abstract Melanoma is an extremely aggressive cancer for which the American Academy of Dermatology currently does not have formal recommendations outlining a timeline from biopsy to definitive treatment. Our dermatology department investigated our treatment timeline for melanoma. Using the database from our electronic medical record, Epic, we evaluated patients over a one-year period; in total we identified 109 melanomas. We evaluated patient demographics, tumor characteristics, and timelines regarding diagnosis and treatments. There was a statistically significant difference in patient notification of diagnosis an...
Source: Dermatol Online J - April 15, 2019 Category: Dermatology Authors: Niehues NB, Evanson B, Smith WA, Fiore CT, Parekh P Tags: Dermatol Online J Source Type: research

Paradoxical reversed plantar involvement during ixekizumab therapy for psoriasis.
We present a patient with palmoplantar psoriasis treated with ixekizumab who achieved a favorable response that was coupled with a rare paradoxical reaction, reversed plantar involvement. The reason for this phenomenon and its clinical course are uncertain, but these new lesions are proving recalcitrant to complementary therapies. Provided the increasingly widespread use of biologic therapies, the incidence and diversity of paradoxical reactions are expected to increase. PMID: 31046917 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 15, 2019 Category: Dermatology Authors: Martínez-Doménech Á, García-Legaz-Martínez M, Magdaleno-Tapial J, Giácaman M, Hernández-Bel P, Pérez-Ferriols A Tags: Dermatol Online J Source Type: research

Metastatic squamous cell carcinoma arising in the setting of folliculitis decalvans.
We present a patient with severe, chronic FD who developed metastatic squamous cell carcinoma of the scalp. PMID: 31046918 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 15, 2019 Category: Dermatology Authors: Esaa F, Shah PR, Dolohanty LB Tags: Dermatol Online J Source Type: research

Corrigendum: A novel ultraviolet B home phototherapy system: Efficacy, tolerability, adherence, and satisfaction.
Abstract The original article was published on February 15, 2019 and corrected on April 15, 2019. The third pair of panes of Figure 2 were reversed, such that the pane previously depicted on the left was after phototherapy. The corrected sequence is now before phototherapy, on the left, and after, on the right. This change appears in the revised online PDF copy of this article. PMID: 31046919 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 15, 2019 Category: Dermatology Authors: Unrue EL, Cline A, Collins A, Nguyen VH, Pelle MT, Blake P, Feldman SR Tags: Dermatol Online J Source Type: research

Animated video consultation for reducing pre-operative anxiety in dermatologic surgery.
Abstract Pre-operative anxiety is common in patients undergoing dermatologic surgery. This pilot study aimed to evaluate whether the addition of an animated educational video to conventional in-person surgery consultation helps to reduce pre-operative anxiety related to anesthesia, surgery, wound care, and post-operative pain in patients undergoing outpatient dermatologic surgery. Patients awaiting dermatologic surgery were randomized into groups with conventional consultation, or video with consultation prior to undergoing their procedure. The conventional consultation group received conventional consultation wit...
Source: Dermatol Online J - March 15, 2019 Category: Dermatology Authors: Platto JF, Maarouf M, Hendricks A, Kurtzman DJ, Shi VY Tags: Dermatol Online J Source Type: research

Revised Mohs surgery care guidelines for squamous cell carcinoma in-situ are overdue.
Abstract The treatment of cutaneous squamous cell carcinoma in situ by Mohs micrographic surgery is currently deemed as appropriate by the Mohs Appropriate Use Criteria. However, squamous cell carcinoma in situ is a very superficial, indolent, low-risk tumor amenable to destructive and non-surgical treatments. It is uncommon for squamous cell carcinoma in situ to have progressed to invasive malignancy subsequent to definitive management. The suggestion that squamous cell carcinoma in situ on certain anatomic locations has a poorer prognosis is widely assumed but lacks an evidence base. We recommend that most prima...
Source: Dermatol Online J - March 15, 2019 Category: Dermatology Authors: Carley SK, Dixon A, Zachary CB, Steinman HK Tags: Dermatol Online J Source Type: research

Adherence to a novel home phototherapy system with integrated features.
CONCLUSIONS: By implementing a smartphone application and web-based portal with the home phototherapy system, patients have multiple mechanisms in place to ensure adherence. PMID: 30982300 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 15, 2019 Category: Dermatology Authors: Cline A, Unrue EL, Collins A, Feldman SR Tags: Dermatol Online J Source Type: research

Sexual dimorphism and transgender medicine: appealing to a viewer's sense of beauty.
Abstract Sexual dimorphism - the phenotypic structural differences between male and female faces - has been shown to be an important universal component of beauty. This concept plays a key role in facial feminization surgery (FFS), which consists of contouring and reshaping features of the skull itself to alter the foundation of the face. FFS has been shown to improve quality of life among transgender women and therefore an understanding of the procedure and the concept of sexual dimorphism is key for plastic surgeons, dermatologists, and other healthcare providers. PMID: 30982301 [PubMed - in process] (...
Source: Dermatol Online J - March 15, 2019 Category: Dermatology Authors: Rajanala S, Maymone MB, Vashi NA Tags: Dermatol Online J Source Type: research